CN1857558A - Chinese medicine for treating children's hyperkinetic syndrome and its preparing method - Google Patents

Abstract

The Chinese medicine for treating children's hyperkinetic syndrome is prepared with prepared rhizome of rehmannia, tortoise shell, polygala root, grassleaved sweetflag rhizome, dogwood and other six kinds of Chinese medicinal materials as well as proper amount of supplementary material. The preparation process includes the steps of grinding partial materials to obtain fine powder, water decocting partial materials and filtering to obtain filtrate, alcohol reflux extracting partial materials and filtering to obtain the second filtrate, merging two kinds of filtrate, concentrating to obtain extractum, drying and crushing to obtain the second kinds of powder, mixing two kinds of powder, palletizing, tabletting and coating. The Chinese medicine has raised stability, high quality, fast acting and easy taking.

Description

A kind of Chinese medicine and preparation method for the treatment of childhood hyperkinetic syndrome

(1) technical field

The present invention relates to Chinese patent medicine, particularly relate to a kind of Chinese medicine and preparation method for the treatment of childhood hyperkinetic syndrome.

(2) background technology

Childhood hyperkinetic syndrome is the higher a kind of psychological behavior disorder illness of sickness rate among the school age child, can have a strong impact on the mental health of infant and destroy the learning capacity of infant.The intelligence of this class infant normally or normal substantially, but study, behavior and emotion aspect defectiveness.Clinical symptoms is comparatively outstanding with school age population, and it mainly shows as absent minded, and how moving multi-lingual, impulsion is wilful, tired anxious irritability, so that influence school grade, bring difficulty for the head of a family and Teachers'Educational.Report that according to domestic and international interrelated data this disease prevalence in the pupil is 1%-10%, boy is ill many than girl, and it is more that the premature infant suffers from this disease.This disease is the disease of motion, thinking, feelings will, spirit, special send out in the childhood period.Motherland's medical science is thought: refreshing being hidden by the heart, is the dominant force of other ergasias such as soul will, commands and coordination whole body function and people's ergasia, and is converted into external language, action, behavior by intrinsic mind activity.Kidney storing will, kidney essense abundance, then skill is sensitive ingeniously, the light many power of strength.Head is a house of intelligence, and brains are given birth to by kidney, the kidney essense abundance, and then excess of marrow-reservoir is clear-headed and clear-sighted.If heart kidney deficiency, brain is not filled, and mind then can occur and lax, and mind is not clever, moves and symptoms such as clumsiness more.The hepatic and renal YIN deficiency and the childhood hyperkinetic syndrome that causes, the hepatic and renal YIN deficiency after the prolonged illness, or hinder in the cloudy Tianjin of losing of plain body, children's's body constitution originally has the characteristics of " YANG often being in excess, YIN often being in shortage " in addition, so the Liver and kidney deficiency of YIN-blood, can not Ru Yangjinmai, and cause stirring-up of pathogenic wind in the interior resulting from deficiency, deficiency of YIN monarch's phase hyperactivity of fire, upward floating of YANG in deficiency condition, refreshing moving will becomes, and malaise is laxed and cause mind, fidgety irritability, how moving multi-lingual etc.The suitable nourishing yin and purging fire of the rule of treatment, subduing hyperactive YANG to ease mental disorders.This Chinese medicine is that pure Chinese medicinal preparation system is formulated through processing by ten Herba indigoferae Pseudotinctoriae such as Radix Rehmanniae Preparata, Carapax Et Plastrum Testudinis, Radix Polygalae, Rhizoma Acori Graminei, Fructus Corni, Rhizoma Dioscoreae, Os Draconis, Poria, Cortex Phellodendri, Bombyx Batryticatus, Exocarpium Citri Grandises, its function is a nourishing the liver and kidney, have one's ideas straightened out, mind tranquilizing and the heart calming is used for that childhood hyperkinetic syndrome has good efficacy due to the hepatic and renal YIN deficiency.The Chinese medicine of commercially available treatment childhood hyperkinetic syndrome (trade name is moved Yiganning capsule more), preparation is a capsule, the part infant is swallowed comparatively difficult, and the easy moisture absorption of capsule is lumpd and is gone bad, and is not easy to storage, and it is changed system into tablet, not only increased stability of drug, simultaneously also make things convenient for infant to take, carried and store, met the modern requirement of Chinese medicine preparation.

