CN1814304A - Biotechnological treating method of biomass for stomach intestine contrast-media - Google Patents

Biotechnological treating method of biomass for stomach intestine contrast-media Download PDF

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Publication number
CN1814304A
CN1814304A CN 200510104547 CN200510104547A CN1814304A CN 1814304 A CN1814304 A CN 1814304A CN 200510104547 CN200510104547 CN 200510104547 CN 200510104547 A CN200510104547 A CN 200510104547A CN 1814304 A CN1814304 A CN 1814304A
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China
Prior art keywords
biomass
contrast agent
enzyme
superfines
processing
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CN 200510104547
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Chinese (zh)
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CN100356983C (en
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辛益群
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Shandong University
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Shandong University
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Abstract

This invention is a biological technique processing method of gastrointestinal series agent using biomass. It is enzyme processing technique of gastrointestinal series agent using biomass superfines, series enzyme processing is assisted done on bases of machining of gastrointestinal series agent using biomass superfines, especially processing of cellulose enzyme type series. So the biological powder can be further thinned on bases of superfines, and it can be more easier disperse. Affinity of contrast agent is improved. Bad substance is reduced after microwave heating and cooking processing and its flavor is better.

Description

The gastrointestinal contrast agent biotechnology processing method of biomass
Technical field:
The present invention relates to the biotechnology processing method of a kind of gastrointestinal contrast agent, belong to powdered biomass or medical adjuvant processing method and technology field with biomass.
Background technology:
The applicant has mentioned materials such as the protein that utilizes zymotechnic to handle bran coat Testa Tritici or the like biomass to exist, starch in the 4/6th page of ZL03112182.9 description, for example " desire improves the relative amount of its edible fiber class material; need carry out some processing, for example fully rinses on the wheat bran materials such as protein, starch such as gluten cell; And general enzymatic treatment removes materials such as protein, starch, waits its edible fiber class material is increased ".But propose to utilize the cellulose enzyme to handle biomass such as bran coat Testa Tritici, especially propose to utilize the plain enzyme of super fine biological matter powder accessory fibers after the processing of cellulose enzyme processing machine to handle so that powder particle is trickleer, clean and increase the affinity of its dispersibility and raising and barium sulfate powder.
Summary of the invention:
A kind of gastrointestinal contrast agent biotechnology processing method of biomass, it is characterized in that being meant the enzyme processing technology of gastrointestinal contrast agent with the biomass superfines, be in gastrointestinal contrast agent biomass superfines≤100 microns machinings, generally be on the basis of common pulverizing processing equipment manufacturing limit, the auxiliary seriation enzyme that carries out is handled, the particularly processing of cellulose enzyme series, make the surface roughening of biomass superfines, be easy to adsorb inorganic contrast agent ultra-micro powder, be easy to form biomass superfines surface and fully adsorb the complex structure of wrapping up in inorganic contrast agent ultra-micro powders such as band barium sulfate, reach further refinement simultaneously, so that granule is littler, disperse better or the like the advantage of the affinity of better and contrast agent.Generally be the enzyme processing that the cuticular substance in corn or the like source is added biotechnology,
The seriation enzyme is handled and is meant: protease, amylase, lipase, cellulase; Wherein based on cellulase, other enzyme can add and can not add, and can singlely add, and also can compoundly add.
The cellulose enzyme is meant cellulase, hemicellulase, pectase, lignoenzyme or the like, and is single or compound.Advantage: through particularly biotechnology enzyme processing of series of processes, make powdered biomass at the enterprising step refining in ultra-micro powder basis, roughening, easier dispersion, the affinity of raising and contrast agent is wrapped up in the complex structure of being with inorganic contrast agent ultra-micro powders such as barium sulfate thereby be easy to form the abundant absorption in biomass superfines surface; Microwave heating and steaming simultaneously fried and handled, and increases local flavor, reduces undesirable substance.
The specific embodiment:
More than embodiment 1. Testa Tritici, microwave heating to 100 ℃, dry dryly while hot, directly enter next step! Perhaps add pulverizer again and pulverize, make about 104~850 microns of granularities (the granularity specification is with reference to US4774096), carry out the seriation enzyme then and handle (also can be, rather than adopt enzyme process) with reference to the US4774096 Hydrolyze method.(1) amylase is handled: the enzyme that is dissolved in water, fully stir, and adjust PH to 5.5~7 with aqueous hydrochloric acid solution (being not more than 2N), be incubated 78 ℃, 1 hour, clean filter pressing recovery or centrifugal recovery, drying or directly enter next step; (2) Protease Treatment: in order to be fit to the up and down sour environment of flow process, adopt acid protease, PH2.5~4, the suitableeest 3,30~50 ℃ of temperature ranges, about 40 ℃ of optimum temperatures.Adjust PH with aqueous hydrochloric acid solution, be incubated 1 hour, clean, filter pressing is reclaimed or centrifugal recovery, drying, and super micron mill is pulverized to superfines, generally is not more than 100 microns, enters next step; (3) cellulose treatment: the enzyme that is dissolved in water, fully stir, adjust PH to 4~5 with aqueous hydrochloric acid solution (being not more than 2N), be incubated 50 ℃, 0.2~1 hour, microscopy, as seen powder particle emanates, refinement, surperficial roughening, stopped reaction, fully clean centrifugal recovery, drying, packed for standby use.Note grasping the degree that enzyme is handled.
Embodiment 2, and with embodiment 1, difference is that Testa Tritici is transformed to Testa oryzae.
Embodiment 3, and with embodiment 1,2, difference is to heat 100 ℃ or above sterilization processing, and micronizing is a superfines then, generally is not more than 100 microns, and directly cellulose treatment has kept partially protein and starch material.
Embodiment 4, and with embodiment 1,2,3, difference is that Testa Tritici and Testa oryzae are replaced into other biomass material, such as Cortex beans or the like.
Embodiment 5, and with embodiment 1,2,3,4, difference is that microwave heating is replaced into slow fire parch drying.Can reach and improve flavor substance local flavor, the purpose of high temperature sterilization again.
Embodiment 6, and with embodiment 1,2,3,4, difference is that microwave heating is replaced into and steams, and is dry then.Reach and improve flavor substance local flavor, the purpose of high temperature sterilization again.
Embodiment 7, and with embodiment 1, difference is the pectase and 5% hemicellulase of the compound adding 5% of cellulase.

