CN104398962A

CN104398962A - Chinese medicinal composition for treating spleen and kidney deficiency type lumbar muscle degeneration and preparation method thereof

Info

Publication number: CN104398962A
Application number: CN201410699000.5A
Authority: CN
Inventors: 不公告发明人
Original assignee: Qingdao Shen Da New And High Technology Development Corp Ltd
Current assignee: Qingdao Shen Da New And High Technology Development Corp Ltd
Priority date: 2014-11-27
Filing date: 2014-11-27
Publication date: 2015-03-11

Abstract

The invention provides a Chinese medicinal composition for treating the spleen and kidney deficiency type lumbar muscle degeneration. An oral preparation of the Chinese medicinal composition comprises the following crude drugs: fructus amomi, poria cocos, yam, the bark of ash, mangnolia officinalis, teasel root, light wheat, radix achyranthis bidentatae, fructus rosae laevigatae, radix angelicae tuhuo, parasitic loranthus, polygonum cuspidatum, eucommia ulmoides, rhizoma cibotii, beefwood-like clubmoss herb, drynaria rhizome, ligusticum wallichii, erodium stephanianum willd, red paeony root, rhizoma corydalis, pberetima, fructus psoraleae and dried tangerine or orange peel; an external medicament of the Chinese medicinal composition comprises the following crude drugs: frankincense, dragon blood, teasel root, radix clematidis, red flower, rhizoma homalonemae, tripterygium wilfordii, cassia twig, radix aconiti preparata, scorpio, tuberculate speranskia herb, polygonum cuspidatum, dog button, ground beeltle and angelica root. By internal administration and external application, the Chinese medicinal composition can warm channels to remove coldness, activate blood to remove stasis, eliminate phlegm and dredge collaterals, invigorate the kidney and strengthen the loins and is good at activating blood to remove stasis, expelling wind and cold, diminishing swelling and relieving pain and strengthening tendons and bones. The Chinese medicinal composition has a powerful repairing effect on back pain and lumbar muscle degeneration. According to the technology, the Chinese medicinal composition has the advantages of convenience for administration, direct action on the affected part, high targeting, easiness for preparing the preparation, low cost and the like, can treat both manifestation and the root cause of the disease by adopting Chinese medicinal herb treatment, is safe and effective and is low in treatment cost.

Description

A kind ofly treat Chinese medicine composition of spleen kidney both deficiency type lumbar muscle strain and preparation method thereof

Technical field

The present invention relates to the medicinal preparation containing deriving from plant, animal or mineral component, particularly a kind ofly treating Chinese medicine composition of spleen kidney both deficiency type lumbar muscle strain and preparation method thereof.

Background technology

Waist is kidney mansion, spleen governing muscles, asthenia of both the spleen and kidney, and be bound to waist soreness.Treat this disease and to suffer from a deficiency of the kidney, therefore the kidney invigorating emphatically must be treated, take into account and control spleen.And temper one is prosperous, kidney qi must be filled, and skeleton is naturally strong.Chronic lumbar muscle strain is a kind of eliminating lumbar vertebra pathological changes and serious internal organs organic disease, and with a kind of commonly encountered diseases of lumbar soft tissue committee cardinal symptom.This disease, objective determination often can not find any positive classification, but sufferer very pain, namely generally all possessing slightly stands tires out, and sitting must bitterly, be had a rest slightly slow; The feature that fatigue increases the weight of.Pain lumbar muscle strain, also known as functional lumbago, chronic lower lumbar injury, lumbar and breech myofacia inflammation etc., being the chronic traumatic inflammation of waist muscle and attachment point fascia or periosteum in fact, is one of common cause of lumbago, cardinal symptom is waist or lumbosacral region distending pain, aches, recurrent exerbation, pain can change, as fatigue in the daytime increases the weight of with climate change or tired degree, heavy time light when can alleviate after rest, for common clinical, frequently-occurring disease, pathogenic factors is more.It accumulates over a long period, and can make myofibrosis, even tear on a small quantity, forms cicatrix, fiber rope bar or adhesion, leaves over long-term chronic lumbago and backache.

Mostly the chronic lumbar muscle strain cause of disease is by after acute lumbar muscle sprain and prolonged and repeated lumbar muscle strain.Or treatment not in time, processing method is improper.Prolonged and repeated excessive waist movement and over load, as seat over a long time, for a long time station or from position of bending over to the hand-held weight of orthostatism, lift thing, psoas muscle all can be made to be in high-tension state for a long time, can cause chronic lumbar muscle strain in the course of time.Chronic lumbar muscle strain and weather, environmental condition also have certain relation, and the too low or humidity of temperature too mostly can inspire or increase the weight of lumbar muscle strain.

Most of patients has the pain history of several weeks or several months, or has lumbago history of attack repeatedly.Lumbago degree weight differs, and severe patient can affect and stand up and sitting.After general rest, symptom alleviates, cough, sneeze or stool time firmly, all can make that the pain increased.Symptom two, lower limb radiating pain: lower limb sciatic nerve territory, side radiating pain is the cardinal symptom of primary disease, lumbago of being everlasting disappears or occurs when alleviating.Pain, by buttocks, is radiated on rear side of sub-thigh, little leg outer side gradually, and outside the developed into instep had, heel or vola, impact is stood and walked.If protuberance is in central authorities, then in cauda equina nerve symptom, the outstanding then radiation of bilateral may be bilateral or alternately.Symptom three, waist moving obstacle: waist activity all effected in every respect, it is obvious for stretching obstacle after outstanding.Small number of patients is obviously limited when anteflexion.Symptom four, scoliosis: most of patients has lumbar spine lateral bending in various degree.Convex direction, side can show the position of outthrust and the relation of nerve root.

Spleen kidney both deficiency type lumbar muscle strain shows: lumbago, and palpitation and short breath is become thin, rare pool of defecating, and leucorrhea is many, and appetite declines, tastelessness, and pulse condition is heavy carefully unable, pale tongue, white and thin fur or thick in vain.Waist is kidney mansion, spleen governing muscles, asthenia of both the spleen and kidney, and be bound to waist soreness.Treat this disease and to suffer from a deficiency of the kidney, therefore the kidney invigorating emphatically must be treated, take into account and control spleen.And temper one is prosperous, kidney qi must be filled, and skeleton is naturally strong.

Plain Questions of Huangdi's Internal Classic arteries and veins wants precise and tiny opinion to point out: " incapable of turning round, kidney is by exhausted for waist person, house of kidney." illustrate that suffering from a deficiency of the kidney is lumbago Etiological." seven loose rock collection lumbagos " is pointed out: " so pain have deficiency and excess point, so-called empty person, be the spiritual asthenia of qi and blood of two kidneys also, all speech deficient syndromes, all two kidneys are from sick ear.So-called real person, non-kidney man, from real, is among two waist meridians blood vessels, and the institute wet for wind and cold invades, and dodges the institute that Na files gas and hinders, and among waist internal cavity, for damp-phlegm blood stasis stagnates obstructed and be pain, demonstrate,proves to debate know and divide and rule when foundation arteries and veins.At clinical middle employing kidney tonifying, essence replenishing, blood circulation promoting and blood stasis dispelling, the treatment way treatment lumbar muscle strain of removing obstruction in the collateral to relieve pain goes out have received good clinical efficacy.

The method for the treatment of lumbar muscle strain, western medicine is thought more, and also do not have ability that the pathology of lumbar muscle strain is reversed at present, patient can only use analgesic, pain killer injection, antiinflammatory etc. to carry out relief of symptoms.But, usually emphasize that entirety treats, motherland's medical science for the treatment of must aim at the pathogenesis of disease early have research to this disease, and be longer than blood circulation promoting and blood stasis dispelling, Anshen Bunao, expelling wind and cold, Repercusion analgesia, bone and muscle strengthening traditional black plaster very good clinical therapeutic efficacy is achieved to it.

Plaster external application is excited nerve tip, and by reflection, blood vessel dilating, promotes local blood circulation, improve surrounding tissue nutrition, impel Liquid Absorption in bone, makes it to return produce and absorb dynamic equilibrium, reaches and eliminates osteodynia inflammation and the object of fully recovering." Chu is sick in interior, must shape in outer ".When symptom appears in certain position of human body, according to the trend of meridians, to launch at pain in the lumbar region position and corresponding acupuncture point thereof during treatment simultaneously, and carry out cream cave combined treatment the corresponding course for the treatment of in accordance with this disease, to reach treating both the principal and secondary aspects of a disease, thoroughly cut off the object of recurrence root, external application stimulating acupoint, dredging microcirculation, blood vessel dilating, promotes local blood circulation, improve surrounding tissue nutrition, impel bone Liquid Absorption, make it to return and produce and absorb dynamic equilibrium, reach and eliminate osteodynia inflammation and the object of fully recovering.Internal and external medicine can also alleviate the side reaction that Western medicine brings, thus demonstrates its advantage place.

Summary of the invention

Technical problem to be solved by this invention is, the method for the treatment of lumbar muscle strain, and western medicine is thought more, and also do not have ability that the pathology of lumbar muscle strain is reversed at present, patient can only use analgesic, pain killer injection, antibiotic medicine etc. to carry out relief of symptoms; Drug therapy generally adopted chemical drugs and Chinese patent medicine in the past, and chemical drugs is soon effective, and these medicine toxicities are comparatively large, occur that lack of appetite is indigestion and loss of appetite, nausea and vomiting, stomach discomfort after a lot of patient medication.And the application of Chinese medicine is except treating pain in the lumbar region, lumbar muscle strain; Most critical takes for a long time to be free from side effects, and blood circulation promoting and blood stasis dispelling of the present invention, expelling wind and cold, Repercusion analgesia, bone and muscle strengthening, can also alleviate the side reaction that Western medicine brings, thus demonstrate its advantage place.

For solving the problems of the technologies described above, the invention provides a kind of Chinese medicine composition for the treatment of spleen kidney both deficiency type lumbar muscle strain, be made up of endo-medicine and external used medicine, described endo-medicine comprises the crude drug of following weight portion: Fructus Amomi 10 ~ 20 parts, 10 ~ 20 parts, Poria, Cortex Magnoliae Officinalis 10 ~ 20 parts, Radix Gentianae Macrophyllae 10 ~ 20 parts, Rhizoma Dioscoreae 10 ~ 20 parts, Radix Dipsaci 10 ~ 20 parts, Herba Schizonepetae 10 ~ 20 parts, Radix Achyranthis Bidentatae 10 ~ 20 parts, Fructus Rosae Laevigatae 10 ~ 20 parts, Radix Angelicae Pubescentis 10 ~ 20 parts, Herba Taxilli 10 ~ 20 parts, Rhizoma Polygoni Cuspidati 10 ~ 20 parts, the Cortex Eucommiae 10 ~ 20 parts, Rhizoma Cibotii 10 ~ 20 parts, Lycopodium casuarinoides Spring 10 ~ 20 parts, Rhizoma Drynariae 10 ~ 20 parts, Rhizoma Chuanxiong 10 ~ 20 parts, geranium 10 ~ 20 parts, Radix Paeoniae Rubra 10 ~ 20 parts, Rhizoma Corydalis 10 ~ 20 parts, Pheretima 10 ~ 20 parts, Fructus Psoraleae 10 ~ 20 parts, Pericarpium Citri Reticulatae 10 ~ 20 parts,

External used medicine comprises the crude drug of following parts by weight: Olibanum 10 ~ 20 parts, Sanguis Draxonis 10 ~ 20 parts, Radix Dipsaci 10 ~ 20 parts, Radix Clematidis 10 ~ 20 parts, 10 ~ 20 parts, Flos Carthami, Rhizoma Homalomenae 10 ~ 20 parts, Radix Tripterygii Wilfordii 10 ~ 20 parts, Ramulus Cinnamomi 10 ~ 20 parts, Radix Aconiti Preparata 10 ~ 20 parts, Scorpio 10 ~ 20 parts, Herba speranskiae tuberculatae 10 ~ 20 parts, Rhizoma Polygoni Cuspidati 10 ~ 20 parts, Semen Strychni 10 ~ 20 parts, Eupolyphaga Seu Steleophaga 10 ~ 20 parts, the Radix Angelicae Dahuricae 10 ~ 20 parts.

The Chinese medicine composition of described treatment spleen kidney both deficiency type lumbar muscle strain, the crude drug of following parts by weight can be comprised: Fructus Amomi 10 ~ 15 parts in endo-medicine described in it, 10 ~ 15 parts, Poria, Cortex Magnoliae Officinalis 10 ~ 15 parts, Radix Gentianae Macrophyllae 10 ~ 15 parts, Rhizoma Dioscoreae 10 ~ 15 parts, Radix Dipsaci 10 ~ 15 parts, Herba Schizonepetae 10 ~ 15 parts, Radix Achyranthis Bidentatae 10 ~ 15 parts, Fructus Rosae Laevigatae 10 ~ 15 parts, Radix Angelicae Pubescentis 10 ~ 15 parts, Herba Taxilli 10 ~ 15 parts, Rhizoma Polygoni Cuspidati 10 ~ 20 parts, the Cortex Eucommiae 10 ~ 20 parts, Rhizoma Cibotii 10 ~ 20 parts, Lycopodium casuarinoides Spring 10 ~ 20 parts, Rhizoma Drynariae 10 ~ 20 parts, Rhizoma Chuanxiong 10 ~ 20 parts, geranium 10 ~ 20 parts, Radix Paeoniae Rubra 10 ~ 20 parts, Rhizoma Corydalis 10 ~ 20 parts, Pheretima 10 ~ 20 parts, Fructus Psoraleae 10 ~ 20 parts, Pericarpium Citri Reticulatae 10 ~ 20 parts,

The crude drug of following weight portion can be comprised: Olibanum 10 ~ 15 parts, Sanguis Draxonis 10 ~ 15 parts, Radix Dipsaci 10 ~ 15 parts in external used medicine, Radix Clematidis 10 ~ 15 parts, 10 ~ 15 parts, Flos Carthami, Rhizoma Homalomenae 10 ~ 15 parts, Radix Tripterygii Wilfordii 10 ~ 15 parts, Ramulus Cinnamomi 10 ~ 20 parts, Radix Aconiti Preparata 10 ~ 20 parts, Scorpio 10 ~ 20 parts, Herba speranskiae tuberculatae 10 ~ 20 parts, Rhizoma Polygoni Cuspidati 10 ~ 20 parts, Semen Strychni 10 ~ 20 parts, Eupolyphaga Seu Steleophaga 10 ~ 20 parts, the Radix Angelicae Dahuricae 10 ~ 20 parts.

