CN1634209A - Pharmaceutical composition for treating angioneurotic migraine - Google Patents
Pharmaceutical composition for treating angioneurotic migraine Download PDFInfo
- Publication number
- CN1634209A CN1634209A CN 200310122492 CN200310122492A CN1634209A CN 1634209 A CN1634209 A CN 1634209A CN 200310122492 CN200310122492 CN 200310122492 CN 200310122492 A CN200310122492 A CN 200310122492A CN 1634209 A CN1634209 A CN 1634209A
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- CN
- China
- Prior art keywords
- pharmaceutical composition
- rhizoma chuanxiong
- angelicae dahuricae
- herba asari
- mixing
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Abstract
The invention relates to a pharmaceutical composition for treating angioneurotic migraine, which is prepared from Chinese medicinal herbs including Ligusticum wallichii, dahurian angelica root and asarum, which can be prepared into the dose forms of granule, capsule, tablet, water-paste pill, injection and ointment.
Description
The present invention relates to treat the pharmaceutical composition of angioneurotic headache, the invention still further relates to the preparation method of this medicine.
Pharmaceutical composition of the present invention mainly contains following component and makes: (consumption is a weight portion)
Rhizoma Chuanxiong 1-30 Radix Angelicae Dahuricae 1-30 Herba Asari 1-30
The formula optimization weight portion ratio range of pharmaceutical composition of the present invention is:
Rhizoma Chuanxiong 9-30 Radix Angelicae Dahuricae 1-9 Herba Asari 1-9
Most preferably weight (part) proportioning of pharmaceutical composition of the present invention is:
Rhizoma Chuanxiong 30 Radixs Angelicae Dahuricae 1 Herba Asari 1
Pharmaceutical composition of the present invention adopts routine techniques, adds conventional adjuvant or excipient, preferably make to be fit to oral dosage form, for example, granule, capsule, tablet and watered pill; Pharmaceutical composition of the present invention is preferably made injection, ointment.
Embodiment 1. granules
Prescription:
Rhizoma Chuanxiong 30 Radixs Angelicae Dahuricae 1 Herba Asari 1
Production method 1: three flavor medical materials such as Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Herba Asari are ground into coarse powder earlier, decoct with water twice, and each 1 hour, collecting decoction filtered.Filtrate is concentrated into thick paste, oven dry, and the broken fine powder I that gets of dried cream powder adds auxiliary materials and mixing, alcohol granulation, airpillow-dry, granulate, mixing, promptly.
Production method 2: three flavor medical materials such as Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Herba Asari are ground into coarse powder earlier, decoct with water twice, and each 1 hour, collecting decoction filtered.When filtrate volume is concentrated into required amount (medical material weight mg: concentrated solution volume ml is 1: 1), adding 95% ethanol to concentration is 70%, precipitate with ethanol, filter, filtrate is concentrated into the thick paste that relative density is 1.30-1.35 (50 ℃), oven dry, the broken fine powder I that gets of dried cream powder, add auxiliary materials and mixing, alcohol granulation, airpillow-dry, granulate, mixing, promptly.
Embodiment 2: capsule
Press example 1 affiliated proportioning and technology with fine powder I and suitable excipient mixing, mixing is filled and is made capsule.
Embodiment 3: tablet
By example 1 described proportioning and technology fine powder I is added appropriate amount of auxiliary materials (as dextrin, dry starch, magnesium stearate etc.), alcohol granulation, drying, compacting is in flakes.
Embodiment 4: the watered pill
By example 1 described proportioning and technology fine powder I and water are placed mixing in general ball pot or other container, make wet-milling, pressed No. two sieve series to become granule, granule is put into the spin friction of general ball pot again, wound goes corner angle circular, makes the watered pill.
Embodiment 5: injection
Press example 1 described proportioning and technology with fine powder I, add solvent and make its dissolving, add solvent to 1000ml, regulate pH value, filtration, perfusion, sealing by fusing, sterilization, quality testing are promptly.
Embodiment 6: ointment
Press example 1 described proportioning and technology with fine powder I, add an amount of dextrin mix homogeneously and be ground to no granular sensation, gradation adds with in the substrate (as vaseline, tween 80, Polyethylene Glycol etc.) of melting, and the limit edged is stirred to condensation, makes ointment.
