CN101869690B - Method for preparing traditional Chinese medicine for treating coronary artery disease with deficiency of both qi and yin - Google Patents

Abstract

The invention relates to a method for preparing a traditional Chinese medicine for treating the coronary artery disease with deficiency of both qi and yin, and belongs to the technical field of the preparation method of traditional Chinese medicines. At present, the coronary artery disease with deficiency of both qi and yin is treated by adopting transfusion or medicaments for oral administration; and if the coronary artery disease with deficiency of both qi and yin is treated by adopting propranolol, adverse reactions such as nausea, dizziness, blood pressure reduction and the like are easy to cause. The preparation method adopts the technical scheme by comprising the following steps of: immersing panax ginseng, large-headed atractylodes rhizome, astragalus, pseudostellaria root, Chinesedata, siberian solomonseal rhizome, bur beggarticks herb, levant cotton root, rehmanniae vaporata, Chinese angelica, white paeony root, longan flesh, peach seed, safflower, radix curcumae, szechuan lovage rhizome, root of red-rooted salvia, costustoot, rhizoma corydalis, fructus citri immaturus exsiccatus, trichosanthes kirilowii maxim and liquorice root into 1,200 milliliters of water for 30 minutes, decocting the traditional Chinese medicines over slow fire, and filtering the decocted liquid medicine by using gauze for deslagging to obtain 600 milliliters of liquid medicine, namely the traditional Chinese medicine for treating the coronary artery disease with deficiency of both qi and yin. The preparation method has the advantages of small side effect, little toxicity and high cure rate of Chinese medicinal liquid, convenient absorption in digestive tract after oral administration, stable treatment effect and difficult relapse of curative effect.

Description

A kind of Chinese medicinal preparation method for the treatment of coronary artery disease with deficiency of both qi and yin

Technical field

The present invention relates to the Chinese medicinal preparation method technical field, is a kind of Chinese medicinal preparation method for the treatment of coronary artery disease with deficiency of both qi and yin more specifically.

Background technology

Think that at present coronary artery disease with deficiency of both qi and yin belongs to the category of motherland's medical science " thoracic obstruction ".The thoracic obstruction is meant suffocating pain over the chest, chest pain radiating to the back very then, and a kind of disease that lose heart, failing to sleep due to dyspnea is primary symptom, the lighter only feels uncomfortable in chest as stops up, and breathes and owes smooth, and weight person then has chest pain, severe patient chest pain radiating to the back, backache radiating to the heart.The treatment coronary artery disease with deficiency of both qi and yin generally adopts transfusion or oral drug therapy at present.(1) as adopting Propranolol: cause nausea easily, giddy, dim eyesight, laxativeness, constipation, blood pressure drops, spirit depressing, fatigue and weak, insomnia etc., erythra, pharyngalgia, numbness of hand, visual disorder, hallucination etc. take place individually.Sinus bradycardia, atrioventricular block be can cause, heart failure or bronchial asthma brought out.The old people can have first dose of phenomenon, i.e. the dyspnea of medication generation first, collapse, shock etc.Respiration inhibition and laryngospasm etc. still can take place in intravenously administrable.(2) use metoprolol: gastrointestinal upset, stomachache, headache, dizzy, insomnia, nightmare, labour's type dyspnea, tired etc. can occur.(3) use digitaloid drugs: 1. gastrointestinal reaction can occur: as inappetence, nauseating, vomiting, idol has diarrhoea; 2. various arrhythmia can appear in the heart aspect, and modal is ventricular premature contraction or formation premature ventricular beat, occurs supraventricular tachycardia sometimes with atrioventricular block; 3. the nervous system aspect can occur headache, melancholy, unable and yellowly look or greenly look, blurred vision etc.(4) adopt nitroglycerin: can cause pulsatile headache, dizzy, dizzy.Vasodilation and pyroglossia, face's hyperemia, tachycardia, postural hypotension are arranged.Expand the ophthalmic blood vessel and increase intraocular pressure etc.

Summary of the invention

For overcoming above-mentioned shortcoming, the objective of the invention is to invent a kind of Chinese medicinal preparation method for the treatment of coronary artery disease with deficiency of both qi and yin.The clinical manifestation of coronary artery disease with deficiency of both qi and yin is: sensation of oppression and faint pain in the chest, in time, end when doing, shortness of breath and palpitation, tiredness with no desire to speak, lustreless complexion is had a dizzy spell, meet labor what for, reddish tongue or tongue with indented margins, thready and weak pulse without strength, or knot generation.Electrocardioscopy: deficiency myocardial blood supply.Blood test: numeration of leukocyte increases, and triglyceride increases.

