CN104324314A - Pharmaceutical composition for treating gastropathy - Google Patents

Pharmaceutical composition for treating gastropathy Download PDF

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Publication number
CN104324314A
CN104324314A CN201410618110.4A CN201410618110A CN104324314A CN 104324314 A CN104324314 A CN 104324314A CN 201410618110 A CN201410618110 A CN 201410618110A CN 104324314 A CN104324314 A CN 104324314A
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radix
rhizoma
drugs
pharmaceutical composition
stomach
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李穆
董金华
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Hebei University of Science and Technology
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Hebei University of Science and Technology
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Abstract

The invention discloses a pharmaceutical composition for treating gastropathy, which is prepared by taking astragalus, radix codonopsis, poria cocos and rhizoma atractylodis macrocephalae for reinforcing qi, tonifying spleen, and strengthening and consolidating body resistance as monarch drugs, taking radix aucklandiae, rhizoma cyperi, pericarpium citri reticulatae viride, dried tangerine or orange peel, pinellia ternate, fructus amomi, and endothelium corneum gigeriae galli for soothing liver, resolving depression, promoting the circulation of qi, relieving epigastric distention, helping digestion, killing parasites, and aiding digestion as ministerial drugs, taking cuttle bones, lumbricus, panax notoginseng, ovateleaf holly bark, corydalis yanhusuo, bletilla striata, halloysitum rubrum, and fructus mume for astringing to stop bleeding, promoting blood circulation to arrest pain, and repairing mucosa as adjuvant drugs, and taking rhizoma coptidis, fructus forsythiae, radix geutianae, dandelion, honey-fried licorice roots, and radix angelicae for clearing away heat and toxic materials, clearing damp, discharging fire, coordinating the drug actions of a prescription, and introducing drugs to stomach as conductant drugs. The pharmaceutical composition disclosed by the invention is low in traditional Chinese medicine treatment cost and short in treatment period, has a good treatment effect, and has no toxic or side effect.