The Chinese medicine composition of described treatment spleen kidney both deficiency type lumbar muscle strain, the crude drug of following weight portion can also be comprised: Fructus Amomi 10 ~ 20 parts in endo-medicine described in it, 10 ~ 20 parts, Poria, Cortex Magnoliae Officinalis 10 ~ 20 parts, Radix Gentianae Macrophyllae 10 ~ 20 parts, Rhizoma Dioscoreae 10 ~ 20 parts, Radix Dipsaci 10 ~ 20 parts, Herba Schizonepetae 10 ~ 20 parts, Radix Achyranthis Bidentatae 10 ~ 20 parts, Fructus Rosae Laevigatae 10 ~ 20 parts, Radix Angelicae Pubescentis 10 ~ 20 parts, Herba Taxilli 10 ~ 20 parts, Rhizoma Polygoni Cuspidati 10 ~ 15 parts, the Cortex Eucommiae 10 ~ 15 parts, Rhizoma Cibotii 10 ~ 15 parts, Lycopodium casuarinoides Spring 10 ~ 15 parts, Rhizoma Drynariae 10 ~ 15 parts, Rhizoma Chuanxiong 10 ~ 15 parts, geranium 10 ~ 15 parts, Radix Paeoniae Rubra 10 ~ 15 parts, Rhizoma Corydalis 10 ~ 15 parts, Pheretima 10 ~ 15 parts, Fructus Psoraleae 10 ~ 15 parts, Pericarpium Citri Reticulatae 10 ~ 15 parts,

The crude drug of following weight portion can also be comprised: Olibanum 10 ~ 20 parts, Sanguis Draxonis 10 ~ 20 parts, Radix Dipsaci 10 ~ 20 parts in external used medicine, Radix Clematidis 10 ~ 20 parts, 10 ~ 20 parts, Flos Carthami, Rhizoma Homalomenae 10 ~ 20 parts, Radix Tripterygii Wilfordii 10 ~ 20 parts, Ramulus Cinnamomi 10 ~ 15 parts, Radix Aconiti Preparata 10 ~ 15 parts, Scorpio 10 ~ 15 parts, Herba speranskiae tuberculatae 10 ~ 15 parts, Rhizoma Polygoni Cuspidati 10 ~ 15 parts, Semen Strychni 10 ~ 15 parts, Eupolyphaga Seu Steleophaga 10 ~ 15 parts, the Radix Angelicae Dahuricae 10 ~ 15 parts.

For solving the problems of the technologies described above, the present invention also provides a kind of preparation method for the treatment of the Chinese medicine composition of spleen kidney both deficiency type lumbar muscle strain, and the dosage form of endo-medicine described in it is tablet, and its preparation method comprises:

A. all crude drug are put into ethanol heating and refluxing extraction 2 times, as component 1;

B. get the medicinal residues after above-mentioned ethanol extraction again, the heating and refluxing extraction that adds water 2 times, as component 2;

C. said components merged, spraying dry after decompression recycling ethanol, obtains medicated powder; Add tabletting after starch.

In described step a, first all crude drug are cut into coarse granule, then put into ethanol, soak more than 2 hours, heating extraction 2 times, each 1-2 hour, removes supernatant, merge extractive liquid, 100-120 order filters, then is the ultrafiltration post ultrafiltration of 5000-10000 through the molecular weight that dams, when ultrafiltrate concentrating under reduced pressure relative density is 80 DEG C 1.38 extractum, stand for standby use, becomes component 1.

In described step b, the medicinal residues that above-mentioned ethanol extraction is crossed are added water heating 1 ~ 2 hours reflux accounting for its quality 10 times amount and extract 2 times; Extraction time is 2 hours, 1 hour; Merge 2 extracting solution, extracting solution is centrifugal by tubular type, obtains centrifugal liquid, and centrifugal liquid is crossed D 101 macroporous resin and adsorbed, and first washes remove impurity with water, then carries out eluting with the ethanol of 70%, collects eluent, concentrating under reduced pressure, becomes extractum standing, for subsequent use as component 2.

In described step c, above-mentioned two kinds of component extractum are merged, decompression recycling ethanol to be concentrated into liquor strength be 0.1g crude drug/mL, after sucking filtration, when the relative density of filtrate is about 20 DEG C 1.38; Above-mentioned filtrate is the macroporous adsorptive resins of 10L through volume, first uses deionized water or the distilled water eluting of 10 times of resin column volumes, then uses 95% ethanol elution of 5 times of resin column volumes, collect ethanol elution, remove solvent, obtain crude drug medicated powder, then add starch tabletting.

For solving the problems of the technologies described above, the present invention also provides a kind of preparation method for the treatment of the Chinese medicine composition of spleen kidney both deficiency type lumbar muscle strain, and the dosage form of described external used medicine is plaster, and its preparation method comprises:

First Radix Clematidis, Sanguis Draxonis, Olibanum, Ramulus Cinnamomi and the Rhizoma Homalomenae way of distillation are vaporized into crystallization, pulverize for subsequent use; Again other crude drug of above-mentioned parts by weight are added in the Oleum Sesami accounting for its 5-10 times weight portion and soak 3-5 days, heating extraction, first big fire is boiled, Oleum Sesami boiling after firepower reduce, endure to pharmaceutical presentations be dark brown, inner coke yellow, pull medicinal residues out, continued to temper by medicine oil, and constantly stir, refining is to the beading that drips; Again Plumbum preparatium is fried to vermilion, removing moisture, cross 100 mesh sieve removing impurity; Slowly added by Plumbum preparatium in the medicine oil refined, constantly stir, become the thick paste of black, in the slightly cold rear impouring cold water of the plaster refined, soak 5-10 days, change water every day once, releasing fire-toxin, the crystalline powder then mixing vaporization stirs.

For solving the problems of the technologies described above, the present invention reoffers a kind of preparation method for the treatment of the Chinese medicine composition of spleen kidney both deficiency type lumbar muscle strain, and the dosage form of described external used medicine is ointment, and preparation method comprises:

A. Radix Clematidis, Sanguis Draxonis, Olibanum, Ramulus Cinnamomi and the Rhizoma Homalomenae way of distillation are vaporized into crystallization, pulverize for subsequent use;

B. all the other crude drug medicines are added alcohol heating reflux and extract 2 times;

C. the medicinal residues after above-mentioned ethanol extraction are got again, the alcohol heating and refluxing extraction that adds water 2 times;

D. merged by above-mentioned 2 kinds of extracting solution, add the crystallization prepared after decompression recycling ethanol concentrates, the glycerol that is in harmonious proportion stirs, fill after sterilization.

In described step a, first Radix Clematidis, Sanguis Draxonis, Olibanum, Ramulus Cinnamomi and the Rhizoma Homalomenae way of distillation can be vaporized into crystalline particle, then be ground into fine powder for subsequent use; In described step b, all the other crude drug can be added and account for its quality 5 ~ 8 times amount alcohol heating reflux and extract 2 times, described each 1 ~ 2 hour, 2 extracting solution be merged and leaves standstill; In described step c, the medicinal residues that above-mentioned ethanol extraction is crossed can be added water heating 1 ~ 2 hours reflux accounting for its quality 10 times amount and extract 2 times; Extraction time is 2 hours, 1 hour; Merge 2 extracting solution, extracting solution is centrifugal by tubular type, obtains centrifugal liquid, and centrifugal liquid is crossed D 101 macroporous resin and adsorbed, and first washes remove impurity with water, then carries out eluting with the ethanol of 70%, collects eluent, one-tenth extractum stand for standby use; In described steps d, above-mentioned 2 kinds of extracting solution can be merged, when concentrating under reduced pressure relative density is 80 DEG C 1.35 filtrate, reclaim ethanol, by gained filtrate adjustment proportion to 1.50, reduce pressure to obtain extractum, add the crystalline powder prepared, the glycerol that is in harmonious proportion stirs furnishing emulsifiable paste.

The Chinese medicine composition of described treatment spleen kidney both deficiency type lumbar muscle strain, its endo-medicine dosage form can be: sugar coated tablet, film coated tablet, enteric coated tablet, hard capsule, soft capsule, oral liquid, suck agent, granule, electuary, honey pill agent, powder, sublimed preparation, solution, injection, suppository, plaster, syrup; External drug dosage forms can be: fumigant, ointment, liniment, tincture, ointment, powder, patch, gel and spray.

Externally used paste heating of the present invention is concentrated into pasty state, and be in harmonious proportion spread on lumbago place with wine, vinegar, Mel, pasting medicine part need clean, and fixes with preservative film, medical adhesive tape.

Orally taken and externally of the present invention share dispelling cold by warming the meridian, blood circulation promoting and blood stasis dispelling, eliminating phlegm dredging collateral, strong kidney can strengthen waist, and to be longer than blood circulation promoting and blood stasis dispelling, expelling wind and cold, Repercusion analgesia, bone and muscle strengthening.This technology has convenient drug administration, through patient part, the advantages such as targeting is strong, and medicament is easy to manufacture, with low cost.The present invention adopts the Chinese crude drug of different properties, has carried out scientific compatibility, can reach desirable therapeutic effect, and safety, without any side effects, the application of Chinese medicine is except treating lumbar muscle strain, the side reaction that Western medicine brings can also be alleviated, thus demonstrate its advantage place.Most critical takes for a long time also can not cause side effect, treatment by Chinese herbs energy treating both the principal and secondary aspects of a disease, and safely, effectively, medical expense is lower.The present invention is easy to use, and cheap, easy to use, can create good social value and economic interests.

Detailed description of the invention

Waist is kidney mansion, spleen governing muscles, asthenia of both the spleen and kidney, and be bound to waist soreness.Treat this disease and to suffer from a deficiency of the kidney, therefore the kidney invigorating emphatically must be treated, take into account and control spleen.Spleen kidney is all benefited.And temper one is prosperous, kidney qi must be filled, then waist strengthens flesh by force, and lumbago is aching and limp from removing ear.Except except taking medicine, suitably doing some waist movements and take exercise, is also very important auxiliary treatment measure.

Lumbar muscle degeneration belongs to motherland's medical science pain in the lumbar region or arthromyodynia category, and its cause of disease is most by the damp that is affected by the cold, and the QI-blood circulation that wound is strained and caused is smooth, and meridians are obstructed, through flow of QI being obstructed, and stagnation of QI and blood may bring about pain.Modern medicine thinks that primary disease Etiological is degenerative change and acute and chronic trauma; thus cause mechanical pressure; chemistry or inflammatory thing the dural sac at fibrous ring rear portion or the stimulation of nerve root are occurred the paraesthesia of corresponding nerve distribution area or Ipsilateral lower limb exercise limited; waist muscle anxiety or spasm increase again the pressure of intervertebral disc conversely and increase the weight of peripheral tissue edema, and symptom is occurred repeatedly.Sickness rate is high in recent years, and the age is tending towards rejuvenation, and irrational life style and special work post are also impel one of this pathogenetic cause of disease.

Lumbar muscle degeneration belongs to impediment syndrome category, and because waist is suffered from cold, the reasons such as intrusion of pathogenic wind-cold-dampness local or traumatic injury sprain and contusion, make the waist meridian qi and blood stasis of blood stagnant not smooth, " stagnation of QI and blood may bring about pain "." Yizong Jinjian bonesetting heart method main idea " cloud: " stagnation of QI-blood, for swelling as pain, should use massotherapy, and by its meridians, with the gas of logical closing, rubbing, it stops up poly-, and swollen with dissipating blood stasis knot, its trouble can be healed." simple means treatment lumbar muscle degeneration effect can not get accreditation, and comprehensive means more receives publicity.Non-operative treatment is the basic therapy of lumbar muscle degeneration, and the overwhelming majority all can be eased or cure through Comprehensive Treatment.

Plaster external application is excited nerve tip, and by reflection, blood vessel dilating, promotes local blood circulation, improve surrounding tissue nutrition, impel Liquid Absorption in bone, makes it to return produce and absorb dynamic equilibrium, reaches and diminishes inflammation and the object of fully recovering." Chu is sick in interior, must shape in outer ".When symptom appears in certain position of human body, according to the trend of meridians, to launch at its corresponding acupuncture point of either side of the small of the back during treatment simultaneously, and carry out cream cave combined treatment the corresponding course for the treatment of in accordance with this disease, to reach treating both the principal and secondary aspects of a disease, thoroughly cut off the object of recurrence root, external application stimulating acupoint, dredging microcirculation, blood vessel dilating, promotes local blood circulation, improve surrounding tissue nutrition, impel Liquid Absorption, make it to return and produce and absorb dynamic equilibrium, reach and diminish inflammation and the object of fully recovering.Internal and external medicine can also alleviate the side reaction that Western medicine brings, thus demonstrates its advantage place.

Prescription of the present invention: Radix Achyranthis Bidentatae evacuation of pus, expelling pus and promoting granulation; Radix Angelicae Sinensis promoting the circulation of blood blood stasis dispelling, invigorating middle warmer gas; Rhizoma Drynariae, Fructus Psoraleae the kidney invigorating bone strengthening, continue and hinder pain relieving; Eupolyphaga Seu Steleophaga endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain; Radix Angelicae Pubescentis promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming; Rhizoma Corydalis, Radix Dipsaci, Radix Paeoniae Alba activating QI to alleviate the depression, dispeiling pathogenic wind and removing dampness, promoting blood circulation and stopping pain; Herba Taxilli dispelling the wind and dampness pathogens arthralgia; Radix Clematidis expelling wind and dampness; Dispersing cold for relieving pain; Radix Salviae Miltiorrhizae blood-activating kidney-tonifying sun, bone and muscle strengthening, Lycopodium casuarinoides Spring, geranium wind-damp dispelling; Separate arthralgia pain; Orally taken and externally of the present invention share dispelling cold by warming the meridian, blood circulation promoting and blood stasis dispelling, eliminating phlegm dredging collateral, strong kidney can strengthen waist, and to be longer than blood circulation promoting and blood stasis dispelling, expelling wind and cold, Repercusion analgesia, bone and muscle strengthening.

Rhizoma Drynariae is bitter, temperature.Return kidney, Liver Channel.Function the kidney invigorating bone strengthening, continues and hinders pain relieving.For lumbago due to renal deficiency, Hiccough and deaf, odontoseisis, falling winks frustrates, injured bone; External treatment alopecia areata, vitiligo." Japan hanako materia medica " carries it: control malignant boil, lose rotten meat, parasite killing.

Fructus Psoraleae acrid in the mouth; Bitter in the mouth; Warm in naturely return through kidney; Pericardium; Spleen; Stomach; Lung meridian function cures mainly: reinforcing the kidney and supporting YANG; Helping inspiration to relieve asthma; Warming spleen and stopping diarrha.Main insufficiency of kidney-YANG; Below element deficiency and cold; Chills and pain of the waist and kness; Sexual impotence essence; Frequent micturition; The enuresis; Failure of the kidney in receiving QI; Dyspnea due to deficiency is more than; Asthenia of both the spleen and kidney; Stool chronic diarrhea." Bencao Jingshu ": Fructus Psoraleae, energy warming the kidney; Raw sun in the moon, the key medicine of excessive fire benefit soil also.Its main five kinds of strain and seven kinds of impairment, the disease of lid edge impairment caused by overstrain, a lot of in asthenia of both the spleen and kidney, with its can warming the kidney, mend fire with the immature soil, then in kidney kidney-Yang be so incensed that mend and rise, then can digesting food, steam waste matter and change precise and tiny.Spleen-QI transporting the essence to the whole body is attributed to lung, supports the five internal organs with honor, therefore the labor of main the five internal organs.Seven emotions hinder disease of viscera connecting with this channel.Wind cold caused by deficiency person, because yang-energy is decayed, and the then air-cooled visitor that takes advantage of a weak point in opponent's defence so that bone marrow wound loses, the cold essence stream of kidney, and kidney governing bones store essential substances, marrow be essence this, the gas of kidney-Yang is solid, and namely, card is shown in, solid itself and yang-energy life, then front card removes in vain.Man is based on essence, and married woman is based on blood, and married woman vim and vigour person, also still man's sun kidney that declines is cold and be the disease of blood prostration QI collapse caused by exhaustion of QI of the spleen and kidney, and the cold essence stream of the kidney with man also.

Radix Dipsaci, Chinese medicine name is the root of Dipsacaceae herbaceos perennial Radix Dipsaci, gains the name because of energy " synthetism of continuous folding ".Autumn excavates, and removing root head and fibrous root, be dried to half-dried with low baking temperature, when bank up " diaphoresis " is to inner virescence, then dries." the southern regions of the Yunnan Province book on Chinese herbal medicine ": " meridians determine in tonifying liver, bone and muscle strengthening, and only in warp, (muscles and bones) is ached, and antiabortive, control married woman leucorrhea, tissue regeneration promoting blood, removing blood stasis with potent drugs blood, fall stillborn fetus, and cough-relieving is coughed hemoptysis, controls red white turbid urine.”

Geranium nature and flavor are pungent, bitter, flat.Gui Jing: return liver,kidney,spleen warp.Function cures mainly: wind-damp dispelling, the meridian dredging, antidiarrheal profit.For rheumatic arthralgia, numbness contracture, muscles and bones is ached, dysentery.Control bones and muscles pain, current meridians, remove all wind: fresh Herba Erodii is cleaned, and puts 100 jin in copper pot, decocts with water secondary, filter, then filtrate is concentrated into about 30 jin, add beverage wine five liang, boil ten minutes, finally add ripe Mel six jin, mixing is mixed thoroughly, boils 20 minutes, treats cold charge tank.(" Chinese medicine shape sex experience differential method " Herba Erodii cream).

Lycopodium casuarinoides Spring, rectification of name: rattan Lycopodium clavatum, has another name called: stone rattan, lycopodium casuarinoides etc., Latin literary fame: Lycopodiastrum casuarinoides (Spring) Holub ex Dixit.Expelling wind and removing dampness; Relaxing muscles and tendons to promote blood circulation; Improving eyesight; Removing toxic substances.Cure mainly rheumatic arthralgia, lumbar muscle strain, traumatic injury, menoxenia, night sweat, conjunctivitis, nyctalopia, burn due to hot liquid or fire, sore swollen toxin." Traditional Chinese Medicine in Sichuan will " nineteen sixty version: " can relaxing muscles and tendons to promote blood circulation.Dispelling the wind and dampness pathogens arthralgia, traumatic injury, bones and muscles pain, the disease such as menoxenia and tetany.”

Chinese medicine Radix Polygoni Multiflori have Radix Polygoni Multiflori and Radix Polygoni Multiflori Preparata point, direct slicing is used as medicine for Radix Polygoni Multiflori, dries be used as medicine for Radix Polygoni Multiflori Preparata with Semen sojae atricolor liquor after mixing steaming.The function of the two is different: the removing toxic substances of Radix Polygoni Multiflori function, eliminating carbuncle, loosening bowel to relieve constipation, is usually used in treatment scrofula carbuncle sore, rubella pruritus, dryness of the intestine constipation; The invigorating the liver and kidney of Radix Polygoni Multiflori Preparata function, benefiting essence-blood, black beard and hair, bone and muscle strengthening, for blood deficiency and yellow complexion, vertigo and tinnitus, early whitening of beard and hair, soreness of the waist and knees, numb limbs and tense tendons, bleeding not during menses, chronic malaria body void etc.Radix Polygoni Multiflori Preparata of the present invention is the good merchantable brand of invigrating kidney.

Radix Angelicae Pubescentis: expelling wind and dampness; Dispersing cold for relieving pain.For anemofrigid-damp arthralgia; Lumbocrural pain; Few cloudy volt wind headache, headache toothache, " book on Chinese herbal medicine is just ": " specially reason part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels rheumatism, two pain in foot numbness, pruritus due to damp pathogen contracture." modern study, Radix Angelicae Pubescentis has antiinflammatory, analgesia and sedation; Inhibitory action is had to platelet aggregation; And it is not have hypotensive effect, but lasting; Contained bergapten, xanthotoxin etc. have photosensitive and antitumor action.Anemofrigid-damp arthralgia.The pungent loose hardship of these product is dry, and the fragrant temperature of gas is logical, and merit is apt to Eradicates rheumatism, stopping numbness pain, is dispelling the wind and dampness pathogens arthralgia pain principal agent, the arthromyodynia that all wind-cold damp pathogens are caused, no matter for a long time new, all can apply; Enter kidney channel because it is main, property is apt to descending, is especially advisable with waist knee joint, lower limb joints of foot pain subordinate portion cold-damp person.Control the anemofrigid-damp arthralgia of the damp that is affected by the cold, muscle, back, brothers' pain, be often equal to use with Radix Angelicae Sinensis, the Rhizoma Atractylodis Macrocephalae, Radix Achyranthis Bidentatae, as Radix Angelicae Pubescentis soup (" young new book of living "); If with compatibilities such as Herba Taxilli, the Cortex Eucommiae, Radix Ginsengs, arthromyodynia can be controlled with the passing of time weakened body resistance, soreness of the waist and knees, joint joint stuffiness person, as Radix Angelicae Pubescentis et Herba Taxilli Decoction (" prescriptions worth thousand gold ").

Herba Taxilli invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive unit.For rheumatic arthralgia, soreness of the waist and knees, muscles and bones is unable, metrorrhagia through many, blood leaking in gestation, frequent fetal movement; Hypertension." Bencao Jingshu ": Herba Taxilli, its bitter but sweet flavor, its gas is gentle, cold not hot, admittedly should be nontoxic.It cures mainly in detail, take out its elite for one, therefore function compares Sang Yousheng in Mulberry.Lumbago and children's's stiffback, all time of insufficiency of blood, carbuncle is many due to ying-qi heat.Skin does not fill, due to blood deficiency.Tooth person, originator, beneficial blood then sends out China after blood also, and the sufficient then tooth of kidney qi is hard and an eyebrow is long after bone also.Blood contains then tire peace certainly.Woman's metrorrhagia and internal injury deficiency, all events of blood deficiency interior-heat.Disease more than puerperal, all by blood system, agalactia, also by blood deficiency.Incised wound is then hindered entirely in blood.To come up all diseases, there's no one who doesn't or isn't know and have heat institute to send out by blood deficiency, this property of medicine can beneficial blood, thus also lead also.Hold concurrently and can wet by core, therefore also treat numbness.

Radix Paeoniae Rubra nourishes blood cool in nature, and bitter in the mouth acid, is slightly cold, has easing the affected liver of enriching blood, suppressing the hyperactive liver pain relieving.Yin fluid astringing receives the effects such as antiperspirant, is applicable to fever due to yin deficiency, menoxenia, the breast abdomen pain over the hypochondriac region, extremity contraction suddenly, dysentery stomachache, spontaneous sweating, metrorrhagia, the inferior disease of band.Paeoniflorin has antibacterial, antipyretic, antiinflammatory, increase coronary flow, improves the effect of myocardial nutritional flow, blood vessel dilating, antagonism acute myocardial ischemia, anticoagulant, calmness, analgesia, spasmolytic, antiulcer, adjustment blood glucose.Radix Paeoniae Rubra decoct can suppress dysentery bacterium, streptococcus pneumoniae, escherichia coli, Bacillus typhi, Hemolytic streptococcus, bacillus pyocyaneus etc.The condition subject such as the blood deficiency deficiency of YIN, the breast abdomen pain over the hypochondriac region, pain in the hepatic region, cholecystitis, gallstone pain, dysentery stomachache, women's menalgia, spontaneous perspiration easy antiperspirant night sweat, sural spasm, spasm of the limbs pain, uneasy lower limb syndrome are suitable edible.

Radix Achyranthis Bidentatae eliminating blood stasis and inducing menstruation, invigorating the liver and kidney, bone and muscle strengthening, inducing diuresis for treating stranguria syndrome, conducting blood to flow downwards.For amenorrhea, dysmenorrhea, soreness of waist and knee joint, muscles and bones is unable, stranguria, edema, headache, dizzy, toothache, and aphtha is spitted blood, epistaxis." herbal classic ": main cold-damp flaccidity syndrome and arthralgia syndrome, spasm of the limbs, gonalgia can not be bent, and by vim and vigour, fire of getting mildewed in warm conditions is rotten, induced abortion." not Lu ": middle weak breath of curing the wound, male kidney yin disappears, and old man loses excessive, and invigorating middle warmer is absolutely continuous, fills out bone marrow, and except pain and pain along the spinal column in brain, married woman's moon water is obstructed, blood agglomeration, and benefit essence, Li Yin gas, only turns white." property of medicine opinion ": control impotence, kidney tonifying, essence replenishing, by stagnant blood stream knot, helps the twelve regular channels.

The micro-hardship of Rhizoma Polygoni Cuspidati, is slightly cold.Return liver, gallbladder, lung meridian.Function heat-clearing and toxic substances removing, promoting the function of the gallbladder to alleviate jaundice, expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm.For arthralgia, jaundice due to damp-heat, amenorrhea ， WEIJIA, cough with copious phlegm, burn due to hot liquid or fire, injury from falling down, carbuncle sore tumefacting virus." medical center bun will " carries it: hard kidney, strong Yang yi Jing, strengthening bone and muscle, increases strength.Apply to get injured by a fall and lose place, can reunion of fractured tendons and bones.

Radix Gentianae Macrophyllae is Gentianaceae herbaceos perennial, is one of principal agent of the diseases such as dispelling the wind and dampness pathogens arthralgia, tuberculosis hectic fever, jaundice.Especially the best in quality with the Radix Gentianae Macrophyllae of Huang Nan product in Qinghai.Be one of important Chinese medicine of China, begin to be loaded in Shennong's Herbal, be classified as middle product, " the main cold and heat pathogen of Radix Gentianae Macrophyllae, cold-damp migratory arthralgia, arthrodynia of the extremities, Xia Shui, diuresis." for rheumatic arthralgia.Radix Gentianae Macrophyllae function wind-damp dispelling, relaxing muscles and tendons network, be usually used in the diseases such as rheumatic arthralgia, joint contracture, hands and feet caused by paralysis.This product property of medicine embellishes but not dry, no matter cold-damp, damp and hot, arthromyodynia is newly of a specified duration, all can apply.In compatibility, normal being equal to Radix Saposhnikoviae, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Ramulus Mori, is used.In addition, this product is the normal and same use of expelling pathogenic wind from the body surface medicine also, the disease for the treatment of exterior syndrome limb aching pain.

The Cortex Eucommiae is Chinese famous and precious tonic herb.Tool invigorating the liver and kidney, bone and muscle strengthening, blood pressure lowering, many effects such as antiabortive.Shennong's Herbal is classified as top grade.Call its " cure mainly waist and knee, invigorating middle warmer, beneficial vital essence, hard muscles and bones, wet except itching under the moon, dribbling urination.Clothes of a specified duration, make light of one's life by commiting suicide always resistance to." Cortex Eucommiae is Chinese peculiar medical material, its medicinal history is long, has a wide range of applications clinical.Invigorating the liver and kidney, bone and muscle strengthening, antiabortive.Control spinal column ache, foot and knee flaccidity, dribbling urination, uncontrolled urination is itched, vaginal bleeding during pregnancy for falling, frequent fetal movement, hypertension." herbal classic ": " main pain along the spinal column, invigorating middle warmer benefit vital essence, hard muscles and bones, Qiang Zhi, wet except itching under the moon, dribbling urination.

Rhizoma Cibotii is bitter, sweet, temperature.Return liver, kidney channel.Effect: wind-damp dispelling, invigorating the liver and kidney, strong waist knee joint.Cure mainly rheumatic arthralgia, soreness of the waist and knees, weakness of the lower extremities, frequent micturition, the enuresis, leukorrhagia.External application incised wound is stopped blooding.It is strong that " herbal classic " carries its back, shutdown emergency, general arthralgia cold-damp gonalgia, quite sharp old man.Man woman poison wind weak foot, kidney qi is weak, reuniting the fractured tendons and bones, tonification man.Li Shizhen (1518-1593 A.D.) Compendium of Material Medica carries its strong Liver and kidney, and strong bone, controls wind void.

Rhizoma Corydalis cures mainly all pains of trusted subordinate's waist knee joint; Menoxenia; Lump in the abdomen; Metrorrhagia; Puerperal blood faints; Lochiorrhea; Traumatic injury.There are analgesia, calmness, syngignoscism.Analgesic activity: Rhizoma Corydalis powder has analgesic activity, its pain relieving is tired and is about 1/100 of opium; Rhizoma Corydalis total alkaloids, Corydaline, B prime, Chou prime, Kui prime all have analgesic activity, stronger with B prime. various dosage form with alcohol extractum and powder effect strong.

Poria: ancients claim Poria to be " when four god medicine ", because its effect widely, regardless of the four seasons, by it and various compatibility of drugs, no matter cold, temperature, wind, wet all diseases, can play its unique effects.Poria sweet in the mouth, light, property are put down, and are used as medicine and have the function of promoting diuresis to eliminate damp pathogen, strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Poria energy enhancing human body immunity function, pachyman has obvious antitumor and protects the liver dirty effect.Also can be used as food materials use, have cake, Poria cocos congee, very nutritious, taste is gentle.Coordinate to boil water with the precious Ganoderma of fine jade, contribute to treating diabetes, tumor chronic diseases.

Fructus Amomi (Amomumvillosum) has another name called Elettaria cardamomum (L.) Maton, and the Ji Yuan of medicinal Fructus Amomi mainly contains three kinds: a kind of is the spring sand mainly originating in Chinese Guangdong province; A kind of is the shell sand in Chinese Hainan; Also have one to be Amomum xanthioides, main product is in country in Southeast Asia.Wherein, the comparitive study that spring sand (fruit) is used as medicine is remarkable, and quality is also relatively good, and higher reputation is enjoyed in international medical material market.The traditional Chinese medical science is thought, Fructus Amomi mainly acts on the stomach of human body, kidney and spleen, can circulation of qi promoting seasoning, and stomach function regulating is amusing.Fructus Amomi often coordinates with Cortex Magnoliae Officinalis, Fructus Aurantii Immaturus, Pericarpium Citri Reticulatae etc., is suitable for disease such as treatment fullness in the epigastrium and chest, abdominal distention and little diet etc.

Rhizoma Dioscoreae is sweet, flat.Strengthening the spleen and stomach, lung benefiting kidney, tonify deficiency are won.Control anorexia and loose stool, asthenia, breath with cough, frequent micturition, leukorrhagia, to quench one's thirst.Rhizoma Dioscoreae spleen reinforcing stomach invigorating.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, leukorrhagia." book on Chinese herbal medicine is looked for the truth ": " enter in drugs for nourishing yin and should give birth to use, entering spleen reinforcing lung medicine should use by parching to brown." " this genus food, though gas temperature and put down, be the moon of spleen reinforcing lung.Be moistening fur, longue meat, sweet in the mouth is held concurrently salty, again can kidney tonifying reinforcing YIN-essence.”

Cortex Magnoliae Officinalis, another name ZIPU, purple oil Piao, Classification system: Magnolia officinalis Rehd.etWils. are the dry dried bark of Magnoliaceae, magnolia Cortex Magnoliae Officinalis or magnolia officinalis rehd.et wils.var.biloba rehd.et wils., root bark and branch skin.Therapeutical effect is had to diseases such as stagnation of QI due to dyspepsia, abdominal distention constipation, retention of dampness in middle-JIAO.Can also add in cancer drug.Cortex Magnoliae Officinalis acrid in the mouth, warm in nature, there is effect of circulation of qi promoting removing dampness, warming middle-JIAO to relieve pain, lowering the adverse QI to relieve asthma.Cortex Magnoliae Officinalis decoct has stronger antibacterial action to staphylococcus, streptococcus, bloody dysentery bacillus, pasteurellosis bacillus, vibrio cholera; And also have certain mitigation to striped muscle is tetanic.Bark, root bark, flower, seed and bud all can be used as medicine, based on bark, be famous Chinese medicine, have removing dampness intestinal stasis relieving, circulation of qi promoting is relievingd asthma, relieving dyspepsia expectorant, wind dispelling analgesia effect; Seed has improving eyesight QI invigorating effect, and bud is used as gynecological drug.

Pericarpium Citri Reticulatae is bitter, pungent, temperature.Return lung, spleen channel.Regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.Therefore Pericarpium Citri Reticulatae has three major types effect, one is lead cold-evil in the heart, two broken stagnant gas, three strengthening the spleen stomaches.This three large on, Main Function is row QI of the spleen and stomach.The main transmitting and distributing the fluids of taste, therefore QI of the spleen and stomach is capable, can dry, spleen invigorating, reduce phlegm, therefore can say again, Pericarpium Citri Reticulatae temperature can support spleen, pungently can be amusing, bitter can spleen invigorating.Due to the main row QI of the spleen and stomach of Pericarpium Citri Reticulatae, taste are located in middle Jiao, and the gas of middle Jiao passes through, and the gas of three Jiao is also sprung up thereupon.Three Jiao are the organ in charge of water circulation, and current water liquid, accompanies with wetting phase; Again for hiding mansion outside mansion, upper and the heart, lung, lower and liver, kidney.So the effect of Pericarpium Citri Reticulatae can wide and all Zang Fu, wet throughout whole body.Say from lung, then pungent loose lung qi, hardship lets out lung qi, temperatureization cold, can control abundant expectoration cough with asthma, and gas is stopped up food and stopped; Say from the heart, then pungent happy gas, hardship lets out heart-fire, and warm removing dampness is turbid, can control irritable feverish sensation in the chest, and the implication sound of vomiting is smelly; Say from liver, then pungent loose stagnation of liver-QI, liver-fire falls in hardship, warming for eliminaring cold-damp, so its can treating the liver be strongly fragrant heat, drink is stopped eating stagnant; Say from kidney, then pungent profit kidney is dry, and hardship is let out kidney and wet, gentle kidney qi, so it can control life fire deficiency, and indigestion.Certainly, all explanations are all relevant with spleen with wet, so its property of medicine effect performance leeway is larger,

Rhizoma Chuanxiong is usually used in blood-activating and qi-promoting, wind-expelling pain-stopping, and the pungent temperature of Rhizoma Chuanxiong is fragrant dry, walks and does not keep, can go loose, and the up mountain peak that reaches is pushed up; Enter blood system again, descendingly reach the sea of blood.Blood circulation promoting and blood stasis dispelling effect is extensive, the suitable various disease of stagnation of blood stasis; Wind-expelling pain-stopping, effectiveness is excellent, can control the diseases such as wind syndrome of head headache, rheumatic arthralgia.It is gas medicine in blood that former times people calls Rhizoma Chuanxiong, the functions such as pungent loose, the resolving depression of its residence of dangerous speech, sensible, pain relieving.The pungent temperature rise of this product is fallen apart, and all hyperactivity of YANG due to deficiency of YIN and excessive rising of liver-YANG person should not apply; Menorrhagia, anemia of pregnant woman also avoid use.

Fructus Rosae Laevigatae reinforcing the kidney and controlling nocturnal emission, reducing urination and antidiarrheal.Control spermatorrhea, the enuresis, frequent micturition, insufficiency of the spleen dysentery, the deficiency of the lung is breathed with cough, spontaneous sweating, bleeding not during menses." not Lu ": only spermatorrhea." another name for Sichuan Province book on Chinese herbal medicine ": control the splenic diarrhea dysentery, only normal urination, arresting seminal emission gas." the southern regions of the Yunnan Province book on Chinese herbal medicine ": control with the passing of time dysentery, metrorrhagia leukorrhagia, arresting seminal emission spermatorrhea." book on Chinese herbal medicine just ": emesis blood, epistaxis, born fluid, receives sweating due to debility, holds back asthenic fire, beneficial marrow, strengthening bone and muscle, and mend five and hide, nourish blood gas, flat cough, and Dingchuan is anxious, and treat severe palpitation palpitation with fear, only the splenic diarrhea dysentery and little Shui can't help.

Pheretima is the dry body of Annelida Ju Yin section animal Pheretima aspergillum Pheretimaas pergilum (E Perrier), popular Pheretimatschiliensis P vulgarisChen, power simulation P guillelmi (Michaelsen) or comb the region between the heart and the diaphragm hair earthworm PpectiniferaMichaelsen.Heat clearing away is calmed the frightened, and dredging collateral, relievings asthma, diuresis; For cerebral thrombosis, cerebral infarction, coronary heart disease, apoplexy, joint is benumbed, numb limbs and tense tendons, hemiplegia, the diseases such as vascular hypertension.Pheretima extract, Pheretima is extracted by high-tech, successfully develops micro-network health earthworm protein, earthworm protein soft capsule etc. so far.Be widely used in clinical at present, and be used in the heart, cerebrovascular, endocrine more and more, the prevention and treatment of diseases centers such as respiratory system.

External used medicine:

Radix Clematidis expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, expectorant water, the loose hypochondriac lump.Cure mainly gout insensitive impediment, rheumatic arthralgia, numb limbs and tense tendons, chills and pain of the waist and kness, the contracture of muscle arteries and veins, joint stuffiness, beriberi, malaria, lump in the abdomen, tetanus, tonsillitis, all a fishbone or other bone caught in the throat pharynxs." Kaibao Bencao ": main all wind, Xuan Tongwu hides, and go in abdomen cold stagnant, septum cordis expectorant water amasss for a long time, lump in the abdomen Xuan tinea air parcel, bladder place pus aversion to water, the cold pain of waist knee joint and treatment injured.

Flos Carthami is warm in nature, acrid in the mouth.Function cures mainly and is applied to latus rectum of invigorating blood circulation, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury." book on Chinese herbal medicine converge with speech ": Flos Carthami, the medicine of removing blood stasis, promoting the circulation of blood and blood, tune blood also.Main tire produces all kinds of diseases and ailments because blood is for suffering from, or blood is tired of bruise, and coma in silence; Or lochia robs the heart, umbilicus angina abdominis; Or drop slurry is difficult raw; Or afterbirth does not fall, dead fetus in the uterus, be all just before giving birth all cards, non-Flos Carthami can not be controlled.If puerperal blood faints, locked mouth refer to hold in the hand; Or heresy enters blood room, delirium is gone mad; Or blood is vexed interior swollen, sudden syncope with rigidity as extremely, be all puerperal all cards, non-Flos Carthami can not be determined.All as obstructed in amenorrhea and cold and heat are handed over and are done, or expired stomachache and purple black dripping, or injury from falling down and the QI and blood stasis of blood is amassed, or skin infection sufferings and swollenly burst uneasy, and be the card of all disharmony between QI and blood, non-Flos Carthami can not be adjusted.

Olibanum regulating qi and activating blood, analgesic therapy, chases after poison.Control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge." not Lu ": treat edema due to wind pathogen poison swollen, remove bad odor.Treat urticaria to itch poison.Supplement to the Herbal: treat deaf, apoplexy locked mouth, married woman's vim and vigour, can send out wine, manage air-cooled, and only large intestine lets out Bleach, treats all skin ulcers and makes internal diabetes." Japan hanako materia medica ": only cholera, cardiac and abdominal pain.Soft extracts pain relieving is put on flesh.

Its nature and flavor of Ramulus Cinnamomi are pungent, sweet, temperature, enter lung, the heart, urinary bladder channel, cure mainly the conventional drugs for dispelling internal cold of interior cold, there is effect of complement sun, promoting blood circulation, warming the spleen and stomach, normal with invigorating the liver and kidney medicine, fill blood medicine compatibility, treats insufficiency of kidney-YANG, decline of the fire from the gate of life, cold extremities faint pulse, treat coldness and pain in the epigastrium, arthralgia due to cold lumbago with other drugs for dispelling internal cold compatibility, there is the effect of significantly analgesia and anti-cancer and cancer-preventing.Existing various wind dispelling oils medicine is if menthocamphorate, rheumatism wet goods are all containing cassia oil composition.Cure mainly " Sullfortrone " leprous its main component and cassia oil, other side-product of Cortex Cinnamomi has different pharmacological actions as Ramulus Cinnamomi, Fructus cinnamomi japonici, Fructus cinnamomi immaturus, osmanthus cup etc., widely applies in Chinese medicine.

The Radix Angelicae Dahuricae: expelling pathogenic wind from the body surface, dispersing cold for relieving pain, dehumidifying are sensible, detumescence and apocenosis.Can microcirculation in human body be improved, promote skin metabolism, eliminate pigment excess accumulation in the tissue, remove facial colour spot cicatrix, treatment skin bleb wound scabies etc.Shennong's Herbal points out the Radix Angelicae Dahuricae: " longue skin.Moist color, can make face fat." no matter be " a thousand pieces of gold face fat side ", or the empirical formula of preserving youthful looks of the Empress Dowager " beautiful face is fallen apart ", the Radix Angelicae Dahuricae is all the principal agent of making face fat.Be referred to as to remove facial black speck.Modern medicine proves that the Radix Angelicae Dahuricae has certain curative effect to acne, blackhead, acne, at whitening and speckle dispelling, improves microcirculation, and there is unique curative effect delay skin aging aspect.

Scorpio is pungent, flat; Poisonous.Return Liver Channel.Function cures mainly endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula.Scorpion extraction liquid is in mouse tumor experiment, answer 0.2ml (suitable crude drug 0.04g/ only), every large subcutaneous administration after continuous 5 days, when medication the 11st day and drug withdrawal 8 days, be 38.8% and 55.5% to the suppression ratio of cell sarcoma (SRS) solid tumor; To MA 1 breast carcinoma, administration every day is after totally 12 times, and suppression ratio is 51.8%, is 30.4% during drug withdrawal 8 days.To the survival rate comparatively matched group prolongation 12.5%-20.7% of SRS ascitic type band tumor Mus.Result shows there is obvious inhibitory action to the tumor growth of mice with tumor.The Heal complete cell death of Scorpio extract In vitro culture takes off wall.29.2% is extended to LA 1 adenocarcinoma of lung mice with tumor life span.Buthus martensii karshi tail gavage, prevention administration group S180 sarcoma suppression ratio is 45%, and therapeutic administratp group S180 sarcoma suppression ratio is 47.6%, shows that it has preventive and therapeutic action concurrently.

Semen Strychni controls throat arthralgia pain, swollen ulcer drug, migratory arthralgia pain, fracture, facial paralysis, myasthenia gravis.1. removing obstruction in the collateral to relieve pain: by dispelling the wind and dampness pathogens insensitive impediment or contracture numbness.2, dispersing swelling and dissipating binds: with controlling wound pain caused by ecchymoma and ulcer sore pain.In recent years plant cancerous protuberance with Zhiduo County, have certain curative effect.3. treat poliomyelitis sequela, prolapse of lumbar intervertebral disc, trigeminal neuralgia, rheumatoid arthritis, traumatic injury, pain due to blood stasis, anemofrigid-damp arthralgia, general joint contracture, numbness, cancerous protuberance etc.

Radix Tripterygii Wilfordii, cry again Caulis Fibraureae, beeswax rattan, cabbageworm medicine, red medicine, water Folium illicii Lanceolati, Classification system: Tripterygiumwilfordii Hook.f. is the root of Celastraceae, tripterygium plant Radix Tripterygii Wilfordii, liana shrub, main product in Fujian, Zhejiang, Anhui, the ground such as Henan.In being born in the shade many wet hillside, mountain valley, small stream limit bushes.The hillside that happiness is comparatively shady and cool, the sand soil deep with slant acidity, soil layer or the most suitable growth of yellow soil.Bitter in the mouth, pungent, cool in nature, poison greatly.Return liver, kidney channel.Effect expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, reducing swelling and alleviating pain, removing toxic substances parasite killing.For damp and hot tuberosity, the long-pending poison of carcinoma, treat lepra reaction, rheumatoid arthritis etc. with it clinically, have the effect such as antitumor, antiinflammatory

Herba speranskiae tuberculatae, formal name used at school: Phryma leptostachyaL. has another name called distiller’s yeast grass, Staggergrass etc.Part of being used as medicine is plant herb.So that herb color is green, dry, matter is tender, free from admixture person is good.There are blood circulation promoting and blood stasis dispelling, diuresis removing toxic substances, deep effect of stimulating the menstrual flow.External application mashed by fresh grass, can control the swollen pain of furuncle, insect-bite.

Rhizoma Homalomenae formal name used at school: Homalomena occulta, English name: RHIZOMAHOMALOMENAE.Araeceae Rhizoma Homalomenae belongs to herbaceos perennial.Gas is fragrant, acrid in the mouth, micro-hardship.Property pungent, temperature.Mild toxicity.Be included into liver; Kidney; Stomach warp.There is the effects such as wind-damp dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, pain relieving, detumescence.Can dispelling the wind and dampness pathogens arthralgia pain, podomere acid is educated, muscles and bones flaccidity is soft, traumatic injury, stomachache, carbuncle skin ulcer are swollen.

Eupolyphaga Seu Steleophaga has effect of removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.Pharmacological evaluation, has the effect of dispersing swelling and dissipating binds.Cure mainly blood stasis etc. in traumatic injury, abdomen.Containing volatile oil and aminoacid.Volatile oil total amount about 22%, is mainly naphthalene, fatty aldehyde, aromatic aldehyde; Total amino acid content about 40%.Pharmacology: hematocrit, whole blood high shear viscosity, whole blood low shear viscosity, erythrocyte aggregation index, erythrocyte mechanical fragility can be made all to reduce, make erythrocyte sedimentation rate, erythrocyte sedimentation rate constant obviously raises.In addition effects such as also having blood fat reducing, anoxia enduring, ease pain, resist myocardial ischemia.Cold in nature, salty in the mouth; Slightly poisonous.Function cures mainly: removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.For injured bone, blood stasis amenorrhea, lump in the abdomen mass in the abdomen.

Radix Aconiti Preparata is pungent, bitter, heat; Very toxic.GUIXIN, liver,kidney,spleen warp.Expelling wind and removing dampness, antalgic.Have a pain for anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type.How to use after the process of preparing Chinese medicine.

Oleum Sesami is the fatty oil squeezed from Hu section plant sesame seed, and general Semen Sesami Nigrum takes, and Semen sesami Albae extracts oil.Meridian distribution of property and flavor: sweet, cool, nontoxic.Chemical composition: in Oleum Sesami, main component is unsaturated fatty acid, accounts for 85%-90%, oleic acid and linoleic acid respectively account for 50% substantially, are characterized in that stability is strong, and easily preserve, this is because containing a kind of Natural antioxidant---Semen Sesami acid in Oleum Sesami.Also containing mineral such as protein, sesamin, vitamin E, lecithin, sucrose, calcium, phosphorus, ferrum in Oleum Sesami, it is a kind of edible oil of vegetal pole horn of plenty.Effect: Chinese medicine is thought: this product nature and flavor are sweet, cool, has effect of loosening bowel to relieve constipation, removing toxic substances and promoting granulation.Record according in Compendium of Material Medica: " have moisturize, detoxify, pain relieving, detumescence merit." " not Lu " say: " sharp large intestine, afterbirth does not fall.Survivor's lump of rubbing swells, raw alopecia." clinically also decoct plaster with Oleum Sesami, there is granulation promoting meat, an effect of the pain that relieves the pain, subduing inflammation, benefit rhagades of the skin.Containing sesamin in linum, when with siritch parch or bake dish or food, the compound of sesamin and the acid of decomposable asymmetric choice net (+) Semen Sesami and some fragrance, these fragrance matters can volatilize at normal temperatures, its aromatic flavor, elegant, tempting appetite are that other similar vegetable oil all hardly match.

The preparation method of capsule of the present invention:

Get Fructus Amomi 1500g, Poria 1500g, Cortex Magnoliae Officinalis 1500g, Radix Gentianae Macrophyllae 1500g, Rhizoma Dioscoreae 1500g, Radix Dipsaci 1500g, Herba Schizonepetae 1500g, Radix Achyranthis Bidentatae 1500g, Fructus Rosae Laevigatae 1500g, Radix Angelicae Pubescentis 1500g, Herba Taxilli 1500g, Rhizoma Polygoni Cuspidati 1500g, Cortex Eucommiae 1500g, Rhizoma Cibotii 1500g, Lycopodium casuarinoides Spring 1500g, Rhizoma Drynariae 1500g, Rhizoma Chuanxiong 1500g, geranium 1500g, Radix Paeoniae Rubra 1500g, Rhizoma Corydalis 1500g, Pheretima 1500g, Fructus Psoraleae 1500g, Pericarpium Citri Reticulatae 1500g; All crude drug are cut into coarse granule, then put into ethanol, soak more than 2 hours, add respectively account for crude drug gross mass 8 times amount, 6 times amount ethanol heating extraction 2 times, extraction time is 2 hours, 1 hour; Merge 2 extracting solution, extracting solution is centrifugal by tubular type, obtains centrifugal liquid, and centrifugal liquid is crossed D101 macroporous resin and adsorbed, and first washes remove impurity with water, then carries out eluting with the ethanol of 70%, collects eluent, concentrating under reduced pressure, one-tenth extractum, as component 1, and stand for standby use.Again the medicinal residues that above-mentioned ethanol extraction is crossed are added water heating 1 ~ 2 hours reflux accounting for its quality 10 times amount and extract 2 times; Extraction time is 2 hours, 1 hour; Merge 2 extracting solution, extracting solution is centrifugal by tubular type, obtains centrifugal liquid, and centrifugal liquid is crossed D 101 macroporous resin and adsorbed, and first washes remove impurity with water, then carries out eluting with the ethanol of 70%, collects eluent, concentrating under reduced pressure, becomes extractum standing, for subsequent use as component 2.Above-mentioned two kinds of component extractum are merged, when concentrating under reduced pressure relative density is 80 DEG C 1.28 pasty state, reclaim ethanol, gained pasty state is passed into spray dryer and carries out spraying dry, the compressed air pressure crossing spray dryer shower nozzle is 4kg/m2, hothouse hot stream temperature is 80 DEG C, obtains crude drug medicated powder; Incapsulate after ultraviolet sterilization.

The preparation method of the present invention's honey refining pill:

Get Fructus Amomi 1200g, Poria 1100g, Cortex Magnoliae Officinalis 1200g, Radix Gentianae Macrophyllae 1100g, Rhizoma Dioscoreae 1100g, Radix Dipsaci 1100g, Herba Schizonepetae 1200g, Radix Achyranthis Bidentatae 1100g, Fructus Rosae Laevigatae 1200g, Radix Angelicae Pubescentis 1200g, Herba Taxilli 1200g, Rhizoma Polygoni Cuspidati 1100g, Cortex Eucommiae 1100g, Rhizoma Cibotii 1200g, Lycopodium casuarinoides Spring 1100g, Rhizoma Drynariae 1200g, Rhizoma Chuanxiong 1200g, geranium 1100g, Radix Paeoniae Rubra 1200g, Rhizoma Corydalis 1200g, Pheretima 1200g, Fructus Psoraleae 1200g, Pericarpium Citri Reticulatae 1200g; Soak 30 minutes to 1 hour, heating boils 30 ~ 40 minutes, and filter, filtrate is for subsequent use; The second time that adds water filtering residue heats, and boils 20 ~ 30 minutes, filters; Three filtrates be combined, heating is concentrated into pasty state, and after putting into the oven dry of 80 DEG C, baking oven, pulverizing and Mel are in harmonious proportion and are twisted into pill.

The preparation of Tablets:

Get Fructus Amomi 1200g, Poria 1100g, Cortex Magnoliae Officinalis 1200g, Radix Gentianae Macrophyllae 1100g, Rhizoma Dioscoreae 1300g, Radix Dipsaci 1100g, Herba Schizonepetae 1200g, Radix Achyranthis Bidentatae 1100g, Fructus Rosae Laevigatae 1200g, Radix Angelicae Pubescentis 1200g, Herba Taxilli 1200g, Rhizoma Polygoni Cuspidati 1100g, Cortex Eucommiae 1100g, Rhizoma Cibotii 1200g, Lycopodium casuarinoides Spring 1300g, Rhizoma Drynariae 1200g, Rhizoma Chuanxiong 1200g, geranium 1300g, Radix Paeoniae Rubra 1200g, Rhizoma Corydalis 1200g, Pheretima 1200g, Fructus Psoraleae 1200g, Pericarpium Citri Reticulatae 1200g; First all crude drug are cut into coarse granule, then put into ethanol, soak more than 2 hours, add respectively account for crude drug gross mass 8 times amount, 6 times amount ethanol heating extraction 2 times, extraction time is 2 hours, 1 hour; Merge 2 extracting solution, extracting solution is centrifugal by tubular type, obtains centrifugal liquid, and centrifugal liquid is crossed D 101 macroporous resin and adsorbed, and first washes remove impurity with water, then carries out eluting with the ethanol of 70%, collects eluent, concentrating under reduced pressure, one-tenth extractum, as component 1, and stand for standby use.Again the medicinal residues that above-mentioned ethanol extraction is crossed are added water heating 1 ~ 2 hours reflux accounting for its quality 10 times amount and extract 2 times; Extraction time is 2 hours, 1 hour; Merge 2 extracting solution, extracting solution is centrifugal by tubular type, obtains centrifugal liquid, and centrifugal liquid is crossed D 101 macroporous resin and adsorbed, and first washes remove impurity with water, then carries out eluting with the ethanol of 70%, collects eluent, concentrating under reduced pressure, becomes extractum standing, for subsequent use as component 2.Above-mentioned two kinds of component extractum are merged, when concentrating under reduced pressure relative density is 80 DEG C 1.28 pasty state, reclaim ethanol, gained pasty state is passed into spray dryer and carries out spraying dry, the compressed air pressure crossing spray dryer shower nozzle is 4kg/m2, hothouse hot stream temperature is 80 DEG C, obtains crude drug medicated powder, adds starch tabletting.

The preparation of medicinal external emulsifiable paste agent of the present invention:

First Radix Clematidis 1500g, Sanguis Draxonis 1500g, Olibanum 1500g, Ramulus Cinnamomi 1500g and the Rhizoma Homalomenae 1500g way of distillation are vaporized into crystallization, pulverize for subsequent use; By all the other crude drug medicine Radix Dipsacis 1500g, Flos Carthami 1500g, Radix Tripterygii Wilfordii 1500g, Radix Aconiti Preparata 1500g, Eupolyphaga Seu Steleophaga 1500g, Herba speranskiae tuberculatae 1500g, Rhizoma Polygoni Cuspidati 1500g, Semen Strychni 1500g, Radix Angelicae Dahuricae 1500g, add and account for its quality 5 ~ 8 times amount alcohol heating reflux and extract 2 times, described each 1 ~ 2 hour, 2 extracting solution are merged and leaves standstill; In described step c, the medicinal residues that above-mentioned ethanol extraction is crossed are added 5 ~ 8 times of water gaging heating and refluxing extraction 2 times, each 1 ~ 2 hour, 2 extracting solution are merged and leaves standstill; The medicinal residues that above-mentioned ethanol extraction is crossed are added water heating 1 ~ 2 hours reflux accounting for its quality 10 times amount and extract 2 times; Extraction time is 2 hours, 1 hour; Merge 2 extracting solution, extracting solution is centrifugal by tubular type, obtains centrifugal liquid, and centrifugal liquid is crossed D 101 macroporous resin and adsorbed, and first washes remove impurity with water, then carries out eluting with the ethanol of 70%, collects eluent, one-tenth extractum stand for standby use; In described steps d, above-mentioned 2 kinds of extracting solution are merged, when concentrating under reduced pressure relative density is 80 DEG C 1.35 filtrate, reclaim ethanol, by gained filtrate adjustment proportion to 1.50, reduce pressure to obtain extractum, adds the crystalline powder prepared, and the glycerol that is in harmonious proportion stirs furnishing emulsifiable paste.

