CN1656236A - 用于病原体和生物物质检测与特性分析的设备及方法 - Google Patents
用于病原体和生物物质检测与特性分析的设备及方法 Download PDFInfo
- Publication number
- CN1656236A CN1656236A CNA038118688A CN03811868A CN1656236A CN 1656236 A CN1656236 A CN 1656236A CN A038118688 A CNA038118688 A CN A038118688A CN 03811868 A CN03811868 A CN 03811868A CN 1656236 A CN1656236 A CN 1656236A
- Authority
- CN
- China
- Prior art keywords
- antibody
- virus
- deposited
- target
- deposited material
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
- G01N33/553—Metal or metal coated
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y35/00—Methods or apparatus for measurement or analysis of nanostructures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/01—DNA viruses
- G01N2333/065—Poxviridae, e.g. avipoxvirus
- G01N2333/07—Vaccinia virus; Variola virus
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/84—Manufacture, treatment, or detection of nanostructure
- Y10S977/849—Manufacture, treatment, or detection of nanostructure with scanning probe
- Y10S977/852—Manufacture, treatment, or detection of nanostructure with scanning probe for detection of specific nanostructure sample or nanostructure-related property
- Y10S977/853—Biological sample
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Virology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/160,372 | 2002-05-30 | ||
| US10/160,372 US6897015B2 (en) | 2000-03-07 | 2002-05-30 | Device and method of use for detection and characterization of pathogens and biological materials |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1656236A true CN1656236A (zh) | 2005-08-17 |
Family
ID=29709705
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA038118688A Pending CN1656236A (zh) | 2002-05-30 | 2003-05-29 | 用于病原体和生物物质检测与特性分析的设备及方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6897015B2 (enExample) |
| EP (1) | EP1513954A4 (enExample) |
| JP (1) | JP2005527830A (enExample) |
| KR (1) | KR20050026395A (enExample) |
| CN (1) | CN1656236A (enExample) |
| AU (1) | AU2003238783A1 (enExample) |
| CA (1) | CA2487792A1 (enExample) |
| WO (1) | WO2003101278A2 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070166741A1 (en) * | 1998-12-14 | 2007-07-19 | Somalogic, Incorporated | Multiplexed analyses of test samples |
| US20030073250A1 (en) * | 1999-05-21 | 2003-04-17 | Eric Henderson | Method and apparatus for solid state molecular analysis |
| US6573369B2 (en) * | 1999-05-21 | 2003-06-03 | Bioforce Nanosciences, Inc. | Method and apparatus for solid state molecular analysis |
| US20020042081A1 (en) * | 2000-10-10 | 2002-04-11 | Eric Henderson | Evaluating binding affinities by force stratification and force panning |
| US6897015B2 (en) | 2000-03-07 | 2005-05-24 | Bioforce Nanosciences, Inc. | Device and method of use for detection and characterization of pathogens and biological materials |
| EP1348113B1 (en) | 2000-08-15 | 2008-07-30 | Bioforce Nanosciences, Inc. | Nanoscale molecular arrayer |
| EP1565747B1 (en) * | 2001-03-29 | 2013-11-27 | Cellect Technologies Corp. | Method and system for separating and sorting particles |
| WO2003008941A2 (en) * | 2001-07-17 | 2003-01-30 | Bioforce Nanosciences, Inc. | Combined molecular blinding detection through force microscopy and mass spectrometry |