Its technical scheme is: get Radix Ginseng 3 weight portions, the Rhizoma Atractylodis Macrocephalae 15 weight portions, the Radix Astragali 15 weight portions, Radix Ginseng 6 weight portions, Fructus Jujubae 9 weight portions, Rhizoma Polygonati 9 weight portions, Herba Bidentis Tripartitae 3 weight portions, Radix Gossypii 3 weight portions, Radix Rehmanniae Preparata 9 weight portions, Radix Angelicae Sinensis 9 weight portions, the Radix Paeoniae Alba 12 weight portions, Arillus Longan 12 weight portions, Semen Persicae 12 weight portions, Flos Carthami 9 weight portions, Radix Curcumae 9 weight portions, Rhizoma Chuanxiong 3 weight portions, Radix Salviae Miltiorrhizae 12 weight portions, the Radix Aucklandiae 9 weight portions, Rhizoma Corydalis 9 weight portions, Fructus Aurantii 9 weight portions, Fructus Trichosanthis 9 weight portions and Radix Glycyrrhizae 6 weight portions, above 22 flavor Chinese medicines are put into 1200 ml waters, soaked 30 minutes, slow fire is fried then, fried medicinal liquid with filtered through gauze remove slag 600 milliliters of medicinal liquids, be the Chinese medicine of treatment coronary artery disease with deficiency of both qi and yin.