Description

A kind of pharmaceutical composition for the treatment of gastropathy
Technical field
The present invention relates to a kind of pharmaceutical composition for the treatment of gastropathy.
Background technology
Gastropathy, is actually the general designation of many diseases, and a variety of disease is relevant to gastropathy.As uncomfortable in upper abdomen gastral cavilty portion, pain
Bitterly, after meal glutted, belch, return acid, even Nausea and vomiting etc.The common clinically gastropathy of doctor trained in Western medicine has the innocent and malignant tumour of acute gastritis, chronic gastritis, gastric ulcer, duodenal ulcer, gastroduodenal complex ulcer, polyp of stomach, gastric calculus, stomach, also has prolapse of gastric mucosa, acute gastric dilatation, pyloric obstruction etc.
The gastropathy cause of disease mainly contains following several:
1. after acute gastritis, mucosal lesion is not healed lastingly.
2. helicobacter pylori infections.
3. be addicted to drink for a long time drink strong tea, espresso, food is pungent excessively and the unreasonable living habit such as eating and drinking too much at one meal, smoking, depression.
4. often take and have infringement and medicine excitatory, as aspirin, indometacin, glucocorticoid, antibiotic, antitumor drug etc. to gastric mucosa.
5. some chronic diseases, as chronic hepatitis, chronic nephritis, uremia, severe diabetes etc.
The modal clinical manifestation of gastropathy has epigastric discomfort or pain, nausea,vomiting,diarrhea, inappetence.The symptom of gastritis and duodenal ulcer is then epigastrium burning pain, particularly between two meals, early occurs before the meal or after drinking orange juice, coffee.Severe patient can have tarry stool, melena or hemafecia.
The Chinese medicine and the Western medicine that are now commercially used for the treatment of gastropathy are varied, when taking, the property of medicine is slower, the course for the treatment of is longer, cure rate is not high, and medicine on market mostly can only mitigate the disease, can not cure, some medicine has larger side effect, needs of patients prolonged administration of drugs, therapeutic effect is undesirable.
Summary of the invention
Technical problem to be solved by this invention is to provide that a kind of medical expense is low, and treatment cycle is short, and therapeutic effect is good, the pharmaceutical composition of the treatment gastropathy had no side effect.
The present invention adopts following technical scheme: the present invention adopts following ratio of weight and number component to make:
Radix Astragali 10g-30g, Radix Codonopsis 10g-30g, Rhizoma Atractylodis Macrocephalae 10g-30g, Poria 15g-30g, Radix Glycyrrhizae Preparata 10g-15g, Radix Aucklandiae 10g-15g, Fructus Amomi 3g-9g, Os Sepiae 15g-30g, Endothelium Corneum Gigeriae Galli 9g-30g, Radix Angelicae Dahuricae 10g-20g, Fructus Forsythiae 10g-20g, Radix Gentianae 10g-20g, Herba Taraxaci 15g-30g, Rhizoma Coptidis 3g-9g, Rhizoma Pinelliae 6g-12g, Rhizoma Corydalis 10g-15g, Cortex Ilicis Rotundae 10g-15g, Radix Notoginseng 3g-6g, Pericarpium Citri Reticulatae 10g-15g, Pericarpium Citri Reticulatae Viride 10g-15g, Rhizoma Cyperi 6g-9g, Pheretima 10g-15g, Fructus Mume 10g-20g, Pseudobulbus Bletillae (Rhizoma Bletillae) 3g-15g, Halloysitum Rubrum 3g-12g.
Good effect of the present invention is as follows:
In pharmaceutical composition of the present invention:
1. the Radix Astragali: sweet in the mouth, warm in nature.Return lung, spleen channel.Air making-up and spleen enlivening, function: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Cure mainly: the deficiency of vital energy is weak, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.Normal and the compatibility such as Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae; Modern pharmacology: the Radix Astragali is one of drug of first choice improving immunity of organisms.
2. Radix Codonopsis: sweet in the mouth, warm in nature.Return spleen, lung meridian.Function cures mainly invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.
3. the Rhizoma Atractylodis Macrocephalae: bitter in the mouth, sweet, warm in nature.Return spleen, stomach warp.Invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, frequent fetal movement.
4. Poria: sweet in the mouth, light, property is put down.GUIXIN, spleen, kidney channel.Cure mainly: edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia, hysteromyoma.Pharmacology: diuresis.Can improve humoral immunization merit, can suppress the permeability of blood capillary, have direct relaxation effect in vitro intestinal, smooth muscle contraction amplitude is reduced, tension force declines.Affect internal metabolism, have conciliation effect to electrolytical balance, and can blood glucose be reduced.
5. Radix Glycyrrhizae Preparata: sweet in the mouth, property is put down.GUIXIN, lung, spleen, stomach warp.Function cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion compositions toxicity, strong.In side, Radix Glycyrrhizae Preparata gets its warming middle-JIAO for easing the stomach to be in harmonious proportion main effect.
6. the Radix Aucklandiae: acrid in the mouth is bitter, warm in nature.Return lung, liver, spleen channel." Thunder God concocts property of medicine solution ": GUIXIN, lung, liver, spleen, stomach, bladder the six channels.Function cures mainly: promoting the circulation of QI to relieve pain, warming middle-JIAO for easing the stomach.Control the invasion by pathogenic cold stagnation of QI, chest and abdomen swelling and pain, vomiting, has loose bowels, dysentery tenesmus, colic of cold type.
7. Fructus Amomi: acrid in the mouth, warm in nature.Return spleen, stomach warp.Function cures mainly: during circulation of qi promoting is adjusted, stomach function regulating, is amusing.Control stomachache painful abdominal mass swollen, anorexia dyspepsia, dysphagic vomiting, diarrhea due to cold pathogen cold-dysentery, pregnant fetal movement.