| US7042488B2 (en) | 2001-09-27 | 2006-05-09 | Fujinon Corporation | Electronic endoscope for highlighting blood vessel |
| JP2005534041A (ja) * | 2002-07-24 | 2005-11-10 | ヨットペーカー、インストルメンツ、アクチエンゲゼルシャフト | 走査プローブ技術を用いた局部的に高分解能な表層の質量分光学的特性調査のための方法 |
| CN1745179A (zh) * | 2003-01-02 | 2006-03-08 | 拜澳富斯毫微科学有限公司 | 在小样品体积中分子分析的方法和装置 |
| DE10346286B3 (de) | 2003-10-06 | 2005-04-14 | J. Eberspächer GmbH & Co. KG | Abgasreinigungsanordnung |
| FR2860872A1 (fr) * | 2003-10-09 | 2005-04-15 | Commissariat Energie Atomique | Micro-capteurs et nano-capteurs d'especes chimiques et biologiques a plasmons de surface |
| JP2005233705A (ja) * | 2004-02-18 | 2005-09-02 | Kitakyushu Foundation For The Advancement Of Industry Science & Technology | 生体物質固定化チップ及び生体物質の固定化方法 |
| ATE390562T1 (de) * | 2004-11-19 | 2008-04-15 | Ebm Papst St Georgen Gmbh & Co | Anordnung mit einem luefter und einer pumpe |
| US20060246599A1 (en) * | 2005-04-29 | 2006-11-02 | Sarah Rosenstein | Lateral flow device |
| US7300631B2 (en) * | 2005-05-02 | 2007-11-27 | Bioscale, Inc. | Method and apparatus for detection of analyte using a flexural plate wave device and magnetic particles |
| WO2006138161A2 (en) * | 2005-06-16 | 2006-12-28 | The Regents Of The University Of California | Large scale parallel immuno-based allergy test and device for evanescent field excitation of fluorescence |
| CN100424174C (zh) * | 2005-09-01 | 2008-10-08 | 上海交通大学 | 原子力显微镜诱导单分子dna定位突变方法 |
| AU2006287336A1 (en) * | 2005-09-09 | 2007-03-15 | The University Of Chicago | Methods and compositions for diagnosis and immunotherapy of pollen allergy |
| EP1801594A1 (en) * | 2005-12-23 | 2007-06-27 | Koninklijke Philips Electronics N.V. | Sensing device and method for determination of the amount of target molecule in an analyte |
| EP2613147B1 (en) * | 2006-01-17 | 2015-03-11 | Somalogic, Inc. | Detection methods using aptamers |
| KR100740891B1 (ko) * | 2006-02-27 | 2007-07-19 | 한국과학기술원 | 금나노-펩타이드칩 및 이의 이차이온 질량분석법을 이용한효소 활성 및 효소 활성 저해효과 분석 방법 |
| US7569789B2 (en) * | 2006-03-16 | 2009-08-04 | Visiongate, Inc. | Cantilevered coaxial flow injector apparatus and method for sorting particles |
| US20080011058A1 (en) * | 2006-03-20 | 2008-01-17 | The Regents Of The University Of California | Piezoresistive cantilever based nanoflow and viscosity sensor for microchannels |
| WO2007132373A1 (en) * | 2006-05-09 | 2007-11-22 | Koninklijke Philips Electronics N. V. | Detection of target molecules in a sample by using a magnetic field |
| US7964356B2 (en) * | 2007-01-16 | 2011-06-21 | Somalogic, Inc. | Method for generating aptamers with improved off-rates |
| US8975026B2 (en) | 2007-01-16 | 2015-03-10 | Somalogic, Inc. | Method for generating aptamers with improved off-rates |
| US7855054B2 (en) * | 2007-01-16 | 2010-12-21 | Somalogic, Inc. | Multiplexed analyses of test samples |
| US8191403B2 (en) * | 2007-03-27 | 2012-06-05 | Richmond Chemical Corporation | Petroleum viscosity measurement and communication system and method |
| KR100869909B1 (ko) | 2007-06-10 | 2008-11-21 | 한국과학기술원 | 금 나노입자 단층막 기반의 바이오칩을 이용한 단백질과 생체분자간의 반응 검출방법 |
| US8941057B2 (en) * | 2007-09-05 | 2015-01-27 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Probe and method for obtaining three-dimensional compositional maps of a biological sample |