Claims (8)
1. treat angioneurotic migrainous pharmaceutical composition for one kind, it is characterized in that comprising the raw material of following weight portion:
Pharmaceutical composition of the present invention is mainly made by following component: (consumption is a weight portion)
Rhizoma Chuanxiong 1-30 Radix Angelicae Dahuricae 1-30 Herba Asari 1-30
2. pharmaceutical composition according to claim 1 is characterized in that the weight proportion of contained primary raw material is:
Rhizoma Chuanxiong 9-30 Radix Angelicae Dahuricae 1-9 Herba Asari 1-9
3. pharmaceutical composition according to claim 1 is characterized in that the optimum weight proportioning of contained primary raw material is:
Rhizoma Chuanxiong 30 Radixs Angelicae Dahuricae 1 Herba Asari 1
4. according to the described pharmaceutical composition of one of claim 1-3, it is characterized in that said medicament can be said any dosage form on the pharmaceutics.
5. pharmaceutical composition according to claim 4 is characterized in that it can being granule, capsule, tablet, watered pill, injection, ointment.
6. pharmaceutical composition according to claim 4 is characterized in that said dosage form can be mixed and made into any adjuvant on the pharmaceutics.
7. according to the described preparation of drug combination method 1 of one of claim 1-3, it is characterized in that:
Three flavor medical materials such as Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Herba Asari are ground into coarse powder earlier, decoct with water twice, and each 1 hour, collecting decoction filtered.Filtrate is concentrated into thick paste, oven dry, and the broken fine powder that gets of dried cream powder adds auxiliary materials and mixing, alcohol granulation, airpillow-dry, granulate, mixing, promptly.
8. according to the described preparation of drug combination method 2 of one of claim 1-3, it is characterized in that:
Three flavor medical materials such as Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, Herba Asari are ground into coarse powder earlier, decoct with water twice, and each 1 hour, collecting decoction filtered.When filtrate volume is concentrated into required amount (medical material weight mg: concentrated solution volume ml is 1: 1), adding 95% ethanol to concentration is 70%, precipitate with ethanol, filter, filtrate is concentrated into the thick paste that relative density is 1.30-1.35 (50 ℃), oven dry, the broken fine powder IV that gets of dried cream powder, add auxiliary materials and mixing, alcohol granulation, airpillow-dry, granulate, mixing, promptly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2003101224923A CN1313105C (en) | 2003-12-26 | 2003-12-26 | Pharmaceutical composition for treating angioneurotic migraine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2003101224923A CN1313105C (en) | 2003-12-26 | 2003-12-26 | Pharmaceutical composition for treating angioneurotic migraine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1634209A true CN1634209A (en) | 2005-07-06 |
| CN1313105C CN1313105C (en) | 2007-05-02 |
Family
ID=34844534
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2003101224923A Expired - Fee Related CN1313105C (en) | 2003-12-26 | 2003-12-26 | Pharmaceutical composition for treating angioneurotic migraine |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1313105C (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102813839A (en) * | 2012-09-11 | 2012-12-12 | 张鹏 | Compound medicine for treating cluster headache syndrome |
| CN103251819A (en) * | 2012-12-23 | 2013-08-21 | 黄天双 | Nervous headache treatment traditional Chinese medicine composition |
| CN105079240A (en) * | 2014-05-13 | 2015-11-25 | 成都百草和济科技有限公司 | Medicine composition for treating hyperostosis |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1047532C (en) * | 1994-06-15 | 1999-12-22 | 王万树 | Anti-headache Chinese proprietary medicine and its preparing method |
| CN1051933C (en) * | 1995-04-19 | 2000-05-03 | 文渊 | Traditional Chinese medicine composition for treating refractory headache |
-
2003
- 2003-12-26 CN CNB2003101224923A patent/CN1313105C/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102813839A (en) * | 2012-09-11 | 2012-12-12 | 张鹏 | Compound medicine for treating cluster headache syndrome |
| CN102813839B (en) * | 2012-09-11 | 2013-10-23 | 张鹏 | Compound medicine for treating cluster headache syndrome |
| CN103251819A (en) * | 2012-12-23 | 2013-08-21 | 黄天双 | Nervous headache treatment traditional Chinese medicine composition |
| CN105079240A (en) * | 2014-05-13 | 2015-11-25 | 成都百草和济科技有限公司 | Medicine composition for treating hyperostosis |
| CN105079240B (en) * | 2014-05-13 | 2018-10-16 | 成都百草和济科技有限公司 | A kind of pharmaceutical composition for treating osteoproliferation |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1313105C (en) | 2007-05-02 |
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| C06 | Publication | ||
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| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
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Granted publication date: 20070502 Termination date: 20121226 |