CN1742950A - Chinese medicine preparation made from corn stigma and preparing method - Google Patents
Chinese medicine preparation made from corn stigma and preparing method Download PDFInfo
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- CN1742950A CN1742950A CN 200410011071 CN200410011071A CN1742950A CN 1742950 A CN1742950 A CN 1742950A CN 200410011071 CN200410011071 CN 200410011071 CN 200410011071 A CN200410011071 A CN 200410011071A CN 1742950 A CN1742950 A CN 1742950A
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- stigma maydis
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Abstract
The present invention discloses a new type Chinese medicine oral preparation for curing diabetes, raising immunity of body and resisting tumor. It is made up by using corn silk as raw material, and can be made into different oral dosage forms.
Description
Technical field:
The present invention relates to field of traditional Chinese, more particularly relating to Chinese medicine Stigma Maydis and other Chinese herbal medicine is feedstock production different dosage form product and production method thereof.
Technical background:
Stigma Maydis is zeistic style of grass family annual herb plant and stigma, and the property slightly sweet flavor is flat, goes into bladder, gallbladder meridian.Says in " modern practical Chinese medicine ": Stigma Maydis is a diuretic, and is effective to nephropathy, edema illness, diabetes, is the active drug of diseases such as treatment cholecystitis, cholelithiasis, hepatitis jaundice again.Be a kind of easily available, cheap and good-quality good medicine.Pharmacological research shows that Stigma Maydis all has diuresis to people or rabbit, can increase the chloride output, but a little less than the effect.Stigma Maydis still can promote bile excretion, reduce its viscosity, reduce bile pigments content, can be used as choleretic and be used for the cholangitis patient that uncomplicated chronic cholecystitis, bile are discharged obstacle, can also the accelerate blood process of setting, strengthen the content of thrombin in the blood, improve platelet count, be applied to bladder and lithangiuria so can be used as the hemorrhage diuretic of holding concurrently.The fermentation preparation of Stigma Maydis has the effect of the blood sugar lowering of highly significant to rabbit, and can anti-hemolysis, antiallergic and detoxifcation.Clinical experience proves that by caused edema of nephropathy and hypertension, effect is obviously stablized with the Stigma Maydis treatment.
Malignant tumor often claims cancer, is commonly encountered diseases, the frequently-occurring disease of one group of serious threat human health.The method of treatment malignant tumor comprises surgical operation, radiotherapy and chemotherapy (abbreviation chemotherapy).Chemotherapy is emphasized systemic treatment and is different from surgical operation and the radiotherapy that is fit to the local tumor treatment.
Since nineteen forty-three Gilman etc. at first is applied to chlormethine lymphadenomatous treatment, opened since the prelude of modern chemotherapy of tumors, the basis and the clinical research of anti-malignant-tumor agent (antineoplasticdrugs) make great progress, chemotherapy strides forward to the radical-ability target from appeasing property target, and about 5% malignant tumor might obtain curing by chemotherapy.Yet the treatment that accounts for the solid tumor of malignant tumor more than 90% but fails to reach satisfied effect.Mainly there are two big obstacles in chemotherapy of tumors: one, the toxic reaction of anti-malignant tumor medicine.The conventional cell of clinical use now poison class anti-malignant tumor medicine is not strong to the selectivity of tumor cell, in killing tumor cell, normal histiocyte is also had in various degree damage.The limited key factor of drug dose when the mouldiness reaction becomes chemotherapy.Its two, tumor cell produces drug resistance.In the chemotherapy process, it is drug resistance that tumor cell produces insensitive phenomenon to anti-malignant tumor medicine, is the major reason of chemotherapy of tumors failure, also is the difficult problem that chemotherapy of tumors is badly in need of solution.
In recent years, the development of biological progress of cellular elements and tumor pharmacology, for the medical treatment of malignant tumor provides many novel targets, anti-malignant-tumor agent just from traditional cytotoxic drug to novel anti malignant tumor medicine development, as tumor cell induction differentiation agent, apoptosis of tumor cells (apoptosis) derivant, antineoplastic invasion and shift medicine, new vessels formation inhibitor, drug resistance of tumor inversion agent and therapy of tumor etc. at the too many levels effect of mechanism.
Summary of the invention:
Purpose of the present invention is exactly to carry out the exploitation of Stigma Maydis, with the Stigma Maydis is raw material, by certain processing method, make different dosage form products, and have the medical function that treatment diabetes and human body immunity improving are resisted tumor strenuously through the medicine of the processing and preparing of the inventive method.
Therefore, another object of the present invention is a raw material with the Stigma Maydis exactly, cooperates other Chinese herbal medicine, prepares a kind of treatment diabetes and human body immunity improving power anti-tumor drug.
The technical solution used in the present invention:
One. raw material processing
1. clean: at rural area purchase Stigma Maydis sample, clean, dry.
2, baked coke is pulverized: above-mentioned Stigma Maydis dry product, put into electric baking oven, and temperature is controlled at below 100 ℃, is baked to dry baked coke, and general stoving time was put into pulverizer with the dry product of baking then between 1-2 hour, pulverize.