| US8906700B2 (en) | 2007-11-06 | 2014-12-09 | Ambergen, Inc. | Methods and compositions for phototransfer |
| US8703416B2 (en) | 2008-07-17 | 2014-04-22 | Somalogic, Inc. | Method for purification and identification of sperm cells |
| WO2011106057A2 (en) * | 2009-12-04 | 2011-09-01 | Trustees Of Boston University | Nanostructure biosensors and systems and methods of use thereof |
| CN102073872B (zh) * | 2011-01-20 | 2012-10-10 | 中国疾病预防控制中心寄生虫病预防控制所 | 基于图像的寄生虫虫卵形状识别方法 |
| US9147505B2 (en) | 2011-11-02 | 2015-09-29 | Ut-Battelle, Llc | Large area controlled assembly of transparent conductive networks |
| US20190285624A1 (en) * | 2016-07-19 | 2019-09-19 | Bio-Techne Corporation | Surface plasmon resonance sensor chip having sensor surface capable of capturing multiple species of antibodies and method of making |
Family Cites Families (113)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4728591A (en) * | 1986-03-07 | 1988-03-01 | Trustees Of Boston University | Self-assembled nanometer lithographic masks and templates and method for parallel fabrication of nanometer scale multi-device structures |
| US5720928A (en) * | 1988-09-15 | 1998-02-24 | New York University | Image processing and analysis of individual nucleic acid molecules |
| US5514550A (en) * | 1989-02-03 | 1996-05-07 | Johnson & Johnson Clinical Diagnostics, Inc. | Nucleic acid test article and its use to detect a predetermined nucleic acid |
| US5800992A (en) * | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
| US6416952B1 (en) * | 1989-06-07 | 2002-07-09 | Affymetrix, Inc. | Photolithographic and other means for manufacturing arrays |
| US5744101A (en) * | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
| US5143854A (en) * | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| ES2045932T3 (es) * | 1989-06-12 | 1994-01-16 | Cis Bio Int | Procedimiento para la deteccion de secuencias especificas de acidos nucleicos y sus aplicaciones. |
| US5106729A (en) * | 1989-07-24 | 1992-04-21 | Arizona Board Of Regents Acting On Behalf Of Arizona State University | Method for visualizing the base sequence of nucleic acid polymers |
| WO1991016675A1 (en) * | 1990-04-06 | 1991-10-31 | Applied Biosystems, Inc. | Automated molecular biology laboratory |
| DE69130396T2 (de) * | 1990-08-16 | 1999-06-24 | Genelabs Diagnostics Pte Ltd., Singapore | Vergrössertes western blot format und ein immunotestverfahren für die bestimmung von viralen antikörpern |
| WO1992015709A1 (en) | 1991-02-28 | 1992-09-17 | Abbott Laboratories | Scanning probe microscopy immunoassay |
| DE69212062T2 (de) * | 1991-04-30 | 1996-11-28 | Matsushita Electric Industrial Co., Ltd., Kadoma, Osaka | Raster-Abtastmikroskop, molekulares Verarbeitungsverfahren unter Verwendung des Mikroskops und Verfahren zum Wahrnehmen der DNA-Basen-Anordnung |
| US5138174A (en) * | 1991-07-16 | 1992-08-11 | E. I. Du Pont De Nemours And Company | Nanometer-scale structures and lithography |
| IL103674A0 (en) * | 1991-11-19 | 1993-04-04 | Houston Advanced Res Center | Method and apparatus for molecule detection |
| US5384261A (en) * | 1991-11-22 | 1995-01-24 | Affymax Technologies N.V. | Very large scale immobilized polymer synthesis using mechanically directed flow paths |
| GB9203037D0 (en) * | 1992-02-11 | 1992-03-25 | Salutar Inc | Contrast agents |
