CN1857584A - Hypertension treating Chinese medicine preparation - Google Patents

Hypertension treating Chinese medicine preparation Download PDF

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CN1857584A
CN1857584A CNA200610011485XA CN200610011485A CN1857584A CN 1857584 A CN1857584 A CN 1857584A CN A200610011485X A CNA200610011485X A CN A200610011485XA CN 200610011485 A CN200610011485 A CN 200610011485A CN 1857584 A CN1857584 A CN 1857584A
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chinese medicine
herba
medicine preparation
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CN100473404C (en
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王信锁
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Beijing Jingui Chinese Medicine Research Institute Co. Ltd.
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王信锁
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Abstract

The hypertension treating Chinese medicine preparation is prepared with kendir, earthworm, wild chrysanthemum flower, selfheal, eucommia bark and other ten kinds of Chinese medicinal materials. It has the functions of clearing away heat, purging fire, calming liver and wind, nourishing Yin, benefiting kidney, promoting urination and lowering blood pressure. It is used in treating hypertension, and has determined curative effect, no toxic side effect, taking convenience and low cost.

Description

The hypertensive Chinese medicine preparation of a kind of treatment
Technical field
The present invention relates to the hypertensive Chinese medicine preparation of a kind of treatment, is that a kind of hypertension for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Hypertension be meant systolic arterial pressure and (or) diastolic pressure increases, and is normal with organ dysfunction or the organic systemic diseases of changing into feature such as the heart, brain, kidney and retinas, the hypertension of not illustrating fully as yet for reason so far is called essential hypertension.Hypertension is one of modal cardiovascular diseases, and hypertensive prevalence is made a definite diagnosis by China more than 20 years old be 5.896, and borderline hypertension is 3.3%, and adding up to the hypertension prevalence of being grown up more than 20 years old is 9.1%.Estimate China hyperpietic up to more than 6,000 ten thousand, and have and increase trend year by year.Hypertension not only makes evidence of coronary heart diseases be multiplied, and is to cause cerebrovascular accident, reaches the major reason of the heart, renal function injury.
According to the clinical manifestation of hypertension, Chinese medicine mainly is familiar with its etiology and pathogenesis by dizzy, headache.Commonly encountered diseases is because of there being the following aspects: disorder of emotion, and eating and drinking without temperance, the prolonged illness overwork, natural endowment is unusual.Under the effect of the above-mentioned cause of disease, the imbalance between YIN and YANG of body, internal organs, meridians, QI and blood dysfunction, just having formed is the hypertension of main performance with the dizziness headache.Clinically often be divided into: excessive rising of liver-YANG, the hepatic and renal YIN deficiency, stagnation of phlegm-damp in middle-JIAO, obstruction of collaterals by blood stasis, type Coryza Treated by Syndrome Differentiation such as deficiency of both YIN and YANG.Doctor trained in Western medicine is thought the etiology unknown of hypertension, long-term psychentonia and lack physical work, and family history of hypertension, overweight, the salt amount is too much in the diet, a large amount of smokers, its prevalence is higher.Hypertension pathology: the initial stage only is the tiny arteriospasm of whole body, does not have obvious pathomorphism and changes.Secular hypertension is hardened the tiny tremulous pulse of whole body, and transparent sample changes under the inner membrance, and tube wall thickens, the elastic fiber hyperplasia of petty action astillen, and the plump hardening in middle level, luminal stenosis, the most remarkable with the tiny arterial disease of kidney.In medium and large artery trunks, the inner membrance lipidosis be can occur, atheromatous plaque, thrombosis etc. formed.Be mainly in coronary artery, cerebral arteries, renal artery, artery of lower extremity.The accelerated hypertension disease claims the malignant hypertension disease again, at the tiny arterial wall with a plurality of organs such as kidneys fibrinoid necrosis is arranged, the smooth muscle fiber fracture, blood plasma and erythrocyte are exuded in the arterial wall, finally to luminal stenosis even obstruction, so that PRF, the state of an illness worsens rapidly.
