CN1628829B - Chinese medicine for treating hypertension, high blood fat and high blood sugar - Google Patents
Chinese medicine for treating hypertension, high blood fat and high blood sugar Download PDFInfo
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- CN1628829B CN1628829B CN 200410073874 CN200410073874A CN1628829B CN 1628829 B CN1628829 B CN 1628829B CN 200410073874 CN200410073874 CN 200410073874 CN 200410073874 A CN200410073874 A CN 200410073874A CN 1628829 B CN1628829 B CN 1628829B
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Abstract
Disclosed is a Chinese medicinal preparation for treating cardiovascular and cerebrovascular diseases, which is prepared by using matrimony vine, fleece-flower root, ginkgo as main components and other Chinese medicinal herbs. The preparation employs the procedures of ultra-fine powder water grilling, concentrating, and grease forming.
Description
Technical field
The present invention relates to the field of Chinese medicines, especially treat the field of Chinese medicines of cardiovascular and cerebrovascular disease.
Background technology
Entered since 21 century, along with socioeconomic fast development, the people's living standard improves constantly.Simultaneously, the factor such as increase the weight of of the quickening of the increasing of the change of dietary habit, bad habit, work rhythm and social pressure causes the sickness rate of various diseases to increase substantially.Especially " three-hypers " crowds such as hypertension, hyperlipidemia, hyperglycemia, caused human sub-health state ubiquity, according to Ministry of Public Health statistics whole nation in 2003 9000 ten thousand people are arranged approximately altogether, suffers from the easiest generation that causes diseases such as cerebral thrombosis, cerebral hemorrhage, coronary heart disease of crowd of above-mentioned " three-hypers ", and age of onset is rejuvenation day by day, caused global attention, cardiovascular and cerebrovascular disease has been classified as first killer of harm humans health by World Health Organization (WHO).According to statistics, nearly 32% people dies from cardiovascular and cerebrovascular disease in the annual death, not only human beings'health is caused great threat, has also increased the weight of social burden.
At present, it is not single disease that quite a few cardiovascular and cerebrovascular disease patient is arranged, but various disease conditions exists simultaneously.As suffering from hypertension, hyperlipidemia or hyperglycemia simultaneously.And market supply is the medicine of only treating single disease mostly, will take multiple medicine simultaneously for the patient who suffers from various disease conditions such as hypertension, hyperlipidemia, hyperglycemia simultaneously, has brought inconvenience to the patient.Some medicine also exists curative effect can not be lasting, has a rebound after the drug withdrawal, must for a long time continual shortcoming of taking.These problems affect the curative effect of medicine, increase financial burden to the patient.
Summary of the invention
Diseases such as hypertension, hyperlipidemia, hyperglycemia, the Chinese medicine of stable disease after the drug withdrawal can effectively be treated and treat to purpose of the present invention for providing a kind for the treatment of both the principal and secondary aspects of a disease effect lasting.
The prescription of Chinese medicine of the present invention is as follows: Radix Polygoni Multiflori 3-30 gram, Fructus Lycii 1-30 gram, Folium Ginkgo 3-60 gram, Fructus Mori 3-60 gram, Fructus Ligustri Lucidi 3-40 gram, Radix Angelicae Sinensis 3-20 gram, Rhizoma Chuanxiong 2-30 gram, Hirudo 0.5-4.5 gram, Pheretima 3-15 gram, Radix Salviae Miltiorrhizae 2-30 gram, Herba Apocyni veneti 2-30 gram, Herb Gynostemmae Pentaphylli 2-10 gram.
Contained Chinese crude drug in above-mentioned each prescription has following effect:
Radix Polygoni Multiflori: contain chrysophanic acid, gallic acid, Radix Polygoni Multiflori second element and third element, have blood fat reducing, arteriosclerosis, function in delaying senility.
Fructus Mori: contain tannic acid, malic acid, VB1, VB2, VB3 and carotene, have functions such as blood vessel dilating, nourishing YIN and supplementing blood, hypnotic, the intestine moistening of promoting the production of body fluid.
Fructus Ligustri Lucidi: contain oleanolic acid, ursolic acid and various trace elements, have blood sugar lowering, improve the effect of superoxide dismutase, also contain active substance such as nicotinic acid, aminoacid, be the main component that cell generates, can promote the metabolism of cell, recover young physiological status.