| US5445971A (en) * | 1992-03-20 | 1995-08-29 | Abbott Laboratories | Magnetically assisted binding assays using magnetically labeled binding members |
| US5519212A (en) * | 1992-08-07 | 1996-05-21 | Digital Instruments, Incorporated | Tapping atomic force microscope with phase or frequency detection |
| US5372930A (en) * | 1992-09-16 | 1994-12-13 | The United States Of America As Represented By The Secretary Of The Navy | Sensor for ultra-low concentration molecular recognition |
| JPH06124680A (ja) | 1992-10-12 | 1994-05-06 | Jeol Ltd | 2次中性粒子質量分析装置 |
| DE69320753T2 (de) * | 1992-11-06 | 1999-03-25 | Hitachi Construction Machinery Co., Ltd., Tokio/Tokyo | Rasterabtastmikroskop und Verfahren zur Steuerfehlerkorrektur |
| US5472881A (en) * | 1992-11-12 | 1995-12-05 | University Of Utah Research Foundation | Thiol labeling of DNA for attachment to gold surfaces |
| US5314829A (en) * | 1992-12-18 | 1994-05-24 | California Institute Of Technology | Method for imaging informational biological molecules on a semiconductor substrate |
| JP3270165B2 (ja) * | 1993-01-22 | 2002-04-02 | セイコーインスツルメンツ株式会社 | 表面分析及び加工装置 |
| US5346683A (en) * | 1993-03-26 | 1994-09-13 | Gas Research Institute | Uncapped and thinned carbon nanotubes and process |
| FR2703693B1 (fr) * | 1993-04-06 | 1995-07-13 | Pasteur Institut | Procédé rapide de détermination d'une séquence d'ADN et application au séquençage et au diagnostic. |
| US5837832A (en) * | 1993-06-25 | 1998-11-17 | Affymetrix, Inc. | Arrays of nucleic acid probes on biological chips |
| US5453970A (en) * | 1993-07-13 | 1995-09-26 | Rust; Thomas F. | Molecular memory medium and molecular memory disk drive for storing information using a tunnelling probe |
| WO1995006138A1 (en) * | 1993-08-25 | 1995-03-02 | The Regents Of The University Of California | Microscopic method for detecting micromotions |
| US5789167A (en) * | 1993-09-10 | 1998-08-04 | Genevue, Inc. | Optical detection of position of oligonucleotides on large DNA molecules |
| JP2526408B2 (ja) * | 1994-01-28 | 1996-08-21 | 工業技術院長 | カ―ボンナノチュ―ブの連続製造方法及び装置 |
| US5561043A (en) * | 1994-01-31 | 1996-10-01 | Trustees Of Boston University | Self-assembling multimeric nucleic acid constructs |
| FR2716263B1 (fr) * | 1994-02-11 | 1997-01-17 | Pasteur Institut | Procédé d'alignement de macromolécules par passage d'un ménisque et applications dans un procédé de mise en évidence, séparation et/ou dosage d'une macromolécule dans un échantillon. |
| US5666190A (en) * | 1994-04-12 | 1997-09-09 | The Board Of Trustees Of The Leland Stanford, Jr. University | Method of performing lithography using cantilever array |
| US5571639A (en) * | 1994-05-24 | 1996-11-05 | Affymax Technologies N.V. | Computer-aided engineering system for design of sequence arrays and lithographic masks |
| US6287850B1 (en) * | 1995-06-07 | 2001-09-11 | Affymetrix, Inc. | Bioarray chip reaction apparatus and its manufacture |
| US5807522A (en) * | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
| JP3523688B2 (ja) * | 1994-07-06 | 2004-04-26 | オリンパス株式会社 | 試料測定用プローブ装置 |
| US5604097A (en) * | 1994-10-13 | 1997-02-18 | Spectragen, Inc. | Methods for sorting polynucleotides using oligonucleotide tags |
| US6045671A (en) * | 1994-10-18 | 2000-04-04 | Symyx Technologies, Inc. | Systems and methods for the combinatorial synthesis of novel materials |
