CN1814090A - Niaoduqing medicine preparation and preparing method - Google Patents
Niaoduqing medicine preparation and preparing method Download PDFInfo
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Abstract
The invention relates to a uremia clearing medicinal preparation prepared of the sixteen traditional Chinese medicines: Rhubarb, Liquorice Root, Chinese Thorowax Root, Membranous Milkvetch Root, Shangqupi, Pilose Asiabell Root, White Paeony Root, Szechuan Lovage Rhizome, Lightyellow Sophora Root, Rhizoma Pinelliae(Processed with Ginger), Chrysanthemun Flower, largehead atractylodes Rhizome, Fuling, Tuber Fleeceflower Root (prepared), Danshen, and Plantain Herb as effective components and the preparing method thereof, especially relating to uremia clearing oral solution and dispersion tablet and the preparing method thereof. The invention spreads the existing uremia clearing tablet to oral solution and dispersion tablet, thus largely raising in-body absorbing rate, raising biological utilization degree, shortening the time for reaching the highest bacteriostasis concentration and making the curative effect more remarkable.
Description
One, technical field:
The present invention relates to a kind of is NIAODUQING pharmaceutical preparation of being prepared from of active component and preparation method thereof with Radix Et Rhizoma Rhei, Radix Glycyrrhizae, Radix Bupleuri, the Radix Astragali, SANGQUPI, Radix Codonopsis, the Radix Paeoniae Alba, Rhizoma Chuanxiong, Radix Sophorae Flavescentis, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Flos Chrysanthemi, the Rhizoma Atractylodis Macrocephalae, Poria, Radix Polygoni Multiflori Preparata, Radix Salviae Miltiorrhizae, Herba Plantaginis 16 flavor Chinese medicines.Relate in particular to NIAODUQING oral liquid and dispersible tablet and preparation method thereof.
Two, background technology:
Urotoxin eliminating tablet is a kind of Chinese medicine, mainly has purging FU-organs the turbid descending, invigorating spleen to remove dampness, function of promoting blood circulation to disperse blood clots.Be used for the treatment of chronic renal failure, azotemia phase and uremia are early stage, Chinese medical discrimination belongs to insufficiency of the spleen turbid damp disease and spleen deficiency and blood stasis disease person.Can reduce creatinine, blood urea nitrogen, stablize renal function, delay dialysis time; To improving renal anemia, increasing blood calcium, reduction serium inorganic phosphorus also have certain effect, and also have clearing away heat-damp and promoting diuresis, promoting blood circulation and stopping pain, fossil, calculus effect.Be mainly used in treatment renal calculus, renal pelvis calculus, vesical calculus, ureteral calculus disease.Taken in state-promulgated pharmacopoeia at present.According to the laws and regulations of the relevant new drug of country, change existing pharmaceutical formulation and promptly belong to the new drug research category.SHENSHITONG CHONGJI is traditional Chinese patent medicine tablet, in order to expand the dosage form of this product, is easy to carry and takes, and satisfies people's medication demand better.The present invention expands as oral liquid and dispersible tablet with NIAODUQING tablet prior dosage form.Make medicine improve greatly like this, improved bioavailability, shortened the highest Mlc time of advent, make the curative effect of medicine more remarkable in the intravital infiltration rate of people.
Three, summary of the invention:
The object of the present invention is to provide a kind of NIAODUQING preparation, specifically, be that active component prepares NIAODUQING oral liquid and dispersible tablet with Radix Et Rhizoma Rhei, Radix Glycyrrhizae, Radix Bupleuri, the Radix Astragali, SANGQUPI, Radix Codonopsis, the Radix Paeoniae Alba, Rhizoma Chuanxiong, Radix Sophorae Flavescentis, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Flos Chrysanthemi, the Rhizoma Atractylodis Macrocephalae, Poria, Radix Polygoni Multiflori Preparata, Radix Salviae Miltiorrhizae, Herba Plantaginis 16 flavor Chinese medicines exactly.