8. Endothelium Corneum Gigeriae Galli: sweet in the mouth; Property is put down. return spleen; Stomach; Kidney; Urinary bladder channel. function cures mainly; Strengthening the spleen to promote digestion; Arresting seminal emission; Eliminating mass fossil.Cure mainly dyspepsia; Eating accumulation; Vomiting regurgitation; To have loose bowels dysentery; Infantile malnutrition; Seminal emission; The enuresis; Frequent micturition; Urinary system calculus and cholelithiasis; Lump in the abdomen amenorrhea; Sore throat tonsillitis; Ulcerative gingivitis aphtha.
9. Os Sepiae: salty in the mouth, puckery, warm in nature.Return spleen, kidney channel.Effect: astringing to arrest bleeding, treating spontaneous emission and leukorrhagia, relieving gastric hyperacidity to alleviate stomachache, removing dampness sore.For Peptic Ulcers, hyperchlorhydria, hematemesis and epistaxis, metrorrhagia is had blood in stool, emission and spermatorrhea, leucorrhea with red and white discharge.
10. the Radix Angelicae Dahuricae: acrid in the mouth, warm in nature.Return stomach, large intestine, lung meridian.Function cures mainly: loose wind dehumidifying, understand things pain-stopping, detumescence and apocenosis.For headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache
11. Fructus Forsythiaes: bitter in the mouth, cool in nature.Gui Jing: the heart, liver, gallbladder meridian." Thunder God concocts property of medicine solution ": enter the heart, liver, gallbladder, stomach, three burnt, large intestine the six channels.Function cures mainly: heat clearing away, removing toxic substances, eliminating stagnation, detumescence.Control warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.
12. Radix Gentianaes: bitter in the mouth, cold in nature.Return liver, gallbladder meridian.Function with cure mainly: heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire.For jaundice due to damp-heat, swelling of the vulva pudendal pruritus, leukorrhagia, persistent erection of the penis, eczema pruritus, conjunctival congestion, deaf, hypochondriac pain, bitter taste, convulsion with spasms.
13. Herba Taraxacis: bitter but sweet flavor, cold in nature.Return liver, stomach warp.Function cures mainly: heat-clearing and toxic substances removing, diuresis eliminating stagnation.Control acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.
14. Rhizoma Coptidis: bitter in the mouth, cold in nature.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Function with cure mainly: heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.It is burning hot that Rhizoma Coptidis (processed with wine) is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.For conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Tie mutually for cold and heat, damp and hot middle resistance, feeling of fullness is vomitted.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomiting acid regurgitation.
15. Rhizoma Pinelliaes: acrid in the mouth, warm in nature; Poisonous.Return spleen, stomach, lung meridian.Function cures mainly: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.For abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm is had a headache, vomiting regurgitation, and breast gastral cavity painful abdominal mass is vexed, globus hystericus; Raw with external treatment carbuncle sucutaneous nodule.Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) is used for stopping nausea and vomiting by lowering the adverse flow of QI.
16. Rhizoma Corydalis: acrid in the mouth, hardship, warm in nature, GUIXIN, liver, spleen channel.Effect: blood-activating and qi-promoting pain relieving;
17. Cortex Ilicis Rotundaes: bitter in the mouth, cold in nature.Function cures mainly: heat-clearing and toxic substances removing, dampness removing, pain relieving.Cure cold heating, tonsillitis, laryngopharynx swelling and pain, acute, chronic hepatitis, acute gastroenteritis, gastric and duodenal ulcers, rheumatic arthritis, traumatic injury, burn.Modern pharmacology: relieving spasm to stop pain, hemostasis.
18.. Radix Notoginseng: sweet and slightly bitter taste, warm in nature.Return liver, stomach, large intestine channel.Function cures mainly: hemostasis, dissipating blood stasis, detumescence, analgesic therapy.Control haematemesis, hemoptysis, epistaxis, have blood in stool, dysentery, metrorrhagia ， mass in the abdomen, puerperal blood faints, retention of lochia, falls and flutters blood stasis, traumatic hemorrhage, carbuncle pain.
19. Pheretimas: salty in the mouth, cold in nature.Return liver, spleen, urinary bladder channel.Function with cure mainly: heat clearing away is calmed the frightened, and dredging collateral is relievingd asthma, diuresis.For unconsciousness due to high fever, infantile convulsion is twitched, arthralgia, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema, hypertension.
20. Fructus Mumes: sour in the mouth, puckery, property is put down.Return liver, spleen, lung, large intestine channel.Astringe the lung, astringing intestine to stop diarrhea, promotes the production of body fluid, relieving colic caused by ascaris.Function cures mainly: chronic cough of deficiency lung; Deficiency-heat excessive thirst; Chronic malaria; Chronic diarrhea; Dysentery; Have blood in stool; Hematuria; Metrorrhagia; The ascariasis of biliary tract is suffered from abdominal pain; Vomiting; Ancylostomiasis.
21. Pericarpium Citri Reticulataes: acrid in the mouth is bitter, warm in nature.Return spleen, lung meridian.Function cures mainly: regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.Fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.