| US5985356A (en) * | 1994-10-18 | 1999-11-16 | The Regents Of The University Of California | Combinatorial synthesis of novel materials |
| US6004617A (en) * | 1994-10-18 | 1999-12-21 | The Regents Of The University Of California | Combinatorial synthesis of novel materials |
| US6203814B1 (en) * | 1994-12-08 | 2001-03-20 | Hyperion Catalysis International, Inc. | Method of making functionalized nanotubes |
| US5866434A (en) * | 1994-12-08 | 1999-02-02 | Meso Scale Technology | Graphitic nanotubes in luminescence assays |
| US5601982A (en) * | 1995-02-07 | 1997-02-11 | Sargent; Jeannine P. | Method and apparatus for determining the sequence of polynucleotides |
| US6239273B1 (en) * | 1995-02-27 | 2001-05-29 | Affymetrix, Inc. | Printing molecular library arrays |
| SE9501236D0 (sv) | 1995-04-04 | 1995-04-04 | Sven Oscarsson | Metod för kvantitativ och kvalitativ och kvalitativ diagnosticering av analyter med STM/SFM |
| US5545531A (en) * | 1995-06-07 | 1996-08-13 | Affymax Technologies N.V. | Methods for making a device for concurrently processing multiple biological chip assays |
| DE69638269D1 (de) * | 1995-06-14 | 2010-11-18 | Univ California | Hochaffine humane antikörper gegen tumorantigene |
| FR2737574B1 (fr) | 1995-08-03 | 1997-10-24 | Pasteur Institut | Appareillage d'alignement parallele de macromolecules et utilisation |
| US6518168B1 (en) * | 1995-08-18 | 2003-02-11 | President And Fellows Of Harvard College | Self-assembled monolayer directed patterning of surfaces |
| US6200737B1 (en) * | 1995-08-24 | 2001-03-13 | Trustees Of Tufts College | Photodeposition method for fabricating a three-dimensional, patterned polymer microstructure |
| US5851769A (en) * | 1995-09-27 | 1998-12-22 | The Regents Of The University Of California | Quantitative DNA fiber mapping |
| US5874668A (en) * | 1995-10-24 | 1999-02-23 | Arch Development Corporation | Atomic force microscope for biological specimens |
| CA2235395A1 (en) | 1995-11-13 | 1997-05-22 | Institut Pasteur | Ultrahigh resolution comparative nucleic acid hybridization to combed dna fibers |
| SE9504046D0 (sv) * | 1995-11-14 | 1995-11-14 | Pharmacia Ab | Method of determining affinity and kinetic properties |
| US6080586A (en) * | 1996-04-05 | 2000-06-27 | California Institute Of Technology | Sub-micron chemical imaging with near-field laser desorption |
| JP2000516708A (ja) | 1996-08-08 | 2000-12-12 | ウィリアム・マーシュ・ライス・ユニバーシティ | ナノチューブ組立体から作製された巨視的操作可能なナノ規模の装置 |
| US5981733A (en) * | 1996-09-16 | 1999-11-09 | Incyte Pharmaceuticals, Inc. | Apparatus for the chemical synthesis of molecular arrays |
| FR2755149B1 (fr) | 1996-10-30 | 1999-01-15 | Pasteur Institut | Procede de diagnostic de maladies genetiques par peignage moleculaire et coffret de diagnostic |
| US6024925A (en) * | 1997-01-23 | 2000-02-15 | Sequenom, Inc. | Systems and methods for preparing low volume analyte array elements |
| US6180114B1 (en) * | 1996-11-21 | 2001-01-30 | University Of Washington | Therapeutic delivery using compounds self-assembled into high axial ratio microstructures |
| JP4663824B2 (ja) * | 1996-12-31 | 2011-04-06 | ハイ スループット ジェノミクス インコーポレイテッド | 多重化分子分析装置および方法 |
| US5753088A (en) * | 1997-02-18 | 1998-05-19 | General Motors Corporation | Method for making carbon nanotubes |