Fructus Lycii: be rich in several amino acids such as nicotinic acid, lycium barbarum polysaccharide, atropine, have the effect of expansion vessel softening, can blood circulation promoting and the interior refuse effect of eliminating body.
Folium Ginkgo: containing effective ingredient such as flavonoid glycoside, oleanolic acid, have and remove the interior lipid of being retarded by silt of blood vessel and the effect of cholesterol, is blood fat reducing good medicine.
Radix Angelicae Sinensis: contain nicotinic acid, angelic acid and volatile oil, have anticoagulant, antithrombotic and form, blood fat reducing, blood vessel dilating, blood pressure lowering, effects such as enhancing immunity have invigorating blood circulation, change the effect of blood.
Rhizoma Chuanxiong, Hirudo: have the arteriosclerosis of alleviating, stop the effect of platelet aggregation, be used to prevent and treat cerebral thrombosis and myocardial infarction.
Pheretima, Radix Salviae Miltiorrhizae: have activating blood and removing stasis, refrigerant pain relieving stops the effect of platelet aggregation.
Herba Apocyni veneti: have refrigerant, blood pressure lowering, the effect of diuresis of blood circulation promoting.
Herb Gynostemmae Pentaphylli: contain gallic acid, have the effect of blood fat reducing.
The present invention broken through the traditional Chinese medical science traditional " monarch, minister, help, make the medicine combination principle ", in conjunction with the modern Chinese medicine research theory, will have collaborative mutually Chinese medicine reasonable compatibility.Show from the above-mentioned effective ingredient that contains, it has been rich in flavonoid glycoside, oleanolic acid, nicotinic acid, gallic acid, vitamin C, B1, B2, various trace elements such as carotene and zinc-iron calcium, can expand vessel softening at short notice after taking, increase blood vessel elasticity, increase the blood vessel perfusion flow, reduce pressure to blood vessel wall, remove the lipid and the cholesterol that are retarded by silt in the blood vessel, promote to drain, suppress hematoblastic gathering, alleviating arteriosclerosis and antithrombotic forms, improve organ dysfunction, reach blood pressure regulation, blood fat reducing, the multi-functional effect of carrying out synchronously of blood sugar lowering one medicine, the base substance of additional a large amount of synthetic cells simultaneously, promote cell division, propagation, make cell development vigorous, improve super oxidasic activity, regulate organism physiology blood supply state, reach slow down aging, the effect of poliosis blackening and hair growth promoting.
Medicine of the present invention also has the effect for the treatment of both the principal and secondary aspects of a disease, can not only a medicine be multi-functional carries out synchronously with blood pressure regulation, blood fat reducing, blood sugar lowering etc., the softening hardened blood vessel of expansion is removed the absorption again, the mitigation symptoms that are retarded by silt in endovascular cholesterol, lipid and metabolite, retardance intestinal; And then recover the normal physiological function of each organs such as liver, kidney, the heart, brain, pancreas, keep the young state of organ to prevent the formation of new pathological changes.
Preparation method of the present invention is as follows:
(1) Fructus Lycii, Radix Angelicae Sinensis, Hirudo are worn into the micron-class superfine powder, standby;
(2) with Radix Polygoni Multiflori, Fructus Ligustri Lucidi breaking cellular wall, adding weight is the water of seven times of dosages, decocting 120 minutes, filter the back and extract filtrate, adding weight in filtering residue again is the duple water of dosage, carries out the decocting second time, extracts filtrate for the second time through 60-120 minute after-filtration, twice filtrate is mixed, standby;
(3) adding weight in all the other medical materials is the water of seven times of dosages, and decocting 120 minutes filters the back and extracts filtrate, adding weight in filtering residue again is the duple water of dosage, carries out the decocting second time, extracts filtrate for the second time through 60-120 minute after-filtration, twice filtrate is mixed, standby;
(4) the decocting liquid with above-mentioned steps (2), (3) gained mixes, and reconcentration is to three times of used medical material gross weight, and is standby;
(5) step (1) gained superfines is joined in the concentrated solution of step (4) gained, heat, concentrate, be concentrated to a times of used medical material gross weight, the gained mastic is stipulated packing on demand while stir to 100 ℃;
(6) each packaging cobalt
60Be finished medicines behind the radiation sterilization.
