CN1689612A - Liver disease treating particle and its production method - Google Patents
Liver disease treating particle and its production method Download PDFInfo
- Publication number
- CN1689612A CN1689612A CNA2004100270596A CN200410027059A CN1689612A CN 1689612 A CN1689612 A CN 1689612A CN A2004100270596 A CNA2004100270596 A CN A2004100270596A CN 200410027059 A CN200410027059 A CN 200410027059A CN 1689612 A CN1689612 A CN 1689612A
- Authority
- CN
- China
- Prior art keywords
- radix
- curcumae
- salviae miltiorrhizae
- cortex phellodendri
- paeoniae rubra
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000004519 manufacturing process Methods 0.000 title claims description 19
- 208000019423 liver disease Diseases 0.000 title abstract description 5
- 239000002245 particle Substances 0.000 title description 2
- 239000008187 granular material Substances 0.000 claims abstract description 18
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 7
- 239000000284 extract Substances 0.000 claims abstract description 6
- 239000000341 volatile oil Substances 0.000 claims abstract description 6
- 239000004375 Dextrin Substances 0.000 claims abstract description 5
- 229920001353 Dextrin Polymers 0.000 claims abstract description 5
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims abstract description 5
- 229930006000 Sucrose Natural products 0.000 claims abstract description 5
- 235000019425 dextrin Nutrition 0.000 claims abstract description 5
- 238000002156 mixing Methods 0.000 claims abstract description 5
- 238000001035 drying Methods 0.000 claims abstract description 4
- 210000004185 liver Anatomy 0.000 claims description 26
- 238000000034 method Methods 0.000 claims description 15
- 238000004821 distillation Methods 0.000 claims description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 7
- 239000007864 aqueous solution Substances 0.000 claims description 6
- 239000012141 concentrate Substances 0.000 claims description 5
- 239000000706 filtrate Substances 0.000 claims description 4
- 239000000843 powder Substances 0.000 claims description 4
- 239000005720 sucrose Substances 0.000 claims description 3
- 244000163122 Curcuma domestica Species 0.000 claims description 2
- 235000003392 Curcuma domestica Nutrition 0.000 claims description 2
- 235000003373 curcuma longa Nutrition 0.000 claims description 2
- 235000013976 turmeric Nutrition 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 6
- 238000002360 preparation method Methods 0.000 abstract description 4
- 231100000331 toxic Toxicity 0.000 abstract description 2
- 230000002588 toxic effect Effects 0.000 abstract description 2
- 235000014375 Curcuma Nutrition 0.000 abstract 3
- 244000164480 Curcuma aromatica Species 0.000 abstract 3
- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 abstract 3
- 239000000463 material Substances 0.000 abstract 2
- 229960004793 sucrose Drugs 0.000 abstract 2
- 235000008658 Artemisia capillaris Nutrition 0.000 abstract 1
- 241000092668 Artemisia capillaris Species 0.000 abstract 1
- NEZONWMXZKDMKF-UHFFFAOYSA-N C.I. Natural Red 20 Chemical compound C1=CC(O)=C2C(=O)C(C(O)CC=C(C)C)=CC(=O)C2=C1O NEZONWMXZKDMKF-UHFFFAOYSA-N 0.000 abstract 1
- 240000004035 Lithospermum officinale Species 0.000 abstract 1
- 235000011030 Lithospermum officinale Nutrition 0.000 abstract 1
- 244000153955 Reynoutria sachalinensis Species 0.000 abstract 1
- 235000003202 Reynoutria sachalinensis Nutrition 0.000 abstract 1
- 244000299790 Rheum rhabarbarum Species 0.000 abstract 1
- 235000009411 Rheum rhabarbarum Nutrition 0.000 abstract 1
- 235000019441 ethanol Nutrition 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 239000003921 oil Substances 0.000 abstract 1
- 238000012856 packing Methods 0.000 abstract 1
- 238000005453 pelletization Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 9
- 208000002672 hepatitis B Diseases 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 4
- 208000006454 hepatitis Diseases 0.000 description 2
- 231100000283 hepatitis Toxicity 0.000 description 2
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 238000003754 machining Methods 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The hepatosis treating granule consists of extract of curcuma root, capillary artemisia, giant knotweed, gromwell, rhubarb and other four kinds of Chinese medicinal materials, cane sugar, dextrin, etc. The preparation process includes the steps of extracting volatile curcuma root oil, twice decocting the curcuma root residue with other eight kinds of Chinese medicinal materials, filtering, concentrating, mixing with cane sugar, dextrin and alcohol, pelletizing, drying, mixing with the volatile oil and packing. The hepatosis treating granule has easy taking, obvious curative effect, high curative rate, no toxic side effect, simple preparation process and low cost.