Technical scheme of the present invention is:
A kind of NIAODUQING preparation, it is characterized in that: formulated by the following traditional Chinese medicines component, its composition by weight is: Radix Et Rhizoma Rhei 20-80, Radix Glycyrrhizae 18-72, Radix Bupleuri 30-120, Radix Astragali 80-320, SANGQUPI 60-240, Radix Codonopsis 60-240, Radix Paeoniae Alba 60-240, Rhizoma Chuanxiong 60-240, Radix Sophorae Flavescentis 40-160, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 40-160, Flos Chrysanthemi 50-200, Rhizoma Atractylodis Macrocephalae 100-400, Poria 100-400, Radix Polygoni Multiflori Preparata 100-400, Radix Salviae Miltiorrhizae 100-400, Herba Plantaginis 100-400;
Optimum weight component of the present invention is:
Radix Et Rhizoma Rhei 40, Radix Glycyrrhizae 36, Radix Bupleuri 60, the Radix Astragali 160, SANGQUPI 120, Radix Codonopsis 120, the Radix Paeoniae Alba 120, Rhizoma Chuanxiong 120, Radix Sophorae Flavescentis 80, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 80, Flos Chrysanthemi 100, the Rhizoma Atractylodis Macrocephalae 200, Poria 200, Radix Polygoni Multiflori Preparata 200, Radix Salviae Miltiorrhizae 200, Herba Plantaginis 200.
NIAODUQING preparation of the present invention can be made oral liquid and dispersible tablet.
Its preparation method is:
1, the preparation method of NIAODUQING oral liquid:
A, Radix Et Rhizoma Rhei, Radix Glycyrrhizae, Radix Bupleuri, the Radix Astragali, SANGQUPI, Radix Codonopsis, the Radix Paeoniae Alba, Rhizoma Chuanxiong, Radix Sophorae Flavescentis, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Flos Chrysanthemi, the Rhizoma Atractylodis Macrocephalae, Poria, Radix Polygoni Multiflori Preparata, Radix Salviae Miltiorrhizae, Herba Plantaginis 16 flavor Chinese medicines are cleaned, be up to the standards, standby;
B, get above 16 the flavor Chinese medicines, decoct with water 3 times, the 1st time 4 hours, the 2nd time 3 hours, the 3rd time 3 hours.The 4-12 that decocts amount of water for the 1st time and be Chinese medicine weight doubly, the 4-10 that decocts amount of water for the 2nd time and be Chinese medicine weight doubly, the 6-8 that decocts amount of water for the 3rd time and be Chinese medicine weight is doubly; Collecting decoction filters, and is evaporated to concentrated solution;
C, get concentrated solution and add purified water and correctives, be prepared into oral liquid.
2, NIAODUQING dispersible tablet preparation method:
A, Radix Et Rhizoma Rhei, Radix Glycyrrhizae, Radix Bupleuri, the Radix Astragali, SANGQUPI, Radix Codonopsis, the Radix Paeoniae Alba, Rhizoma Chuanxiong, Radix Sophorae Flavescentis, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Flos Chrysanthemi, the Rhizoma Atractylodis Macrocephalae, Poria, Radix Polygoni Multiflori Preparata, Radix Salviae Miltiorrhizae, Herba Plantaginis 16 flavor Chinese medicines are cleaned, be up to the standards, standby;
B, get above 16 the flavor Chinese medicines, decoct with water the 1st time 4 hours 3 times, the 2nd time 3 hours, the 3rd time 3 hours, the 4-12 that decocts amount of water for the 1st time and be Chinese medicine weight doubly, the 4-10 that decocts amount of water for the 2nd time and be Chinese medicine weight doubly, the 6-8 that decocts amount of water for the 3rd time and be Chinese medicine weight is doubly; Collecting decoction filters, and being evaporated to relative density is the clear paste of 1.20～1.25 (75～80 ℃);
C, with clear paste simmer down to dried cream powder, add an amount of filler and part disintegrating agent, granulate with binding agent or wetting agent, drying, granulate adds disintegrating agent and lubricant again, the mix homogeneously tabletting promptly gets dispersible tablet, makes film-coated dispersion tablet through art for coating again.
Above-mentioned described disintegrating agent is: one or more of crospolyvinylpyrrolidone or Sodium Hydroxymethyl Stalcs or low-substituted hydroxypropyl cellulose or crosslinked Carboxymethyl cellulose sodium.