(3) summary of the invention

The objective of the invention is at the problems referred to above, a kind of Chinese medicinal tablet and preparation method that makes things convenient for the treatment childhood hyperkinetic syndrome that infant takes is provided, trade name is many moving peaceful sheets.

The technical scheme that adopts is:

A kind of Chinese medicine for the treatment of childhood hyperkinetic syndrome is that appropriate amount of auxiliary materials is made tablet by Chinese crude drug Radix Rehmanniae Preparata, Carapax Et Plastrum Testudinis, Radix Polygalae, Rhizoma Acori Graminei, Fructus Corni, Rhizoma Dioscoreae, Os Draconis, Poria, Cortex Phellodendri, Bombyx Batryticatus, Exocarpium Citri Grandis ten Herba indigoferae Pseudotinctoriae.Its compatibility is Radix Rehmanniae Preparata 300g, Carapax Et Plastrum Testudinis 300g, Radix Polygalae 200g, Rhizoma Acori Graminei 50g, Fructus Corni 150g, Rhizoma Dioscoreae 150g, Os Draconis 300g, Poria 120g, Cortex Phellodendri 120g, Bombyx Batryticatus 120g, Exocarpium Citri Grandis 50g, and adjuvant 26.25g mixed preparing forms.

Described a kind of preparation method for the treatment of the Chinese medicinal tablet of childhood hyperkinetic syndrome, it is standby to get Radix Rehmanniae Preparata 300g, Carapax Et Plastrum Testudinis 300g, Radix Polygalae 200g, Rhizoma Acori Graminei 50g, Fructus Corni 150g, Rhizoma Dioscoreae 150g, Os Draconis 300g, Poria 120g, Cortex Phellodendri 120g, Bombyx Batryticatus 120g, Exocarpium Citri Grandis 50g ten Herba indigoferae Pseudotinctoriae.More than ten simply, get Rhizoma Acori Graminei, that Exocarpium Citri Grandis is ground into fine powder is standby, Carapax Et Plastrum Testudinis, Os Draconis, Poria, Bombyx Batryticatus decoct with water three times, add 5 times of amounts of water at every turn, decoct 2 hours, collecting decoction filters filtrate for later use; Radix Rehmanniae Preparata, Radix Polygalae, Fructus Corni, Rhizoma Dioscoreae and Cortex Phellodendri add 60% alcohol reflux three times, add 3 times of amounts at every turn, extracted 1 hour, merge extractive liquid, filters, filtrate recycling ethanol is to there not being the alcohol flavor, add above-mentioned filtrate, being concentrated into relative density is 1.39 clear paste in 80 ℃ of surveys, drying, pulverize, with Rhizoma Acori Graminei, Exocarpium Citri Grandis fine powder mixing; Add calcium sulfate 15g, pregelatinized Starch 7.5g, microcrystalline Cellulose 3.75g, mixing; Use 45% alcohol granulation, drying; Add the magnesium stearate of grain amount 1% and 0.5% Pulvis Talci behind the granulate, mixing is pressed into 1000 of the slice, thin pieces of the heavy 0.4g of substrate, bag film-coat (the coating rear panel heavily is 0.42g), promptly.

Above-mentioned a kind of preparation method for the treatment of the Chinese medicinal tablet of childhood hyperkinetic syndrome, behind the medicated powder, add starch 26.25g, mixing is used 45% alcohol granulation, drying; Add the magnesium stearate of grain amount 1% and 0.5% Pulvis Talci behind the granulate, mixing is pressed into 1000 of the slice, thin pieces of the heavy 0.4g of substrate, and sugar coating gets product.

