CN100356983C - Biotechnological treating method of biomass for stomach intestine contrast-media - Google Patents
Biotechnological treating method of biomass for stomach intestine contrast-media Download PDFInfo
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- CN100356983C CN100356983C CNB2005101045477A CN200510104547A CN100356983C CN 100356983 C CN100356983 C CN 100356983C CN B2005101045477 A CNB2005101045477 A CN B2005101045477A CN 200510104547 A CN200510104547 A CN 200510104547A CN 100356983 C CN100356983 C CN 100356983C
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- superfines
- contrast agent
- enzyme
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Abstract
The present invention relates to a biotechnological treating method of biomass for gastrointestinal contrast agents, particularly to an enzyme treatment and processing technology of biomass superfine powder for the gastrointestinal contrast agents. On a basis that the biomass superfine powder is used for mechanical processing for the gastrointestinal contrast agents, seriation enzyme treatment is carried out in an auxiliary mode, particularly the enzymes serial treatment for cellulose, so that the biomass powder is refined further on the basis of the superfine powder. The biomass powder is easy to disperse and improve affinity with the contrast agents, and simultaneously, the biomass powder is heated and cooked with a microware so as to increase flavour and reduce bad matters.
Description
Technical field:
The present invention relates to the biotechnology processing method of a kind of gastrointestinal contrast agent, belong to powdered biomass or medical adjuvant processing method and technology field with biomass.
Background technology:
The applicant has mentioned materials such as the protein that utilizes zymotechnic to handle bran coat Testa Tritici or the like biomass to exist, starch in the 4/6th page of ZL03112182.9 description, for example " desire improves the relative amount of its edible fiber class material; need carry out some processing, for example fully rinses on the wheat bran materials such as protein, starch such as gluten cell; And general enzymatic treatment removes materials such as protein, starch, waits its edible fiber class material is increased ".But propose to utilize the cellulose enzyme to handle biomass such as bran coat Testa Tritici, especially propose to utilize the plain enzyme of super fine biological matter powder accessory fibers after the processing of cellulose enzyme processing machine to handle so that powder particle is trickleer, clean and increase the affinity of its dispersibility and raising and barium sulfate powder.
Summary of the invention:
A kind of gastrointestinal contrast agent biotechnology processing method of biomass, it is characterized in that being meant the enzyme processing technology of gastrointestinal contrast agent with the biomass superfines, be in gastrointestinal contrast agent biomass superfines≤100 microns machinings, generally be on the basis of common pulverizing processing equipment manufacturing limit, the auxiliary seriation enzyme that carries out is handled, the particularly processing of cellulose enzyme series, make the surface roughening of biomass superfines, be easy to adsorb inorganic contrast agent ultra-micro powder, be easy to form biomass superfines surface and fully adsorb the complex structure of wrapping up in inorganic contrast agent ultra-micro powders such as band barium sulfate, reach further refinement simultaneously, so that granule is littler, disperse better or the like the advantage of the affinity of better and contrast agent.Generally be the enzyme processing that the cuticular substance in corn or the like source is added biotechnology,
The seriation enzyme is handled and is meant: protease, amylase, lipase, cellulase; Wherein based on cellulase, other enzyme can add and can not add, and can singlely add, and also can compoundly add.
The cellulose enzyme is meant cellulase, hemicellulase, pectase, lignoenzyme or the like, and is single or compound.Advantage: through particularly biotechnology enzyme processing of series of processes, make powdered biomass at the enterprising step refining in ultra-micro powder basis, roughening, easier dispersion, the affinity of raising and contrast agent is wrapped up in the complex structure of being with inorganic contrast agent ultra-micro powders such as barium sulfate thereby be easy to form the abundant absorption in biomass superfines surface; Microwave heating and steaming simultaneously fried and handled, and increases local flavor, reduces undesirable substance.
The specific embodiment:
More than embodiment 1. Testa Tritici, microwave heating to 100 ℃, dry dryly while hot, directly enter next step! Perhaps add pulverizer again and pulverize, make about 104~850 microns of granularities (the granularity specification is with reference to US4774096), carry out the seriation enzyme then and handle (also can be, rather than adopt enzyme process) with reference to the US4774096 Hydrolyze method.(1) amylase is handled: the enzyme that is dissolved in water, fully stir, and adjust PH to 5.5~7 with aqueous hydrochloric acid solution (being not more than 2N), be incubated 78 ℃, 1 hour, clean filter pressing recovery or centrifugal recovery, drying or directly enter next step; (2) Protease Treatment: in order to be fit to the up and down sour environment of flow process, adopt acid protease, PH2.5~4, the suitableeest 3,30~50 ℃ of temperature ranges, about 40 ℃ of optimum temperatures.Adjust PH with aqueous hydrochloric acid solution, be incubated 1 hour, clean, filter pressing is reclaimed or centrifugal recovery, drying, and super micron mill is pulverized to superfines, generally is not more than 100 microns, enters next step; (3) cellulose treatment: the enzyme that is dissolved in water, fully stir, adjust PH to 4~5 with aqueous hydrochloric acid solution (being not more than 2N), be incubated 50 ℃, 0.2~1 hour, microscopy, as seen powder particle emanates, refinement, surperficial roughening, stopped reaction, fully clean centrifugal recovery, drying, packed for standby use.Note grasping the degree that enzyme is handled.