The preparation of emplastrum of the present invention: first Radix Clematidis 1500g, Sanguis Draxonis 1500g, Olibanum 1500g, Ramulus Cinnamomi 1500g and the Rhizoma Homalomenae 1500g way of distillation are vaporized into crystallization, pulverize for subsequent use; By all the other crude drug medicine Radix Dipsacis 1500g, Flos Carthami 1500g, Radix Tripterygii Wilfordii 1500g, Radix Aconiti Preparata 1500g, Eupolyphaga Seu Steleophaga 1500g, Herba speranskiae tuberculatae 1500g, Rhizoma Polygoni Cuspidati 1500g, Semen Strychni 1500g, Radix Angelicae Dahuricae 1500g, put into ethanol heating and refluxing extraction 2 times; Each 1 ~ 2 hour, extracting solution is left standstill.The crude drug medical material crossed by ethanol extraction adds water heating and refluxing extraction 1 time, each 1 ~ 2 hour; Then 2 kinds of extracting solution are merged and leave standstill.Merged by above-mentioned two kinds of extracting solution, will merge in the extracting solution suction concentrating under reduced pressure tank of latter 2 times, be decompressed to 0.03-0.08MPa, temperature remains on 60-80 DEG C, and being concentrated into relative density is 1.20, the extractum of temperature to 60 DEG C-70 DEG C; Three filtrates be combined, heating is concentrated into pasty state, the distillation crystalline powder of mediation preparation, is in harmonious proportion and spreads on the joint that swells and ache, paste medicine part, need clean, fix with preservative film, medical adhesive tape with wine, vinegar, Mel.Can tolerate as degree with patient, take off after general 5h, every day 1 time.

The preparation of plaster of the present invention:

First Radix Clematidis 1500g, Sanguis Draxonis 1500g, Olibanum 1500g, Ramulus Cinnamomi 1500g and the Rhizoma Homalomenae 1500g way of distillation are vaporized into crystallization, pulverize for subsequent use; By all the other crude drug medicine Radix Dipsacis 1500g, Flos Carthami 1500g, Radix Tripterygii Wilfordii 1500g, Radix Aconiti Preparata 1500g, Eupolyphaga Seu Steleophaga 1500g, Herba speranskiae tuberculatae 1500g, Rhizoma Polygoni Cuspidati 1500g, Semen Strychni 1500g, Radix Angelicae Dahuricae 1500g, the crude drug medical material of above-mentioned parts by weight adds in the Oleum Sesami accounting for its 5-10 times weight portion and soaks 3-5 days, heating extraction, first big fire is boiled, and after Oleum Sesami boiling, firepower reduces, enduring to pharmaceutical presentations is dark brown, and inner coke yellow, pulls medicinal residues out, continued to temper by medicine oil, and constantly stir, refining is to the beading that drips; Again Plumbum preparatium is fried to vermilion, removing moisture, cross 100 mesh sieve removing impurity; Plumbum preparatium is slowly added in the medicine oil refined, constantly stir, become the thick paste of black, again the crystallization of pulverizing is stirred in the slightly cold rear impouring cold water of the plaster refined, soak 5-10 days, change water every day once, releasing fire-toxin, then put the crystalline particle of pulverizing into mastic, stir.

Toxicology test:

Test example 1: acute toxicity test of the present invention

One, test material:

Animal: Kunming mouse, body weight 21-24g, male and female half and half, Shandong University's biology laboratory breeding.Medicine: Tablets, containing 0.0365g crude drug/sheet

Two, method:

1, LD50 calculates: adopt improvement karber's method, mice is divided into 5 groups at random, often organize 10, male and female half and half, dissolve tablet adding distil water, are made into Cmax, by the administration of mice maximum permission capacity, institute is followed successively by 18,14.4 to dosage by crude drug amount, 11.5,9.2,7.4 (g.kg-1), in animal fasting (can't help water) after 18 hours, administration at twice in one day (interval half an hour), each 0.5ml, observes animal dead situation.

2, maximum tolerated dose measures (MTD value): get mice 20, each 10 of male and female.Tablet adding distil water is dissolved, is made into maximum concentration, by the maximum tolerated dose of animal, feed device and can twitch to inject to fill with and be as the criterion.In animal fasting (can't help water) after 18 hours, administration at twice in one day (interval half an hour), each 0.5ml (every ml containing crude drug 0.36g), total dose is 18g crude drug/kg.d, 300 times of quite clinical adult 50Kg body weight consumption.Continuous Observation 7 days after administration.

Three, result of the test:

In LD50 calculates when giving mice with maximum acceptable concentration and maximum permission capacity (18g/Kg.d), have no dead mouse, namely LD50 is not measured, ask maximum tolerated dose only, in 7 day observation period, its appetite of animal, activity, hair color, the mental status etc. are all normal, grow normal, there are no death.Namely select the 300 times of doses being equivalent to clinical dosage, and have no adverse reaction, show that acute toxicity is minimum, MTD > 18g/Kg.d.

Experimental example 2: aggregate toxicity is tested:

The agent of Chinese medicine preparation of the present invention honey refining for oral administration pill presses 7.69,19.18 and 43.21g crude drug/kg continuous use 15 weeks (1.0ml/100g body weight to mice, every day 2 times) and drug withdrawal after 3 weeks, result shows: the index such as hair, behavior, defecation, body weight, organ weights, hemogram, hepatic and renal function, blood glucose, blood fat of Chinese medicine preparation of the present invention to rat all has no significant effect, internal organs naked eyes do not find that difference change and histological indications show, medication 15 weeks and drug withdrawal are after 3 weeks, and each internal organs of rat are all without obviously changing.Illustrate that Chinese medicine preparation oral capsule of the present invention is little to toxicity after rat long-term prescription, also there is no difference reaction after drug withdrawal, application safety.

Experimental example 3: acute dermal toxicity result of the test

Medicine externally used compound preparation of the present invention, has expelling wind and removing dampness, and effect of promoting blood circulation to remove obstruction in the collateral is used for the treatment of the disease such as rheumatism, rheumatoid arthritis.Accordingly, first carry out acute dermal toxicity test, to observe this medicine to the nontoxic level in the whether true border of rat acute percutaneous toxicity.

Tested material: the preparation ointment of external of the present invention.Weighing tested material 50g adding distil water, to make 50% pastel for subsequent use.

Laboratory animal: provide SD rat 20 by Medicine Institute, Shandong Province Experimental Animal Center, male and female half and half, body weight 180-220g, primary animal (dynamic No. 08-25th, the word of doctor), feed resource is the same.Animal housing's environment: temperature: 22-25 DEG C, relative humidity: 45-55%, the Animal House quality certification number: dynamic No. 08-37th, the word of doctor.Test method: test first 24 hours, in back part of animal spinal column both sides unhairing, unhairing scope is about body surface area 10%.By the dosage (coating amount 1.0g/100g.bw) of 5000mg/kg.bw, examination Mus unhairing position is applied and fixed, after 24 hours, the residual tested material of warm water removing, Continuous Observation 7 days.Result of the test: have no examination Mus whole body ANOMALOUS VARIATIONS in the observation period, also have no dead, is coated with the reactions such as tested material local has no red and swollen, festers, inflammation, necrosis.These results suggest that this medicine is to the nontoxic level in the true border of rat acute percutaneous toxicity.

Experimental example 4: repeatedly Skin Irritation Test result

According to the requirement of DB61-267-1998 " health product Toxicological evaluation program and the method for inspection ", repeatedly Skin Irritation Test is carried out to medicine of the present invention.

Tested material: liniment of the present invention.Weighing tested material 50g adding distil water, to make 50% pastel for subsequent use.

Laboratory animal: provide Japanese white big ear rabbit 4 by Shandong University's medical college Experimental Animal Center, male and female half and half, body weight 2.5-3.0kg, primary animal (dynamic No. 08-018th, the word of doctor), feed resource is the same.Animal housing's environment: temperature: 22-25 DEG C, relative humidity: 45-55%.The Animal House quality certification number: dynamic No. 08-37th, the word of doctor.Test method: test first 24 hours, in every rabbit back spinal column both sides cropping preserved skin, each 3cm × 6cm of unhairing scope.Only get tested material 0.5g/, be coated in after preparation on the skin of every rabbit side, smear every day once, offside all makes solvent control.Smear 14d continuously.Cropping before being coated with every day, must not injured skin, ensures that tested material fully contacts with skin.Observe dermoreaction and marking every day.Off-test, gets and smears area skin and carry out histopathologic examination.

Experimental result: repeatedly Skin Irritation Test shows that repeatedly the highest stimulation index of skin irritation and pathological tissue integration are 0 in the present invention, according to skin irritation strength grading standard in DB61-267-1998 " health product Toxicological evaluation program and the method for inspection ", the present invention repeatedly skin irritation intensity belongs to nonirritant.

Experimental example 5, skin anaphylactic test

According to the requirement of DB61-267-1998 " health product Toxicological evaluation program and the method for inspection ", skin anaphylactic test is carried out to medicine of the present invention.

Tested material: liniment of the present invention.Weighing tested material 10g adding distil water, to make 50% pastel for subsequent use.Positive control: 2,4-dinitro-chloro-benzene, produce in Xing Jin chemical plant, Beijing, lot number 20020522.Laboratory animal: provide Cavia porcellus 30 by Shandong University's medical college Experimental Animal Center, male and female half and half, body weight 250-300g, primary animal, feed resource is the same.Animal housing's environment: temperature: 22-25 DEG C, relative humidity: 45-55%.The Animal House quality certification number: dynamic No. 08-37th, the word of doctor.Test method: test Cavia porcellus is divided into three groups at random, often organize 10, male and female half and half, are respectively tested material group, negative control group and positive controls.

Sensitization contact: removed by guinea pig back left of spine hair for first 24 hours to tested material, unhairing scope is about 3cm × 3cm.Get tested material 0.2g/ only, be coated in district of losing hair or feathers on the left of back part of animal after preparation, continue 6 hours.7th day and fortnight, repeat once with same method, and positive controls is coated with 1%DNCB, and negative control group does not deal with.Excite contact: fortnight after last is to tested material, by tested material 0.2g/ only, be coated on district of losing hair or feathers on the right side of guinea pig back after preparation, remove tested material after 6 hours, at once observe anaphylaxis situation, then again observed in 1,24,48,72 hour.Positive controls is coated with 1%DNCB, and negative control group does not deal with.Observational technique is with tested material group.

Result of the test: skin anaphylactic test shows patch of the present invention, according to according to sensitization of skin intensity evaluation standard relevant in DB61-267-1998 " health product Toxicological evaluation program and the method for inspection ", the invention belongs to without sensitization.

Experimental example 6, anti-inflammation test, analgesic test, microcirculation test

Anti-inflammation test: tested group of mouse ear inflammation swelling is less than blank group, and difference has significance (P<0.05), illustrates that patch of the present invention has certain antiinflammatory action.Analgesic test: tested group of mouse writhing number of times reduces than blank group, and difference has significance (P<0.05).Illustrate that patch of the present invention has certain analgesic activity.

Microcirculation test: tested group of Mice Auricle fine motion, vein bore and capillary vessel number all comparatively blank group obviously increase, and difference all has highly significant (P<0.01), illustrate that patch of the present invention has and improve the microcirculatory effect of Mice Auricle.

Pharmacological experiment illustrates:

Pharmacological experiment

The compound preparation that oral medicine of the present invention is made up of Chinese crude drugs such as Rhizoma Cibotii, Radix Polygoni Multiflori Preparata, the Cortex Eucommiae, Herba Taxilli, Rhizoma Corydalis, Flos Carthami, Radix Achyranthis Bidentataes, has the effect of liver and kidney tonifying, activating blood circulation to dissipate blood stasis, removing obstruction in the collateral to relieve pain.The lumbago and skelalgia that to cure mainly that caused by liver and kidney deficiency, QI-blood circulation are smooth, blood stasis is stagnated, venation is obstructed etc. caused, and the effect of lumbar muscle strain, and with YAOTONGNING (take), unblocking collaterals to treat arthritis subsides (external) compares

1, instrument and material

GSH-II type operating loupe (Tianjin medical optical instrument factory), the full-automatic blood flow of FASCO-3010A accelerates and surveys instrument (Weiduo Bioengineering Institute of Chongqing University).YAOTONGNING (Chengde Chinese medicine Group Co., Ltd, lot number: 040119).W istar rat, white big ear rabbit, male and female dual-purpose, is purchased from Chinese Medical Sciences University's Experimental Animal Center, production licence number: SCXK2003-0009.Unblocking collaterals to treat arthritis pastes, and is to be produced by Jilin Wan Tong Pharmaceutical group, Ji Weijian No. 024th, word (2006).Alleviate the pain that femur head necrosis, hyperosteogeny, cervical spondylosis, lumbar spondylosis, intervertebral disk hernia, rheumatic arthritis, ankylosing spondylitis, scapulohumeral periarthritis, traumatic injury, Senile osteoarthritis etc. cause, promote its rehabilitation.Suitable population: be applicable to because of rheumatism, rheumatoid arthritis, scapulohumeral periarthritis, cervical spondylosis, lumbar muscle strain, hyperosteogeny, traumatic injury, the pain that prolapse of lumbar intervertebral disc etc. cause and lumbago and skelalgia, sciatica

2, method

2,1 the present invention is to the effect of rabbit lumbar muscle strain

Get the sodium sulfide depilation that healthy white big ear rabbit mass fraction is 10%, after pentobarbital sodium 30mg/kg-1 anaesthetizes, under sterile working, centered by crista iliaca to ischial tuberosity line mid point spinous process side 0,5cm place, cut skin, subcutaneous tissue along spinous process direction, the sacral nerves of walking out intervertebral foramina can be seen in the dark face of open center, be then 2 by quality, 5mg, diameter is that the circular filter paper sheet of 5mm is put in nerve root armpit, successively.Sew up, sterile dressing.Rabbit 80 of being paralysed by Post operation is divided into 5 groups at random, and often organize 16, postoperative 3d starts administration, is respectively excipient control group, skin paste excipient; The high, medium and low dosage group of the present invention, skin adhesive plaster, takes off after sticking 6h every day; Positive control drug YAOTONGNING group, SHEXIANG ZHUANGGU GAO group, gastric infusion; Administration every day 1 time, successive administration 30d.Each treated animal respectively at postoperative 1st, 7,14,21,28d observed and recorded rabbit model activity sign: gait, the threshold of pain, sense of touch situation; Each group respectively after surgery the 5th, 15,25d randomly draws 2 mould rabbits and puts to death, and causes while scorching stimulus object weighs, and gets its sacral nerve roots and surrounding tissue does pathological examination.After administration 30d, the blood sampling of each group Rabbit Heart measures hemorheology index.Put to death simultaneously, open operative site and fiber enclosed mass, measure filter paper quality, and get its sacral nerve roots and surrounding tissue does histopathologic examination, separately get normal rabbits 10, get its sacral nerve roots and surrounding tissue does histopathologic examination simultaneously.Gait: the degree that the paralysis of mould rabbit suffering limb recovers, criterion is as follows, panplegia: complete paralysis, and muscle ungauged regions, joint position does not change.Semi-paralysis: limbs can piecemeal activity, walking is walked lamely.Recover: very nearly the same with normal walking movement, tractive both sides lower-limb muscular strength is close.

