CN1626220A

CN1626220A - Chinese herbal medicine for treating hyperthyroidism

Info

Publication number: CN1626220A
Application number: CN 200410050236
Authority: CN
Inventors: 赵立明
Original assignee: Individual
Current assignee: Individual
Priority date: 2004-08-12
Filing date: 2004-08-12
Publication date: 2005-06-15
Anticipated expiration: 2024-08-12
Also published as: CN1273181C

Abstract

A Chinese medicine for treating thyroidism is prepared from 15 Chinese-medicinal materials including astragalus root, red sage root, Chinese angelica root, rehmannia root, etc. Its advantaegs arc high curative effect and cure rate, and no toxic by-effect.

Description

A kind of Chinese herbal medicine for the treatment of hyperthyroidism

Technical field

The invention belongs to medical technical field, particularly the Chinese herbal medicine of treatment hyperthyroidism.

Background technology

Hyperthyroidism is because a kind of endocrinopathy due to the thyroid supersecretion.Show as nerve excitability clinically and increase, symptom such as the body oxidizing process is quickened and tissue metabolism is hyperfunction.Simultaneously with diffuse type thyromegaly or nodular type goiter.At present, adopt thiamazole, the treatment of hyperthyroidism equality, but easily cause leukopenia and erythra, toxic and side effects such as gastrointestinal reaction.And the employing treatment by Chinese herbs, its curative effect is also not really desirable.Add flavor treatment hyperthyroidism 36 routine observation of curative effect (Qu Zhongcan, Yunnan Chinese medicine magazine was rolled up 13 pages of the 3rd phases in 2002 23) as ZAOYAO SAN, cure 16 examples, 17 examples that take a turn for the better, invalid 3 examples, total effective rate is 91.66%.And for example soothing the liver soup treatment hyperthyroidism 32 examples of becoming thin (Zhang Zhi's Polygonum, the 26th page of practical Chinese medicine magazine 17 9 phase of volume of calendar year 2001).16 examples are cured in record, produce effects 9 examples, and 4 examples that take a turn for the better, invalid 3 examples, total effective rate is 90.6%.At present, also do not treat the specific drug of hyperthyroidism.

Summary of the invention

The purpose of this invention is to provide a kind of curative effect height, have no side effect, the Chinese herbal medicine of taking convenience treatment hyperthyroidism.

The present invention is achieved in that a kind of Chinese herbal medicine for the treatment of hyperthyroidism, and it comprises following component and content (weight ratio): Radix Astragali 25-80 part, Radix Codonopsis 10-40 part, Radix Salviae Miltiorrhizae 8-20 part, Sargassum 10-20 part, Thallus Laminariae (Thallus Eckloniae) 10-20 part, Spica Prunellae 10-20 part, Concha Ostreae 20-30 part, Bulbus Fritillariae Thunbergii 8-12 part, rhizoma sparganic 6-12 part, Rhizoma Pinelliae 6-12 part, Pericarpium Citri Reticulatae 8-20 part.

In order to improve curative effect, can on the basis of above-mentioned prescription, increase following component and content (weight ratio) Radix Angelicae Sinensis 10-20 part, Radix Rehmanniae 10-30 part, Rhizoma Curcumae 8-16 part, Rhizoma Chuanxiong 6-16 part,

The optimal components ratio scope of second kind of prescription is: Radix Astragali 35-60 part, Radix Codonopsis 15-30 part, Radix Salviae Miltiorrhizae 10-20 part, Radix Angelicae Sinensis 10-16 part, Radix Rehmanniae 10-30 part, Sargassum 10-20 part, Thallus Laminariae (Thallus Eckloniae) 10-20 part, Spica Prunellae 10-20 part, Concha Ostreae 20-30 part, Bulbus Fritillariae Thunbergii 8-12 part, Rhizoma Curcumae 8-16 part, rhizoma sparganic 6-12 part, Rhizoma Pinelliae 6-12 part, Rhizoma Chuanxiong 6-16 part, Pericarpium Citri Reticulatae 10-16 part.

In order to treat, can be in above-mentioned three kinds of prescriptions increase following component and content (weight ratio) on any one the basis: Radix Ampelopsis 8-20 part, Flos Chrysanthemi 6-20 part, Flos Eriocauli 6-20 part, Herba Senecionis Scandentis 8-20 part with the obviously hyperthyroidism of the prominent symptom of eye.

In order to treat concurrent cardiopathic hyperthyroidism disease, can on first kind or second kind or the third prescription basis, increase following component and content (weight ratio): Semen Ziziphi Spinosae 10-36 part, Radix Scrophulariae 8-20 part, Rhizoma Acori Graminei 10-25 part, Semen Platycladi 10-30 part.

Above-mentioned prescription all adopts conventional method to prepare the Chinese medicine of various dosage forms, as powder, capsule, honeyed pill, oral liquid, injection etc.