This tablet has increased stability of drug for bag film-coat and sugar coated tablet, makes things convenient for infant to take, carry and store, and this tablet is a pure Chinese medicinal preparation, adopt advanced extraction and preparation technique to make with extra care and form, the active ingredient height, curative effect is rapid, have nourishing the liver and kidney, have one's ideas straightened out, the mind tranquilizing and the heart calming effect.

(4) specific embodiment

Embodiment one

A kind of Chinese medicine and preparation method for the treatment of childhood hyperkinetic syndrome is that to get Radix Rehmanniae Preparata 300g, Carapax Et Plastrum Testudinis 300g, Radix Polygalae 200g, Rhizoma Acori Graminei 50g, Fructus Corni 150g, Rhizoma Dioscoreae 150g, Os Draconis 300g, Poria 120g, Cortex Phellodendri 120g, Bombyx Batryticatus 120g, Exocarpium Citri Grandis 50g ten Herba indigoferae Pseudotinctoriae standby.More than ten simply, get Rhizoma Acori Graminei, that Exocarpium Citri Grandis is ground into fine powder is standby, Carapax Et Plastrum Testudinis, Os Draconis, Poria, Bombyx Batryticatus decoct with water three times, add 5 times of amounts of water at every turn, decoct 2 hours, collecting decoction filters filtrate for later use; Radix Rehmanniae Preparata, Radix Polygalae, Fructus Corni, Rhizoma Dioscoreae and Cortex Phellodendri add 60% alcohol reflux three times, add 3 times of amounts at every turn, extracted 1 hour, merge extractive liquid, filters, filtrate recycling ethanol is to there not being the alcohol flavor, add above-mentioned filtrate, being concentrated into relative density is 1.39 clear paste in 80 ℃ of surveys, drying, pulverize, with Rhizoma Acori Graminei, Exocarpium Citri Grandis fine powder mixing; Add calcium sulfate 15g, pregelatinized Starch 7.5g, microcrystalline Cellulose 3.75g, mixing; Use 45% alcohol granulation, drying; Add the magnesium stearate of grain amount 1% and 0.5% Pulvis Talci behind the granulate, mixing is pressed into 1000 of the slice, thin pieces of the heavy 0.4g of substrate, bag film-coat (the coating rear panel heavily is 0.42g), promptly.

Embodiment two

A kind of Chinese medicine and preparation method for the treatment of childhood hyperkinetic syndrome, it is standby to get Radix Rehmanniae Preparata 300g, Carapax Et Plastrum Testudinis 300g, Radix Polygalae 200g, Rhizoma Acori Graminei 50g, Fructus Corni 150g, Rhizoma Dioscoreae 150g, Os Draconis 300g, Poria 120g, Cortex Phellodendri 120g, Bombyx Batryticatus 120g, Exocarpium Citri Grandis 50g ten Herba indigoferae Pseudotinctoriae.More than ten simply, get Rhizoma Acori Graminei, that Exocarpium Citri Grandis is ground into fine powder is standby, Carapax Et Plastrum Testudinis, Os Draconis, Poria, Bombyx Batryticatus decoct with water three times, add 5 times of amounts of water at every turn, decoct 2 hours, collecting decoction filters filtrate for later use; Radix Rehmanniae Preparata, Radix Polygalae, Fructus Corni, Rhizoma Dioscoreae and Cortex Phellodendri add 60% alcohol reflux three times, add 3 times of amounts at every turn, extract 1 hour, merge extractive liquid, filters, and filtrate recycling ethanol is to there not being the alcohol flavor, add above-mentioned filtrate, being concentrated into relative density is 1.39 clear paste in 80 ℃ of surveys, drying, pulverize, with Rhizoma Acori Graminei, Exocarpium Citri Grandis fine powder mixing, add starch 26.25g, mixing, use 45% alcohol granulation, drying; Add the magnesium stearate of grain amount 1% and 0.5% Pulvis Talci behind the granulate, mixing is pressed into 1000 of the slice, thin pieces of the heavy 0.4g of substrate, sugar coating, promptly.