Medicine of the present invention in clinic trial 126 examples, wherein, man's 79 examples, women's 47 examples; Minimal ages 35 years old, at maximum 83 years old age, 45-60 year, 102 examples accounted for 80%; Hyperpietic's 33 examples wherein, hyperlipemic patients 73 examples, hyperglycemic patients 20 examples.Cerebral arteriosclerosis patient 80 examples wherein wherein suffer from patient's 39 examples of hypertension, hyperlipidemia, hyperglycemia simultaneously.The patient takes 15 grams at every turn, takes secondary every day, wherein has 109 examples (accounting for 86.5%) to take after 2-5 days dizzy, headache, sx or disappearance such as nervous, uncomfortable in chest.All the other 17 examples (accounting for 13.5%) have been taken sx or disappearance after 6-10 days, so total effective rate is 100%.Now taking per course of treatment is 15 days, checks blood pressure, blood fat, blood glucose, rheoencephalogram, electrocardiogram etc. after taking 1 course of treatment, and the state of an illness all has and significantly alleviates, the recovery that has normal, among cure rate is being added up at present.
Chinese medicine of the present invention through said method is made has following characteristics:
1, because has collaborative mutually Chinese medicine reasonable compatibility, auxilliary mutually the use, make hardened vasodilation softening, remove at endovascular cholesterol, lipid and metabolite being retarded by silt, and the absorption again in the retardance intestinal, finally reach the multi-functional effects of a medicine such as blood pressure regulation, blood fat reducing, blood sugar lowering.
2, can recover and improve the normal physiological function of each organs such as liver, kidney, the heart, brain, pancreas, prevent the formation of new pathological changes, prevent the disease bounce-back, curative effect is lasting, stable disease.
3, pack with the form of decoction, kept the advantage of Chinese medicine decoction, both made things convenient for patient to take, kept the useful effect of Chinese medicine again, take the back active substance and discharge rapidly, absorb fully definite effect.
The specific embodiment
Prescription: Radix Polygoni Multiflori 10 grams, Fructus Lycii 12 grams, Folium Ginkgo 15 grams, Fructus Mori 15 grams, Fructus Ligustri Lucidi 12 grams, Radix Angelicae Sinensis 10 grams, Rhizoma Chuanxiong 12 grams, Hirudo 2 grams, Pheretima 5 grams, Radix Salviae Miltiorrhizae 10 grams, Herba Apocyni veneti 10 grams, Herb Gynostemmae Pentaphylli 3 grams.
Preparation method:
(1) Fructus Lycii 12 grams, Radix Angelicae Sinensis 10 grams, Hirudo 2 grams are worn into the micron-class superfine powder, standby;
(2) with Radix Polygoni Multiflori 10 grams, Fructus Ligustri Lucidi 12 gram breaking cellular walls, add 150 ml waters, decocting 120 minutes, filter the back and extract filtrate, in filtering residue, add 45 ml waters again, carry out the decocting second time, after 60 minutes decoctings filter, extract filtrate for the second time, twice filtrate is mixed, standby;
(3) Folium Ginkgo 15 grams, Fructus Mori 15 grams, Rhizoma Chuanxiong 12 grams, Pheretima 5 grams, Radix Salviae Miltiorrhizae 10 grams, Herba Apocyni veneti 10 grams, Herb Gynostemmae Pentaphylli 3 grams are put together, add 500 ml waters, decocting 120 minutes, filter the back and extract filtrate, add 150 ml waters in filtering residue again, decocting 60 minutes filters the back and extracts filtrate for the second time, twice filtrate is mixed, standby;
(4) the decocting liquid of above-mentioned steps (2), (3) gained is mixed, reconcentration to 300 milliliter, standby;
(5) step (1) gained superfines is joined in the concentrated solution of step (4) gained, heat, concentrate, be concentrated to 116 milliliters, the gained mastic is carried out packing, whenever be packaged as the 12-15 gram while stir to 100 ℃;
(6) each packaging cobalt
60Be finished medicines behind the radiation sterilization.