Hypertension is one of contemporary modal disease, and people's life and health in serious threat, becomes difficult problem that needs to be resolved hurrily of medical circle.Though western medicine controlling blood pressure effectively raises, can not improve symptom ideally, reverse target organ damage.Though Chinese medicine is not ideal enough aspect instant efficacy of antihypertensive treatment, is improving symptom and the aspects such as protective effect of target organs such as the heart, brain, kidney are had certain advantage.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.
The purpose of this invention is to provide a kind of determined curative effect, safe ready, little, the cheap pure Chinese medicine of side effect.
The present invention is made by the following weight proportion raw material:
5~15 parts of 3~7 parts of Flos Chrysanthemi Indicis of 10~30 parts of Pheretimas of Herba Apocyni veneti
5~15 parts of 3~7 parts of Herba Taxilli of 10~30 parts of Cortexs Eucommiae of Spica Prunellae
3~7 parts of 3~7 parts of Fructus Cannabiss of 10~30 parts of Rhizoma Chuanxiongs of Ramulus Uncariae Cum Uncis
3~7 parts of 3~7 portions of Herba Artemisiae Scopariaes of 3~7 parts of Rhizoma Anemarrhenaes of Radix Gentianae
3~7 parts of 3~7 portions of Radix Notoginseng are picked up on 3~7 parts of mountains of Semen Plantaginis with the fingers
The weight proportion of each raw material of optimization formula of the present invention is:
8~12 parts of 4~6 parts of Flos Chrysanthemi Indicis of 15~25 parts of Pheretimas of Herba Apocyni veneti
8~12 parts of 4~6 parts of Herba Taxillis of 15~25 parts of Cortexs Eucommiae of Spica Prunellae
4~6 parts of 4~6 parts of Fructus Cannabiss of 15~25 parts of Rhizoma Chuanxiongs of Ramulus Uncariae Cum Uncis
4~6 parts of 4~6 portions of Herba Artemisiae Scopariaes of 4~6 parts of Rhizoma Anemarrhenaes of Radix Gentianae
4~6 parts of 4~6 portions of Radix Notoginseng are picked up on 4~6 parts of mountains of Semen Plantaginis with the fingers
The weight proportion of each raw material of optimum formula of the present invention is:
10 parts of 5 parts of Flos Chrysanthemi Indicis of 20 parts of Pheretimas of Herba Apocyni veneti
10 parts of 5 parts of Herba Taxillis of 20 parts of Cortexs Eucommiae of Spica Prunellae
5 parts of 5 parts of Fructus Cannabiss of 20 parts of Rhizoma Chuanxiongs of Ramulus Uncariae Cum Uncis
5 parts of 5 portions of Herba Artemisiae Scopariaes of 5 parts of Rhizoma Anemarrhenaes of Radix Gentianae
5 parts of 5 portions of Radix Notoginseng are picked up on 5 parts of mountains of Semen Plantaginis with the fingers
Drug action mechanism among the present invention is as follows:
The Herba Apocyni veneti nature and flavor are sweet, bitter, cool.Return Liver Channel.Have suppressing the hyperactive liver and calm the nerves, heat clearing away blood pressure lowering, heart tonifying diuretic effect.Cure mainly palpitation and insomnia, be used for dizziness due to hyperactivity of liver-YANG, edema oliguria, hypertension, heart disease, neurasthenia, hepatitis abdominal distention, nephritis edema, allergic asthma flu etc." Chinese medicine medicine for preventing pharmacology and application " the 807th page
The Pheretima nature and flavor are salty, cold.Go into liver, spleen, lung, urinary bladder channel.Have heat clearing away, suppressing the hyperactive liver, Zhichuan, collateral dredging diuretic effect.Cure mainly high fanatical dry, convulsion with spasms, headache due to pathogenic wind-heat, conjunctival congestion, apoplexy and hemiplegia, pant, sore throat, arthralgia, bleeding from the gum, urinary obstruction, scrofula, mumps, skin infection, hyperpyrexia, bronchial asthma, hypertension, psychosis, ulcer of the lower limb, eczema, erysipelas, burn and scald, fracture etc." Chinese medicine medicine for preventing pharmacology and application " the 522nd page