The present invention is on traditional theory of Chinese medical science basis, in conjunction with modern Chinese medicine immunology theory, creatively selects prescription for use, has the endocrine regulation function, strengthens effects such as body immunity, activating QI to eliminate phlegm, the wart that disappears eliminating stagnation.Clinical trial certificate has obvious curative effects to the concurrent thyroid tumor of hyperthyroidism, the concurrent thyroid cyst of hyperthyroidism, goiter etc.

The specific embodiment,

Embodiment sees Table 1.

Prescription with embodiment 1, embodiment 2, embodiment 3 and embodiment 4 respectively is mixed with water preparation (decoction) 150ml, and potion divided and took for three times every day.Carry out clinical experiment 71 examples, carry out clinical observation symptom and sign, basal metabolic rate, B ultrasonic sound, serum FT after 2 months courses of treatment ₄, FT ₃Deng summary, and with background technology two recipe ratios, its curative effect sees Table 2.

Respectively be made into water preparation (decoction) 150ml with prescription shown in embodiment 5, embodiment 6 and the embodiment 7, potion divided and took for three times every day.Clinical experiment 106 examples, summarize 2 months courses of treatment, and its curative effect sees Table 3.

Above-mentioned criterion of therapeutical effect referring to " tcm internal medicine today " (Wang Yongyan, Li Delin the work, Beijing, the People's Health Publisher, 2000 the 1st edition).

Cure: local lump and General Symptoms disappear.

Take a turn for the better: local lump dwindles, and General Symptoms alleviates.

Do not heal: local lump does not have and dwindles, and General Symptoms does not have improvement.

Below lifting several actual medical records is illustrated.

1, Tian Yue, woman, 11 years old, electric three family members of company in east.Suizhong County, Huludao City, Liaoning Province was lived 4 years, and mother suffers from thyromegaly.JIUYUE was gone to a doctor on the 23rd in 2000.Main suit: fear heat, hyperhidrosis, impatient hot-tempered, polyphagia, easily hungry.Have a medical check-up: thyroid nodule II ⁰, hand tremor, 90 times/min of heart rate, blood pressure 95/45mmHg, basal metabolic rate+29%, serum FT ₄27.1, FT ₃9.2poml/L, diagnosis: hyperthyroidism.Take medicine (embodiment 1) 2 months check: thyroid knot and General Symptoms disappear.Serum FT ₄, FT ₃And basal metabolic rate is normal, clinical cure.Follow up a case by regular visits to not recurrence in 3 years.

2, Sheng Yuqiu, the woman, 25 years old, the huge energy in Liaoning company, the office worker goes to a doctor the main suit: suffered from hyperthyroidism and obey thiamazole, irritated drug eruption, leukopenia 3.4 * 10 in 1997 on April 19th, 2000 ⁹/ L, drug withdrawal comes institute, the main suit: fidgety fatigue and weak.Have a medical check-up: goiter diffusivity II ⁰, finger trembles, 80 times/min of heart rate, blood pressure 100/80mmHg, light red tongue, thready pulse, diagnosis: hyperthyroidism and leukopenia.Summed up in 2 months through take medicine (embodiment 2), thyroid anthorisma and General Symptoms disappear, leukocyte 6.0 * 10 ⁹/ L cures.

3, a left side is violent, the man, and 22 years old, the carton factory workman of Jinzhou City, on April 24th, 2000 went to a doctor, the main suit: goiter, half a year, To Be Protected from Heat, hyperhidrosis, vexed, irritability, weak, polyphagia, easy hungry, weight loss 10kg, stool days 3 times.Have a medical check-up: thyroid diffuse type enlargement II ⁰, vascular murmur (+), hands tremor linguae, basal metabolic rate+44%, 100 times/min of heart rate, blood pressure 115/60mmHg, red tongue, rapid pulse, serum FT ₄31.1, FT ₃9.3poml/L.Diagnosis: hyperthyroidism.By taking medicine (implement prescription 3) 2 months, check: enlargement of thyroid diffuse type and General Symptoms disappear, basal metabolic rate and FT ₄, FT ₃All recover normal value, cure.

4, Chen Xiuli, the woman, 28 years old, No. 7, the B building in the garden, Jinzhou City, Liaoning Province.On January 8th, 2000 went to a doctor, and suffered from hyperthyroidism more than 1 year, and clothes antithyroid drug thiamazole goes out the drug eruption drug withdrawal.Main suit: fear heat, hyperhidrosis, fidgety, weak, easy hungry, the menstrual blood volume minimizing in food back.Have a medical check-up: thyromegaly II ⁰, ultrasound diagnosis is nodular type, vascular murmur (+), hands tremor linguae (+), basal metabolic rate+50%, FT ₄31.7poml/L, FT ₃9.7poml/L, 96 times/min of heart rate, blood pressure 110/45mmHg, body of the tongue is loose in vain, thready and rapid pulse.Diagnosis: hyperthyroidism and tuberosity.By taking medicine (implement prescription 4) 2 months, thyroid nodule and General Symptoms disappear, basal metabolic rate, FT ₄, FT ₃And heart rate all recovers normal value, healing.