Binding agent is: one or several of the alcoholic solution of 45-90% or starch slurry or polyvinylpyrrolidone alcoholic solution; The best is the alcoholic solution of 2-4% polyvinylpyrrolidone and 55%.
Lubricant is: magnesium stearate or micropowder silica gel or Pulvis Talci.
Filler is: one or several of starch or lactose or microcrystalline Cellulose or precoking starch.
The advantage of content of the present invention is, overcome the disintegrating procedue of tablet at gastric, be that oral liquid or dispersible tablet all make medicine be absorbed rapidly in the intestines and stomach, make effective ingredient in blood, reach effective Mlc in the short period of time, improved bioavailability, made the product curative effect more remarkable.
Four, the specific embodiment:
Embodiment 1: Radix Et Rhizoma Rhei 40 grams, Radix Glycyrrhizae 36 grams, Radix Bupleuri 60 grams, the Radix Astragali 160 grams, SANGQUPI 120 grams, Radix Codonopsis 120 grams, the Radix Paeoniae Alba 120 grams, Rhizoma Chuanxiong 120 grams, Radix Sophorae Flavescentis 80 grams, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 80 grams, Flos Chrysanthemi 100 grams, the Rhizoma Atractylodis Macrocephalae 200 grams, Poria 200 grams, Radix Polygoni Multiflori Preparata 200 grams, Radix Salviae Miltiorrhizae 200 grams, Herba Plantaginis 200 grams
By the preparation method of NIAODUQING oral liquid in the technique scheme and dispersible tablet, make 10000 milliliters of NIAODUQING oral liquids or 1000 dispersible tablets.
Embodiment 2: Radix Et Rhizoma Rhei 40 grams, Radix Glycyrrhizae 36 grams, Radix Bupleuri 60 grams, the Radix Astragali 160 grams, SANGQUPI 120 grams, Radix Codonopsis 120 grams, the Radix Paeoniae Alba 120 grams, Rhizoma Chuanxiong 120 grams, Radix Sophorae Flavescentis 80 grams, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 80 grams, Flos Chrysanthemi 100 grams, the Rhizoma Atractylodis Macrocephalae 200 grams, Poria 200 grams, Radix Polygoni Multiflori Preparata 200 grams, Radix Salviae Miltiorrhizae 200 grams, Herba Plantaginis 200 grams
By the preparation method of NIAODUQING oral liquid in the technique scheme and dispersible tablet, make 5000 milliliters of NIAODUQING oral liquids or 500 dispersible tablets.
Embodiment 3: Radix Et Rhizoma Rhei 40 grams, Radix Glycyrrhizae 36 grams, Radix Bupleuri 60 grams, the Radix Astragali 160 grams, SANGQUPI 120 grams, Radix Codonopsis 120 grams, the Radix Paeoniae Alba 120 grams, Rhizoma Chuanxiong 120 grams, Radix Sophorae Flavescentis 80 grams, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 80 grams, Flos Chrysanthemi 100 grams, the Rhizoma Atractylodis Macrocephalae 200 grams, Poria 200 grams, Radix Polygoni Multiflori Preparata 200 grams, Radix Salviae Miltiorrhizae 200 grams, Herba Plantaginis 200 grams
By the preparation method of NIAODUQING oral liquid in the technique scheme and dispersible tablet, make 2500 milliliters of NIAODUQING oral liquids or 250 dispersible tablets.
Embodiment 4: Radix Et Rhizoma Rhei 40 grams, Radix Glycyrrhizae 36 grams, Radix Bupleuri 60 grams, the Radix Astragali 160 grams, SANGQUPI 120 grams, Radix Codonopsis 120 grams, the Radix Paeoniae Alba 120 grams, Rhizoma Chuanxiong 120 grams, Radix Sophorae Flavescentis 80 grams, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 80 grams, Flos Chrysanthemi 100 grams, the Rhizoma Atractylodis Macrocephalae 200 grams, Poria 200 grams, Radix Polygoni Multiflori Preparata 200 grams, Radix Salviae Miltiorrhizae 200 grams, Herba Plantaginis 200 grams
By the preparation method of NIAODUQING oral liquid in the technique scheme and dispersible tablet, make 20000 milliliters of NIAODUQING oral liquids or 2000 dispersible tablets.
