CN1730037A - Process for preparing thrombus eliminating dripping pills - Google Patents
Process for preparing thrombus eliminating dripping pills Download PDFInfo
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- CN1730037A CN1730037A CN 200510088076 CN200510088076A CN1730037A CN 1730037 A CN1730037 A CN 1730037A CN 200510088076 CN200510088076 CN 200510088076 CN 200510088076 A CN200510088076 A CN 200510088076A CN 1730037 A CN1730037 A CN 1730037A
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Abstract
The invention belongs to the field of pharmacy, more specifically a process for preparing drop pills for treating cerebral thrombosis by using crude drugs according to the prescription through conventional methods. The drop pills can treat diseases caused by apoplexy.
Description
One, technical field:
The invention belongs to the medical science technical field of Chinese patent medicine, relate to a kind of method for making of thrombus dispelling pill specifically.
Two, background technology:
Common the having of medicine " embolism extinguishing oral liquid " of treatment inrigorating qi and promoting blood circulation collateral dredging commonly used in the market, embolism extinguishing oral liquid " 10ml, took 30ml on 1st, dose is big, carries inconvenience, contains sucrose, is not suitable for diabetic to take.
Three, summary of the invention:
Purpose of the present invention is with the prescription medical material of " embolism extinguishing oral liquid ", and the thrombus dispelling pill a kind of easy to carry that adopts specific method for making to make is to overcome above-mentioned deficiency.
The objective of the invention is to realize by following technical scheme:
A kind of method for making of thrombus dispelling pill, prescription derives from " embolism extinguishing oral liquid ", and be characterized in: thrombus dispelling pill is in process of production, get the Radix Astragali, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Pheretima, Rhizoma Chuanxiong, Semen Persicae, flos carthami decocts with water three times, and 1.5 hours for the first time, second and third time was respectively 1 hour, collecting decoction, filter, it is 1.18～1.22,50 ℃ that filtrate decompression is concentrated into relative density, adds ethanol and makes that to contain the alcohol amount be 75%, leave standstill, get supernatant, reclaim ethanol, medicinal liquid concentrates, dry, be ground into fine powder, add Polyethylene Glycol, make drop pill;
Thrombus dispelling pill is got the Radix Astragali in process of production, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Pheretima, Rhizoma Chuanxiong, Semen Persicae, flos carthami decoct with water three times, add 8 times of amounts of water for the first time, decocted 1.5 hours, second and third time adds 6 times of amounts of water respectively, decocts respectively 1 hour, collecting decoction, filter, it is 1.18～1.22,50 ℃ that filtrate decompression is concentrated into relative density, adds ethanol and makes that to contain the alcohol amount be 75%, leave standstill, get supernatant, reclaim ethanol, medicinal liquid concentrates, dry, be ground into fine powder, add polyethylene glycol 6000 and Macrogol 4000, make drop pill;
Thrombus dispelling pill is got the Radix Astragali in process of production, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Pheretima, Rhizoma Chuanxiong, Semen Persicae, flos carthami decoct with water three times, add 10 times of amounts of water for the first time, decocted 1.5 hours, second and third time adds 8 times of amounts of water respectively, decocts collecting decoction respectively 1 hour, filter, it is 1.18～1.22,50 ℃ that filtrate decompression is concentrated into relative density, adds ethanol and makes that to contain the alcohol amount be 75%, leaves standstill, get supernatant, reclaim ethanol, medicinal liquid concentrates, drying, be ground into fine powder, add polyethylene glycol 6000, make drop pill, promptly;
Thrombus dispelling pill is got the Radix Astragali in process of production, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Pheretima, Rhizoma Chuanxiong, Semen Persicae, flos carthami decoct with water three times, add 8 times of amounts of water for the first time, decocted 1.5 hours, second and third time adds 8 times of amounts of water respectively, decocts collecting decoction respectively 1 hour, filter, it is 1.18～1.22,50 ℃ that filtrate decompression is concentrated into relative density, add ethanol makes that to contain alcohol amount be 75%, leaves standstill, and gets supernatant, reclaim ethanol, medicinal liquid concentrates, and drying is ground into fine powder, adding, ethylene glycol 4000 and Macrogol 600 are made drop pill;
Thrombus dispelling pill is got the Radix Astragali in process of production, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Pheretima, Rhizoma Chuanxiong, Semen Persicae, flos carthami decoct with water three times, add 6 times of amounts of water for the first time, decocted 1.5 hours, second and third time adds 6 times of amounts of water respectively, decocts collecting decoction respectively 1 hour, filter, it is 1.18～1.22,50 ℃ that filtrate decompression is concentrated into relative density, add ethanol makes that to contain alcohol amount be 75%, leaves standstill, and gets supernatant, reclaim ethanol, medicinal liquid concentrates, and drying is ground into fine powder, add Polyethylene Glycol 8000 and PEG400, make drop pill.