Two, preparation Stigma Maydis concentrated juice:
The Stigma Maydis baked coke product of pulverizing are added water, heated and boiled, amount of water did not have medical material to be advisable with the water surface in container, boiled 1-3 hour, the gained medicinal liquid was concentrated into contain crude drug 70%, then with the canned after filtering cryopreservation of natural juice.This concentrated juice is the raw material of following products.
The preparation of above-mentioned concentrated juice can be carried out in vacuum concentration pan.Can be the direct decocting in water of raw material with the bright product of Stigma Maydis during the preparation concentrated juice, concentrate.
Three., spray drying, encapsulated:
Concentrated juice is carried out spray drying through spray drying tower, and use air-flowing type shower nozzle according to the spray drying process of routine drying time, and air pressure is generally 28-57 * 10
4Pa.Exsiccant powder is encapsulated, promptly get product.
In above-mentioned capsular preparation process, can also add the Chinese medicine Radix Trichosanthis.The amount that adds Radix Trichosanthis is Stigma Maydis by weight: Radix Trichosanthis is 1-5: 5-1, the adding of Radix Trichosanthis can be before concentrating with Stigma Maydis with raw material mode input, decocting in water.Also can be that Radix Trichosanthis is made fine powder, drying be crossed sieve No. six, presses the medicated powder of Stigma Maydis concentrated juice spray drying gained powder and Radix Trichosanthis after the said mixed encapsulated.
Four, preparation Stigma Maydis electuary (also being referred to as the Stigma Maydis crystalline substance)
Step (three) gained Stigma Maydis concentrated juice is carried out spray drying as stated above make xeraphium.
Get Fructus Hordei Vulgaris and bake, baking temperature is between 80-120 ℃, and the time is 1-3 hour, and it is standby to wear into fine powder then.
Getting coffee bean processing, to wear into fine powder standby.
The dry powder that the Stigma Maydis concentrated juice is made, Fructus Hordei Vulgaris powder, coffee bean powder, stevioside are according to following mixed then.
Stigma Maydis xeraphium 20-40%
Fructus Hordei Vulgaris powder 30-45%
Coffee bean powder 1-10%
Stevioside 5-15%
Said mixture is dropped into packing machine, dress up moisture barrier bag, adorn 12 grams only for every bag, then with packed one-tenth box, packing is dispatched from the factory.
Above-mentioned electuary can also add Semen sojae atricolor powder, perhaps glucose (adding glucose when making common beverages).
Five, preparation corn stigma juice
Depend on that earlier pine torch decocts with water, amount of water did not have powder to be advisable with water, generally decocted 30-90 minute, the gained medicinal liquid was concentrated into contain crude drug 70%.
Get the Stigma Maydis concentrated juice of preparation in the step (three), press 5-1 with the Semen Cassiae concentrated solution: the 1-5 mixed, be diluted to 10%-15% with mineral water (disinfectant) then, add stevioside again, its content is generally at 1-10%.
The gained mixed liquor is dropped into dispensing apparatus packing, preparing product.
Six, preparation Stigma Maydis medicated tea
Get Stigma Maydis and clean, put into baking box 100-120 ℃ of baking 1-2 hour, be slight coke yellow to Stigma Maydis, pulverized the 20-50 mesh sieve, make into fine particulate, standby.
Get oolong tea and pulverize, cross the 20-50 mesh sieve, become fine particulate, standby.
Stigma Maydis granule and oolong tea granule in the ratio mixing of 5-1: 1-5, are distributed into the teabag pouch, whenever attack 6g again with the moisture barrier bag outer package.
Stigma Maydis is not used by extensive exploitation always, few people with it as medicinal.Characteristics of the present invention are exactly the product that development and use Stigma Maydis feedstock production becomes different dosage form, promptly can also can be used as Medicines and Health Product and use as medicinal.The treatment diabetes that product of the present invention rose, Stigma Maydis possessed human body immunity improving power antineoplastic action just.This also provides a kind of new medicine for diabetics, tumor patient.
Embodiment 1
Get the Stigma Maydis dry product and clean, oven for baking, temperature were toasted 1-2 hour below 100 ℃, took out and pulverized, and added water boil 1 hour, and amount of water was not advisable to have medical material, and special medicinal liquid is concentrated into 70%.Get the Stigma Maydis concentrated solution.Go into spray drying tower then and carry out spray drying, use the air-flowing type shower nozzle, air pressure is generally 3-6 * 10
5Pa.
Embodiment 2
With Stigma Maydis powder and Radix Trichosanthis mixed, encapsulated with 5: 1.