Embodiment 5: Radix Et Rhizoma Rhei 40 grams, Radix Glycyrrhizae 36 grams, Radix Bupleuri 60 grams, the Radix Astragali 160 grams, SANGQUPI 120 grams, Radix Codonopsis 120 grams, the Radix Paeoniae Alba 120 grams, Rhizoma Chuanxiong 120 grams, Radix Sophorae Flavescentis 80 grams, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 80 grams, Flos Chrysanthemi 100 grams, the Rhizoma Atractylodis Macrocephalae 200 grams, Poria 200 grams, Radix Polygoni Multiflori Preparata 200 grams, Radix Salviae Miltiorrhizae 200 grams, Herba Plantaginis 200 grams
By the preparation method of NIAODUQING oral liquid in the technique scheme and dispersible tablet, make 40000 milliliters of NIAODUQING oral liquids or 4000 dispersible tablets.
Embodiment 6: Radix Et Rhizoma Rhei 80 grams, Radix Glycyrrhizae 72 grams, Radix Bupleuri 120 grams, the Radix Astragali 320 grams, SANGQUPI 240 grams, Radix Codonopsis 240 grams, the Radix Paeoniae Alba 240 grams, Rhizoma Chuanxiong 240 grams, Radix Sophorae Flavescentis 160 grams, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 160 grams, Flos Chrysanthemi 200 grams, the Rhizoma Atractylodis Macrocephalae 400 grams, Poria 400 grams, Radix Polygoni Multiflori Preparata 400 grams, Radix Salviae Miltiorrhizae 400 grams, Herba Plantaginis 400 grams
By the preparation method of NIAODUQING oral liquid in the technique scheme and dispersible tablet, make 10000 milliliters of NIAODUQING oral liquids or 1000 dispersible tablets.
Embodiment 7: Radix Et Rhizoma Rhei 80 grams, Radix Glycyrrhizae 72 grams, Radix Bupleuri 120 grams, the Radix Astragali 320 grams, SANGQUPI 240 grams, Radix Codonopsis 240 grams, the Radix Paeoniae Alba 240 grams, Rhizoma Chuanxiong 240 grams, Radix Sophorae Flavescentis 160 grams, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 160 grams, Flos Chrysanthemi 200 grams, the Rhizoma Atractylodis Macrocephalae 400 grams, Poria 400 grams, Radix Polygoni Multiflori Preparata 400 grams, Radix Salviae Miltiorrhizae 400 grams, Herba Plantaginis 400 grams
By the preparation method of NIAODUQING oral liquid in the technique scheme and dispersible tablet, make 5000 milliliters of NIAODUQING oral liquids or 500 dispersible tablets.
Embodiment 8: Radix Et Rhizoma Rhei 80 grams, Radix Glycyrrhizae 72 grams, Radix Bupleuri 120 grams, the Radix Astragali 320 grams, SANGQUPI 240 grams, Radix Codonopsis 240 grams, the Radix Paeoniae Alba 240 grams, Rhizoma Chuanxiong 240 grams, Radix Sophorae Flavescentis 160 grams, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 160 grams, Flos Chrysanthemi 200 grams, the Rhizoma Atractylodis Macrocephalae 400 grams, Poria 400 grams, Radix Polygoni Multiflori Preparata 400 grams, Radix Salviae Miltiorrhizae 400 grams, Herba Plantaginis 400 grams
By the preparation method of NIAODUQING oral liquid in the technique scheme and dispersible tablet, make 2500 milliliters of NIAODUQING oral liquids or 250 dispersible tablets.
Embodiment 9: Radix Et Rhizoma Rhei 80 grams, Radix Glycyrrhizae 72 grams, Radix Bupleuri 120 grams, the Radix Astragali 320 grams, SANGQUPI 240 grams, Radix Codonopsis 240 grams, the Radix Paeoniae Alba 240 grams, Rhizoma Chuanxiong 240 grams, Radix Sophorae Flavescentis 160 grams, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 160 grams, Flos Chrysanthemi 200 grams, the Rhizoma Atractylodis Macrocephalae 400 grams, Poria 400 grams, Radix Polygoni Multiflori Preparata 400 grams, Radix Salviae Miltiorrhizae 400 grams, Herba Plantaginis 400 grams
By the preparation method of NIAODUQING oral liquid in the technique scheme and dispersible tablet, make 20000 milliliters of NIAODUQING oral liquids or 2000 dispersible tablets.