Flos Chrysanthemi Indici nature and flavor hardship, suffering, be slightly cold.Return liver, heart channel.Effect with wind and heat dispersing, subduing swelling and detoxicating.Can treat anemopyretic cold, pneumonia, diphtheria, gastroenteritis, hypertension, furuncle, carbuncle, aphtha, erysipelas, eczema pemphigus etc." Chinese medicine medicine for preventing pharmacology and application " the 1112nd page
Spica Prunellae nature and flavor hardship, suffering, cold.Return liver, gallbladder meridian.Have clearing away liver-fire, make eye bright, eliminating stagnation, repercussive effect.Can treat scrofula, goiter, acute mastitis, conjunctival congestion and swelling pain, photophobia shed tears, have a headache dizzy, thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension, pulmonary tuberculosis, acute icteric infectious hepatitis, metrorrhagia, leukorrhagia, bones and muscles pain etc." Chinese medicine medicine for preventing pharmacology and application " the 1001st page
Cortex Eucommiae nature and flavor are sweet, wet.Return liver, kidney channel.Has invigorating the liver and kidney, bone and muscle strengthening, antiabortive effect.Can treat hypertension and doublely suffer from a deficiency of the kidney, back ache, foot and knee flaccidity, dribbling urination, uncontrolled urination are itched, vaginal bleeding during pregnancy is desired to fall, have a dizzy spell, frequent fetal movement etc." Chinese medicine medicine for preventing pharmacology and application " the 623rd page
Herba Taxilli nature and flavor hardship, sweet, flat.Return liver, kidney channel.Have invigorating the liver and kidney, bone and muscle strengthening, remove rheumatism, the meridian dredging, beneficial blood, antiabortive effect.Can treat that soreness of waist and knee joint, muscles and bones flaccidity are weak, hemiplegia, beriberi, anemofrigid-damp arthralgia, vaginal bleeding during pregnancy metrorrhagia, lack of lactation after delivery, coronary heart disease, hypertension etc." Chinese medicine medicine for preventing pharmacology and application " the 1060th page
The Ramulus Uncariae Cum Uncis nature and flavor are sweet, cool.Return liver, heart channel.Has the heat clearing away suppressing the hyperactive liver, the effect of the arresting convulsion that relieves dizziness, high fever, infantile convulsions, epilepsy, etc.Can treat pediatric epilepsy scared, adult's blood pressure is higher, and is dizzy, dizzy, married woman's eclamposia." Chinese medicine voluminous dictionary " the 1670th page.
Rhizoma Chuanxiong nature and flavor suffering, perfume (or spice).Return liver, gallbladder, pericardium channel.Has blood-activating and qi-promoting, the effect of wind-expelling pain-stopping.Can treat menoxenia, the amenorrhea dysmenorrhea, difficult labour produces stasis of blood stop block pain, lump in the abdomen stomachache, the twinge of the breast side of body, arthralgia due to cold clonic spasm of the muscle, tumbling and swelling, headache due to pathogenic wind-heat, rheumatic arthralgia, skin infection swells and ache, placenta retention, cerebral ischemia, coronary heart disease, angina pectoris, atherosclerosis, hypertension, radiotherapy, leukopenia due to the chemotherapy, juvenile myopia, vitamin e deficiency, flu is dizzy, external plug nose treating malaria disease etc." Chinese medicine medicine for preventing pharmacology and application " the 171st page.
The Fructus Cannabis nature and flavor are sweet, flat.Return spleen, stomach, large intestine channel.Have and moisturize, laxation, treating stranguria, the effect of invigorating blood circulation.Can treat blood deficiency and depleted fluid, dryness of the intestine constipation, pyretic stranguria, migratory arthralgia, dysentery, menoxenia, scabies, tinea leprosy etc." Chinese medicine medicine for preventing pharmacology and application " the 342nd page.