| US5763768A (en) * | 1997-03-17 | 1998-06-09 | Iowa State University Research Foundation, Inc. | Analytical method using modified scanning probes |
| US6231744B1 (en) * | 1997-04-24 | 2001-05-15 | Massachusetts Institute Of Technology | Process for fabricating an array of nanowires |
| US6203983B1 (en) * | 1997-06-16 | 2001-03-20 | Affymetrix, Inc. | Method for detecting chemical interactions between naturally occurring bio-polymers which are non-identical binding partners |
| NZ502246A (en) * | 1997-06-20 | 2002-10-25 | Univ New York | Electrospraying solutions of biologically active substances (proteins) on a substrate for mass fabrication of chips and libraries |
| US5993627A (en) * | 1997-06-24 | 1999-11-30 | Large Scale Biology Corporation | Automated system for two-dimensional electrophoresis |
| US20020114987A1 (en) | 1997-09-24 | 2002-08-22 | Sven Oscarsson | Method of arraying nanoparticles and macromolecules on surfaces |
| US6123819A (en) * | 1997-11-12 | 2000-09-26 | Protiveris, Inc. | Nanoelectrode arrays |
| CN1285001A (zh) | 1997-12-18 | 2001-02-21 | 塞普拉科有限公司 | 同时鉴定新型生物靶和用于药物开发的引导结构的方法 |
| US6309831B1 (en) * | 1998-02-06 | 2001-10-30 | Affymetrix, Inc. | Method of manufacturing biological chips |
| US6033911A (en) * | 1998-02-27 | 2000-03-07 | Hamilton Company | Automated assaying device |
| US6087274A (en) * | 1998-03-03 | 2000-07-11 | The United States Of America As Represented By The Secretary Of The Navy | Nanoscale X-Y-Z translation of nanochannel glass replica-based masks for making complex structures during patterning |
| US6146899A (en) * | 1998-03-13 | 2000-11-14 | Iowa State University Research Foundation, Inc. | Height referencing biochemical cassette |
| JP3902883B2 (ja) * | 1998-03-27 | 2007-04-11 | キヤノン株式会社 | ナノ構造体及びその製造方法 |
| US6284497B1 (en) * | 1998-04-09 | 2001-09-04 | Trustees Of Boston University | Nucleic acid arrays and methods of synthesis |
| US6255469B1 (en) * | 1998-05-06 | 2001-07-03 | New York University | Periodic two and three dimensional nucleic acid structures |
| US5992226A (en) * | 1998-05-08 | 1999-11-30 | The United States Of America As Represented By The Secretary Of The Navy | Apparatus and method for measuring intermolecular interactions by atomic force microscopy |
| US6159742A (en) * | 1998-06-05 | 2000-12-12 | President And Fellows Of Harvard College | Nanometer-scale microscopy probes |
| US6218122B1 (en) * | 1998-06-19 | 2001-04-17 | Rosetta Inpharmatics, Inc. | Methods of monitoring disease states and therapies using gene expression profiles |
| US6406921B1 (en) | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
| US6576478B1 (en) | 1998-07-14 | 2003-06-10 | Zyomyx, Inc. | Microdevices for high-throughput screening of biomolecules |
| US7416699B2 (en) | 1998-08-14 | 2008-08-26 | The Board Of Trustees Of The Leland Stanford Junior University | Carbon nanotube devices |
| US6214552B1 (en) * | 1998-09-17 | 2001-04-10 | Igen International, Inc. | Assays for measuring nucleic acid damaging activities |
| EP1115737A4 (en) * | 1998-09-23 | 2004-11-24 | Cleveland Clinic Foundation | NEW GENES STIMULATED OR REPRESSED BY INTERFERON |
| US6232706B1 (en) * | 1998-11-12 | 2001-05-15 | The Board Of Trustees Of The Leland Stanford Junior University | Self-oriented bundles of carbon nanotubes and method of making same |