Claims (2)
1. Chinese medicine for the treatment of hypertension, high blood fat and high blood sugar, contain Radix Polygoni Multiflori 3-30 gram, Fructus Lycii 1-30 gram, Folium Ginkgo 3-60 gram, Radix Angelicae Sinensis 3-20 gram, Rhizoma Chuanxiong 2-30 gram, Radix Salviae Miltiorrhizae 2-30 gram, Herb Gynostemmae Pentaphylli 2-10 gram in the prescription, it is characterized by and also contain Fructus Mori 3-60 gram, Fructus Ligustri Lucidi 3-40 gram, Hirudo 0.5-4.5 gram, Pheretima 3-15 gram, Herba Apocyni veneti 2-30 gram.
2. a kind of Chinese medicine for the treatment of hypertension, high blood fat and high blood sugar according to claim 1 is characterized by preparation method and is made up of following steps:
(1) Fructus Lycii, Radix Angelicae Sinensis, Hirudo are worn into the micron-class superfine powder, standby;
(2) with Radix Polygoni Multiflori, Fructus Ligustri Lucidi breaking cellular wall, adding weight is the water of seven times of dosages, decocting 120 minutes, filter the back and extract filtrate, adding weight in filtering residue again is the duple water of dosage, carries out the decocting second time, extracts filtrate for the second time through 60-120 minute after-filtration, twice filtrate is mixed, standby;
(3) adding weight in all the other medical materials is the water of seven times of dosages, and decocting 120 minutes filters the back and extracts filtrate, adding weight in filtering residue again is the duple water of dosage, carries out the decocting second time, extracts filtrate for the second time through 60-120 minute after-filtration, twice filtrate is mixed, standby;
(4) the decocting liquid with above-mentioned steps (2), (3) gained mixes, and reconcentration is to three times of used medical material gross weight, and is standby;
(5) superfines with step (1) gained joins in the concentrated solution of step (4) gained, heats to 100 ℃, concentrates while stir, and is concentrated to a times of used medical material gross weight, and the gained mastic is stipulated packing on demand;
(6) each packaging is finished medicines after boring 60 radiation sterilizations.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410073874 CN1628829B (en) | 2004-09-07 | 2004-09-07 | Chinese medicine for treating hypertension, high blood fat and high blood sugar |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410073874 CN1628829B (en) | 2004-09-07 | 2004-09-07 | Chinese medicine for treating hypertension, high blood fat and high blood sugar |
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| CN1628829A CN1628829A (en) | 2005-06-22 |
| CN1628829B true CN1628829B (en) | 2010-10-13 |
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| CN 200410073874 Expired - Fee Related CN1628829B (en) | 2004-09-07 | 2004-09-07 | Chinese medicine for treating hypertension, high blood fat and high blood sugar |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102526358B (en) * | 2012-02-13 | 2013-07-31 | 赵树刚 | Medicinal composition for treating diabetes and preparation method thereof |
| CN104857328A (en) * | 2015-04-24 | 2015-08-26 | 吴中区胥口精益生物医药研究所 | Blood sugar reducing traditional Chinese medicine white chrysanthemum, angelica dahurica, radix paeoniae alba, white poria cocos and gingko nut porridge and making method thereof |
| CN107568746B (en) * | 2017-10-16 | 2021-04-20 | 海南华研胶原科技股份有限公司 | Health food containing active peptide of marine shellfish and preparation method thereof |
| CN107828592A (en) * | 2017-12-05 | 2018-03-23 | 广西强象生物科技有限公司 | A kind of Moringa magma nutritious white spirit and its manufacture craft |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1329893A (en) * | 2000-06-16 | 2002-01-09 | 杨传平 | Chinese medicine for decreasing fat and lossing weight and preparation method thereof |
| CN1331992A (en) * | 2001-07-09 | 2002-01-23 | 江秉娥 | Chinese herbal medicine for treating hypertension |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1329893A (en) * | 2000-06-16 | 2002-01-09 | 杨传平 | Chinese medicine for decreasing fat and lossing weight and preparation method thereof |
| CN1331992A (en) * | 2001-07-09 | 2002-01-23 | 江秉娥 | Chinese herbal medicine for treating hypertension |
Non-Patent Citations (1)
| Title |
|---|
| CN 1329893 A,全文. |
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Granted publication date: 20101013 Termination date: 20190907 |