Radix Gentianae nature and flavor hardship, cold.Return liver, gallbladder meridian.Have eliminating pathogen in the liver gallbladder fire, the clear part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels is wet, relieving convulsion making eye bright, and the malaria protozoon is good for the stomach, the effect that protects the liver.Can treat that Liver Channel intenseness of heat, infantile convulsion are manic, encephalitis B, headache, conjunctival congestion, pharyngalgia, jaundice, hematodiarrhoea, the swollen skin infection of pain, scrotum swell and ache, pudendum pruritus due to damp pathogen, hypertension dizziness tinnitus, chest and hypochondrium, acute infectious hepatitis, cystitis, skin infection swell and ache etc." Chinese medicine medicine for preventing pharmacology and application " the 413rd page.
Rhizoma Anemarrhenae nature and flavor hardship, sweet, cold.Return lung, stomach, kidney channel.Has clearing away heat-fire, the effect of promoting the production of body fluid and moisturizing.Can treat that fever caused by exogenous pathogenic factors, hyperpyrexia excessive thirst, tuberculosis heating, cough due to lung-heat, osteopyrexia and fever, interior-heat are quenched one's thirst, the dryness of the intestine constipation, dysuria, diabetes etc." Chinese medicine medicine for preventing pharmacology and application " the 817th page.
Herba Artemisiae Scopariae nature and flavor hardship, Xin Liang, be slightly cold.Return spleen, stomach, liver and gall, urinary bladder channel.Have clearing away damp-heat, jaundice eliminating subcutaneous ulcer, blood circulation promoting and blood stasis dispelling, promote blood circulation let out poison, anthelmintic, stimulated hepatic cell regeneration, control exterior deficiency, perspiration arranged, the effect of blood pressure lowering.Can treat icterohepatitis, cholecystitis, cholelithiasis, biliary tract ascarid, epidemic febrile disease from the beginning of the feeling sick of alternate attack of chill and fever, summer-heat, vomiting, jaundice oliguria, eczema pruritus, dysuria, pruritus due to wind pathogen skin ulcer scabies etc." Chinese medicine medicine for preventing pharmacology and application " the 890th page.
The Semen Plantaginis nature and flavor are sweet, be slightly cold.Return liver, kidney, lung, small intestinal, urinary bladder channel.Has clearing away heat and promoting diuresis, eliminating dampness by diuresis antidiarrheal, liver heat removing and eyesight improving, the effect of removing heat from the lung and dissipating phlegm.Can treat the cough due to lung-heat, urinary system infection, calculus, gastritis edema, dysuria, enteritis, bacillary dysentery, acute icterohepatitisshock, bronchitis, acute eye conjunctivitis, stranguria with turbid discharge, leukorrhagia, hematuria, edema, hematodiarrhoea is had loose bowels, epistaxis, conjunctival congestion and swelling pain, sore throat tonsillitis, cough, skin ulcer etc." Chinese medicine medicine for preventing pharmacology and application " the 291st page.
The mountain is picked up nature and flavor acid, sweet, tepor with the fingers.Return spleen, stomach, Liver Channel.Effect with promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.Can treat hypertension, coronary heart disease and control that meat is long-pending, wine long-pending, dyspepsia, gastral cavilty distension, lump in the abdomen, phlegm retention, feeling of fullness, acid regurgitation, dysentery, hemorrhoidal hamorrhage, lumbago, hernia, blood stasis amenorrhea, produce exceed the time limit unlikely, the newborn food stagnation of children's and the infantile malnutrition skin ulcer is itched, dermatitis rhus, chilblain, skin skin ulcer, chronic bronchitis, hyperlipidemia, bacillary dysentery, enteritis, taeniasis etc. of occipital headache, stasis of blood resistance, trusted subordinate's twinge, lochiorrhea, menstruation." Chinese medicine medicine for preventing pharmacology and application " the 141st page.