| JP2002536295A (ja) | 1998-12-14 | 2002-10-29 | パラチン テクノロジーズ, インク. | 金属ペプチド組合せライブラリ及びその利用法 |
| US6827979B2 (en) | 1999-01-07 | 2004-12-07 | Northwestern University | Methods utilizing scanning probe microscope tips and products therefor or produced thereby |
| US6635311B1 (en) | 1999-01-07 | 2003-10-21 | Northwestern University | Methods utilizing scanning probe microscope tips and products therefor or products thereby |
| US20020122873A1 (en) | 2000-01-05 | 2002-09-05 | Mirkin Chad A. | Nanolithography methods and products therefor and produced thereby |
| US5958701A (en) * | 1999-01-27 | 1999-09-28 | The United States Of America As Represented By The Secretary Of The Navy | Method for measuring intramolecular forces by atomic force |
| WO2000046406A2 (en) | 1999-02-05 | 2000-08-10 | Alphagene, Inc. | Arrays for investigating protein protein interactions |
| US6270946B1 (en) * | 1999-03-18 | 2001-08-07 | Luna Innovations, Inc. | Non-lithographic process for producing nanoscale features on a substrate |
| US6289717B1 (en) * | 1999-03-30 | 2001-09-18 | U. T. Battelle, Llc | Micromechanical antibody sensor |
| US6573369B2 (en) | 1999-05-21 | 2003-06-03 | Bioforce Nanosciences, Inc. | Method and apparatus for solid state molecular analysis |
| US20020042081A1 (en) | 2000-10-10 | 2002-04-11 | Eric Henderson | Evaluating binding affinities by force stratification and force panning |
| US20010044106A1 (en) * | 1999-05-21 | 2001-11-22 | Eric Henderson | Method and apparatus for solid state molecular analysis |
| US6420105B1 (en) * | 1999-08-13 | 2002-07-16 | University Of Kentucky Research Foundation | Method for analyzing molecular expression or function in an intact single cell |
| US6395554B1 (en) * | 1999-09-03 | 2002-05-28 | Packard Instrument Company | Microarray loading/unloading system |
| US6171797B1 (en) * | 1999-10-20 | 2001-01-09 | Agilent Technologies Inc. | Methods of making polymeric arrays |
| US6399295B1 (en) * | 1999-12-17 | 2002-06-04 | Kimberly-Clark Worldwide, Inc. | Use of wicking agent to eliminate wash steps for optical diffraction-based biosensors |
| SE0000546D0 (sv) | 2000-02-18 | 2000-02-18 | Sven Oscarsson | Method for the positioning of marcromolecules and particles |
| US6897015B2 (en) | 2000-03-07 | 2005-05-24 | Bioforce Nanosciences, Inc. | Device and method of use for detection and characterization of pathogens and biological materials |
| EP1348113B1 (en) | 2000-08-15 | 2008-07-30 | Bioforce Nanosciences, Inc. | Nanoscale molecular arrayer |
| AU2002211807A1 (en) | 2000-09-11 | 2002-03-26 | Massachusetts Institute Of Technology | Direct haplotyping using carbon nanotube probes |
| AU2002337637A1 (en) | 2001-01-26 | 2003-01-08 | Northwestern University | Method and device utilizing driving force to deliver deposition compound |
| US6642129B2 (en) | 2001-07-26 | 2003-11-04 | The Board Of Trustees Of The University Of Illinois | Parallel, individually addressable probes for nanolithography |
| WO2003038033A2 (en) | 2001-10-02 | 2003-05-08 | Northwestern University | Protein and peptide nanoarrays |
| EP1461596B1 (en) | 2001-11-30 | 2013-07-17 | Northwestern University | Direct write nanolithographic deposition of nucleic acids from nanoscopic tips |