Embodiment 2, and with embodiment 1, difference is that Testa Tritici is transformed to Testa oryzae.
Embodiment 3, and with embodiment 1,2, difference is to heat 100 ℃ or above sterilization processing, and micronizing is a superfines then, generally is not more than 100 microns, and directly cellulose treatment has kept partially protein and starch material.
Embodiment 4, and with embodiment 1,2,3, difference is that Testa Tritici and Testa oryzae are replaced into other biomass material, such as Cortex beans or the like.
Embodiment 5, and with embodiment 1,2,3,4, difference is that microwave heating is replaced into slow fire parch drying.Can reach and improve flavor substance local flavor, the purpose of high temperature sterilization again.
Embodiment 6, and with embodiment 1,2,3,4, difference is that microwave heating is replaced into and steams, and is dry then.Reach and improve flavor substance local flavor, the purpose of high temperature sterilization again.
Embodiment 7, and with embodiment 1, difference is the pectase and 5% hemicellulase of the compound adding 5% of cellulase.
Claims (2)
1. a gastrointestinal contrast agent is with the biotechnology processing method of Testa oryzae or Testa Tritici, it is characterized in that being meant the enzyme processing technology of gastrointestinal contrast agent with Testa oryzae or Testa Tritici superfines, be to adopt protease and amylase to handle the Testa oryzae or the Testa Tritici of 104~850 microns of granularities, drying, super micron mill are pulverized the superfines for≤100 microns, and the plain enzyme of reprocess fibre is handled; Perhaps, directly to machining obtain≤100 microns Testa oryzae or Testa Tritici superfines, carrying out the cellulose enzyme handles, thereby make the surface roughening of Testa oryzae or Testa Tritici superfines, be easy to adsorb inorganic contrast agent ultra-micro powder, be easy to form Testa oryzae or Testa Tritici superfines surface fully absorption wrap up in complex structure with inorganic contrast agent ultra-micro powder, reach simultaneously make that Testa oryzae or Testa Tritici granule diminish, good dispersion, the purpose that improves with the contrast agent affinity.
2. biotechnology processing method as claimed in claim 1 is characterized in that the cellulose enzyme is meant a kind of or its combination in cellulase, hemicellulase, pectase, the lignoenzyme.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CNB2005101045477A CN100356983C (en) | 2005-11-18 | 2005-11-18 | Biotechnological treating method of biomass for stomach intestine contrast-media |
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CNB2005101045477A CN100356983C (en) | 2005-11-18 | 2005-11-18 | Biotechnological treating method of biomass for stomach intestine contrast-media |
Publications (2)
Publication Number | Publication Date |
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CN1814304A CN1814304A (en) | 2006-08-09 |
CN100356983C true CN100356983C (en) | 2007-12-26 |
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CNB2005101045477A Expired - Fee Related CN100356983C (en) | 2005-11-18 | 2005-11-18 | Biotechnological treating method of biomass for stomach intestine contrast-media |
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1278181A (en) * | 1997-08-29 | 2000-12-27 | 里塞克斯股份有限公司 | Method for treating diabetes, hyperglycemia and hypoglycemia |
CN1423532A (en) * | 2000-02-15 | 2003-06-11 | 利波詹尼克斯公司 | Enzymatic processing of rice bran to produce edible products |
CN1444997A (en) * | 2003-04-23 | 2003-10-01 | 山东大学 | Gastrointestinal contrast agent containing biomass |
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2005
- 2005-11-18 CN CNB2005101045477A patent/CN100356983C/en not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1278181A (en) * | 1997-08-29 | 2000-12-27 | 里塞克斯股份有限公司 | Method for treating diabetes, hyperglycemia and hypoglycemia |
CN1423532A (en) * | 2000-02-15 | 2003-06-11 | 利波詹尼克斯公司 | Enzymatic processing of rice bran to produce edible products |
CN1444997A (en) * | 2003-04-23 | 2003-10-01 | 山东大学 | Gastrointestinal contrast agent containing biomass |
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CN1814304A (en) | 2006-08-09 |
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