Sweet, the little hardship of Radix Notoginseng nature and flavor, temperature.Return liver, stomach, large intestine channel.Has the dissipating blood stasis hemostasis, the effect of subduing swelling and relieving pain.Can treat haematemesis, hemoptysis, epistaxis, have blood in stool, dysentery, metrorrhagia, lump in the abdomen, puerperal blood faints, retention of lochia, traumatic hemorrhage, breast ventral spine pain, fall and pounce on blood stasis, carbuncle pain, acute pharyngolaryngitis, Light-headedness, tinnitus, coronary heart disease, angina pectoris, acute necrosis sections enteritis, venom, bee sting, rheumatic arthritis disease, hypertension etc." Chinese medicine medicine for preventing pharmacology and application " the 60th page.
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", with Herba Apocyni veneti, Flos Chrysanthemi Indici, Spica Prunellae, Ramulus Uncariae Cum Uncis and Radix Gentianae is monarch drug, Pheretima, the Cortex Eucommiae, Herba Taxilli, Semen Plantaginis and Herba Artemisiae Scopariae are ministerial drug, and pick up with the fingers on the Rhizoma Anemarrhenae, mountain, Radix Notoginseng, Fructus Cannabis and Rhizoma Chuanxiong are adjuvant.All medicine phases and common tool clearing away heat-fire, suppressing the hyperactive liver to relieve the wind syndrome, the nourishing YIN for benefiting the kidney, the effect of diuretic antihypertensive, treatment hypertension, determined curative effect has no side effect, and taking convenience is cheap.
Chinese medicine preparation of the present invention, can add the medicine acceptable carrier when being prepared into medicament, described medicine acceptable carrier can be: starch, sucrose, lactose, mannitol, silicon derivative, cellulose family and derivant thereof, alginate, gelatin, polyvinylpyrrolidone, glycerol, soil temperature 80, agar, calcium carbonate, calcium bicarbonate, surfactant, Polyethylene Glycol, cyclodextrin, beta-schardinger dextrin-, phospholipid material, Kaolin, Pulvis Talci, calcium stearate, magnesium stearate etc.
Chinese medicine preparation of the present invention can be any pharmaceutically useful dosage form, and these dosage forms comprise: tablet, sugar coated tablet, film coated tablet, enteric coated tablet, capsule, hard capsule, soft capsule, oral liquid, suck agent, granule, electuary, pill, powder, unguentum, sublimed preparation, suspensoid, powder, solution, injection, suppository, ointment, plaster, cream, spray, drop, patch.Preparation of the present invention, peroral dosage form preferably, as: tablet, capsule, oral agents, buccal tablet, granule, electuary, pill, powder, suspensoid, powder, solution, drop, drop pill.Preferred Chinese medicine preparation is capsule, tablet, granule.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment hypertension of the Chinese medicine of respectively distinguishing the flavor of, and does not have chemical sweeting agent, and is nontoxic to human body.Show that through animal acute toxicity experiment the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and mice is 45g crude drug/kg to the maximum tolerated dose of medicine of the present invention, is 160 times of clinical people's consumption, and safety of medicine is reliable.
2, the present invention need not decoct, no bitterness sense, rich in proteins in the medicine, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid, also contain various trace elements such as Saponin, plant sterol and calcium, be beneficial to absorption of human body, health invigorating, and taking convenience.
3, the present invention can effectively treat and control hypertension, higher healing rehabilitation efficacy is arranged for I phase and II phase hyperpietic, has improved its life quality and time greatly for III phase hyperpietic.
Further specify the present invention to hypertensive therapeutic effect below by the clinical practice example.
Hypertension curative effect determinate standard: 1, more than the produce effects diastolic pressure decline 10mmHg, and reach normal range; Though diastolic pressure is not reduced to normally but is descended more than the 20mmHg.2, effectively diastolic pressure descends not as good as 10mmHg, but has reached normal range; Diastolic pressure is the preceding 10~19mmHg that descends of treatment, but does not reach normal range; Systolic pressure is more than the preceding decline 30mmHg of treatment.Must possess wherein 1.3, invalidly do not reach above standard person.
The clinical observation on the therapeutic effect result is as follows:
Through clinical observation treatment hyperpietic 32 examples, male's 20 examples wherein, women's 12 examples.Be II phase hyperpietic.Take embodiment 1 capsule, each 2-10 grain, every day three to four times, eliminating cold for resuscitation water send down, and take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.Produce effects 17 examples account for 5396, and effective 13 examples account for 41%, and invalid 2 examples account for 6%, total effective rate 94%.