5, Niu Yulan, woman, 65 years old, hyperthyroidism recurrence.Examine the main suit on April 8th, 2000: hyperhidrosis, vexed, irritability, fatigue and weak, have a medical check-up: thyromegaly II ⁰, hands, tremor linguae, basal metabolic rate+69%, 120 times/min of heart rate, blood pressure 130/70mmHg, electrocardiogram: tachycardia, chamber morning, red tongue, irregularly rapid pulse, serum FT ₄5.6poml/L, FT ₃11.5poml/L.Diagnosis: hyperthyroidism and heart disease.Sum up after 2 months by take medicine (implementing prescription 7), thyromegaly and General Symptoms disappear, serum FT ₄3.9poml/L, FT ₃5.0poml/L, 90 times/min of heart rate, clinical cure.

6, Jia Zhen, the woman, 47 years old, goiter more than 10 year is become thin in recent years, and was weak.Went to a doctor the main suit on October 11st, 2000: To Be Protected from Heat, polyphagia, weak, hyperhidrosis, haves a medical check-up: thyroid nodule enlargement III ⁰, the finger tremble, expophthalmos II ⁰, serum FT ₄6.1, FT ₃11.9poml/L, diagnosis: the hyperthyroidism expophthalmos, take embodiment 6 treatments 2 months, check: the thyroid lump, the basic disappearance, expophthalmos and General Symptoms disappear, serum FT ₄, FT ₃It is normal that value is recovered, and cures.

Table 1

Example formulations

Table 2

Embodiment 1,2,3,4 and ZAOYAO SAN, SHUGAN XIAOYING TANG Comparison of therapeutic

Prescription	Clinical number	Cure		Take a turn for the better		Invalid		Total effective rate
		Cure		Take a turn for the better		Invalid			Number	Account for total %	Number	Account for total %	Number	Account for total %
		The present invention's prescription	????71	??54	??76	???17	??24		Number	Account for total %	Number	Account for total %	Number	Account for total %	??0	????0	??100
ZAOYAO SAN	????36	The present invention's prescription	????71	??54	??76	???17	??24	??16	??44.5	???17	??47.2	??3	????8.3	??91.66	??0	????0	??100
ZAOYAO SAN	????36	SHUGAN XIAOYING TANG	????32	??16	??50	???22	??68.8	??16	??44.5	???17	??47.2	??3	????8.3	??91.66	??3	????9.3	??90.6

Table 3

Embodiment 5,6,7 therapeutic effect

Clinical number	Cure		Take a turn for the better		Invalid		Total effective rate %
	Cure		Take a turn for the better		Invalid			Number	Account for total %	Number	Account for total %	Number	Account for total %
	??106	??85	?80.2	??21	?19.8	?0		Number	Account for total %	Number	Account for total %	Number	Account for total %	???0	??100

Claims

1, a kind of Chinese herbal medicine for the treatment of hyperthyroidism, it comprises following component and content (weight ratio): Radix Astragali 25-80 part, Radix Codonopsis 10-40 part, Radix Salviae Miltiorrhizae 8-20 part, Sargassum 10-20 part, Thallus Laminariae (Thallus Eckloniae) 10-20 part, Spica Prunellae 10-20 part, Concha Ostreae 20-30 part, Bulbus Fritillariae Thunbergii 8-12 part, rhizoma sparganic 6-12 part, Rhizoma Pinelliae 6-12 part, Pericarpium Citri Reticulatae 8-20 part.

2,, it is characterized in that it also comprises Radix Angelicae Sinensis 10-20 part, Radix Rehmanniae 10-30 part, Rhizoma Curcumae 8-16 part, Rhizoma Chuanxiong 6-16 part according to the Chinese herbal medicine of the said treatment hyperthyroidism of claim 1.

3,, it is characterized in that Radix Astragali 35-60 part, Radix Codonopsis 15-30 part, Radix Salviae Miltiorrhizae 10-20 part, Radix Angelicae Sinensis 10-16 part, Radix Rehmanniae 10-30 part, Sargassum 10-20 part, Thallus Laminariae (Thallus Eckloniae) 10-20 part, Spica Prunellae 10-20 part, Concha Ostreae 20-30 part, Bulbus Fritillariae Thunbergii 8-12 part, Rhizoma Curcumae 8-16 part, rhizoma sparganic 6-12 part, Rhizoma Pinelliae 6-12 part, Rhizoma Chuanxiong 6-16 part, Pericarpium Citri Reticulatae 10-16 part according to the Chinese herbal medicine of the said treatment hyperthyroidism of claim 2.

4,, it is characterized in that it also comprises following component and content (weight ratio): Radix Ampelopsis 8-20 part, Flos Chrysanthemi 6-20 part, Flos Eriocauli 6--20 part, Herba Senecionis Scandentis 8-20 part according to the Chinese herbal medicine of claim 1 or 2 or 3 said treatment hyperthyroidisms.

5,, it is characterized in that it also comprises following component and content (weight ratio): Semen Ziziphi Spinosae 10-36 part, Radix Scrophulariae 8-20 part, Rhizoma Acori Graminei 10-25 part, Semen Platycladi 10-30 part according to the Chinese herbal medicine of claim 1 or 2 or 3 said treatment hyperthyroidisms.