The advantage of this invention is: make simply, this herb liquid side effect is little, and toxicity is little, the cure rate height.After oral, in digestive tract, be convenient to absorb.Therapeutical effect is stable, and curative effect is difficult for bounce-back.And avoided using untoward reaction and the toxic and side effects that Western medicine such as Propranolol, metoprolol, digitaloid drugs, nitroglycerin cause.Behind oral this Chinese medicine, can make the coronary artery disease with deficiency of both qi and yin disease obtain curing or taking a turn for the better.Radix Ginseng, the Rhizoma Atractylodis Macrocephalae, the Radix Astragali, Radix Ginseng, Fructus Jujubae, Rhizoma Polygonati, Herba Bidentis Tripartitae, Radix Gossypii, this 8 flavor medical instrument has the effect of invigorating the spleen and replenishing QI, and wherein Radix Ginseng again can emergency treatment of collapse, the antidiarrheal of promoting the production of body fluid, the benefit of allaying excitement knows; The Rhizoma Atractylodis Macrocephalae again can the dampness diuretic, strengthening superficial resistance to stop perspiration; The Radix Astragali again can yang invigorating, strengthening superficial resistance to stop perspiration, holder skin ulcer granulation promoting, inducing diuresis to remove edema; Radix Ginseng can promote the production of body fluid again; Fructus Jujubae again can He Ying, beneficial blood hemostasis, tranquilizing by nourishing the heart, the mitigation property of medicine; Rhizoma Polygonati again can nourishing YIN and moistening the lung; Herba Bidentis Tripartitae can heat clearing away disappear stagnant again.Radix Gossypii again can inrigorating qi and promoting blood circulation.Because of this 8 flavor medicine plays main therapeutical effect in the process of treatment coronary artery disease with deficiency of both qi and yin, so be monarch drug.Radix Rehmanniae Preparata, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Arillus Longan, Semen Persicae, Flos Carthami, Radix Curcumae, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae.Preceding 4 flavor medical instruments have the effect of YIN nourishing, blood-supplementing blood-nourishing, and wherein Radix Rehmanniae Preparata again can tonifying blood and regulating menstruation, the nourishing kidney nourishing YIN.Radix Angelicae Sinensis again can regulating menstruation, promoting blood circulation and stopping pain, loosening bowel to relieve constipation.The Radix Paeoniae Alba again can yin fluid astringing, easing the affected liver to relieve pain, yin nourishing suppressing the hyperactive liver.Arillus Longan again can nourishing blood to tranquillize the mind.Back 5 flavor medical instruments have blood circulation promoting and blood stasis dispelling, the effect of promoting the circulation of QI to relieve pain.More than 9 flavor medicines in the process of treatment coronary artery disease with deficiency of both qi and yin, can assist principal agent to bring into play therapeutical effect, so be ministerial drug.Ancients' cloud: " the capable then blood of gas is capable, and the stagnation of QI is blood clotting then." " qi being the governor of blood, blood being the material foundation of QI " promptly be this meaning.The Radix Aucklandiae, Rhizoma Corydalis, Fructus Aurantii, Fructus Trichosanthis, this 4 flavor medicine is promptly gone into blood system and is gone into edema caused by disorder of QI again, the gas in can promoting the circulation of blood, the blood in again can circulation of qi promoting.The gas promoting the circulation of blood is lived, general rule not bitterly, so be the good medicine of the promoting the circulation of QI pain relieving of invigorating blood circulation.Wherein the main component of Rhizoma Corydalis contains 15 kinds of alkaloids, and analgesic activity is arranged, and for the precordialgia due to the coronary heart disease, uses quite extensively, and curative effect is very prompt, can also make the Qi-tonifying drug tonify without causing stagnation, so be adjuvant drug.Radix Glycyrrhizae: sweet, flat, go into 12 warps.The spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.Can separate its toxicity, can entangle its bias again, so be messenger drug.More than 22 flavor medicine compatibilities use, have invigorating the spleen and replenishing QI, replenishing blood for nourishing heart, blood circulation promoting and blood stasis dispelling, the effect of promoting the circulation of QI to relieve pain is best Chinese medicine preparations of treatment coronary artery disease with deficiency of both qi and yin.Radix Ginseng: sweet, little sweet, tepor.Go into spleen, lung meridian, the QI invigorating emergency treatment of collapse is mended strengthening spleen and lung, promoting the production of body fluid to quench thirst, the mind calming and mentality promoting.The Rhizoma Atractylodis Macrocephalae: sweet, bitter, temperature.Go into spleen, stomach warp, invigorating the spleen and replenishing QI, the dampness diuretic is because of the table hidroschesis.The Radix Astragali: sweet, warm, go into spleen, lung meridian, tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, holder skin ulcer granulation promoting, inducing diuresis to remove edema.Radix Ginseng: sweet, little hardship, tepor.Go into spleen, lung meridian, supplementing QI for promoting the production of body fluid.Fructus Jujubae: sweet, bitter, temperature.Go into spleen, stomach, the heart, Liver Channel.Spleen reinforcing and battalion, beneficial blood hemostasis, tranquilizing by nourishing the heart relaxes the property of medicine.Rhizoma Polygonati: sweet, hardship, flat.Go into spleen, lung, kidney channel.Invigorating the spleen and replenishing QI, nourishing YIN and moistening the lung.Herba Bidentis Tripartitae: hardship, flat.Go into spleen, lung, large intestine channel.QI invigorating, heat clearing away disappears stagnant.Radix Gossypii: sweet, temperature is gone into spleen, liver, lung meridian.QI replenishing and blood harmonizing.Radix Rehmanniae Preparata: hardship, tepor.Go into the heart, liver, kidney channel.Tonifying blood and regulating menstruation, the nourishing kidney nourishing YIN.Radix Angelicae Sinensis: sweet, hot, bitter, warm.Go into liver, the heart, spleen channel, tonifying blood and regulating menstruation, promoting blood circulation and stopping pain, loosening bowel to relieve constipation.The Radix Paeoniae Alba: hardship, acid is slightly cold, and goes into liver, spleen channel.The yin fluid astringing of enriching blood, easing the affected liver to relieve pain, yin nourishing suppressing the hyperactive liver.Arillus Longan: sweet, flat, go into the heart, spleen channel, nourishing blood to tranquillize the mind.Semen Persicae: bitter, sweet, flat.Go into the heart, liver, large intestine channel.Laxation is moisturized in the removing blood stasis with potent drugs promoting the circulation of blood.Flos Carthami: suffering, temperature.Go into the heart, Liver Channel.Promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing.Radix Curcumae: hot, bitter, cold.Go into the heart, lung, liver, gallbladder meridian.The circulation of qi promoting blood stasis dispelling, heart fire-clearing upset-relieving.Rhizoma Chuanxiong: hot, warm.Go into liver, gallbladder, pericardium channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.Radix Salviae Miltiorrhizae: hardship is slightly cold.Go into the heart, Liver Channel.Blood circulation promoting and blood stasis dispelling, relieving restlessness is calmed the nerves, reducing swelling and alleviating pain.The Radix Aucklandiae: hot, bitter, temperature.Go into spleen, stomach, large intestine, tri-jiao channel, promoting the circulation of QI to relieve pain, invigorating the stomach and promoting digestion.Rhizoma Corydalis: hot, bitter, temperature.Go into liver, spleen, heart channel.Promoting blood circulation to remove blood stasis, the promoting the circulation of QI pain relieving.Fructus Aurantii: hardship is slightly cold.Go into spleen, stomach, large intestine channel.The dispelling the stagnated QI removing food stagnancy, circulation of qi promoting removes painful abdominal mass.Fructus Trichosanthis: sweet, cold.Go into spleen, stomach, large intestine channel.Removing heat-phlegm, relieving epigastric distention and reducing the stagnation, carbuncle, loosening bowel to relieve constipation are treated in detumescence.Radix Glycyrrhizae: sweet, flat.12 warps unable to make ends meet.The spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.