Usage and consumption: oral, a 3-5 sheet, three times on the one or follow the doctor's advice.

Claims (4)

1, a kind of Chinese medicine for the treatment of childhood hyperkinetic syndrome is that the appropriate amount of auxiliary materials mixed preparing is characterized in that making tablet by Chinese crude drug Radix Rehmanniae Preparata, Carapax Et Plastrum Testudinis, Radix Polygalae, Rhizoma Acori Graminei, Fructus Corni, Rhizoma Dioscoreae, Os Draconis, Poria, Cortex Phellodendri, Bombyx Batryticatus, Exocarpium Citri Grandis ten Herba indigoferae Pseudotinctoriae.

2, a kind of Chinese medicine for the treatment of childhood hyperkinetic syndrome according to claim 1, be by Chinese crude drug Radix Rehmanniae Preparata, Carapax Et Plastrum Testudinis, Radix Polygalae, Rhizoma Acori Graminei, Fructus Corni, Rhizoma Dioscoreae, Os Draconis, Poria, Cortex Phellodendri, Bombyx Batryticatus, Exocarpium Citri Grandis ten Herba indigoferae Pseudotinctoriae, appropriate amount of auxiliary materials is hybridly prepared into tablet, it is characterized in that Radix Rehmanniae Preparata 300g, Carapax Et Plastrum Testudinis 300g, Radix Polygalae 200g, Rhizoma Acori Graminei 50g, Fructus Corni 150g, Rhizoma Dioscoreae 150g, Os Draconis 300g, Poria 120g, Cortex Phellodendri 120g, Bombyx Batryticatus 120g, Exocarpium Citri Grandis 50g, adjuvant 26.25g.

3, a kind of preparation method for the treatment of the Chinese medicinal tablet of childhood hyperkinetic syndrome according to claim 1, it is standby to it is characterized in that getting Radix Rehmanniae Preparata 300g, Carapax Et Plastrum Testudinis 300g, Radix Polygalae 200g, Rhizoma Acori Graminei 50g, Fructus Corni 150g, Rhizoma Dioscoreae 150g, Os Draconis 300g, Poria 120g, Cortex Phellodendri 120g, Bombyx Batryticatus 120g, Exocarpium Citri Grandis 50g ten Herba indigoferae Pseudotinctoriae; More than ten simply, get Rhizoma Acori Graminei, that Exocarpium Citri Grandis is ground into fine powder is standby, Carapax Et Plastrum Testudinis, Os Draconis, Poria, Bombyx Batryticatus decoct with water three times, add 5 times of amounts of water at every turn, decoct 2 hours, collecting decoction filters filtrate for later use; Radix Rehmanniae Preparata, Radix Polygalae, Fructus Corni, Rhizoma Dioscoreae and Cortex Phellodendri add 60% alcohol reflux three times, add 3 times of amounts at every turn, extracted 1 hour, merge extractive liquid, filters, filtrate recycling ethanol is to there not being the alcohol flavor, add above-mentioned filtrate, being concentrated into relative density is 1.39 clear paste in 80 ℃ of surveys, drying, pulverize, with Rhizoma Acori Graminei, Exocarpium Citri Grandis fine powder mixing; Add calcium sulfate 15g, pregelatinized Starch 7.5g, microcrystalline Cellulose 3.75g, mixing; Use 45% alcohol granulation, drying; Add the magnesium stearate of grain amount 1% and 0.5% Pulvis Talci behind the granulate, mixing is pressed into 1000 of the slice, thin pieces of the heavy 0.4g of substrate, the bag film-coat, promptly.

4, a kind of preparation method for the treatment of the Chinese medicinal tablet of childhood hyperkinetic syndrome according to claim 1, it is characterized in that described total powder after, add starch 26.25g, mixing is used 45% alcohol granulation, drying; Add the magnesium stearate of grain amount 1% and 0.5% Pulvis Talci behind the granulate, mixing is pressed into 1000 of the slice, thin pieces of the heavy 0.4g of substrate, and sugar coating promptly.