22. Pericarpium Citri Reticulatae Virides: bitter in the mouth is pungent, slightly warm in nature. return liver, gallbladder meridian. function cures mainly: soothing the liver dispelling the stagnated QI, eliminating stagnation expectorant.Control breast side of body gastralgia, hernia, food stagnation, swelling of the breast, nodule in the breast, chronic malaria addiction block.
23. Rhizoma Cyperis: the micro-hardship of acrid in the mouth is sweet, property is put down.Return liver, tri-jiao channel." Thunder God concocts property of medicine solution ": enter lung, liver, spleen, stomach four warp.Function cures mainly: resolving depression of regulating the flow of vital energy, pain relieving regulating menstruation.Treating the liver discomfort in the stomach, depression of QI, breast abdomen distending pain over the hypochondrium, phlegm retention feeling of fullness, menoxenia, bleeding not during menses.
24.. the Pseudobulbus Bletillae (Rhizoma Bletillae): bitter in the mouth, sweet, puckery, cold nature.Return lung, liver, stomach warp.Function cures mainly: astringing to arrest bleeding, detumescence and promoting granulation.Spit blood for hemoptysis, traumatic hemorrhage, sore swollen toxin, chapped skin; Pulmonary tuberculosis hemoptysis, ulcer haemorrhage.
25. Halloysitum Rubrums: sweet in the mouth, puckery, sour; Warm in nature; Return spleen, stomach, the heart, large intestine channel.Effect: astringing intestine to stop diarrhea, astringing to arrest bleeding, removing dampness sore, granulation promoting.
The Radix Astragali, Radix Codonopsis, Poria, Rhizoma Atractylodis Macrocephalae air making-up and spleen enlivening in pharmaceutical composition of the present invention, strengthening the body resistance is monarch drug.
The Radix Aucklandiae, Rhizoma Cyperi, Pericarpium Citri Reticulatae Viride, Pericarpium Citri Reticulatae, the Rhizoma Pinelliae, Fructus Amomi, Endothelium Corneum Gigeriae Galli soothing liver-QI for relieving depression, promoting the circulation of QI to alleviate the stagnation in middle-JIAO, the parasite killing that helps digestion is aid digestion is ministerial drug.
Os Sepiae, Pheretima, Radix Notoginseng, Cortex Ilicis Rotundae, Rhizoma Corydalis, the Pseudobulbus Bletillae (Rhizoma Bletillae), Halloysitum Rubrum, Fructus Mume astringing to arrest bleeding, promoting blood circulation and stopping pain, reparation mucosa is adjuvant drug.
Rhizoma Coptidis, Fructus Forsythiae, Radix Gentianae, Herba Taraxaci, Radix Glycyrrhizae Preparata, Radix Angelicae Dahuricae heat-clearing and toxic substances removing, dehumidifying pathogenic fire purging, coordinating the actions of various ingredients in a prescription, priming reach stomach for making medicine.
The usage and dosage of pharmaceutical composition of the present invention is: by ratio of weight and the number of copies for medicine, is clayed into power by Radix Notoginseng, by all the other medicines appropriate cold water soak about a hour.Subsequently again by soak pharmaceutical composition boiled after, decoct 15 minutes with slow fire, pour out medicinal liquid.Add appropriate cold water more boiled, decoct 20 minutes with slow fire, pour out medicinal liquid.Add again appropriate cold water boiled after, decoct 25 minutes with slow fire, pour out medicinal liquid.By three medicinal liquid mixing, divide and take with the Notoginseng Root of milled is same for three times.Deal of the present invention is potion, every day potion, before or after meals is taken.The present invention can produce in a large number, is condensed into dissolved granule and takes after also can having decocted medicinal liquid.Take according to the state of an illness, ordinary circumstance six to three ten doses can be cured.
Criterion of therapeutical effect is decided to be: diet stomach, can normal diet without sensation of pricking, and drug withdrawal was no longer recurred after 7 days, stomach
Without the sense of discomfort, raw food is diet not, is as healthy as usual as curing; Have rosy cheeks, limbs are strong, and appetite is good, and stomach is even paroxysmal pain sense, stool day 1 twice not slivering, for effectively; Pale complexion, limb adynamia, does not have appetite, still has paroxysmal pain, stool day more than three times, defecates shapeless, for invalid.
Adopt the embodiment of the present invention 1 medicine composite for curing gastropathy 200 example, man 120 example, female 80 example, wherein effective 146 people, effective percentage 73%; Cure 46 people, cure rate 23%; Separately there are 8 people invalid, inefficiency 4%.
Cure case:
1, Wang, man, 40 years old, suffer from serious gastric erosion, polyp of stomach, congestion and edema before taking medicine, gastral cavilty paroxysmal pain, many places are seen the doctor for treatment invalid, as long as five years, Lee comes here and seeks medical advice misery, takes Chinese medicine described in the embodiment of the present invention 1, within several minutes, pain just obviously alleviates, and has just fully recovered after medication 30 doses.
2, Liu, female, 23 years old, student, between student at school's current, diet was irregular, often stomachache, flatulence, and recurrent exerbation is invalid through many hospitalizes, fully recovers after taking seven doses, Chinese medicine described in the embodiment of the present invention 2.
3, foretell certain, man, 33 years old, because job demand is on the drink, has superficial gastritis, chronic gastritis, gastric ulcer, gastric erosion, at any time pain, after drinking, pain increases the weight of, and is clearly better after taking this medicine, take recovery from illness after 30 doses, Chinese medicine described in the embodiment of the present invention 3, drinks now also not bitterly.
Detailed description of the invention
The specific embodiment of the invention is as shown in the table:

Claims (1)

1. treat the pharmaceutical composition of gastropathy for one kind, it is characterized in that it adopts the component of following parts by weight to make: Radix Astragali 10g-30g, Radix Codonopsis 10g-30g, Rhizoma Atractylodis Macrocephalae 10g-30g, Poria 15g-30g, Radix Glycyrrhizae Preparata 10g-15g, Radix Aucklandiae 10g-15g, Fructus Amomi 3g-9g, Os Sepiae 15g-30g, Endothelium Corneum Gigeriae Galli 9g-30g, Radix Angelicae Dahuricae 10g-20g, Fructus Forsythiae 10g-20g, Radix Gentianae 10g-20g, Herba Taraxaci 15g-30g, Rhizoma Coptidis 3g-9g, Rhizoma Pinelliae 6g-12g, Rhizoma Corydalis 10g-15g, Cortex Ilicis Rotundae 10g-15g, Radix Notoginseng 3g-6g, Pericarpium Citri Reticulatae 10g-15g, Pericarpium Citri Reticulatae Viride 10g-15g, Rhizoma Cyperi 6g-9g, Pheretima 10g-15g, Fructus Mume 10g-20g, Pseudobulbus Bletillae (Rhizoma Bletillae) 3g-15g, Halloysitum Rubrum 3g-12g.
CN201410618110.4A 2014-11-06 2014-11-06 Pharmaceutical composition for treating gastropathy Pending CN104324314A (en)

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CN110604804A (en) * 2019-08-23 2019-12-24 刘世杰 Traditional Chinese medicine formula for treating stomach diseases
CN116139242A (en) * 2021-11-19 2023-05-23 富顺大生堂医院 Traditional Chinese medicine for treating reflux esophagitis, gastric ulcer and duodenal ulcer

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110604804A (en) * 2019-08-23 2019-12-24 刘世杰 Traditional Chinese medicine formula for treating stomach diseases
CN116139242A (en) * 2021-11-19 2023-05-23 富顺大生堂医院 Traditional Chinese medicine for treating reflux esophagitis, gastric ulcer and duodenal ulcer

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Application publication date: 20150204