The specific embodiment

Get Radix Ginseng 3g, Rhizoma Atractylodis Macrocephalae 15g, Radix Astragali 15g, Radix Ginseng 6g, Fructus Jujubae 9g, Rhizoma Polygonati 9g, Herba Bidentis Tripartitae 3g, Radix Gossypii 3g, Radix Rehmanniae Preparata 9g, Radix Angelicae Sinensis 9g, Radix Paeoniae Alba 12g, Arillus Longan 12g, Semen Persicae 12g, Flos Carthami 9g, Radix Curcumae 9g, Rhizoma Chuanxiong 3g, Radix Salviae Miltiorrhizae 12g, Radix Aucklandiae 9g, Rhizoma Corydalis 9g, Fructus Aurantii 9g, Fructus Trichosanthis 9g and Radix Glycyrrhizae 6g, above 22 flavor Chinese medicines are put into 1200 ml waters, soaked 30 minutes, slow fire is fried then, fried medicinal liquid with filtered through gauze remove slag 600 milliliters of medicinal liquids, be the Chinese medicine of treatment coronary artery disease with deficiency of both qi and yin.When the patient of coronary artery disease with deficiency of both qi and yin need treat, make fluid temperature be 36 ℃, oral, each 300 milliliters, a twice-daily, three is a course of treatment, if still have symptom, oral again second course of treatment is so that recovery from illness.

Among the patient of 315 routine coronary artery disease with deficiency of both qi and yin, cure 305 examples, account for 96.83%; 8 examples that take a turn for the better account for 2.54%; Invalid 2 examples account for 0.63%.Wherein male's 139 examples account for 44.13%; Women's 176 examples account for 55.87%.The treatment natural law is the longest 63 days, the shortest 3 days.Wherein treat 7～14 days persons, 297 examples account for 94.29%.

Table one: 315 routine coronary artery disease with deficiency of both qi and yin patients show the course of treatment

The treatment natural law	3	4～6	7～14	15～63
					The example number	3	9	297	6
Percentage ratio	0.95％	2.86％	94.29％	1.90％

Table two: 315 routine coronary artery disease with deficiency of both qi and yin patient age scopes

Age (year)	9～15	16～30	31～51	52～72
					The example number	1	8	271	35
Percentage ratio	0.32％	2.54％	86.03％	11.11％

Table three: information slip before and after the 315 routine coronary artery disease with deficiency of both qi and yin patient

Claims (1)

1. Chinese medicinal preparation method for the treatment of coronary artery disease with deficiency of both qi and yin, it is characterized in that: get Radix Ginseng 3 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, the Radix Astragali 15 grams, Radix Ginseng 6 grams, Fructus Jujubae 9 grams, Rhizoma Polygonati 9 grams, Herba Bidentis Tripartitae 3 grams, Radix Gossypii 3 grams, Radix Rehmanniae Preparata 9 grams, Radix Angelicae Sinensis 9 grams, the Radix Paeoniae Alba 12 grams, Arillus Longan 12 grams, Semen Persicae 12 grams, Flos Carthami 9 grams, Radix Curcumae 9 grams, Rhizoma Chuanxiong 3 grams, Radix Salviae Miltiorrhizae 12 grams, the Radix Aucklandiae 9 grams, Rhizoma Corydalis 9 grams, Fructus Aurantii 9 grams, Fructus Trichosanthis 9 grams and Radix Glycyrrhizae 6 grams, above 22 flavor Chinese medicines are put into 1200 ml waters, soaked 30 minutes, slow fire is fried then, fried medicinal liquid with filtered through gauze remove slag 600 milliliters of medicinal liquids, be the Chinese medicine of treatment coronary artery disease with deficiency of both qi and yin.