The specific embodiment
Embodiment 1: capsule takes by weighing raw material by following proportioning:
10 parts of 5 parts of Flos Chrysanthemi Indicis of 20 parts of Pheretimas of Herba Apocyni veneti
10 parts of 5 parts of Herba Taxillis of 20 parts of Cortexs Eucommiae of Spica Prunellae
5 parts of 5 parts of Fructus Cannabiss of 20 parts of Rhizoma Chuanxiongs of Ramulus Uncariae Cum Uncis
5 parts of 5 portions of Herba Artemisiae Scopariaes of 5 parts of Rhizoma Anemarrhenaes of Radix Gentianae
5 parts of 5 portions of Radix Notoginseng are picked up on 5 parts of mountains of Semen Plantaginis with the fingers
Production method is to get Pheretima earlier, the Cortex Eucommiae and Radix Notoginseng clean dry are crushed to 120~200 order fine powders, get Herba Apocyni veneti again, Flos Chrysanthemi Indici, Spica Prunellae, Herba Taxilli, Ramulus Uncariae Cum Uncis, Rhizoma Chuanxiong, Fructus Cannabis, Radix Gentianae, the Rhizoma Anemarrhenae, Herba Artemisiae Scopariae, Semen Plantaginis and mountain are picked up with the fingers and are decocted with water twice, 1.5~2 hours for the first time, 0.5~1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree~85 when spending, the clear paste of relative density 1.08~1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, and reclaimed ethanol, when 50 degree~55 are spent, be concentrated into the clear paste of relative density 1.30~1.32, again with clear paste and Pheretima, the Cortex Eucommiae and Radix Notoginseng fine powder mixing, drying is ground into fine powder, incapsulates.Adorn 0.3 gram for every, common half an hour ante cibum is oral, and eliminating cold for resuscitation water send down.One time 2~10, three to four times on the one.One month is a course of treatment.
Embodiment 2: tablet takes by weighing raw material by following proportioning:
10 parts of 5 parts of Flos Chrysanthemi Indicis of 20 parts of Pheretimas of Herba Apocyni veneti
10 parts of 5 parts of Herba Taxillis of 20 parts of Cortexs Eucommiae of Spica Prunellae
5 parts of 5 parts of Fructus Cannabiss of 20 parts of Rhizoma Chuanxiongs of Ramulus Uncariae Cum Uncis
5 parts of 5 portions of Herba Artemisiae Scopariaes of 5 parts of Rhizoma Anemarrhenaes of Radix Gentianae
5 parts of 5 portions of Radix Notoginseng are picked up on 5 parts of mountains of Semen Plantaginis with the fingers
Production method is to get Pheretima earlier, the Cortex Eucommiae and Radix Notoginseng clean dry are crushed to 120~200 order fine powders, get Herba Apocyni veneti again, Flos Chrysanthemi Indici, Spica Prunellae, Herba Taxilli, Ramulus Uncariae Cum Uncis, Rhizoma Chuanxiong, Fructus Cannabis, Radix Gentianae, the Rhizoma Anemarrhenae, Herba Artemisiae Scopariae, Semen Plantaginis and mountain are picked up with the fingers and are decocted with water twice, 1.5~2 hours for the first time, 0.5~1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree~85 when spending, the clear paste of relative density 1.08~1.10, adding ethanol makes clear paste contain the alcohol amount to reach 70%, left standstill 24 hours, and reclaimed ethanol, when 50 degree~55 are spent, be concentrated into the clear paste of relative density 1.30~1.32, again with clear paste and Pheretima, the Cortex Eucommiae and Radix Notoginseng fine powder mixing, drying is ground into fine powder, adds appropriate amount of starch, alcohol granulation, after the drying, add an amount of magnesium stearate, tabletting, sugar coating are promptly.Common half an hour ante cibum is oral, and eliminating cold for resuscitation water send down.One time 2~10, three to four times on the one.One month is a course of treatment.