Embodiment 10, Radix Et Rhizoma Rhei 80 grams, Radix Glycyrrhizae 72 grams, Radix Bupleuri 120 grams, the Radix Astragali 320 grams, SANGQUPI 240 grams, Radix Codonopsis 240 grams, the Radix Paeoniae Alba 240 grams, Rhizoma Chuanxiong 240 grams, Radix Sophorae Flavescentis 160 grams, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 160 grams, Flos Chrysanthemi 200 grams, the Rhizoma Atractylodis Macrocephalae 400 grams, Poria 400 grams, Radix Polygoni Multiflori Preparata 400 grams, Radix Salviae Miltiorrhizae 400 grams, Herba Plantaginis 400 grams
By the preparation method of NIAODUQING oral liquid in the technique scheme and dispersible tablet, make 30000 milliliters of NIAODUQING oral liquids or 3000 dispersible tablets.
Embodiment 11, Radix Et Rhizoma Rhei 80 grams, Radix Glycyrrhizae 72 grams, Radix Bupleuri 120 grams, the Radix Astragali 320 grams, SANGQUPI 240 grams, Radix Codonopsis 240 grams, the Radix Paeoniae Alba 240 grams, Rhizoma Chuanxiong 240 grams, Radix Sophorae Flavescentis 160 grams, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 160 grams, Flos Chrysanthemi 200 grams, the Rhizoma Atractylodis Macrocephalae 400 grams, Poria 400 grams, Radix Polygoni Multiflori Preparata 400 grams, Radix Salviae Miltiorrhizae 400 grams, Herba Plantaginis 400 grams
By the preparation method of NIAODUQING oral liquid in the technique scheme and dispersible tablet, make 40000 milliliters of NIAODUQING oral liquids or 4000 dispersible tablets.
Claims (7)
1, a kind of NIAODUQING pharmaceutical preparation and preparation method thereof, its NIAODUQING pharmaceutical preparation is meant NIAODUQING oral liquid or NIAODUQING dispersible tablet, it is characterized in that: formulated by the following traditional Chinese medicines component, its composition by weight is: Radix Et Rhizoma Rhei 20-80, Radix Glycyrrhizae 18-72, Radix Bupleuri 30-120, Radix Astragali 80-320, SANGQUPI 60-240, Radix Codonopsis 60-240, Radix Paeoniae Alba 60-240, Rhizoma Chuanxiong 60-240, Radix Sophorae Flavescentis 40-160, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 40-160, Flos Chrysanthemi 50-200, Rhizoma Atractylodis Macrocephalae 100-400, Poria 100-400, Radix Polygoni Multiflori Preparata 100-400, Radix Salviae Miltiorrhizae 100-400, Herba Plantaginis 100-400;
Optimum weight component is:
Radix Et Rhizoma Rhei 40, Radix Glycyrrhizae 36, Radix Bupleuri 60, the Radix Astragali 160, SANGQUPI 120, Radix Codonopsis 120, the Radix Paeoniae Alba 120, Rhizoma Chuanxiong 120, Radix Sophorae Flavescentis 80, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 80, Flos Chrysanthemi 100, the Rhizoma Atractylodis Macrocephalae 200, Poria 200, Radix Polygoni Multiflori Preparata 200, Radix Salviae Miltiorrhizae 200, Herba Plantaginis 200.
2, NIAODUQING pharmaceutical preparation according to claim 1 and preparation method, it is characterized in that: the preparation method of NIAODUQING oral liquid is:
A, Radix Et Rhizoma Rhei, Radix Glycyrrhizae, Radix Bupleuri, the Radix Astragali, SANGQUPI, Radix Codonopsis, the Radix Paeoniae Alba, Rhizoma Chuanxiong, Radix Sophorae Flavescentis, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Flos Chrysanthemi, the Rhizoma Atractylodis Macrocephalae, Poria, Radix Polygoni Multiflori Preparata, Radix Salviae Miltiorrhizae, Herba Plantaginis 16 flavor Chinese medicines are cleaned, be up to the standards, standby;
B, get above 16 the flavor Chinese medicines, decoct with water the 1st time 4 hours 3 times, the 2nd time 3 hours, the 3rd time 3 hours, the 4-12 that decocts amount of water for the 1st time and be Chinese medicine weight doubly, the 4-10 that decocts amount of water for the 2nd time and be Chinese medicine weight doubly, the 6-8 that decocts amount of water for the 3rd time and be Chinese medicine weight is doubly; Collecting decoction filters, and is evaporated to concentrated solution;
C, get concentrated solution and add purified water and correctives, be prepared into oral liquid.