Description
Technical field
The present invention relates to a kind of smart liver granule, especially a kind of batchings such as Chinese medicine of utilizing are made, and are used for the treatment of the medicine of liver diseases such as hepatitis B, and the manufacture method of this medicine.
Background technology
At present, hepatitis B patient is a lot of, though the medicine that state's internal therapy should disease is a lot, but the definite person of inefficacy still at present, as Chinese patent application number be 92102829.6 anti-hepatitis B surface antigen granules and manufacture method thereof, and Chinese patent application number is the production method of 90108576.6 hepatitis spirit, all disclosed some hepatitis medicaments and production method.But in clinical practice, pharmacological action is not strong mostly, and curative effect is not remarkable, and the part medicine has stronger zest to stomach, and cure rate is low, also has some medicine manufacturing process complicated, and cost is higher.
Summary of the invention
The purpose of this invention is to provide a kind of smart liver granule, not only be easy to take, evident in efficacy, the cure rate height has no side effect, and technology is simple, and cost is lower; Another object of the present invention provides the particulate manufacture method of above-mentioned smart liver.
Technical program of the present invention lies in this essence liver granule, its prescription mainly can be made up of Herba Artemisiae Scopariae, Rhizoma Polygoni Cuspidati, Radix Arnebiae (Radix Lithospermi), Radix Et Rhizoma Rhei, Cortex Phellodendri, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Radix Curcumae, Radix Glycyrrhizae.Through specific processing technique, make drug particles, thereby reach significant curative effect hepatitis B patient, avoid toxic and side effects, and simplify technology, reduce cost.
Smart liver granule provided by the present invention mainly combines Chinese medicine preparations such as Herba Artemisiae Scopariae, Rhizoma Polygoni Cuspidati, Radix Arnebiae (Radix Lithospermi), Radix Et Rhizoma Rhei, Cortex Phellodendri, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Radix Curcumae, Radix Glycyrrhizae and some batchings, contains suitable amount of sucrose and dextrin simultaneously, and adequate amount of ethanol.
Smart liver granule among the present invention, the weight proportion that feeds intake of main component is in its prescription: Herba Artemisiae Scopariae 10～20, Rhizoma Polygoni Cuspidati 10～20, Radix Arnebiae (Radix Lithospermi) 5～15, Radix Et Rhizoma Rhei 5～15, Cortex Phellodendri 5～15, Radix Paeoniae Rubra 5～15, Radix Salviae Miltiorrhizae 5～15, Radix Curcumae 5～15, Radix Glycyrrhizae 2～11.
Smart liver granule among the present invention, the optimization of the main component weight proportion that feeds intake is in its prescription: Herba Artemisiae Scopariae 12～18, Rhizoma Polygoni Cuspidati 12～18, Radix Arnebiae (Radix Lithospermi) 7～13, Radix Et Rhizoma Rhei 7～13, Cortex Phellodendri 7～13, Radix Paeoniae Rubra 7～13, Radix Salviae Miltiorrhizae 7～13, Radix Curcumae 7～13, Radix Glycyrrhizae 3～9.
Smart liver granule among the present invention, the optimum of the main component weight proportion that feeds intake is in its prescription: Herba Artemisiae Scopariae 15, Rhizoma Polygoni Cuspidati 15, Radix Arnebiae (Radix Lithospermi) 10, Radix Et Rhizoma Rhei 10, Cortex Phellodendri 10, Radix Paeoniae Rubra 10, Radix Salviae Miltiorrhizae 10, Radix Curcumae 10, Radix Glycyrrhizae 6.