Claims (3)

1, a kind of gastrointestinal contrast agent biotechnology processing method of biomass, it is characterized in that being meant the enzyme processing technology of gastrointestinal contrast agent with the biomass superfines, be on the basis of gastrointestinal contrast agent with biomass superfines≤100 microns machinings, the auxiliary seriation enzyme that carries out is handled, the particularly processing of cellulose enzyme series, make the surface roughening of biomass superfines, be easy to adsorb inorganic contrast agent ultra-micro powder, be easy to form biomass superfines surface fully absorption wrap up in the complex structure of inorganic contrast agent ultra-micro powder such as band barium sulfate, reach simultaneously biological particles diminished, good dispersion, purpose with the raising of contrast agent affinity.
2, a kind of gastrointestinal contrast agent as claimed in claim 1 is characterized in that with the biotechnology processing method of biomass the processing of seriation enzyme is meant: protease, amylase, lipase, cellulase; Based on cellulose treatment, other enzyme adds or does not add single adding or compound adding.
3, a kind of gastrointestinal contrast agent as claimed in claim 1 is characterized in that with the biotechnology processing method of biomass the cellulose enzyme is meant cellulase, hemicellulase, pectase, lignoenzyme, and is single or compound.
CNB2005101045477A 2005-11-18 2005-11-18 Biotechnological treating method of biomass for stomach intestine contrast-media Expired - Fee Related CN100356983C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNB2005101045477A CN100356983C (en) 2005-11-18 2005-11-18 Biotechnological treating method of biomass for stomach intestine contrast-media

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Application Number Priority Date Filing Date Title
CNB2005101045477A CN100356983C (en) 2005-11-18 2005-11-18 Biotechnological treating method of biomass for stomach intestine contrast-media

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CN1814304A true CN1814304A (en) 2006-08-09
CN100356983C CN100356983C (en) 2007-12-26

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Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001513571A (en) * 1997-08-29 2001-09-04 ザ リセックス カンパニー インコーポレイテッド Treatment of diabetes, hyperglycemia and hypoglycemia
AU2001236972A1 (en) * 2000-02-15 2001-08-27 Lipogenics, Inc. Enzymatic processing of rice bran to produce edible products
CN1202866C (en) * 2003-04-23 2005-05-25 山东大学 Gastrointestinal contrast agent containing biomass

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