3, NIAODUQING pharmaceutical preparation according to claim 1 and preparation method, it is characterized in that: the preparation method of NIAODUQING dispersible tablet is:
A, Radix Et Rhizoma Rhei, Radix Glycyrrhizae, Radix Bupleuri, the Radix Astragali, SANGQUPI, Radix Codonopsis, the Radix Paeoniae Alba, Rhizoma Chuanxiong, Radix Sophorae Flavescentis, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Flos Chrysanthemi, the Rhizoma Atractylodis Macrocephalae, Poria, Radix Polygoni Multiflori Preparata, Radix Salviae Miltiorrhizae, Herba Plantaginis 16 flavor Chinese medicines are cleaned, be up to the standards, standby;
B, get above 16 the flavor Chinese medicines, decoct with water the 1st time 4 hours 3 times, the 2nd time 3 hours, the 3rd time 3 hours, the 4-12 that decocts amount of water for the 1st time and be Chinese medicine weight doubly, the 4-10 that decocts amount of water for the 2nd time and be Chinese medicine weight doubly, the 6-8 that decocts amount of water for the 3rd time and be Chinese medicine weight is doubly; Collecting decoction filters, and being evaporated to relative density is the clear paste of 1.20～1.25 (75～80 ℃);
C, with clear paste simmer down to dried cream powder, add an amount of filler and part disintegrating agent, granulate with binding agent or wetting agent, drying, granulate adds disintegrating agent and lubricant again, the mix homogeneously tabletting promptly gets dispersible tablet, makes film-coated dispersion tablet through art for coating again.
4, NIAODUQING pharmaceutical preparation according to claim 3 and preparation method, it is characterized in that: disintegrating agent is: one or more of crospolyvinylpyrrolidone or Sodium Hydroxymethyl Stalcs or low-substituted hydroxypropyl cellulose or crosslinked Carboxymethyl cellulose sodium.
5, NIAODUQING pharmaceutical preparation according to claim 3 and preparation method, it is characterized in that: binding agent is: one or several of the alcoholic solution of 45-90% or starch slurry or polyvinylpyrrolidone alcoholic solution; The best is the alcoholic solution of 2-4% polyvinylpyrrolidone and 55%.
6, NIAODUQING pharmaceutical preparation according to claim 3 and preparation method, it is characterized in that: lubricant is: magnesium stearate or micropowder silica gel or Pulvis Talci.
7, NIAODUQING pharmaceutical preparation according to claim 3 and preparation method, it is characterized in that: filler is: one or several of starch or lactose or microcrystalline Cellulose or precoking starch.
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| CN 200510032479 CN1814090A (en) | 2005-11-24 | 2005-11-24 | Niaoduqing medicine preparation and preparing method |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103446558A (en) * | 2013-07-26 | 2013-12-18 | 杨德俊 | Traditional Chinese medicine for treating chronic nephritis |
| CN109464606A (en) * | 2019-01-02 | 2019-03-15 | 李文元 | A kind of Chinese medicine composition for treating hypertensin urine |
-
2005
- 2005-11-24 CN CN 200510032479 patent/CN1814090A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103446558A (en) * | 2013-07-26 | 2013-12-18 | 杨德俊 | Traditional Chinese medicine for treating chronic nephritis |
| CN103446558B (en) * | 2013-07-26 | 2015-09-23 | 杨德俊 | A kind of Chinese medicine for the treatment of chronic nephritis |
| CN109464606A (en) * | 2019-01-02 | 2019-03-15 | 李文元 | A kind of Chinese medicine composition for treating hypertensin urine |
| CN109464606B (en) * | 2019-01-02 | 2021-06-25 | 李文元 | Traditional Chinese medicine composition for treating hypertensive proteinuria |
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Open date: 20060809 |