The particulate manufacture method of smart liver provided by the present invention comprises the following key step that comprises:
Turmeric powder is broken into coarse powder, extracts volatile oil, the aqueous solution after distilling is collected in distillation;
Medicinal residues and Herba Artemisiae Scopariae, Rhizoma Polygoni Cuspidati, Radix Arnebiae (Radix Lithospermi), Radix Et Rhizoma Rhei, Cortex Phellodendri, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Radix Curcumae, Radix Glycyrrhizae after the Radix Curcumae distillation are all decocted with water;
Collecting decoction filters, and the aqueous solution that collect filtrate and Radix Curcumae distillation back merges, and concentrates;
Concentrate is granulated, and drying adds the volatile oil that extracts from Radix Curcumae, mixing.
In the above-mentioned particulate manufacture method of smart liver, it is 1 to 4 time that the medicinal residues after the described Radix Curcumae distillation and Herba Artemisiae Scopariae, Rhizoma Polygoni Cuspidati, Radix Arnebiae (Radix Lithospermi), Radix Et Rhizoma Rhei, Cortex Phellodendri, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Radix Curcumae, Radix Glycyrrhizae decoct with water number of times.As optimum selection, decocting number of times is 2 times.
In the above-mentioned particulate manufacture method of smart liver, the time that the medicinal residues after the described Radix Curcumae distillation and Herba Artemisiae Scopariae, Rhizoma Polygoni Cuspidati, Radix Arnebiae (Radix Lithospermi), Radix Et Rhizoma Rhei, Cortex Phellodendri, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Radix Curcumae, Radix Glycyrrhizae decoct with water was advisable with 0.5 to 5 hour, and optimum selection is about 1.5 hours.
Among the above-mentioned particulate step of manufacturing C of smart liver, after the aqueous solution after the distillation of filtrate and Radix Curcumae merges, concentrating processing again, is 1.35～1.38 clear paste until being concentrated into relative density.
After making clear paste, also should add suitable amount of sucrose, dextrin, and add adequate amount of ethanol, granulation, drying add the volatile oil that extracts, mixing from Radix Curcumae then.After machining, pack again.
Smart liver granule of the present invention and manufacture method thereof are compared with existing preparation, to liver diseases such as hepatitis B have evident in efficacy, cure rate is high and nontoxic, side effect and to advantages such as gastrointestinal tract are non-stimulated, technology is simple, cost is lower.
The smart liver granule of the present invention is easy to take, and through clinical trial, proves that effective percentage reaches more than 94%.
Claims (10)
1, a kind of smart liver granule is characterized in that: this essence liver granule mainly contains Herba Artemisiae Scopariae, Rhizoma Polygoni Cuspidati, Radix Arnebiae (Radix Lithospermi), Radix Et Rhizoma Rhei, Cortex Phellodendri, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Radix Curcumae, Radix Glycyrrhizae.
2, smart liver granule as claimed in claim 1 is characterized in that: the weight portion proportioning that feeds intake of described main component is: Herba Artemisiae Scopariae 10～20, Rhizoma Polygoni Cuspidati 10～20, Radix Arnebiae (Radix Lithospermi) 5～15, Radix Et Rhizoma Rhei 5～15, Cortex Phellodendri 5～15, Radix Paeoniae Rubra 5～15, Radix Salviae Miltiorrhizae 5～15, Radix Curcumae 5～15, Radix Glycyrrhizae 2～11.
3, smart liver granule as claimed in claim 1 is characterized in that: the weight portion that feeds intake of described main component is optimized proportioning and is: Herba Artemisiae Scopariae 12～18, Rhizoma Polygoni Cuspidati 12～18, Radix Arnebiae (Radix Lithospermi) 7～13, Radix Et Rhizoma Rhei 7～13, Cortex Phellodendri 7～13, Radix Paeoniae Rubra 7～13, Radix Salviae Miltiorrhizae 7～13, Radix Curcumae 7～13, Radix Glycyrrhizae 3～9.
4, smart liver granule as claimed in claim 1 is characterized in that: the weight portion optimal proportion that feeds intake of described main component is: Herba Artemisiae Scopariae 15, Rhizoma Polygoni Cuspidati 15, Radix Arnebiae (Radix Lithospermi) 10, Radix Et Rhizoma Rhei 10, Cortex Phellodendri 10, Radix Paeoniae Rubra 10, Radix Salviae Miltiorrhizae 10, Radix Curcumae 10, Radix Glycyrrhizae 6.