| EP1502154B1 (en) | 2001-12-17 | 2009-02-18 | Northwestern University | Patterning of solid state features by direct write nanolithographic printing |
-
2002
- 2002-05-30 US US10/160,372 patent/US6897015B2/en not_active Expired - Lifetime
-
2003
- 2003-05-29 CN CNA038118688A patent/CN1656236A/zh active Pending
- 2003-05-29 JP JP2004508645A patent/JP2005527830A/ja active Pending
- 2003-05-29 EP EP03734244A patent/EP1513954A4/en not_active Ceased
- 2003-05-29 KR KR1020047019317A patent/KR20050026395A/ko not_active Withdrawn
- 2003-05-29 WO PCT/US2003/016860 patent/WO2003101278A2/en not_active Ceased
- 2003-05-29 AU AU2003238783A patent/AU2003238783A1/en not_active Abandoned
- 2003-05-29 CA CA002487792A patent/CA2487792A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003101278A2 (en) | 2003-12-11 |
| AU2003238783A1 (en) | 2003-12-19 |
| WO2003101278A3 (en) | 2004-09-30 |
| US6897015B2 (en) | 2005-05-24 |
| CA2487792A1 (en) | 2003-12-11 |
| EP1513954A2 (en) | 2005-03-16 |
| US20020172943A1 (en) | 2002-11-21 |
| EP1513954A4 (en) | 2005-10-19 |
| JP2005527830A (ja) | 2005-09-15 |
| KR20050026395A (ko) | 2005-03-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US6897015B2 (en) | Device and method of use for detection and characterization of pathogens and biological materials | |
| Poghossian et al. | Field-effect sensors for virus detection: From Ebola to SARS-CoV-2 and plant viral enhancers | |
| Payne | Methods to study viruses | |
| CN102483412B (zh) | 用于病毒抗原的直接荧光免疫测定 | |
| JP4866462B2 (ja) | マイクロアレイシステム、およびマイクロアレイの製造方法 | |
| Nettikadan et al. | Virus particle detection by solid phase immunocapture and atomic force microscopy | |
| JP2005535870A (ja) | ファージリガンドセンサーデバイスおよびその使用 | |
| Basso et al. | Fast and reliable detection of SARS-CoV-2 antibodies based on surface plasmon resonance | |
| CN101592626A (zh) | 准一维金属氧化物纳米材料生物传感器及其制作方法 | |
| US7569340B2 (en) | Nanoarrays of single virus particles, methods and instrumentation for the fabrication and use thereof | |
| Pavlickova et al. | Antibody detection in human serum using a versatile protein chip platform constructed by applying nanoscale self-assembled architectures on gold | |
| Gulati et al. | Immunoelectron microscopy of viral antigens | |
| CN102605099A (zh) | 一种猪病毒基因芯片及其检测方法 | |
| CN101629955B (zh) | 鱼类淋巴囊肿病毒免疫检测芯片及其制备方法与应用 | |
| CN101477117B (zh) | 检测禽病血清抗体的可视化蛋白芯片及其制备方法和应用 | |
| US20210302418A1 (en) | Ultrasensitive detection of virus particles and virus-like particles | |
| EP1622500A4 (en) | PARALLEL ANALYSIS OF MOLECULAR INTERACTIONS | |
| US20240319186A1 (en) | Nanowire-based immunofluorescence kit for detecting sars coronavirus 2 antibody, and use thereof | |
| WO2007011405A2 (en) | Device and method of use for detection and characterization of microorganisms and microparticles | |
| TWI776258B (zh) | 生物活性組成試片結構及其檢測方法 | |
| Huang et al. | Detection of duck hepatitis virus serotype1 by biosensor based on imaging ellipsometry | |
| Wang et al. | Preparation of a visual protein chip for detection of IgG against Treponema pallidum | |
| RU2339036C2 (ru) | Способ оценки качества вакцин | |
| RU2267787C2 (ru) | Способ детекции токсичных белков на основе сканирующей зондовой микроскопии | |
| Ivanov et al. | Atomic force microscopy detection of serological markers of viral hepatites B and C |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |