CN104587193A - Medicinal liquor for hyperthyroidism and failure of blood to nourish heart and preparation method thereof - Google Patents

Abstract

The invention discloses medicinal liquor for hyperthyroidism and failure of blood to nourish heart. The medicinal liquor is prepared from the following main raw materials in parts by weight: 15-25 parts of pericarpium citri reticulatae, 10-20 parts of fingered citron, 15-30 parts of radix polygonati officinalis, 9-18 parts of rhizoma pinelliae preparata, 15-20 parts of kelp, 9-18 parts of seaweed, 8-16 parts of raw oyster shells, 10-20 parts of wolfberry, 5-8 parts of fungus-infected corn spike, 4-6 parts of Chinese violet, 2-3 parts of potassium iodide, 15-30 parts of rock candy, 9-12 parts of perilla stems, 10-16 parts of fructus aurantii, 6-9 parts of flos caryophylli, 10-25 parts of white paeony root, 8-12 parts of selfheal, 8-12 parts of thunberg fritillary bulb, 9-15 parts of radix scrophulariae and 4-9 parts of airpotato yam rhizome. The medicinal liquor disclosed by the invention has the functions of benefiting qi and activating blood circulation, supporting yang and dredging meridians, soothing liver and regulating qi, and nourishing liver and kidney. Moreover, the medicinal liquor is simple to prepare, easily available in raw materials, suitable for being popularly taken, and great in application prospect.

Description

Hyperthyroidism disease and blood nourish heart medicated wine and method for making

Technical field

The present invention relates to traditional Chinese medicine field, especially relate to a kind of hyperthyroidism disease and blood and to nourish heart medicated wine and method for making.

Background technology

The full name of hyperthyroidism is hyperthyroidism, is due to the too much thyroxin of thyroid synthesis release, causes the hyperfunction and sympathetic activation of organism metabolism, causes cardiopalmus, perspiration, feed and the just secondary disease increasing and lose weight.Most of patients also usually has the symptoms such as expophthalmos, blepharoedema, visual deterioration simultaneously.

Hyperthyroid patient main manifestations is clinically: nervous, tachycardia, To Be Protected from Heat, hyperhidrosis, bulimia, become thin, weight loss, fatigue and weak and emotion are emotional, irascible temperament, insomnia, absent-minded, exophthalmos, hands tremor of the tongue are trembled, goiter or enlargement, women can have menoxenia even amenorrhea, male can have sexual impotence or breast development etc.Thyromegaly is property symmetrically, and the patient also had is asymmetry enlargement, and goiter or enlargement can move up and down along with swallowing, and also some hyperthyroid patient has thyroid nodule.The eye that causes during hyperthyroidism changes, and a class is benign exophthalmos, patient's exophthalmos, eye gaze or present terrified expression in the eyes; Another kind is malignant exophthalmos, can be changed by benign exophthalmos and form, malignant exophthalmos patient Chang You keeps in dark place, shed tears, diplopia, visual deterioration, eye swell and ache, twinge, have foreign body sensation etc., because eyeball height is given prominence to, eyes can not be closed, conjunctiva, cornea expose and cause hyperemia, edema, corneal ulceration etc., even blind.Also the hyperthyroid patient had do not have eye symptom or symptom not obvious.Above-mentioned is all clinical manifestations of typical hyperthyroidism, but not every hyperthyroidism suffers from all clinical symptoms, dissimilar hyperthyroidism, and clinical manifestation is also different.Common complication 1. hyperthyroidism merges gestation: hyperthyroidism mostly occurs in the women at reproduction age, so often run into some hyperthyroidisms clinically to merge pregnant patient, because antithyroid drug has teratogenesis to fetus, so needs and doctor discuss jointly according to the state of an illness, determine staying or giving up of fetus.Graves Disease in Pregnancy patient is the contraindication of radioiodine therapy, the hyperthyroid patient majority continuing gestation is needed to adopt Drug therapy, adopt minimum effective dose as far as possible, try not in treatment to add with thyroxin simultaneously, every 1-3 month needs measure free T4 (FT4), free T3 (FT3) and TSH, instead of total T4 and total T3.Upper limit free T4 being maintained normal value is needed in treatment.2. Thyroid-related Ophthalmopathy: hyperthyroidism majority is that Gravs is sick; that one belongs to organ autoimmune disease; organ autoimmune disease usually can merge other organ autoimmune diseases; hyperthyroid patient usually merges expophthalmos, and expophthalmos is the organ autoimmune disease of eye socket (fatty after comprising extraocular muscles and eyeball).Clinically except Graves patient can show expophthalmos, some other Autoimmune Thyroid Diseases, as chronic lymphocytic thyroiditis also can show expophthalmos, so we are called Thyroid-related Ophthalmopathy.

The method of existing Chinese traditional treatment hyperthyroidism is more, publication number CN 103211977 A (application number 201310171399.5) patent document discloses a kind of Chinese medicine preparation for the treatment of hyperthyroidism disease, and this Chinese medicine preparation is made up of the Chinese medicine of following weight portion: Herba Abri 5-40 part, Fructus Akebiae 3-15 part, Herba Hemipiliae Flabellatae 1-20 part, Selenitum 3-25 part, Radix Rehmanniae 10-15 part, Radix Asparagi 7-9 part, Radix Ophiopogonis Dracaenoidis 6-28 part, Cortex Albiziae 7-10 part, Cortex Sorbariae Arboreae 4-17 part, Cornu procaprae gutturosae 1-30 part, Concha Ostreae 8-10 part, Rhizoma Dioscoreae Bulbiferae 6-15 part, Semen clausenae lansii 2-10 part.Publication number CN 103202965 A (application number 201310155160.9) patent document discloses a kind of medicine for the treatment of hyperthyroidism and preparation method thereof, it is made up of the crude drug in following weight range: Flos Pruni mume 10-20 gram, Rhizoma Dioscoreae Bulbiferae 8-12 gram, Dens Draconis 8-12 gram, Semen Lablab Album 10-20 gram, Radix Ranunculi Ternati 8-12 gram, Fructus Citri Sarcodactylis 8-12 gram, Pumex 8-15 gram, Pseudobulbus cremastrae seu pleiones 8-12 gram, Thallus Porphyrae 8-15 gram, Radix Stellariae 8-15 gram, Rhizoma Anemarrhenae 8-15 gram, Fructus Mume 8-15 gram, Cortex Albiziae 8-15 gram, Thallus Laminariae (Thallus Eckloniae) 8-15 gram, Semen Ziziphi Spinosae 8-15 gram, Caulis Bambusae In Taenia 8-15 gram, Radix Semiaquilegiae 10-15 gram, Carapax et Plastrum Testudinis 8-15 gram, Herba Dendrobii 10-20 gram.Publication number CN 103041299 A(application number 201210554037.X) patent document discloses a kind of Chinese medicine for the treatment of hyperthyroidism, be made up of the component of following weight, the Radix Angelicae Dahuricae 10 grams, Radix Arnebiae (Radix Lithospermi) 10 grams, Olibanum 10 grams, Borneolum Syntheticum 10 grams, Oleum Verniciae fordii 10 grams, Radix Saposhnikoviae 10 grams, prepared RHIZOMA SPARGANII with vine-gar 10 grams, Semen Citri Reticulatae 10 grams, Radix Bupleuri 10 grams, Radix Curcumae 10 grams, Radix Codonopsis 10 grams, Radix Salviae Miltiorrhizae 10 grams, 10 grams, the Radix Rehmanniae, 10 grams, Radix Glycyrrhizae, Rhizoma Chuanxiong 10 grams, Radix Ophiopogonis 10 grams, the Rhizoma Anemarrhenae 10 grams, Radix Scrophulariae 10 grams, Radix Polygoni Multiflori 10 grams, Cortex Phellodendri 10 grams, Bulbus Fritillariae Uninbracteatae 10 grams.

The prior art comprising above-mentioned patent documentation achieves certain achievement in treatment hyperthyroidism, and the method for current clinical treatment hyperthyroidism disease mainly contains Drug therapy, radiotherapy and operative treatment.Though Drug therapy can alleviate disease to a certain extent, cure the symptoms, not the disease, radiotherapy has carcinogenesis, and operative treatment easily causes sequela.Chinese medicine also exists the difficult problems such as the course of disease is long, refractory more, easily recurs, uncertain therapeutic efficacy is cut.

Summary of the invention

For the deficiency of prior art treatment hyperthyroidism, an object of the present invention is to provide a kind of hyperthyroidism disease and blood to nourish heart medicated wine, and select multiple Chinese herbal medicine, dialectical compatibility, has benefiting QI for activating blood circulation, supporing yangly promotes blood circulation, depressed liver-energy dispersing and QI regulating, the effect of nourishing the liver and kidney.Another object is just to provide above-mentioned hyperthyroidism disease and blood and nourishes heart the preparation method of medicated wine.

Above-mentioned purpose of the present invention is achieved through the following technical solutions:

Hyperthyroidism disease and blood nourish heart medicated wine, take off the primary raw material stating weight proportion and are prepared from: Pericarpium Citri Reticulatae 15-25 part; Fructus Citri Sarcodactylis 10-20 part; Rhizoma Polygonati Odorati 15-30 part; Rhizoma Pinelliae 9-18 part; Thallus Laminariae (Thallus Eckloniae) 15-20 part; Sargassum 9-18 part; Concha Ostreae 8-16 part; Fructus Lycii 10-20 part; Ustilago crameri Koern. 5-8 part; Herba Violae 4-6 part; Potassium iodide 2-3 part; Crystal sugar 15-30 part; Caulis Perillae 9-12 part; Fructus Aurantii 10-16 part; Flos Caryophylli 6-9 part; Radix Paeoniae Alba 10-25 part; Spica Prunellae 8-12 part; Bulbus Fritillariae Thunbergii 8-12 part; Radix Scrophulariae 9-15 part; Rhizoma Dioscoreae Bulbiferae 4-9 part.

Hyperthyroidism disease and blood nourish heart medicated wine, and preferred scheme is, takes off the primary raw material stating weight proportion and is prepared from: Pericarpium Citri Reticulatae 18-22 part; Fructus Citri Sarcodactylis 13-17 part; Rhizoma Polygonati Odorati 20-25 part; Rhizoma Pinelliae 12-15 part; Thallus Laminariae (Thallus Eckloniae) 16-19 part; Sargassum 12-15 part; Concha Ostreae 11-13 part; Fructus Lycii 13-17 part; Ustilago crameri Koern. 6-7 part; Herba Violae 4.5-5.5 part; Potassium iodide 2.3-2.7 part; Crystal sugar 20-25 part; Caulis Perillae 10-11 part; Fructus Aurantii 12-14 part; Flos Caryophylli 7-8 part; Radix Paeoniae Alba 15-20 part; Spica Prunellae 9-11 part; Bulbus Fritillariae Thunbergii 9-11 part; Radix Scrophulariae 11-13 part; Rhizoma Dioscoreae Bulbiferae 5-8 part.

Hyperthyroidism disease and blood nourish heart medicated wine, and the scheme be more preferably is, takes off the primary raw material stating weight proportion and is prepared from: Pericarpium Citri Reticulatae 20 parts; Fructus Citri Sarcodactylis 15 parts; Rhizoma Polygonati Odorati 22 parts; Rhizoma Pinelliae 13 parts; Thallus Laminariae (Thallus Eckloniae) 17 parts; Sargassum 13 parts; Concha Ostreae 12 parts; Fructus Lycii 15 parts; Ustilago crameri Koern. 6.5 parts; Herba Violae 5 parts; Potassium iodide 2.5 parts; 22 parts, crystal sugar; Caulis Perillae 10.5 parts; Fructus Aurantii 13 parts; Flos Caryophylli 7.5 parts; The Radix Paeoniae Alba 18 parts; Spica Prunellae 10 parts; Bulbus Fritillariae Thunbergii 10 parts; Radix Scrophulariae 12 parts; Rhizoma Dioscoreae Bulbiferae 7 parts.