Embodiment 3: granule takes by weighing raw material by following proportioning:
10 parts of 5 parts of Flos Chrysanthemi Indicis of 20 parts of Pheretimas of Herba Apocyni veneti
10 parts of 5 parts of Herba Taxillis of 20 parts of Cortexs Eucommiae of Spica Prunellae
5 parts of 5 parts of Fructus Cannabiss of 20 parts of Rhizoma Chuanxiongs of Ramulus Uncariae Cum Uncis
5 parts of 5 portions of Herba Artemisiae Scopariaes of 5 parts of Rhizoma Anemarrhenaes of Radix Gentianae
5 parts of 5 portions of Radix Notoginseng are picked up on 5 parts of mountains of Semen Plantaginis with the fingers
Production method is to get Pheretima earlier, the Cortex Eucommiae and Radix Notoginseng clean dry are crushed to 120~200 order fine powders, get Herba Apocyni veneti again, Flos Chrysanthemi Indici, Spica Prunellae, Herba Taxilli, Ramulus Uncariae Cum Uncis, Rhizoma Chuanxiong, Fructus Cannabis, Radix Gentianae, the Rhizoma Anemarrhenae, Herba Artemisiae Scopariae, Semen Plantaginis and mountain are picked up with the fingers and are decocted with water twice, 1.5~2 hours for the first time, 0.5~1 hour for the second time, merge decocting liquid twice, filter, filtrate is concentrated into 80 degree~85 when spending, the clear paste of relative density 1.08~1.10 adds ethanol and makes clear paste contain the alcohol amount to reach 7096, left standstill 24 hours, reclaim ethanol, when spending, 50 degree~55 are concentrated into the clear paste of relative density 1.30~1.32, again with clear paste and Pheretima, the Cortex Eucommiae and Radix Notoginseng fine powder mixing, drying, be ground into fine powder, add an amount of sucrose and soluble starch, alcohol granulation, the pack of dry back is promptly.Usually half an hour ante cibum warm boiled water, one time 1~3 bag, three to four times on the one.One month is a course of treatment.

Claims (6)

1, the hypertensive Chinese medicine preparation of a kind of treatment.It is characterized in that it is made by the following weight proportion raw material:
5~15 parts of 3~7 parts of Flos Chrysanthemi Indicis of 10~30 parts of Pheretimas of Herba Apocyni veneti
5~15 parts of 3~7 parts of Herba Taxillis of 10~30 parts of Cortexs Eucommiae of Spica Prunellae
3~7 parts of 3~7 parts of Fructus Cannabiss of 10~30 parts of Rhizoma Chuanxiongs of Ramulus Uncariae Cum Uncis
3~7 parts of 3~7 portions of Herba Artemisiae Scopariaes of 3~7 parts of Rhizoma Anemarrhenaes of Radix Gentianae
3~7 parts of 3~7 portions of Radix Notoginseng are picked up on 3~7 parts of mountains of Semen Plantaginis with the fingers
2, the hypertensive Chinese medicine preparation of a kind of treatment according to claim 1, wherein the weight proportion of each raw material is:
8~12 parts of 4~6 parts of Flos Chrysanthemi Indicis of 15~25 parts of Pheretimas of Herba Apocyni veneti
8~12 parts of 4~6 parts of Herba Taxillis of 15~25 parts of Cortexs Eucommiae of Spica Prunellae
4~6 parts of 4~6 parts of Fructus Cannabiss of 15~25 parts of Rhizoma Chuanxiongs of Ramulus Uncariae Cum Uncis
4~6 parts of 4~6 portions of Herba Artemisiae Scopariaes of 4~6 parts of Rhizoma Anemarrhenaes of Radix Gentianae
4~6 parts of 4~6 portions of Radix Notoginseng are picked up on 4~6 parts of mountains of Semen Plantaginis with the fingers
3, the hypertensive Chinese medicine preparation of a kind of treatment according to claim 1, wherein the weight proportion of each raw material is:
10 parts of 5 parts of Flos Chrysanthemi Indicis of 20 parts of Pheretimas of Herba Apocyni veneti
10 parts of 5 parts of Herba Taxillis of 20 parts of Cortexs Eucommiae of Spica Prunellae
5 parts of 5 parts of Fructus Cannabiss of 20 parts of Rhizoma Chuanxiongs of Ramulus Uncariae Cum Uncis
5 parts of 5 portions of Herba Artemisiae Scopariaes of 5 parts of Rhizoma Anemarrhenaes of Radix Gentianae
5 parts of 5 portions of Radix Notoginseng are picked up on 5 parts of mountains of Semen Plantaginis with the fingers
4, the Chinese medicine preparation of claim 1-3 is to be fit to medicinal various dosage forms.