Embodiment 3
With Stigma Maydis powder 45%, Fructus Hordei Vulgaris powder 40%, coffee bean powder 10%, stevioside 5% mixes, and makes Stigma Maydis and dashes example;
Embodiment 4
Get Stigma Maydis and clean, in the baking box 120 ℃ of bakings 60 minutes sad, be slight coke yellow to Stigma Maydis, pulverized 20 order scalpings, make into fine particulate.Get oolong tea again and pulverize, cross 20 order scalpings, become fine particulate.Then with 2 parts of Stigma Maydis dry products, 1 part of oolong tea granule, mixing is distributed into the teabag pouch, and every bag of 6g is again with the moisture barrier bag outer package.
Above embodiment is only for the present invention is further illustrated, and scope of the present invention is not subjected to the limitation of illustrated embodiment.
Claims (5)
1, a kind of treatment diabetes, human body immunity improving power antitumor medicine composition is characterized in that it is made up of Stigma Maydis dry powder and Radix Trichosanthis, and their weight ratio is (1-5): (5-1).
2, the preparation method of the described medicine capsule of claim 1 is characterized in that just Stigma Maydis dry powder decocting in water, and decocting liquid concentrates, with the concentrated solution spraying drying powder-forming, again Radix Trichosanthis is ground into fine powder, then with (1-5): weight ratio (5-1) is mixed Stigma Maydis dry powder and Radix Trichosanthis, and is encapsulated.
3, a kind of is that primary raw material is formed electuary by Stigma Maydis, it is characterized in that it is made up of following component:
Stigma Maydis xeraphium 20-40%
Fructus Hordei Vulgaris powder 30-45%
Coffee bean powder 1-10%
Stevioside 5-15%
4, electuary as claimed in claim 3, Stigma Maydis xeraphium wherein are the xeraphiums that is made by Stigma Maydis water cooking liquid spray drying.
5, a kind of is the oral liquid of primary raw material preparation by Stigma Maydis, it is characterized in that it is made up of Stigma Maydis decocting liquid, Rhizoma amorphophalli (Konjac) decocting liquid, water and stevioside, wherein Stigma Maydis and Rhizoma amorphophalli amount ratio are (1-5): (5-1), the two crude drug total content in oral liquid is 10-20%, stevioside content is 1-10%, water surplus.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410011071 CN1742950A (en) | 2004-09-01 | 2004-09-01 | Chinese medicine preparation made from corn stigma and preparing method |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410011071 CN1742950A (en) | 2004-09-01 | 2004-09-01 | Chinese medicine preparation made from corn stigma and preparing method |
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| Publication Number | Publication Date |
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| CN1742950A true CN1742950A (en) | 2006-03-08 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 200410011071 Pending CN1742950A (en) | 2004-09-01 | 2004-09-01 | Chinese medicine preparation made from corn stigma and preparing method |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101946944A (en) * | 2010-08-18 | 2011-01-19 | 齐齐哈尔医学院 | Corn silk water and preparation method thereof |
| CN101263900B (en) * | 2008-04-24 | 2012-01-11 | 吉林大学 | Preparation of corn filament soft capsule |
| CN102094044B (en) * | 2009-12-14 | 2012-08-22 | 深圳波顿香料有限公司 | Method for preparing corn stigma extract, extract and using method of extract |
| CN104054859A (en) * | 2013-03-19 | 2014-09-24 | 洛阳春魁农业开发有限公司 | Preparation method of corn silk instant health-care tea |
| CN104055179A (en) * | 2013-03-19 | 2014-09-24 | 洛阳春魁农业开发有限公司 | Preparation method of corn silk extract drink |
| CN105394267A (en) * | 2015-11-10 | 2016-03-16 | 王云 | Blood-pressure-lowering and blood-sugar-lowering tea and application thereof |
| CN111714592A (en) * | 2020-07-14 | 2020-09-29 | 张继 | A Chinese medicinal composition for treating diabetes, and its preparation method |
-
2004
- 2004-09-01 CN CN 200410011071 patent/CN1742950A/en active Pending
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101263900B (en) * | 2008-04-24 | 2012-01-11 | 吉林大学 | Preparation of corn filament soft capsule |
| CN102094044B (en) * | 2009-12-14 | 2012-08-22 | 深圳波顿香料有限公司 | Method for preparing corn stigma extract, extract and using method of extract |
| CN101946944A (en) * | 2010-08-18 | 2011-01-19 | 齐齐哈尔医学院 | Corn silk water and preparation method thereof |
| CN101946944B (en) * | 2010-08-18 | 2012-10-17 | 齐齐哈尔医学院 | Corn silk water and preparation method thereof |
| CN104054859A (en) * | 2013-03-19 | 2014-09-24 | 洛阳春魁农业开发有限公司 | Preparation method of corn silk instant health-care tea |
| CN104055179A (en) * | 2013-03-19 | 2014-09-24 | 洛阳春魁农业开发有限公司 | Preparation method of corn silk extract drink |
| CN105394267A (en) * | 2015-11-10 | 2016-03-16 | 王云 | Blood-pressure-lowering and blood-sugar-lowering tea and application thereof |
| CN111714592A (en) * | 2020-07-14 | 2020-09-29 | 张继 | A Chinese medicinal composition for treating diabetes, and its preparation method |
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