Above-mentioned hyperthyroidism disease and blood nourish heart the preparation method of medicated wine, and step is as follows:

(1) Concha Ostreae and Bulbus Fritillariae Thunbergii are smashed, be placed in refractory container, intense fire heating 20-30 minute, takes out, cools;

(2) be placed in parch container by Caulis Perillae, the Radix Paeoniae Alba, Radix Scrophulariae and Rhizoma Dioscoreae Bulbiferae, moderate heat fries 20-30 minute, cools;

(3) Pericarpium Citri Reticulatae, Fructus Citri Sarcodactylis, Rhizoma Polygonati Odorati, Rhizoma Pinelliae, Thallus Laminariae (Thallus Eckloniae), Sargassum, Fructus Lycii, Herba Violae, Fructus Aurantii, Flos Caryophylli and Spica Prunellae are put into airtight non iron container, add step (1)-(2) gains and Chinese liquor, every day shakes, 20-30 days is soaked in sealing, filter and remove residue, gets upper strata clarification medicated liquor;

(4) by crystal sugar porphyrize repeatedly, mix homogeneously with Ustilago crameri Koern. and potassium iodide;

(5) step (4) gained powder is joined in step (3) gained filtrate, leave standstill 5-9 hour, get supernatant.

Above-mentioned hyperthyroidism disease and blood nourish heart the preparation method of medicated wine, and preferred scheme is: step (1) is intense fire heating 23-27 minute preferably, is more preferably intense fire and heats 25 minutes.

Above-mentioned hyperthyroidism disease and blood nourish heart the preparation method of medicated wine, and preferred scheme is: step (1) preferably moderate heat fries 23-27 minute, is more preferably moderate heat and fries 25 minutes.

Above-mentioned hyperthyroidism disease and blood nourish heart the preparation method of medicated wine, and preferred scheme is: the concentration that step (3) preferably adds Chinese liquor is 50o-60 °, and being more preferably the concentration adding Chinese liquor is 55o.

Above-mentioned hyperthyroidism disease and blood nourish heart the preparation method of medicated wine, and preferred scheme is: the Chinese liquor of the preferred Sorghum vulgare Pers. brew of step (3), consumption be the 10-15 of total quality of medicinal material doubly, be more preferably the Chinese liquor of Sorghum vulgare Pers. brew, consumption is 12 times of total quality of medicinal material.

Above-mentioned hyperthyroidism disease and blood nourish heart the preparation method of medicated wine, and preferred scheme is: step (3) preferably sealing soaks 23-27 days, is more preferably sealing immersion 25 days.

Above-mentioned hyperthyroidism disease and blood nourish heart the preparation method of medicated wine, and preferred scheme is: step (5) preferably leaves standstill 6-8 hour, is more preferably standing 7 hours.

using method: drinking 40-60ml at every turn, drink 2 every day, 15 days is a course for the treatment of.

Beneficial effect of the present invention is embodied in:

1, the present invention is having remarkable result on Treatment of Hyperthyroidism, to human organ particularly to liver avirulence, has effectively evaded in the past larger side effect, has had breakthrough meaning to the treatment of hyperthyroidism.

2, the present invention selects multiple Chinese herbal medicine, and dialectical compatibility, has benefiting QI for activating blood circulation, supporing yangly promotes blood circulation, depressed liver-energy dispersing and QI regulating, the effect of nourishing the liver and kidney.

3, drug effect of the present invention is comprehensive, can conditions of patients be made rapidly to take a turn for the better, fundamentally alleviate disease.

4, Chinese medicine composition preparation of the present invention is simple, and raw material is easy to get, and is suitable for popular use, has good application prospect.

Detailed description of the invention

Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.

embodiment 1hyperthyroidism disease and blood nourish heart medicated wine, take off to state primary raw material and be prepared from (getting 60g for every part): Pericarpium Citri Reticulatae 15 parts; Fructus Citri Sarcodactylis 10 parts; Rhizoma Polygonati Odorati 15 parts; Rhizoma Pinelliae 9 parts; Thallus Laminariae (Thallus Eckloniae) 15 parts; Sargassum 9 parts; Concha Ostreae 8 parts; Fructus Lycii 10 parts; Ustilago crameri Koern. 5 parts; Herba Violae 4 parts; Potassium iodide 2 parts; 15 parts, crystal sugar; Caulis Perillae 9 parts; Fructus Aurantii 10 parts; Flos Caryophylli 6 parts; The Radix Paeoniae Alba 10 parts; Spica Prunellae 8 parts; Bulbus Fritillariae Thunbergii 8 parts; Radix Scrophulariae 9 parts; Rhizoma Dioscoreae Bulbiferae 4 parts.

Hyperthyroidism disease and the blood medicated wine preparation process that nourishes heart is as follows:

(1) Concha Ostreae and Bulbus Fritillariae Thunbergii are smashed, be placed in refractory container, intense fire heats 20 minutes, takes out, cools;

(2) be placed in parch container by Caulis Perillae, the Radix Paeoniae Alba, Radix Scrophulariae and Rhizoma Dioscoreae Bulbiferae, moderate heat fries 20 minutes, cools;

(3) Pericarpium Citri Reticulatae, Fructus Citri Sarcodactylis, Rhizoma Polygonati Odorati, Rhizoma Pinelliae, Thallus Laminariae (Thallus Eckloniae), Sargassum, Fructus Lycii, Herba Violae, Fructus Aurantii, Flos Caryophylli and Spica Prunellae are put into airtight non iron container, add step (1)-(2) gains and Chinese liquor, every day shakes, sealing immersion 20 days, filter and remove residue, gets upper strata clarification medicated liquor;

(4) by crystal sugar porphyrize repeatedly, mix homogeneously with Ustilago crameri Koern. and potassium iodide;

(5) step (4) gained powder is joined in step (3) gained filtrate, leave standstill 5 hours, get supernatant.

Using method: at every turn drink 40-60ml, drinks 2 every day, within 15 days, is a course for the treatment of.

embodiment 2hyperthyroidism disease and blood nourish heart medicated wine, take off to state primary raw material and be prepared from (getting 20g for every part): Pericarpium Citri Reticulatae 25 parts; Fructus Citri Sarcodactylis 20 parts; Rhizoma Polygonati Odorati 30 parts; Rhizoma Pinelliae 18 parts; Thallus Laminariae (Thallus Eckloniae) 20 parts; Sargassum 18 parts; Concha Ostreae 16 parts; Fructus Lycii 20 parts; Ustilago crameri Koern. 8 parts; Herba Violae 6 parts; Potassium iodide 3 parts; 30 parts, crystal sugar; Caulis Perillae 12 parts; Fructus Aurantii 16 parts; Flos Caryophylli 9 parts; The Radix Paeoniae Alba 25 parts; Spica Prunellae 12 parts; Bulbus Fritillariae Thunbergii 12 parts; Radix Scrophulariae 15 parts; Rhizoma Dioscoreae Bulbiferae 9 parts.

Hyperthyroidism disease and the blood medicated wine preparation process that nourishes heart is as follows:

(1) Concha Ostreae and Bulbus Fritillariae Thunbergii are smashed, be placed in refractory container, intense fire heats 30 minutes, takes out, cools;

(2) be placed in parch container by Caulis Perillae, the Radix Paeoniae Alba, Radix Scrophulariae and Rhizoma Dioscoreae Bulbiferae, moderate heat fries 30 minutes, cools;

(3) Pericarpium Citri Reticulatae, Fructus Citri Sarcodactylis, Rhizoma Polygonati Odorati, Rhizoma Pinelliae, Thallus Laminariae (Thallus Eckloniae), Sargassum, Fructus Lycii, Herba Violae, Fructus Aurantii, Flos Caryophylli and Spica Prunellae are put into airtight non iron container, add step (1)-(2) gains and Chinese liquor, every day shakes, sealing immersion 30 days, filter and remove residue, gets upper strata clarification medicated liquor;

(4) by crystal sugar porphyrize repeatedly, mix homogeneously with Ustilago crameri Koern. and potassium iodide;

(5) step (4) gained powder is joined in step (3) gained filtrate, leave standstill 9 hours, get supernatant.

Using method: at every turn drink 40-60ml, drinks 2 every day, within 15 days, is a course for the treatment of.

model case oneyan XX, female, 44 years old, peasant, Tai'an, Shandong Province from Dongping County.Before 6 years without occurring under obvious inducement nervous becoming thin, weak, the cardio palmus shape of To Be Protected from Heat hyperhidrosis, limbs, go to hospital to be diagnosed as hyperthyroidism on inspection, oral thiamazole, after about one year, symptom is obviously improved, and alleviates dose and continues to take 1 year, look into T3, T4, Non Apparent Abnormality.Occurred before 1 year that nervous, times of defecation increases, check T3, T4, prompting hyperthyroidism recurrence, so continue oral methimazole treatment, takes malaise symptoms so far and does not still improve.

Taking gained hyperthyroidism disease of the present invention and blood nourishes heart after 2 courses for the treatment of of medicated wine (embodiment 2), nervously to become thin, To Be Protected from Heat hyperhidrosis, limbs are weak, cardio palmus shape obviously alleviates.After continuing to take 2 courses for the treatment of, various malaise symptoms disappears substantially, and check finds that T3, T4 recover normal level.Visit and learn and fully recover.

embodiment 3hyperthyroidism disease and blood nourish heart medicated wine, take off to state primary raw material and be prepared from (getting 50g for every part): Pericarpium Citri Reticulatae 18 parts; Fructus Citri Sarcodactylis 13 parts; Rhizoma Polygonati Odorati 20 parts; Rhizoma Pinelliae 12 parts; Thallus Laminariae (Thallus Eckloniae) 16 parts; Sargassum 12 parts; Concha Ostreae 11 parts; Fructus Lycii 13 parts; Ustilago crameri Koern. 6 parts; Herba Violae 4.5 parts; Potassium iodide 2.3 parts; 20 parts, crystal sugar; Caulis Perillae 10 parts; Fructus Aurantii 12 parts; Flos Caryophylli 7 parts; The Radix Paeoniae Alba 15 parts; Spica Prunellae 9 parts; Bulbus Fritillariae Thunbergii 9 parts; Radix Scrophulariae 11 parts; Rhizoma Dioscoreae Bulbiferae 5 parts.

Hyperthyroidism disease and the blood medicated wine preparation process that nourishes heart is as follows:

(1) Concha Ostreae and Bulbus Fritillariae Thunbergii are smashed, be placed in refractory container, intense fire heats 23 minutes, takes out, cools;

(2) be placed in parch container by Caulis Perillae, the Radix Paeoniae Alba, Radix Scrophulariae and Rhizoma Dioscoreae Bulbiferae, moderate heat fries 23 minutes, cools;

(3) Pericarpium Citri Reticulatae, Fructus Citri Sarcodactylis, Rhizoma Polygonati Odorati, Rhizoma Pinelliae, Thallus Laminariae (Thallus Eckloniae), Sargassum, Fructus Lycii, Herba Violae, Fructus Aurantii, Flos Caryophylli and Spica Prunellae are put into airtight non iron container, add step (1)-(2) gains and Chinese liquor, every day shakes, sealing immersion 23 days, filter and remove residue, gets upper strata clarification medicated liquor;

(4) by crystal sugar porphyrize repeatedly, mix homogeneously with Ustilago crameri Koern. and potassium iodide;

(5) step (4) gained powder is joined in step (3) gained filtrate, leave standstill 6 hours, get supernatant.

Using method: at every turn drink 40-60ml, drinks 2 every day, within 15 days, is a course for the treatment of.

embodiment 4hyperthyroidism disease and blood nourish heart medicated wine, take off to state primary raw material and be prepared from (getting 40g for every part): Pericarpium Citri Reticulatae 22 parts; Fructus Citri Sarcodactylis 17 parts; Rhizoma Polygonati Odorati 25 parts; Rhizoma Pinelliae 15 parts; Thallus Laminariae (Thallus Eckloniae) 19 parts; Sargassum 15 parts; Concha Ostreae 13 parts; Fructus Lycii 17 parts; Ustilago crameri Koern. 7 parts; Herba Violae 5.5 parts; Potassium iodide 2.7 parts; 25 parts, crystal sugar; Caulis Perillae 11 parts; Fructus Aurantii 14 parts; Flos Caryophylli 8 parts; The Radix Paeoniae Alba 20 parts; Spica Prunellae 11 parts; Bulbus Fritillariae Thunbergii 11 parts; Radix Scrophulariae 13 parts; Rhizoma Dioscoreae Bulbiferae 8 parts.

Hyperthyroidism disease and the blood medicated wine preparation process that nourishes heart is as follows:

(1) Concha Ostreae and Bulbus Fritillariae Thunbergii are smashed, be placed in refractory container, intense fire heats 27 minutes, takes out, cools;

(2) be placed in parch container by Caulis Perillae, the Radix Paeoniae Alba, Radix Scrophulariae and Rhizoma Dioscoreae Bulbiferae, moderate heat fries 27 minutes, cools;

(3) Pericarpium Citri Reticulatae, Fructus Citri Sarcodactylis, Rhizoma Polygonati Odorati, Rhizoma Pinelliae, Thallus Laminariae (Thallus Eckloniae), Sargassum, Fructus Lycii, Herba Violae, Fructus Aurantii, Flos Caryophylli and Spica Prunellae are put into airtight non iron container, add step (1)-(2) gains and Chinese liquor, every day shakes, sealing immersion 27 days, filter and remove residue, gets upper strata clarification medicated liquor;

(4) by crystal sugar porphyrize repeatedly, mix homogeneously with Ustilago crameri Koern. and potassium iodide;

(5) step (4) gained powder is joined in step (3) gained filtrate, leave standstill 8 hours, get supernatant.

Using method: at every turn drink 40-60ml, drinks 2 every day, within 15 days, is a course for the treatment of.

model case twochu XX, man, 35 years old, people from Lixia District, Jinan City, Shandong Province.Without there is poor appetite, nausea and vomiting under obvious inducement, suffer from diarrhoea, become thin, cardiopalmus, the symptom such as hyperhidrosis.In local hospital inspection, be diagnosed as acute viral hepatitis, implement corresponding treatment 2 weeks invalid.So transfer from one hospital to another, have a medical check-up: double eyeball is slightly prominent, upper eyelid falls (+) late, and eyes cohesion is poor, thyroid I degree of enlargement.Lab testing: leukocyte 6.5 × 10 ⁹/ L, hemoglobin 131g/L, urobilinogen (+), urine bilirubin (-), trilute (T3) 26nmol/L, thyroxine (T4) 217nmol/L, thyrotropin (TSH) 2mU/L.Be diagnosed as hyperthyroidism (abbreviation hyperthyroidism).

Taking gained hyperthyroidism disease of the present invention and blood nourishes heart after 2 courses for the treatment of of medicated wine (embodiment 4), poor appetite, nausea and vomiting, suffer from diarrhoea, become thin, cardiopalmus, the symptom such as hyperhidrosis obviously alleviate.After continuing to take 2 courses for the treatment of, gastrointestinal symptom is alleviated, liver function indices, and T3, T4, TSH etc. are all close to normal.Have no adverse reaction during medication, do not use other drug auxiliary treatment.

embodiment 5hyperthyroidism disease and blood nourish heart medicated wine, take off to state primary raw material and be prepared from (getting 30g for every part): Pericarpium Citri Reticulatae 20 parts; Fructus Citri Sarcodactylis 15 parts; Rhizoma Polygonati Odorati 22 parts; Rhizoma Pinelliae 13 parts; Thallus Laminariae (Thallus Eckloniae) 17 parts; Sargassum 13 parts; Concha Ostreae 12 parts; Fructus Lycii 15 parts; Ustilago crameri Koern. 6.5 parts; Herba Violae 5 parts; Potassium iodide 2.5 parts; 22 parts, crystal sugar; Caulis Perillae 10.5 parts; Fructus Aurantii 13 parts; Flos Caryophylli 7.5 parts; The Radix Paeoniae Alba 18 parts; Spica Prunellae 10 parts; Bulbus Fritillariae Thunbergii 10 parts; Radix Scrophulariae 12 parts; Rhizoma Dioscoreae Bulbiferae 7 parts.

Hyperthyroidism disease and the blood medicated wine preparation process that nourishes heart is as follows:

(1) Concha Ostreae and Bulbus Fritillariae Thunbergii are smashed, be placed in refractory container, intense fire heats 25 minutes, takes out, cools;

(2) be placed in parch container by Caulis Perillae, the Radix Paeoniae Alba, Radix Scrophulariae and Rhizoma Dioscoreae Bulbiferae, moderate heat fries 25 minutes, cools;

(3) Pericarpium Citri Reticulatae, Fructus Citri Sarcodactylis, Rhizoma Polygonati Odorati, Rhizoma Pinelliae, Thallus Laminariae (Thallus Eckloniae), Sargassum, Fructus Lycii, Herba Violae, Fructus Aurantii, Flos Caryophylli and Spica Prunellae are put into airtight non iron container, add step (1)-(2) gains and Chinese liquor, every day shakes, sealing immersion 25 days, filter and remove residue, gets upper strata clarification medicated liquor;

(4) by crystal sugar porphyrize repeatedly, mix homogeneously with Ustilago crameri Koern. and potassium iodide;

(5) step (4) gained powder is joined in step (3) gained filtrate, leave standstill 7 hours, get supernatant.

Using method: at every turn drink 40-60ml, drinks 2 every day, within 15 days, is a course for the treatment of.

The pharmacological effect of each raw material is respectively:

Pericarpium Citri Reticulatae: bitter in the mouth, pungent, warm in nature.Return lung, spleen channel.Another name Pericarpium Citri tangerinae, expensive old, Folium Styracis Suberifoliae etc.For the dry mature skin of rutaceae orange and variety thereof.There is regulating qi-flowing for strengthening spleen, effect of drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.

Fructus Citri Sarcodactylis: acrid in the mouth, hardship, acid, warm in nature.Return liver, spleen, lung meridian.For the dry fruit of rutaceae Fructus Citri Sarcodactylis.There is liver-smoothing, qi-regulating, and effect of stomach and alleviating pain.For stagnation of liver-QI and stomach-QI. distending pain in the chest and hypochondrium, gastral cavilty feeling of fullness, lack of appetite is vomitted.

Rhizoma Polygonati Odorati: sweet in the mouth, cold nature.Attach to the lung and stomach meridians.For the dry rhizome of liliaceous plant Rhizoma Polygonati Odorati.There is nourishing YIN to relieve dryness, effect of promoting the production of body fluid to quench thirst.For lung stomach-Yin wound, cough caused by dryness-heat, swallow in thirsty, interior-heat is quenched one's thirst.

Rhizoma Pinelliae: acrid in the mouth, warm in nature.Return spleen, stomach warp.For Rhizoma Pinelliae and Alumen boil the Preparation process product of rear drying altogether, and Rhizoma Pinelliae is the dry tuber of the aroid Rhizoma Pinelliae.There is drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, effect of dissolving lump and resolving mass.For damp-phlegm cold drink, cough with asthma abundant expectoration, chest and diaphragm distension, syncope due to accumulation of phlegm is had a headache, dizzy sleeplessness, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, and vomiting regurgitation, thymus painful abdominal mass is vexed, globus hystericus.

Thallus Laminariae (Thallus Eckloniae): salty in the mouth, cold in nature.Return liver, stomach, kidney channel.For the dry thallus of Laminariaceae plant Thallus Laminariae (Thallus Eckloniae) or Alariaceae plant Thallus Laminariae (Thallus Eckloniae).There is hard masses softening and resolving, expectorant, effect of diuretic.For wart cancer, scrofula, painful and swollen testis, phlegm retention edema.

Sargassum: bitter in the mouth, salty, cold in nature.Return liver, stomach, kidney channel.For the dry frond of Sargassaceae plant Sargassum or Sargassum fusiforme (Harv.) Setch.There is hard masses softening and resolving, expectorant, diuretic, effect of anticoagulant and hemostasis.For goiter, scrofula, painful and swollen testis, phlegm retention edema.

Concha Ostreae: salty in the mouth, cold nature.Return liver, gallbladder, kidney channel.For the shell of the long Concha Ostreae of Ostreidae animal, Dalian Bay Concha Ostreae or Crassostrea rivularis.There is tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving, restrain astringent or styptic treatment for spontaneous sweating effect.For insomnia of palpitating with fear, vertigo and tinnitus, scrofula sucutaneous nodule ， mass in the abdomen mass in the abdomen, spontaneous sweating, seminal emission metrorrhagia and leukorrhagia, stomachache acid regurgitation.

Fructus Lycii: sweet in the mouth, property is put down.Return liver, kidney channel.For the dry mature fruit of plant of Solanaceae lycium barbarum.There is nourishing the liver and kidney, effect of replenishing vital essence to improve eyesight.For asthenia damage of essence, doctor's knee joint soreness, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, and blurred vision is failed to understand.

Ustilago crameri Koern.: lightly seasoned, micro-hardship, warm in nature.Return spleen, stomach warp.For Mycophyta Basidiomycetes Ustilaginaceae Ustilago crameri Koern., be used as medicine with teleutospore powder, multiparasitization is on foxtail millet fringe.There is sharp small intestinal, except effect of stuffy sensation with restlessness.For dysuria, the intestines and stomach does not relax, dyspepsia, in the heart stuffy sensation with restlessness.

Herba Violae: bitter in the mouth, pungent, cold in nature.GUIXIN, Liver Channel.For the dry herb of Violaceae Chinese violet.There is heat-clearing and toxic substances removing, effect of removing heat from blood detumescence.For furuncle swelling toxin, cellulitis carbuncle on the back, erysipelas, venom.

Potassium iodide: be colourless crystallization or white crystalline powder; Odorless, salty in the mouth, band are bitter; Micro-have draw moist.Pharmaceutically be used as expectorant, diuretic, goiter control and hyperthyroidism Preoperative medication thing, chronic obstructive pulmonary disease, erythematous skin is sick, sporotrichosis cutis etc.

Crystal sugar: the crystallization reproduced goods being Saccharum Sinensis Roxb., the crystal sugar adularescent of Nature creating, micro-Huang, light grey isochrome, market also has add all kinds of colored crystal sugar of food coloring in addition, such as green, blue, orange, micro-multiple color such as red, dark red.Because its crystallization is as ice-like, therefore named crystal sugar, crystal sugar quality is pure, not perishable, except can making confection and eating, also can be used for gourmet food sweeting agent, and prepare medicines dipping drinks and nourishing adjuvant drug etc.Sweet in the mouth, property is put down, nontoxic.Return lung, spleen channel.There is YIN nourishing and the production of body fluid promoting, nourishing the lung to arrest cough, supplement blood glucose, effect of diuresis removing toxic substances.For xeropulmonary cough, dry cough without phlegm, cough with blood-flecked phlegm, the deficiency of the lung, the cough with asthma caused by wind and cold fatigue, infantile malaria, fasting dysentery, aphtha, acute toothache.

Caulis Perillae: acrid in the mouth, warm in nature.Return lung, spleen channel.For the dry stem of labiate Folium Perillae.There is regulating the flow of QI to ease the stomach, pain relieving, antiabortive effect.Vexed for chest and diaphragm painful abdominal mass, gastralgia, belch is vomitted, frequent fetal movement.

Fructus Aurantii: bitter in the mouth, pungent, sour, warm in nature.Return spleen, stomach warp.For the dry immature fruit of rutaceae Citrus aurantium Linn. and variety thereof.There is regulating the flow of QI to ease the stomach, effect of the stagnant relieving distension of row.For the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention, gastroptosis, proctoptosis, uterine prolapse.

Flos Caryophylli: property is pungent, taste temperature.Return lung, spleen, stomach, kidney four warp.For alabastrum and the fruit of Myrtaceae aiphyllium plant.Alabastrum is containing volatile oil and Oleum Caryophylli, main containing eugenol, acetyleugenol, B-caryophyllene in oil, and methyl-n-amyl ketone, methyl salicylate, Humuleno, benzaldehyde, benzylalcohol, 3-Methoxybenzaldehyde, benzyl acetate, chavicol, a-ylangene etc.Triterpenoid is also contained as oleanolic acid, flavone and chromone class rhamnetin, kaempferol, eugenin, eugenitin, isoeugenitin and demethylation compound isoeugenitol thereof in spending.There is effect of warming middle-JIAO, warming the kidney, sending down the abnormal ascending QI.For singultus, vomiting, regurgitation, dysentery, trusted subordinate's cold type of pain, mass beside the umbilicus, hernia, ringworm.