The invention discloses a kind of method for making of inrigorating qi and promoting blood circulation collateral dredging thrombus dispelling pill, thrombus dispelling pill is used for wind-induced hemiplegia, facial hemiparalysis, and aphasia, slobbering, the lower limb fistula is useless, frequent micturition.Thrombus dispelling pill is with specific prepared, and it is little, easy to carry to have a dose, and the adjuvant sugar-free is convenient to the characteristics of diabetic to take.
Four, the specific embodiment:
The thrombus dispelling pill prescription is as follows:
Radix Astragali 600g, Radix Angelicae Sinensis 60g, Radix Paeoniae Rubra 60g, Pheretima 30g, Rhizoma Chuanxiong 30g, Semen Persicae 30g, Flos Carthami 30g
Thrombus dispelling pill adopts following method for making:
Get above seven flavor medicine material, Radix Astragali 600g, Radix Angelicae Sinensis 60g, Radix Paeoniae Rubra 60g, Pheretima 30g, Rhizoma Chuanxiong 30g, Semen Persicae 30g, Flos Carthami 30g, decoct with water three times, 1.5 hours for the first time, second and third time was respectively 1 hour, collecting decoction, filter, it is 1.18～1.22,50 ℃ that filtrate decompression is concentrated into relative density, adds ethanol and makes that to contain the alcohol amount be 75%, leaves standstill, get supernatant, reclaim ethanol, medicinal liquid concentrates, drying, be ground into fine powder, add Polyethylene Glycol, make drop pill.Once take 1.5g, took 4.5g on the 1st.
Embodiment one
Get above seven flavor medicine material, Radix Astragali 600g, Radix Angelicae Sinensis 60g, Radix Paeoniae Rubra 60g, Pheretima 30g, Rhizoma Chuanxiong 30g, Semen Persicae 30g, Flos Carthami 30g decocts with water three times, for the first time add 8 times of amounts of water, decocted 1.5 hours, second and third time adds 6 times of amounts of water respectively, decocted respectively 1 hour, collecting decoction filters, it is 1.18～1.22,50 ℃ that filtrate decompression is concentrated into relative density, adds ethanol and makes that to contain alcohol amount be 75%, leaves standstill, get supernatant, reclaim ethanol, medicinal liquid concentrates, drying, be ground into fine powder, add polyethylene glycol 6000 and Macrogol 4000, make drop pill, promptly.
Embodiment two
Get above seven flavor medicine material, Radix Astragali 600g, Radix Angelicae Sinensis 60g, Radix Paeoniae Rubra 60g, Pheretima 30g, Rhizoma Chuanxiong 30g, Semen Persicae 30g, Flos Carthami 30g decocts with water three times, for the first time add 10 times of amounts of water, decocted 1.5 hours, second and third time adds 8 times of amounts of water respectively, decocted respectively 1 hour, collecting decoction filters, it is 1.18～1.22,50 ℃ that filtrate decompression is concentrated into relative density, adds ethanol and makes that to contain alcohol amount be 75%, leaves standstill, get supernatant, reclaim ethanol, medicinal liquid concentrates, drying, be ground into fine powder, add polyethylene glycol 6000, make drop pill, promptly.
Embodiment three
Get above seven flavor medicine material, Radix Astragali 600g, Radix Angelicae Sinensis 60g, Radix Paeoniae Rubra 60g, Pheretima 30g, Rhizoma Chuanxiong 30g, Semen Persicae 30g, Flos Carthami 30g decocts with water three times, for the first time add 8 times of amounts of water, decocted 1.5 hours, second and third time adds 8 times of amounts of water respectively, decocted respectively 1 hour, collecting decoction filters, it is 1.18～1.22,50 ℃ that filtrate decompression is concentrated into relative density, adds ethanol and makes that to contain alcohol amount be 75%, leaves standstill, get supernatant, reclaim ethanol, medicinal liquid concentrates, drying, be ground into fine powder, add Macrogol 4000 and Macrogol 600, make drop pill, promptly.
Embodiment four
Get above seven flavor medicine material, Radix Astragali 600g, Radix Angelicae Sinensis 60g, Radix Paeoniae Rubra 60g, Pheretima 30g, Rhizoma Chuanxiong 30g, Semen Persicae 30g, Flos Carthami 30g decocts with water three times, for the first time add 6 times of amounts of water, decocted 1.5 hours, second and third time adds 6 times of amounts of water respectively, decocted respectively 1 hour, collecting decoction filters, it is 1.18～1.22,50 ℃ that filtrate decompression is concentrated into relative density, adds ethanol and makes that to contain alcohol amount be 75%, leaves standstill, get supernatant, reclaim ethanol, medicinal liquid concentrates, drying, be ground into fine powder, add Polyethylene Glycol 8000 and PEG400, make drop pill, promptly.
The method for making of the drop pill of inrigorating qi and promoting blood circulation collateral dredging.Thrombus dispelling pill is used for wind-induced hemiplegia, facial hemiparalysis, and aphasia, slobbering, the lower limb fistula is useless, frequent micturition.Thrombus dispelling pill is with specific prepared, and it is little, easy to carry to have a dose, and the adjuvant sugar-free is convenient to the characteristics of diabetic to take.
