CN1665840A - 含有免疫球蛋白结构域的细胞表面识别分子 - Google Patents

含有免疫球蛋白结构域的细胞表面识别分子 Download PDF

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Publication number
CN1665840A
CN1665840A CN038152525A CN03815252A CN1665840A CN 1665840 A CN1665840 A CN 1665840A CN 038152525 A CN038152525 A CN 038152525A CN 03815252 A CN03815252 A CN 03815252A CN 1665840 A CN1665840 A CN 1665840A
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Prior art keywords
polypeptide
seq
nucleic acid
acid molecule
disease
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Pending
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CN038152525A
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English (en)
Chinese (zh)
Inventor
A·R·戴维斯
R·J·法根
C·B·菲尔普斯
C·鲍尔
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Ares Trading SA
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Ares Trading SA
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Publication of CN1665840A publication Critical patent/CN1665840A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Plant Pathology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
CN038152525A 2002-04-30 2003-04-30 含有免疫球蛋白结构域的细胞表面识别分子 Pending CN1665840A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0209884.6A GB0209884D0 (en) 2002-04-30 2002-04-30 Proteins
GB0209884.6 2002-04-30

Publications (1)

Publication Number Publication Date
CN1665840A true CN1665840A (zh) 2005-09-07

Family

ID=9935806

Family Applications (1)

Application Number Title Priority Date Filing Date
CN038152525A Pending CN1665840A (zh) 2002-04-30 2003-04-30 含有免疫球蛋白结构域的细胞表面识别分子

Country Status (16)

Country Link
US (1) US7622555B2 (cg-RX-API-DMAC7.html)
EP (1) EP1499640A2 (cg-RX-API-DMAC7.html)
JP (1) JP2006502702A (cg-RX-API-DMAC7.html)
KR (1) KR20050008699A (cg-RX-API-DMAC7.html)
CN (1) CN1665840A (cg-RX-API-DMAC7.html)
AU (1) AU2003229961B2 (cg-RX-API-DMAC7.html)
BR (1) BR0309638A (cg-RX-API-DMAC7.html)
CA (1) CA2483038A1 (cg-RX-API-DMAC7.html)
EA (1) EA007985B1 (cg-RX-API-DMAC7.html)
GB (1) GB0209884D0 (cg-RX-API-DMAC7.html)
IL (1) IL164777A0 (cg-RX-API-DMAC7.html)
MX (1) MXPA04010674A (cg-RX-API-DMAC7.html)
NO (1) NO20044628L (cg-RX-API-DMAC7.html)
RS (1) RS92704A (cg-RX-API-DMAC7.html)
WO (1) WO2003093316A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200408453B (cg-RX-API-DMAC7.html)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100402551C (zh) * 2006-04-14 2008-07-16 中国科学院长春应用化学研究所 β2-微球蛋白的抗原表位及应用
CN107526942A (zh) * 2017-07-18 2017-12-29 中山大学 生命组学序列数据的反向检索方法

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0326393D0 (en) * 2003-11-12 2003-12-17 Ares Trading Sa Cytokine antagonist molecules
US20080193414A1 (en) * 2005-05-06 2008-08-14 Amanda Proudfoot Use of an Immunoglobulin Domain-Containing Cell Surface Recognition Molecule For Treating Diseases
JP2010500978A (ja) 2006-08-17 2010-01-14 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ウイルスポリメラーゼインヒビター
US8178101B2 (en) 2007-05-21 2012-05-15 Alderbio Holdings Inc. Use of anti-IL-6 antibodies having specific binding properties to treat cachexia
KR101829776B1 (ko) 2007-05-21 2018-02-19 앨더바이오 홀딩스 엘엘씨 Ｉｌ-６에 대한 항체 및 이의 용도
US8252286B2 (en) 2007-05-21 2012-08-28 Alderbio Holdings Llc Antagonists of IL-6 to prevent or treat thrombosis
US7906117B2 (en) 2007-05-21 2011-03-15 Alderbio Holdings Llc Antagonists of IL-6 to prevent or treat cachexia, weakness, fatigue, and/or fever
US8062864B2 (en) * 2007-05-21 2011-11-22 Alderbio Holdings Llc Nucleic acids encoding antibodies to IL-6, and recombinant production of anti-IL-6 antibodies
US8404235B2 (en) 2007-05-21 2013-03-26 Alderbio Holdings Llc Antagonists of IL-6 to raise albumin and/or lower CRP
US9701747B2 (en) 2007-05-21 2017-07-11 Alderbio Holdings Llc Method of improving patient survivability and quality of life by anti-IL-6 antibody administration
US8992920B2 (en) 2008-11-25 2015-03-31 Alderbio Holdings Llc Anti-IL-6 antibodies for the treatment of arthritis
US9452227B2 (en) 2008-11-25 2016-09-27 Alderbio Holdings Llc Methods of treating or diagnosing conditions associated with elevated IL-6 using anti-IL-6 antibodies or fragments
US9212223B2 (en) 2008-11-25 2015-12-15 Alderbio Holdings Llc Antagonists of IL-6 to prevent or treat thrombosis
US8323649B2 (en) 2008-11-25 2012-12-04 Alderbio Holdings Llc Antibodies to IL-6 and use thereof
US8420089B2 (en) 2008-11-25 2013-04-16 Alderbio Holdings Llc Antagonists of IL-6 to raise albumin and/or lower CRP
US8337847B2 (en) 2008-11-25 2012-12-25 Alderbio Holdings Llc Methods of treating anemia using anti-IL-6 antibodies
EP2504030A4 (en) 2009-11-24 2013-06-26 Alderbio Holdings Llc IL-6 ANTAGONISTS FOR INCREASING ALBUMIN AND / OR REDUCING CRP
US9775921B2 (en) 2009-11-24 2017-10-03 Alderbio Holdings Llc Subcutaneously administrable composition containing anti-IL-6 antibody
AU2011332817A1 (en) 2010-11-23 2013-06-13 Alder Biopharmaceuticals, Inc. Anti-IL-6 antibodies for the treatment of anemia
WO2017184831A1 (en) 2016-04-20 2017-10-26 Regeneron Pharmaceuticals, Inc. Compositions and methods for making antibodies based on use of an expression-enhancing locus

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6420526B1 (en) * 1997-03-07 2002-07-16 Human Genome Sciences, Inc. 186 human secreted proteins
GB2331666A (en) * 1997-11-20 1999-05-26 Dsc Telecom Lp Subscriber Terminal for a Wireless Telecommunications System
US6783961B1 (en) * 1999-02-26 2004-08-31 Genset S.A. Expressed sequence tags and encoded human proteins
CA2296792A1 (en) 1999-02-26 2000-08-26 Genset S.A. Expressed sequence tags and encoded human proteins
EP1285084A1 (en) * 2000-01-25 2003-02-26 Hyseq, Inc. Novel nucleic acids and polypeptides
JP2004530409A (ja) * 2000-10-27 2004-10-07 インサイト・ゲノミックス・インコーポレイテッド 膜貫通タンパク質
JP2004535759A (ja) * 2000-11-16 2004-12-02 インサイト・ゲノミックス・インコーポレイテッド 免疫グロブリンスーパファミリタンパク質
AU2003261142A1 (en) 2002-07-12 2004-02-02 Nuvelo,Inc. Methods and materials relating to novel polypeptides and polynucleotides
CA2500521A1 (en) 2002-10-02 2004-09-23 Nuvelo, Inc. Novel nucleic acids and polypeptides

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100402551C (zh) * 2006-04-14 2008-07-16 中国科学院长春应用化学研究所 β2-微球蛋白的抗原表位及应用
CN107526942A (zh) * 2017-07-18 2017-12-29 中山大学 生命组学序列数据的反向检索方法
CN107526942B (zh) * 2017-07-18 2021-04-20 中山大学 生命组学序列数据的反向检索方法

Also Published As

Publication number Publication date
KR20050008699A (ko) 2005-01-21
NO20044628L (no) 2004-12-29
EA007985B1 (ru) 2007-02-27
GB0209884D0 (en) 2002-06-05
BR0309638A (pt) 2005-03-01
US7622555B2 (en) 2009-11-24
IL164777A0 (en) 2005-12-18
EA200401453A1 (ru) 2005-06-30
ZA200408453B (en) 2006-07-26
JP2006502702A (ja) 2006-01-26
RS92704A (sr) 2006-12-15
AU2003229961B2 (en) 2009-02-19
AU2003229961A1 (en) 2003-11-17
EP1499640A2 (en) 2005-01-26
CA2483038A1 (en) 2003-11-13
WO2003093316A3 (en) 2004-02-12
US20040204352A1 (en) 2004-10-14
MXPA04010674A (es) 2005-02-17
WO2003093316A2 (en) 2003-11-13

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