5, the Chinese medicine preparation of claim 4 is tablet, capsule, oral agents, buccal tablet, granule, electuary, pill, powder, suspensoid, powder, solution, drop, drop pill.
6, the Chinese medicine preparation of claim 4 is capsule, tablet, granule.
CNB200610011485XA 2006-03-14 2006-03-14 Hypertension treating Chinese medicine preparation Expired - Fee Related CN100473404C (en)

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100558378C (en) * 2007-05-29 2009-11-11 沈信堂 The hypertensive Chinese medicine of a kind of treatment
CN102614390A (en) * 2012-05-01 2012-08-01 马守云 Medicine for treating hypertension
CN102698124A (en) * 2012-01-17 2012-10-03 李付德 Traditional Chinese medicinal composition for treating yang-deficiency bipolar type systolic and diastolic hypertension
CN103006996A (en) * 2012-12-31 2013-04-03 苗洁清 Medicine for treating accelerated hypertension
WO2015018124A1 (en) * 2013-08-09 2015-02-12 Tian Yi Er Traditional chinese medicine preparation for reducing blood pressure and preparation method thereof
CN104474342A (en) * 2014-12-11 2015-04-01 胡波 Tea cream for drinking of people with high blood pressure, high blood sugar and hyperlipidemia and preparation method of tea cream
CN105079586A (en) * 2015-10-07 2015-11-25 青岛云天生物技术有限公司 Traditional Chinese medicine composition for treating hypertension
CN105816699A (en) * 2016-03-25 2016-08-03 广西大学 Sparassis crispa healthcare oral liquid with lipid and pressure reducing effects and preparation method thereof
CN112493587A (en) * 2020-12-18 2021-03-16 鲁南制药集团股份有限公司 Separated anti-virus health mask

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100558378C (en) * 2007-05-29 2009-11-11 沈信堂 The hypertensive Chinese medicine of a kind of treatment
CN102698124A (en) * 2012-01-17 2012-10-03 李付德 Traditional Chinese medicinal composition for treating yang-deficiency bipolar type systolic and diastolic hypertension
CN102698124B (en) * 2012-01-17 2013-11-06 李付德 Traditional Chinese medicinal composition for treating yang-deficiency bipolar type systolic and diastolic hypertension
CN102614390A (en) * 2012-05-01 2012-08-01 马守云 Medicine for treating hypertension
CN103006996A (en) * 2012-12-31 2013-04-03 苗洁清 Medicine for treating accelerated hypertension
CN103006996B (en) * 2012-12-31 2014-03-12 威海市妇女儿童医院 Medicine for treating accelerated hypertension
WO2015018124A1 (en) * 2013-08-09 2015-02-12 Tian Yi Er Traditional chinese medicine preparation for reducing blood pressure and preparation method thereof
CN104474342A (en) * 2014-12-11 2015-04-01 胡波 Tea cream for drinking of people with high blood pressure, high blood sugar and hyperlipidemia and preparation method of tea cream
CN105079586A (en) * 2015-10-07 2015-11-25 青岛云天生物技术有限公司 Traditional Chinese medicine composition for treating hypertension
CN105816699A (en) * 2016-03-25 2016-08-03 广西大学 Sparassis crispa healthcare oral liquid with lipid and pressure reducing effects and preparation method thereof
CN112493587A (en) * 2020-12-18 2021-03-16 鲁南制药集团股份有限公司 Separated anti-virus health mask

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