Claims (5)
1, a kind of method for making of thrombus dispelling pill, prescription derives from " embolism extinguishing oral liquid ", and be characterized in: thrombus dispelling pill is in process of production, get the Radix Astragali, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Pheretima, Rhizoma Chuanxiong, Semen Persicae, flos carthami decocts with water three times, and 1.5 hours for the first time, second and third time was respectively 1 hour, collecting decoction, filter, it is 1.18～1.22,50 ℃ that filtrate decompression is concentrated into relative density, adds ethanol and makes that to contain the alcohol amount be 75%, leave standstill, get supernatant, reclaim ethanol, medicinal liquid concentrates, dry, be ground into fine powder, add Polyethylene Glycol, make drop pill.
2, the method for making of a kind of thrombus dispelling pill according to claim 1 is characterized in: thrombus dispelling pill is got the Radix Astragali in process of production, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Pheretima, Rhizoma Chuanxiong, Semen Persicae, flos carthami decoct with water three times, for the first time add 8 times of amounts of water, decocted second 1.5 hours, add 6 times of amounts of water for three times respectively, decocted respectively 1 hour, collecting decoction filters, it is 1.18～1.22 that filtrate decompression is concentrated into relative density, 50 ℃, add ethanol and make that to contain alcohol amount be 75%, leave standstill, get supernatant, reclaim ethanol, medicinal liquid concentrates, and drying is ground into fine powder, add polyethylene glycol 6000 and Macrogol 4000, make drop pill.
3, the method for making of a kind of thrombus dispelling pill according to claim 1 is characterized in: thrombus dispelling pill is got the Radix Astragali in process of production, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Pheretima, Rhizoma Chuanxiong, Semen Persicae, flos carthami decoct with water three times, for the first time add 10 times of amounts of water, decocted second 1.5 hours, add 8 times of amounts of water for three times respectively, decocted respectively 1 hour, collecting decoction filters, it is 1.18～1.22 that filtrate decompression is concentrated into relative density, 50 ℃, add ethanol and make that to contain alcohol amount be 75%, leave standstill, get supernatant, reclaim ethanol, medicinal liquid concentrates, drying, be ground into fine powder, add polyethylene glycol 6000, make drop pill, promptly.
4, the method for making of a kind of thrombus dispelling pill according to claim 1 is characterized in: thrombus dispelling pill is got the Radix Astragali in process of production, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Pheretima, Rhizoma Chuanxiong, Semen Persicae, flos carthami decoct with water three times, for the first time add 8 times of amounts of water, decocted second 1.5 hours, add 8 times of amounts of water for three times respectively, decocted respectively 1 hour, collecting decoction filters, and it is 1.18～1.22 that filtrate decompression is concentrated into relative density, 50 ℃, add ethanol and make that to contain alcohol amount be 75%, leave standstill, get supernatant, reclaim ethanol, medicinal liquid concentrates, dry, be ground into fine powder, add, ethylene glycol 4000 and Macrogol 600 are made drop pill.
5, the method for making of a kind of thrombus dispelling pill according to claim 1 is characterized in: thrombus dispelling pill is got the Radix Astragali in process of production, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Pheretima, Rhizoma Chuanxiong, Semen Persicae, flos carthami decoct with water three times, for the first time add 6 times of amounts of water, decocted second 1.5 hours, add 6 times of amounts of water for three times respectively, decocted respectively 1 hour, collecting decoction filters, and it is 1.18～1.22 that filtrate decompression is concentrated into relative density, 50 ℃, add ethanol and make that to contain alcohol amount be 75%, leave standstill, get supernatant, reclaim ethanol, medicinal liquid concentrates, dry, be ground into fine powder, add Polyethylene Glycol 8000 and PEG400, make drop pill.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510088076 CN1730037A (en) | 2005-08-03 | 2005-08-03 | Process for preparing thrombus eliminating dripping pills |
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| CN 200510088076 CN1730037A (en) | 2005-08-03 | 2005-08-03 | Process for preparing thrombus eliminating dripping pills |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101239095B (en) * | 2008-01-14 | 2011-04-13 | 三门峡赛诺维制药有限公司 | Method for preparing embolism-extinguishing enteric-coated capsule |
| CN103599214A (en) * | 2013-11-25 | 2014-02-26 | 三株福尔制药有限公司 | Probiotics fermented Xiaoshuan oral liquid and preparation method thereof |
-
2005
- 2005-08-03 CN CN 200510088076 patent/CN1730037A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101239095B (en) * | 2008-01-14 | 2011-04-13 | 三门峡赛诺维制药有限公司 | Method for preparing embolism-extinguishing enteric-coated capsule |
| CN103599214A (en) * | 2013-11-25 | 2014-02-26 | 三株福尔制药有限公司 | Probiotics fermented Xiaoshuan oral liquid and preparation method thereof |
| CN103599214B (en) * | 2013-11-25 | 2015-08-19 | 三株福尔制药有限公司 | A kind of probiotics fermentation-type embolism extinguishing oral liquid and preparation method thereof |
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