5, the particulate manufacture method of a kind of smart liver: it is characterized in that may further comprise the steps:
Turmeric powder is broken into coarse powder, extracts volatile oil, distillation, collect the aqueous solution after distilling:
Medicinal residues and Herba Artemisiae Scopariae, Rhizoma Polygoni Cuspidati, Radix Arnebiae (Radix Lithospermi), Radix Et Rhizoma Rhei, Cortex Phellodendri, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Radix Curcumae, Radix Glycyrrhizae after the Radix Curcumae distillation are all decocted with water;
Collecting decoction filters, and the aqueous solution that collect filtrate and Radix Curcumae distillation back merges, and concentrates;
Concentrate is granulated, and drying adds the volatile oil that extracts from Radix Curcumae, mixing.
6, the particulate manufacture method of smart liver as claimed in claim 5 is characterized in that: it is 1 to 4 time that the medicinal residues after the described Radix Curcumae distillation and Herba Artemisiae Scopariae, Rhizoma Polygoni Cuspidati, Radix Arnebiae (Radix Lithospermi), Radix Et Rhizoma Rhei, Cortex Phellodendri, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Radix Curcumae, Radix Glycyrrhizae decoct with water number of times.
7, the particulate manufacture method of smart liver as claimed in claim 5 is characterized in that: the best number of times that the medicinal residues after the described Radix Curcumae distillation and Herba Artemisiae Scopariae, Rhizoma Polygoni Cuspidati, Radix Arnebiae (Radix Lithospermi), Radix Et Rhizoma Rhei, Cortex Phellodendri, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Radix Curcumae, Radix Glycyrrhizae decoct with water is 2 times.
8, the particulate manufacture method of smart liver as claimed in claim 5 is characterized in that: it is 0.5 to 5 hour that the medicinal residues after the described Radix Curcumae distillation and Herba Artemisiae Scopariae, Rhizoma Polygoni Cuspidati, Radix Arnebiae (Radix Lithospermi), Radix Et Rhizoma Rhei, Cortex Phellodendri, Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae, Radix Curcumae, Radix Glycyrrhizae decoct with water the time.
9, the particulate manufacture method of smart liver as claimed in claim 5 is characterized in that: after the aqueous solution after filtrate and the Radix Curcumae distillation among the step C is merged, be concentrated into relative density and be 1.35～1.38 clear paste.
10, the particulate manufacture method of smart liver as claimed in claim 5 is characterized in that: adding sucrose, dextrin and ethanol were an amount of when concentrate was granulated.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410027059 CN1689612B (en) | 2004-04-29 | 2004-04-29 | Liver disease treating particle and its production method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410027059 CN1689612B (en) | 2004-04-29 | 2004-04-29 | Liver disease treating particle and its production method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1689612A true CN1689612A (en) | 2005-11-02 |
| CN1689612B CN1689612B (en) | 2012-09-05 |
Family
ID=35345566
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200410027059 Expired - Lifetime CN1689612B (en) | 2004-04-29 | 2004-04-29 | Liver disease treating particle and its production method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1689612B (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105148195A (en) * | 2015-09-26 | 2015-12-16 | 张文俊 | Chinese patent medicine for treating hepatitis B |
| CN110780018A (en) * | 2019-11-29 | 2020-02-11 | 广东红珊瑚药业有限公司 | Quality control method of Jinggan granules |
| CN110882370A (en) * | 2019-12-20 | 2020-03-17 | 何文法 | Chinese medicinal composition for preventing or treating hepatitis B |
| CN111643636A (en) * | 2020-07-06 | 2020-09-11 | 河南中医药大学第一附属医院 | Traditional Chinese medicine granules for treating liver disease enterogenic endotoxemia and preparation method thereof |
| CN112057599A (en) * | 2020-10-26 | 2020-12-11 | 北京沃德中医药研究院 | Chinese medicine for treating viral hepatitis B and its preparing process |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1151317A (en) * | 1996-09-16 | 1997-06-11 | 单晓春 | Instant powder for treatment of liver disease and its prodn. tech. |
| CN1425417A (en) * | 2002-12-27 | 2003-06-25 | 支金华 | Medicine for dispelling heat of liver and toxin to treat hepatitis B |
-
2004
- 2004-04-29 CN CN 200410027059 patent/CN1689612B/en not_active Expired - Lifetime
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1151317A (en) * | 1996-09-16 | 1997-06-11 | 单晓春 | Instant powder for treatment of liver disease and its prodn. tech. |
| CN1425417A (en) * | 2002-12-27 | 2003-06-25 | 支金华 | Medicine for dispelling heat of liver and toxin to treat hepatitis B |
Non-Patent Citations (1)
| Title |
|---|
| 谭天: "茵陈赤芍汤治疗甲乙型肝炎重叠感染108例", 《浙江中医杂志》 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105148195A (en) * | 2015-09-26 | 2015-12-16 | 张文俊 | Chinese patent medicine for treating hepatitis B |
| CN110780018A (en) * | 2019-11-29 | 2020-02-11 | 广东红珊瑚药业有限公司 | Quality control method of Jinggan granules |
| CN110882370A (en) * | 2019-12-20 | 2020-03-17 | 何文法 | Chinese medicinal composition for preventing or treating hepatitis B |
| CN111643636A (en) * | 2020-07-06 | 2020-09-11 | 河南中医药大学第一附属医院 | Traditional Chinese medicine granules for treating liver disease enterogenic endotoxemia and preparation method thereof |
| CN112057599A (en) * | 2020-10-26 | 2020-12-11 | 北京沃德中医药研究院 | Chinese medicine for treating viral hepatitis B and its preparing process |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1689612B (en) | 2012-09-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1044974C (en) | Anti- hepatitis B preparation | |
| CN101987123B (en) | Medicament for easing pain of human body and preparation method thereof | |
| CN101987122B (en) | Medicament for easing pain of human body and preparation method thereof | |
| CN101099763A (en) | Traditional Chinese medicine for treating headache | |
| CN103027992A (en) | Preparation method of drug for nourishing blood, relaxing muscles and treating rheumatism | |
| CN102397372A (en) | Medicinal composition and pharmaceutical preparation and application thereof to treating irritable bowel syndrome | |
| CN106377646A (en) | Six-ingredient rehmannia root granule and preparation method thereof | |
| CN1689612B (en) | Liver disease treating particle and its production method | |
| CN1785391A (en) | Chinese medicinal composition and its preparation method | |
| CN1251729C (en) | Chinese herbal medicinal compositon for treating prostate disease | |
| CN102688336A (en) | Bezoar supernatant composite and preparation method thereof | |
| CN102198230A (en) | Medicinal preparation for treating infantile repeated cold and preparation method thereof | |
| CN101085130A (en) | Medicinal composition for treating acute renal failure | |
| CN100360156C (en) | Chinese medicine composition new use | |
| CN1210054C (en) | Novel preparation method for ageratum zhengqi capsule | |
| CN1175873C (en) | Preparation technology of | |
| CN101028319B (en) | Chinese-medicine compound preparation against coronary heart disease and its production | |
| CN101385783A (en) | Huganning tablets for treating chronic and urgent liver disease and preparation method thereof | |
| CN1319578C (en) | Prescription of Chinese medicine compound preparation, its preparation method and use | |
| CN1314434C (en) | Heat-clearing and detoxic medicine and its preparation method | |
| CN1686451A (en) | Heart nourishing palpitation stabilizing granules and its preparation method | |
| CN1238028C (en) | Method for preparing capsule of six drugs containing rehmannine | |
| CN109364213A (en) | A kind of herbal mixture for treating liver fibrosis | |
| CN1194733C (en) | Medicine for treating hyperthyroidism and its prepn | |
| CN1060663C (en) | Compound Tibet capillary artemisia patent medicine |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C56 | Change in the name or address of the patentee | ||
| CP02 | Change in the address of a patent holder |
Address after: 523808 Guangdong province Dongguan City Songshan Lake high tech Industrial Development Zone, Chang Park Road No. 2 Patentee after: GUANGDONG HONGSHANHU PHARMACEUTICAL CO.,LTD. Address before: 524022, No. 5, Long Ping Nan Road, Zhanjiang economic and Technological Development Zone, Zhanjiang, Guangdong Patentee before: GUANGDONG HONGSHANHU PHARMACEUTICAL CO.,LTD. |
|
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20120905 |