The threshold of pain: with acupuncture mould rabbit toes to judge pain sensation recovery extent, criterion is as follows, responsive: acupuncture mould rabbit toes, and lower limb twitch retraction, later visits.Insensitive: acupuncture mould rabbit toes are reactionless, even stick a needle into skin also reactionless.Sense of touch: touch rabbit toes with dry cotton-wool, the difference of contrast Ipsilateral hind leg tactile sensing.Responsive: touch rabbit toes and respond, suffering limb is twitched.Insensitive: touch rabbit toes reactionless, suffering limb is without twitch.

2,2 the present invention are to the anti-inflammatory analgetic effect of In Rat Lumbar muscular strain model

Get the sodium sulfide depilation that healthy W istar rat mass fraction is 10%, after urethane 1,2g/kg-1 anesthesia, under sterile working, centered by L4-5 interspinal interstice, be about 4cm at back median incision, cut skin, subcutaneous tissue.Blunt separation waist paravertebral muscles, self-retractor retracts, and stings except L4-5 spinous process, right side vertebral plate and articular process, fully cauda equina nerve and right side L5 nerve root is exposed under operating loupe, the silica gel piece of about 25mg is placed in the armpit that right side L5 nerve root goes out dural sac, wrapping is fixing, layer-by-layer suture.Operation modeling success rat 50 is divided into 5 groups at random, often group 10, model control group, the present invention is for oral administration, the high, medium and low dosage group of externally used paste, and positive control drug YAOTONGNING group, unblocking collaterals to treat arthritis subsides group, separately get 10 rats and make blank group.The postoperative 3d of each treated animal starts administration, administration every day 1 time, successive administration 30d.After last administration terminates, get local organization around nerve root, prepare tissue homogenate, centrifuging and taking supernatant, measure PGE2 and Assay of histamine levels.

2,3 statistical procedures

Enumeration data X 2 test, measurement data data represent with (-x ±-s), and between group, group difference is compared in t inspection.

3, experimental result

3,1 apophysis spirit cream recovers the comparison of number of cases and positive rate to panplegia mould rabbit

Gait: postoperative 1st day of modeling, each treated animal is all in panplegia state.From the 1st day to the 7th day, the ratio of semi-paralysis is returned to by panplegia, of the present invention group and YAOTONGNING group compare there was no significant difference (P>0,05) with matched group, from the 7th day to the 28th day, by semi-paralysis to each administration group of ratio recovered and matched group comparing difference significantly (P<0,05, P<0,01), in table 1.

The threshold of pain: postoperative 1st day, the reaction of the mould rabbit pain sensation is feminine gender, and from the 7th day to the 28th day, cream group was taken in the present invention orally and the YAOTONGNING group threshold of pain is obviously better than matched group (P<0,05, P<0,01), in table 2.

Table 2 mould rabbit analgesic activity result of the test (± S, n=10)

Note: compare * P<0.05 with Matrix controls group, * * P<0.01

Sense of touch: postoperative 1st day, mould rabbit tactile response was feminine gender, from the 7th day to the 28th day, external plaster group of the present invention and the sense of touch of unblocking collaterals to treat arthritis subsides group obviously than matched group sensitivity (P<0,05), in table 3.

Table 3 mould rabbit tactile response result of the test (± S, n=10)

Note: compare * P<0.05 with Matrix controls group, * * P<0.01

Perusal nasal mucosa change after mice is put to death in cervical vertebra fracture, comprises nasal mucosa color and luster, with or without hyperemia, edema, hemorrhage, ulcer etc. and each organ of mice is with or without obvious change.Each administration group be significantly increased panplegia rabbit 14,21,28d time recover positive rate, with matched group comparing difference significantly (P<0,05, P<0,01).Show that the recovery of externally used paste of the present invention to the motion of mould rabbit suffering limb, the pain sensation, sense of touch has obvious facilitation.

Clinical treatment:

Lumbar muscle strain is generally attributed to the traditional Chinese medical science " lumbago " " arthromyodynia " category, and it is because of not outer two ends: one because of interior-deficiency, and one because of exterior-excess.Traditional Chinese medical science lumbar muscle strain is clinical common, mostly can alleviate or cure through expectant treatment.A few symptoms severe patient needs operation.The author for this disease of main treatment, obtains effect excellent with oral medicinal herb external application.In long-term clinic diagnosis, sum up dispelling cold by warming the meridian, blood circulation promoting and blood stasis dispelling, eliminating phlegm dredging collateral, be good for the method that kidney strengthens waist.

1 cause of disease: lumbar muscle strain is generally attributed to the traditional Chinese medical science " lumbago " " arthromyodynia " category, and it is because of not outer two ends: one because of interior-deficiency, and one because of exterior-excess.Waist is house of kidney, and void then spinal column is lost foster, aching and limp unable, and its pain is continuous, and actually refer to that wind-cold damp pathogen gas is invaded outward, coagulation of QI-blood, forms numbness for a long time.Face card visible: most of patients has chronic back pain history, recurrent exerbation, time light time weight, acute exacerbation after suffering from cold of getting involved, leads and lower limb more.Some patients has waist wound, sprains history, leaves over and causes harm, and gradually weighs and sends out.In general, damp of having a cold outward must have deficiency in origin formerly, only has interior-deficiency, could be subject to evil and not go, keeping and cause harm.So interior-asthenia and exterior-sthenia is many and see, always with obstruction of meridians and collaterals, stagnation of QI and blood may bring about pain.

Modern medicine thinks that this disease is the result that a variety of causes causes a disc degradation, and it produces clinical symptoms has mechanicalness and chemical factor to the impact of nerve.But certainly the weight of clinical symptoms is not directly proportional with outstanding degree, and inflammatory reaction plays an important role in the morbidity of disc herniation.This inflammatory reaction is similar to traditional Chinese medical science expectorant and coagulates, and belongs to the category of insubstantial phlegm.

2 determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs

According to its because of, draw other people experience, draft dispelling cold by warming the meridian, method that blood circulation promoting and blood stasis dispelling, strong kidney strengthen waist, eliminating phlegm dredging collateral.Prescription: Fructus Amomi 10 ~ 20 parts, 10 ~ 20 parts, Poria, Cortex Magnoliae Officinalis 10 ~ 20 parts, Radix Gentianae Macrophyllae 10 ~ 20 parts, Rhizoma Dioscoreae 10 ~ 20 parts, Radix Dipsaci 10 ~ 20 parts, Herba Schizonepetae 10 ~ 20 parts, Radix Achyranthis Bidentatae 10 ~ 20 parts, Fructus Rosae Laevigatae 10 ~ 20 parts, Radix Angelicae Pubescentis 10 ~ 20 parts, Herba Taxilli 10 ~ 20 parts, Rhizoma Polygoni Cuspidati 10 ~ 20 parts, the Cortex Eucommiae 10 ~ 20 parts, Rhizoma Cibotii 10 ~ 20 parts, Lycopodium casuarinoides Spring 10 ~ 20 parts, Rhizoma Drynariae 10 ~ 20 parts, Rhizoma Chuanxiong 10 ~ 20 parts, geranium 10 ~ 20 parts, Radix Paeoniae Rubra 10 ~ 20 parts, Rhizoma Corydalis 10 ~ 20 parts, Pheretima 10 ~ 20 parts, Fructus Psoraleae 10 ~ 20 parts, Pericarpium Citri Reticulatae 10 ~ 20 parts; In external used medicine: Olibanum 10 ~ 20 parts, Sanguis Draxonis 10 ~ 20 parts, Radix Dipsaci 10 ~ 20 parts, Radix Clematidis 10 ~ 20 parts, 10 ~ 20 parts, Flos Carthami, Rhizoma Homalomenae 10 ~ 20 parts, Radix Tripterygii Wilfordii 10 ~ 20 parts, Ramulus Cinnamomi 10 ~ 20 parts, Radix Aconiti Preparata 10 ~ 20 parts, Scorpio 10 ~ 20 parts, Herba speranskiae tuberculatae 10 ~ 20 parts, Rhizoma Polygoni Cuspidati 10 ~ 20 parts, Semen Strychni 10 ~ 20 parts, Eupolyphaga Seu Steleophaga 10 ~ 20 parts, the Radix Angelicae Dahuricae 10 ~ 20 parts.

3 model cases

Patient's first, man, 47 years old, first visit on February 5 in 2012, electronic prescription number: 3983.Lifted weight before about two years and sprain waist, lead and thigh discomfort, transference cure after simple treatment of having a rest, leaves over chronic problem, heavy when time is light, heavy then feel that thigh sinks to right lower extremity acid, instep and hallux toe place picotement, about increased the weight of suddenly before January, waist buttocks and legs pain is abnormal, walks unfavorable.Through traction and transfusion oral drugs without alleviation.City Hospitals thinks outstanding comparatively large, and obviously, excision of advocating, examines because fearing operation in compressing.Straight-leg raising test is positive, and waist 4,5 hole place tenderness are not obvious, considers that intraspinal tube factor is large.Diet can, large dry stool, lower limb has cool feeling, the white greasy deep-rolling pulse of the slightly fat tongue of dimly red tongue.Examine as deficiency of both the liver and kidney, cold-phlegm stagnates, and asthenia of both the spleen and kidney, QI and blood are obstructed.Prescription: Fructus Amomi 12g, Poria 13g, Cortex Magnoliae Officinalis 13g, Radix Gentianae Macrophyllae 13g, Rhizoma Dioscoreae 12g, Radix Dipsaci 13g, Herba Schizonepetae 12g, Radix Achyranthis Bidentatae 13g, Fructus Rosae Laevigatae 12g, Radix Angelicae Pubescentis 13g, Herba Taxilli 13g, Rhizoma Polygoni Cuspidati 13g, Cortex Eucommiae 11g, Rhizoma Cibotii 13g, Lycopodium casuarinoides Spring 12g, Rhizoma Drynariae 12g, Rhizoma Chuanxiong 13g, geranium 13g, Radix Paeoniae Rubra 12g, Rhizoma Corydalis 13g, Pheretima 13g, Fructus Psoraleae 13g, Pericarpium Citri Reticulatae 13g; In external used medicine: Olibanum 13g, Sanguis Draxonis 12g, Radix Dipsaci 14g, Radix Clematidis 13g, Flos Carthami 13g, Rhizoma Homalomenae 13g, Radix Tripterygii Wilfordii 13g, Ramulus Cinnamomi 14g, Radix Aconiti Preparata 12g, Scorpio 13g, Herba speranskiae tuberculatae 12g, Rhizoma Polygoni Cuspidati 13g, Semen Strychni 13g, Eupolyphaga Seu Steleophaga 14g, Radix Angelicae Dahuricae 12g, after using 10 doses, pain subtracts greatly, and after following the service January, pain disappears, and occasionally has toe instep numb, after follow up a case by regular visits to July, numbness without, be still engaged in repair work.Not fatigue is advised to suffer from cold, waist functional exercise.

Patient's second, female, 52 years old.First visit on March 10 in 2012.Electronic prescription number: 4149.More than 10 years of pain history.First quarter moon cause is bowed case work for a long time, and lumbago increases the weight of, lead and left lower extremity to heel pain, can not put down sleeping, difficulty in walking.CT shows that waist 5 sacrum 1 intercalated disc is given prominence to, and seeks medical advice without alleviation through externally applied plaster transfusion oral drugs symptom.Diet two just still can, it is white thick greasy to look into dark tongue quality ecchymosis tongue.Examine as asthenia of both the spleen and kidney loss, the wet condensation of cold-phlegm, QI and blood is obstructed.Prescription: Fructus Amomi 12g, Poria 13g, Cortex Magnoliae Officinalis 13g, Radix Gentianae Macrophyllae 13g, Rhizoma Dioscoreae 12g, Radix Dipsaci 13g, Herba Schizonepetae 12g, Radix Achyranthis Bidentatae 13g, Fructus Rosae Laevigatae 12g, Radix Angelicae Pubescentis 13g, Herba Taxilli 13g, Rhizoma Polygoni Cuspidati 13g, Cortex Eucommiae 11g, Rhizoma Cibotii 13g, Lycopodium casuarinoides Spring 12g, Rhizoma Drynariae 12g, Rhizoma Chuanxiong 13g, geranium 13g, Radix Paeoniae Rubra 12g, Rhizoma Corydalis 13g, Pheretima 13g, Fructus Psoraleae 13g, Pericarpium Citri Reticulatae 13g; In external used medicine: Olibanum 13g, Sanguis Draxonis 12g, Radix Dipsaci 14g, Radix Clematidis 13g, Flos Carthami 13g, Rhizoma Homalomenae 13g, Radix Tripterygii Wilfordii 13g, Ramulus Cinnamomi 14g, Radix Aconiti Preparata 12g, Scorpio 13g, Herba speranskiae tuberculatae 12g, Rhizoma Polygoni Cuspidati 13g, Semen Strychni 13g, Eupolyphaga Seu Steleophaga 14g, Radix Angelicae Dahuricae 12g, can putting down after 5 doses crouches stretches lower limb, and after first quarter moon, pain disappears, and consolidates 5 doses.Slight discomfort is had, normal Working Life with square waist is so far even.