The Radix Paeoniae Alba: bitter in the mouth, acid, cold in nature.Return liver, spleen channel.For the dry root of ranunculaceae plant Radix Paeoniae.There is suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, effect of astringing YIN to stop sweating.Dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.

Spica Prunellae: acrid in the mouth, hardship, cold in nature.Return liver, gallbladder meridian.For the dry fruit ear of labiate Spica Prunellae.Have and relieve inflammation or internal heat, improving eyesight, eliminating stagnation, effect of detumescence.For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, goiter, and acute mastitis swells and ache; Thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension.

Bulbus Fritillariae Thunbergii: bitter in the mouth, cold in nature.Return lung, heart channel.Another name: Bulbus Fritillariae Thunbergii, resemble shellfish, Bulbus Fritillariae Thunbergii, Bulbus Fritillariae Thunbergii.For the bulb of liliaceous plant Bulbus Fritillariae Thunbergii.Containing peimine, peiminine, peimine glycosides, different peimine, Bulbus Fritillariae Uninbracteatae Buddhist nun fourth alkali, different Bulbus Fritillariae Uninbracteatae Buddhist nun fourth alkali, Bulbus Fritillariae Uninbracteatae sterin, choline etc.There is removing heat-phlegm, sending down the abnormal ascending QI cough-relieving, effect of mass dissipating and swelling eliminating.For wind heat or phlegm-heat cough, lung abscess vomiting pus, scrofula goiter, sore and toxic.

Radix Scrophulariae: sweet in the mouth, hardship, salty, cold nature.Return lung, stomach, kidney channel.For the dry root of goatweed Radix Scrophulariae.There is removing heat from blood YIN nourishing, effect of eliminating fire and detoxication.For consumption of YIN caused by febrile disease, crimson tongue excessive thirst, maculae caused by violent heat pathogen, constipation is hindered in Tianjin, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, and scrofula is sick, diphtheria, carbuncle sore tumefacting virus.

Rhizoma Dioscoreae Bulbiferae: bitter in the mouth, pungent, cool in nature.Return few cloudy, the meridian of Foot-JUE YIN of hands.For the tuber of Dioscoreaceae plant Dioscorea bulbifera L..Rhizoma Dioscoreae Bulbiferae element E acetas is shown containing Rhizoma Dioscoreae Bulbiferae element A-H, 8-.Diosgenin, D-Sorbitol, 2,4,6,7-tetrahydroxy-9-10-dihydro is luxuriant and rich with fragrance, and 2,4,5,6-tetrahydroxy is luxuriant and rich with fragrance, dihydro dioscorine, sucrose, reducing sugar, starch, Saponin, tannin etc.There is removing toxic substances and promoting subsidence of swelling, dissipating phlegm and resolving masses, effect of cooling blood for hemostasis.For thyromegaly, tuberculous lymphadenitis, laryngopharynx swelling and pain, spits blood, spitting of blood, pertussis, cancerous protuberance; Furuncle is controlled in external.

test example: in order to verify that gained hyperthyroidism disease of the present invention and blood nourish heart the curative effect of medicated wine (embodiment 5), we have done contrast test in August ,-2011 in February, 2009.

General data: screen 200 routine hyperthyroid patients in Duo Suo hospital, man 111 example, female 89 example; Minimal ages 21 years old, max age 63 years old, 46.8 years old mean age; 21-40 year 77 people, 41-63 year 123 people.Be divided into experimental group and matched group Liang Ge group (wherein, experimental group 150 people, matched group 50 people) at random.Two groups are compared there was no significant difference (P > 0.05), have comparability in sex, age, the course of disease, state of an illness scoring etc.

Diagnostic criteria: 1. weak, the cardiopalmus of being irritable and irascible, To Be Protected from Heat hyperhidrosis, limbs, receive high easy famine, extremity tremble, ophthalmic bloated, times of defecation are many, menoxenia etc., have wherein more than 6; 2. exophthalmos, widening of palpebral fissure, thyromegaly, trembling of limbs, lose weight, tachycardia, systolic pressure increase, pulse pressure difference increase etc., have wherein more than 4; 3. lab testing: serum T 3, T4 exceed normal value (total T3:1.34-2.73 nmol/L, total T4:78.4-157.4 nmol/L; FT3:3.67-10.43 Pmol/L, FT:4 7.5-21.1 Pmol/L), thyrotropin is lower than normal value (TSH: 0.34-5.60 mIU/L), and iodine uptake rate increases, peak reach person.

Usage and dosage: two groups of patients unify dietary standards.Experimental group is taken gained hyperthyroidism disease of the present invention and blood and to be nourished heart medicated wine, each 40-60ml, every day 2 times, 15 days courses for the treatment of.Matched group: adopt other treatment mode (as thiamazole, methylthiouracil etc.), wherein thiamazole: adult's starting dose is generally 30mg(6 sheet on the one), several oral, decrement gradually after Morbidity control, every day, maintenance dose needed between 5-15mg(1-3 sheet by the state of an illness); When children's starts dosage be every day by body weight 0.4mg/kg, several oral.Methylthiouracil: adult's starting dose is generally 300mg(3 sheet every day), depending on state of an illness weight between 150-400mg(1 sheet half-4), several oral, decrement gradually after Morbidity control, maintenance dose 50-150mg(every day half-1 slice half); Children's's starting dose presses body weight 4mg/kg every day, and several oral, maintenance dose is cut down according to the circumstance.

Criterion of therapeutical effect: recovery from illness: clinical symptom disappearance, sign disappears substantially, and lab testing recovers normal; Effective: sings and symptoms takes a turn for the better or major part takes a turn for the better, thyroid function decline more than 50% or T3, T4 have a decline; Invalid: after treatment, sings and symptoms is without improvement, check serum T 3, T4 value are without significant change.

4 courses for the treatment of of medication treatment, observe 6 months.Take the matched group of other medicines and take gained hyperthyroidism disease of the present invention and blood and to nourish heart the Comparison of therapeutic of experimental group of medicated wine, result is as shown in table 1:

Table 1

therapeutic effect: take gained hyperthyroidism disease of the present invention and blood and to nourish heart healing 99 people (cure rate is up to 66%) of medicated wine, effective 44 people (obvious effective rate 29.33%), invalid 7 people (inefficiency 4.67%), total effective rate reaches 95.33%.And take healing 20 people (cure rate only reaches 40%) of other products, effective 19 people (obvious effective rate 38%), invalid number but up to 11 people (inefficiency reaches 22%), effective percentage only 78%.Observe remission status within 4 courses for the treatment of: take gained hyperthyroidism disease of the present invention and ratio that each symptom that blood nourishes heart medicated wine is eased apparently higher than the remission ratio using other medicine.Gained hyperthyroidism disease of the present invention and blood nourish heart the evident in efficacy of medicated wine, bring Gospel to vast hyperthyroid patient.

Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (10)

1. hyperthyroidism disease and blood nourish heart medicated wine, it is characterized in that, take off the primary raw material stating weight proportion and be prepared from: Pericarpium Citri Reticulatae 15-25 part; Fructus Citri Sarcodactylis 10-20 part; Rhizoma Polygonati Odorati 15-30 part; Rhizoma Pinelliae 9-18 part; Thallus Laminariae (Thallus Eckloniae) 15-20 part; Sargassum 9-18 part; Concha Ostreae 8-16 part; Fructus Lycii 10-20 part; Ustilago crameri Koern. 5-8 part; Herba Violae 4-6 part; Potassium iodide 2-3 part; Crystal sugar 15-30 part; Caulis Perillae 9-12 part; Fructus Aurantii 10-16 part; Flos Caryophylli 6-9 part; Radix Paeoniae Alba 10-25 part; Spica Prunellae 8-12 part; Bulbus Fritillariae Thunbergii 8-12 part; Radix Scrophulariae 9-15 part; Rhizoma Dioscoreae Bulbiferae 4-9 part.

2. hyperthyroidism disease according to claim 1 and blood nourish heart medicated wine, it is characterized in that, take off the primary raw material stating weight proportion and be prepared from: Pericarpium Citri Reticulatae 18-22 part; Fructus Citri Sarcodactylis 13-17 part; Rhizoma Polygonati Odorati 20-25 part; Rhizoma Pinelliae 12-15 part; Thallus Laminariae (Thallus Eckloniae) 16-19 part; Sargassum 12-15 part; Concha Ostreae 11-13 part; Fructus Lycii 13-17 part; Ustilago crameri Koern. 6-7 part; Herba Violae 4.5-5.5 part; Potassium iodide 2.3-2.7 part; Crystal sugar 20-25 part; Caulis Perillae 10-11 part; Fructus Aurantii 12-14 part; Flos Caryophylli 7-8 part; Radix Paeoniae Alba 15-20 part; Spica Prunellae 9-11 part; Bulbus Fritillariae Thunbergii 9-11 part; Radix Scrophulariae 11-13 part; Rhizoma Dioscoreae Bulbiferae 5-8 part.

3. hyperthyroidism disease according to claim 1 and blood nourish heart medicated wine, it is characterized in that, take off the primary raw material stating weight proportion and be prepared from: Pericarpium Citri Reticulatae 20 parts; Fructus Citri Sarcodactylis 15 parts; Rhizoma Polygonati Odorati 22 parts; Rhizoma Pinelliae 13 parts; Thallus Laminariae (Thallus Eckloniae) 17 parts; Sargassum 13 parts; Concha Ostreae 12 parts; Fructus Lycii 15 parts; Ustilago crameri Koern. 6.5 parts; Herba Violae 5 parts; Potassium iodide 2.5 parts; 22 parts, crystal sugar; Caulis Perillae 10.5 parts; Fructus Aurantii 13 parts; Flos Caryophylli 7.5 parts; The Radix Paeoniae Alba 18 parts; Spica Prunellae 10 parts; Bulbus Fritillariae Thunbergii 10 parts; Radix Scrophulariae 12 parts; Rhizoma Dioscoreae Bulbiferae 7 parts.

4. nourish heart according to the arbitrary described hyperthyroidism disease of claim 1-3 and blood the preparation method of medicated wine, and it is characterized in that, step is as follows:

(1) Concha Ostreae and Bulbus Fritillariae Thunbergii are smashed, be placed in refractory container, intense fire heating 20-30 minute, takes out, cools;

(2) be placed in parch container by Caulis Perillae, the Radix Paeoniae Alba, Radix Scrophulariae and Rhizoma Dioscoreae Bulbiferae, moderate heat fries 20-30 minute, cools;

(3) Pericarpium Citri Reticulatae, Fructus Citri Sarcodactylis, Rhizoma Polygonati Odorati, Rhizoma Pinelliae, Thallus Laminariae (Thallus Eckloniae), Sargassum, Fructus Lycii, Herba Violae, Fructus Aurantii, Flos Caryophylli and Spica Prunellae are put into airtight non iron container, add step (1)-(2) gains and Chinese liquor, every day shakes, 20-30 days is soaked in sealing, filter and remove residue, gets upper strata clarification medicated liquor;

(4) by crystal sugar porphyrize repeatedly, mix homogeneously with Ustilago crameri Koern. and potassium iodide;

(5) step (4) gained powder is joined in step (3) gained filtrate, leave standstill 5-9 hour, get supernatant.

5. the preparation method of medicated wine according to claim 4, is characterized in that: step (1) is intense fire heating 23-27 minute preferably, is more preferably intense fire and heats 25 minutes.

6. the preparation method of medicated wine according to claim 4, is characterized in that: step (1) preferably moderate heat fries 23-27 minute, is more preferably moderate heat and fries 25 minutes.

7. the preparation method of medicated wine according to claim 4, is characterized in that: the concentration that step (3) preferably adds Chinese liquor is 50o-60 °, and being more preferably the concentration adding Chinese liquor is 55o.

8. the preparation method of medicated wine according to claim 4, is characterized in that: the Chinese liquor of the preferred Sorghum vulgare Pers. brew of step (3), consumption is 10-15 times of total quality of medicinal material, and be more preferably the Chinese liquor of Sorghum vulgare Pers. brew, consumption is 12 times of total quality of medicinal material.

9. the preparation method of medicated wine according to claim 4, is characterized in that: step (3) preferably sealing soaks 23-27 days, is more preferably sealing immersion 25 days.

10. the preparation method of medicated wine according to claim 4, is characterized in that: step (5) preferably leaves standstill 6-8 hour, is more preferably standing 7 hours.