4 therapy experience

Lumbar muscle strain take pain numbness as primary symptom, TCM knowledge pain, and to tremble with fear as main cause, " Plain Questions numbness opinion " is said: pain person, and cold is also many, has cold event pain also." Plain Questions lift pain opinion " is said: cold enters through and checks late, tears and not all right, visitor in the outer then insufficiency of blood of arteries and veins, visitor's then flow of QI being obstructed in arteries and veins, therefore soldier but pain.Visit clinical neck, waist and leg pain patient all over, rarely have not to tremble with fear as main cause person, send out because of cold, meet cold and weigh.So more will see the person that is subject to exopathogen, positive QI-insufficiency also." in healthy energy deposits, heresy can not be done " so the loss of Liver and kidney also will be paid attention to, only have Liver and kidney to fill, could not be tired, not invade by heresy.On basis in clear and definite one outside one, take into account phlegm-damp, blood stasis, it is pathological product, become again induced pain because of, vicious cycle.For stupid difficult pain fiber crops, little dose is tantamount to take totally ineffective measures.Sometimes escalated dose just can receive effect.Radix Aconiti, Radix Paeoniae Rubra, breast does not have, and Herba Lycopodii controls the numb proved recipe of pain, Rhizoma Arisaematis, and the heavy dose of pain relieving of Radix Angelicae Pubescentis is also subject to pushing away haunt and plague.Add heavy prescription tonifying liver and kidney and strengthening bones and muscles, Pheretima, it is strong that Scorpio walks to alter power, Sou Tiluo road, conjunction for lumbar muscle degeneration, suit etiology and pathogenesis, determined curative effect, as the method for expectant treatment, can select.

Chronic lumbar muscle strain is a kind of eliminating lumbar vertebra pathological changes and serious internal organs organic disease, and with a kind of commonly encountered diseases that lumbar soft tissue pain is cardinal symptom.This disease, objective determination often can not find any positive sign, but patient's very suffering.General all having i.e. tired, the sitting i.e. pain of slightly standing, phenomenon that slightly slow, the fatigue of having a rest increases the weight of.Lumbar muscle strain, be common a kind of disease, wherein, physical labourer proportion is maximum.This disease when viscera function low (deficiency syndrome) or imbalance, causes because long-term posture is bad or overworked often again.

Waist is kidney mansion, spleen governing muscles, asthenia of both the spleen and kidney, and be bound to waist soreness.Treat this disease and to suffer from a deficiency of the kidney, therefore the kidney invigorating emphatically must be treated, take into account and control spleen.Intermittently, Radix Achyranthis Bidentatae all belongs to the medicine that fills blood, and all benefits to spleen kidney.And temper one is prosperous, kidney qi must be filled, then waist strengthens flesh by force, and lumbago is aching and limp from removing ear.Except except taking medicine, suitably doing some waist movements and take exercise, is also very important auxiliary treatment measure.

Claims

1. treat the Chinese medicine composition of spleen kidney both deficiency type lumbar muscle strain for one kind, it is characterized in that, be made up of endo-medicine and external used medicine, described endo-medicine comprises the crude drug of following weight portion: Fructus Amomi 10 ~ 20 parts, 10 ~ 20 parts, Poria, Cortex Magnoliae Officinalis 10 ~ 20 parts, Radix Gentianae Macrophyllae 10 ~ 20 parts, Rhizoma Dioscoreae 10 ~ 20 parts, Radix Dipsaci 10 ~ 20 parts, Herba Schizonepetae 10 ~ 20 parts, Radix Achyranthis Bidentatae 10 ~ 20 parts, Fructus Rosae Laevigatae 10 ~ 20 parts, Radix Angelicae Pubescentis 10 ~ 20 parts, Herba Taxilli 10 ~ 20 parts, Rhizoma Polygoni Cuspidati 10 ~ 20 parts, the Cortex Eucommiae 10 ~ 20 parts, Rhizoma Cibotii 10 ~ 20 parts, Lycopodium casuarinoides Spring 10 ~ 20 parts, Rhizoma Drynariae 10 ~ 20 parts, Rhizoma Chuanxiong 10 ~ 20 parts, geranium 10 ~ 20 parts, Radix Paeoniae Rubra 10 ~ 20 parts, Rhizoma Corydalis 10 ~ 20 parts, Pheretima 10 ~ 20 parts, Fructus Psoraleae 10 ~ 20 parts, Pericarpium Citri Reticulatae 10 ~ 20 parts,

External used medicine comprises the crude drug of following weight portion: Olibanum 10 ~ 20 parts, Sanguis Draxonis 10 ~ 20 parts, Radix Dipsaci 10 ~ 20 parts, Radix Clematidis 10 ~ 20 parts, 10 ~ 20 parts, Flos Carthami, Rhizoma Homalomenae 10 ~ 20 parts, Radix Tripterygii Wilfordii 10 ~ 20 parts, Ramulus Cinnamomi 10 ~ 20 parts, Radix Aconiti Preparata 10 ~ 20 parts, Scorpio 10 ~ 20 parts, Herba speranskiae tuberculatae 10 ~ 20 parts, Rhizoma Polygoni Cuspidati 10 ~ 20 parts, Semen Strychni 10 ~ 20 parts, Eupolyphaga Seu Steleophaga 10 ~ 20 parts, the Radix Angelicae Dahuricae 10 ~ 20 parts.

2. treat the Chinese medicine composition of spleen kidney both deficiency type lumbar muscle strain according to claim 1, it is characterized in that, described endo-medicine comprises the crude drug of following weight portion: Fructus Amomi 10 ~ 15 parts, 10 ~ 15 parts, Poria, Cortex Magnoliae Officinalis 10 ~ 15 parts, Radix Gentianae Macrophyllae 10 ~ 15 parts, Rhizoma Dioscoreae 10 ~ 15 parts, Radix Dipsaci 10 ~ 15 parts, Herba Schizonepetae 10 ~ 15 parts, Radix Achyranthis Bidentatae 10 ~ 15 parts, Fructus Rosae Laevigatae 10 ~ 15 parts, Radix Angelicae Pubescentis 10 ~ 15 parts, Herba Taxilli 10 ~ 15 parts, Rhizoma Polygoni Cuspidati 10 ~ 20 parts, the Cortex Eucommiae 10 ~ 20 parts, Rhizoma Cibotii 10 ~ 20 parts, Lycopodium casuarinoides Spring 10 ~ 20 parts, Rhizoma Drynariae 10 ~ 20 parts, Rhizoma Chuanxiong 10 ~ 20 parts, geranium 10 ~ 20 parts, Radix Paeoniae Rubra 10 ~ 20 parts, Rhizoma Corydalis 10 ~ 20 parts, Pheretima 10 ~ 20 parts, Fructus Psoraleae 10 ~ 20 parts, Pericarpium Citri Reticulatae 10 ~ 20 parts,

External used medicine comprises the crude drug of following weight portion: Olibanum 10 ~ 15 parts, Sanguis Draxonis 10 ~ 15 parts, Radix Dipsaci 10 ~ 15 parts, Radix Clematidis 10 ~ 15 parts, 10 ~ 15 parts, Flos Carthami, Rhizoma Homalomenae 10 ~ 15 parts, Radix Tripterygii Wilfordii 10 ~ 15 parts, Ramulus Cinnamomi 10 ~ 20 parts, Radix Aconiti Preparata 10 ~ 20 parts, Scorpio 10 ~ 20 parts, Herba speranskiae tuberculatae 10 ~ 20 parts, Rhizoma Polygoni Cuspidati 10 ~ 20 parts, Semen Strychni 10 ~ 20 parts, Eupolyphaga Seu Steleophaga 10 ~ 20 parts, the Radix Angelicae Dahuricae 10 ~ 20 parts.

3. treat the Chinese medicine composition of spleen kidney both deficiency type lumbar muscle strain according to claim 1, it is characterized in that, described endo-medicine comprises the crude drug of following weight portion: Fructus Amomi 10 ~ 20 parts, 10 ~ 20 parts, Poria, Cortex Magnoliae Officinalis 10 ~ 20 parts, Radix Gentianae Macrophyllae 10 ~ 20 parts, Rhizoma Dioscoreae 10 ~ 20 parts, Radix Dipsaci 10 ~ 20 parts, Herba Schizonepetae 10 ~ 20 parts, Radix Achyranthis Bidentatae 10 ~ 20 parts, Fructus Rosae Laevigatae 10 ~ 20 parts, Radix Angelicae Pubescentis 10 ~ 20 parts, Herba Taxilli 10 ~ 20 parts, Rhizoma Polygoni Cuspidati 10 ~ 15 parts, the Cortex Eucommiae 10 ~ 15 parts, Rhizoma Cibotii 10 ~ 15 parts, Lycopodium casuarinoides Spring 10 ~ 15 parts, Rhizoma Drynariae 10 ~ 15 parts, Rhizoma Chuanxiong 10 ~ 15 parts, geranium 10 ~ 15 parts, Radix Paeoniae Rubra 10 ~ 15 parts, Rhizoma Corydalis 10 ~ 15 parts, Pheretima 10 ~ 15 parts, Fructus Psoraleae 10 ~ 15 parts, Pericarpium Citri Reticulatae 10 ~ 15 parts,

External used medicine comprises the crude drug of following weight portion: Olibanum 10 ~ 20 parts, Sanguis Draxonis 10 ~ 20 parts, Radix Dipsaci 10 ~ 20 parts, Radix Clematidis 10 ~ 20 parts, 10 ~ 20 parts, Flos Carthami, Rhizoma Homalomenae 10 ~ 20 parts, Radix Tripterygii Wilfordii 10 ~ 20 parts, Ramulus Cinnamomi 10 ~ 15 parts, Radix Aconiti Preparata 10 ~ 15 parts, Scorpio 10 ~ 15 parts, Herba speranskiae tuberculatae 10 ~ 15 parts, Rhizoma Polygoni Cuspidati 10 ~ 15 parts, Semen Strychni 10 ~ 15 parts, Eupolyphaga Seu Steleophaga 10 ~ 15 parts, the Radix Angelicae Dahuricae 10 ~ 15 parts.

4. according to any one of claims 1 to 3, treat a preparation method for the Chinese medicine composition of spleen kidney both deficiency type lumbar muscle strain, it is characterized in that, the dosage form of described endo-medicine is tablet, and its preparation method comprises:

5. treat the preparation method of the oral medicinal herb tablet of spleen kidney both deficiency type lumbar muscle strain according to claim 4, it is characterized in that, in described step a, first all crude drug are cut into coarse granule, then ethanol is put into, soak more than 2 hours, heating extraction 2 times, each 1-2 hour, removes supernatant, merge extractive liquid, 100-120 order filters, then is the ultrafiltration post ultrafiltration of 5000-10000 through the molecular weight that dams, when ultrafiltrate concentrating under reduced pressure relative density is 80 DEG C 1.38 extractum, stand for standby use, becomes component 1.

6. treat the preparation method of the oral medicinal herb tablet of spleen kidney both deficiency type lumbar muscle strain according to claim 4, it is characterized in that, in described step b, the medicinal residues that above-mentioned ethanol extraction is crossed are added water heating 1 ~ 2 hours reflux accounting for its quality 10 times amount and extract 2 times; Extraction time is 2 hours, 1 hour; Merge 2 extracting solution, extracting solution is centrifugal by tubular type, obtains centrifugal liquid, and centrifugal liquid is crossed D 101 macroporous resin and adsorbed, and first washes remove impurity with water, then carries out eluting with the ethanol of 70%, collects eluent, concentrating under reduced pressure, becomes extractum standing, for subsequent use as component 2.

7. treat the preparation method of the oral medicinal herb tablet of spleen kidney both deficiency type lumbar muscle strain according to claim 4, it is characterized in that, in described step c, above-mentioned two kinds of component extractum are merged, decompression recycling ethanol to be concentrated into liquor strength be 0.1g crude drug/mL, after sucking filtration, when the relative density of filtrate is about 20 DEG C 1.38; Above-mentioned filtrate is the macroporous adsorptive resins of 10L through volume, first uses deionized water or the distilled water eluting of 10 times of resin column volumes, then uses 95% ethanol elution of 5 times of resin column volumes, collect ethanol elution, remove solvent, obtain crude drug medicated powder, then add starch tabletting.

8. according to any one of claims 1 to 3, treat a preparation method for the Chinese medicine composition of spleen kidney both deficiency type lumbar muscle strain, it is characterized in that, the dosage form of described external used medicine is plaster, and its preparation method comprises:

9. according to any one of claims 1 to 3, treat a preparation method for the Chinese medicine composition of spleen kidney both deficiency type lumbar muscle strain, it is characterized in that, the dosage form of described external used medicine is ointment, and preparation method comprises:

B. all the other crude drug are added alcohol heating reflux and extract 2 times;

10. treat the preparation method of spleen kidney both deficiency type lumbar muscle strain according to claim 9, it is characterized in that, in described step a, first Radix Clematidis, Sanguis Draxonis, Olibanum, Ramulus Cinnamomi and the Rhizoma Homalomenae way of distillation are vaporized into crystalline particle, are then ground into fine powder for subsequent use; In described step b, all the other crude drug are added and accounts for its quality 5 ~ 8 times amount alcohol heating reflux and extract 2 times, described each 1 ~ 2 hour, 2 extracting solution are merged and leaves standstill; In described step c, the medicinal residues that above-mentioned ethanol extraction is crossed are added water heating 1 ~ 2 hours reflux accounting for its quality 10 times amount and extract 2 times; Extraction time is 2 hours, 1 hour; Merge 2 extracting solution, extracting solution is centrifugal by tubular type, obtains centrifugal liquid, and centrifugal liquid is crossed D 101 macroporous resin and adsorbed, and first washes remove impurity with water, then carries out eluting with the ethanol of 70%, collects eluent, one-tenth extractum stand for standby use; In described steps d, above-mentioned 2 kinds of extracting solution are merged, when concentrating under reduced pressure relative density is 80 DEG C 1.35 filtrate, reclaim ethanol, by gained filtrate adjustment proportion to 1.50, reduce pressure to obtain extractum, adds the crystalline powder prepared, and the glycerol that is in harmonious proportion stirs furnishing emulsifiable paste.