CN1611489A - 笨并咪唑化合物的合成中间体及其制造方法 - Google Patents

笨并咪唑化合物的合成中间体及其制造方法 Download PDF

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Publication number
CN1611489A
CN1611489A CNA2004100578874A CN200410057887A CN1611489A CN 1611489 A CN1611489 A CN 1611489A CN A2004100578874 A CNA2004100578874 A CN A2004100578874A CN 200410057887 A CN200410057887 A CN 200410057887A CN 1611489 A CN1611489 A CN 1611489A
Authority
CN
China
Prior art keywords
compound
acceptable salt
boc
pharmacy acceptable
hydrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA2004100578874A
Other languages
English (en)
Chinese (zh)
Inventor
贵志直文
中村嘉孝
阿边成己
竹林絜矩
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Publication of CN1611489A publication Critical patent/CN1611489A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/26—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
    • C07C271/28—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a non-condensed six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CNA2004100578874A 1999-06-28 2000-06-27 笨并咪唑化合物的合成中间体及其制造方法 Pending CN1611489A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP18189899 1999-06-28
JP181898/1999 1999-06-28

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CNB008119864A Division CN1249024C (zh) 1999-06-28 2000-06-27 苯并咪唑化合物的合成中间体及其制造方法

Publications (1)

Publication Number Publication Date
CN1611489A true CN1611489A (zh) 2005-05-04

Family

ID=16108822

Family Applications (2)

Application Number Title Priority Date Filing Date
CNA2004100578874A Pending CN1611489A (zh) 1999-06-28 2000-06-27 笨并咪唑化合物的合成中间体及其制造方法
CNB008119864A Expired - Fee Related CN1249024C (zh) 1999-06-28 2000-06-27 苯并咪唑化合物的合成中间体及其制造方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CNB008119864A Expired - Fee Related CN1249024C (zh) 1999-06-28 2000-06-27 苯并咪唑化合物的合成中间体及其制造方法

Country Status (19)

Country Link
US (2) US6525220B2 (hu)
EP (2) EP1191019B1 (hu)
KR (1) KR100731946B1 (hu)
CN (2) CN1611489A (hu)
AT (1) ATE336482T1 (hu)
AU (1) AU5570000A (hu)
CA (1) CA2377233C (hu)
CZ (1) CZ20014412A3 (hu)
DE (1) DE60030118T2 (hu)
ES (1) ES2270843T3 (hu)
HK (1) HK1044932A1 (hu)
HU (1) HUP0201559A3 (hu)
IL (2) IL146916A0 (hu)
MX (1) MXPA02000069A (hu)
NO (1) NO20016366L (hu)
PL (1) PL352383A1 (hu)
RU (1) RU2224742C2 (hu)
TW (1) TWI262180B (hu)
WO (1) WO2001000570A1 (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6489346B1 (en) * 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
KR101150739B1 (ko) * 2004-09-28 2012-06-08 상꾜 가부시키가이샤 6-치환-1-메틸-1-ｈ-벤즈이미다졸 유도체의 제조 방법 및 그 제조 중간체
TW200637856A (en) * 2005-01-24 2006-11-01 Sankyo Co Process for producing thiazolidinedion compound and intermediate thereof
CA2781800A1 (en) 2009-11-26 2011-06-03 Daiichi Sankyo Company, Limited Method for manufacturing a 6-substituted 1-methyl-1h-benzimidazole derivative and an intermediate of said method

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0745600A (ja) * 1993-01-20 1995-02-14 Hitachi Ltd 液中異物付着防止溶液とそれを用いたエッチング方法及び装置
US5652237A (en) * 1994-09-09 1997-07-29 Warner-Lambert Company 2-substituted-4H-3, 1-benzoxazin-4-ones and benzthiazin-4-ones as inhibitors of complement C1r protease for the treatment of inflammatory processes
IL118474A (en) 1995-06-01 2001-08-08 Sankyo Co Benzimideol derivatives and pharmaceutical preparations containing them
PL200859B1 (pl) * 1997-10-08 2009-02-27 Sankyo Co Podstawiony skondensowany związek heterocykliczny, kompozycja farmaceutyczna zawierająca podstawiony skondensowany związek heterocykliczny oraz zastosowanie podstawionego skondensowanego związku heterocyklicznego

Also Published As

Publication number Publication date
HUP0201559A2 (en) 2002-08-28
EP1191019A1 (en) 2002-03-27
HK1044932A1 (en) 2002-11-08
NO20016366D0 (no) 2001-12-27
CA2377233C (en) 2009-03-10
CN1371360A (zh) 2002-09-25
HUP0201559A3 (en) 2004-03-01
EP1191019B1 (en) 2006-08-16
US20030008907A1 (en) 2003-01-09
RU2224742C2 (ru) 2004-02-27
CA2377233A1 (en) 2001-01-04
DE60030118T2 (de) 2007-03-15
DE60030118D1 (de) 2006-09-28
US6525220B2 (en) 2003-02-25
US6753347B2 (en) 2004-06-22
ES2270843T3 (es) 2007-04-16
KR20020087835A (ko) 2002-11-23
MXPA02000069A (es) 2002-07-02
WO2001000570A1 (fr) 2001-01-04
ATE336482T1 (de) 2006-09-15
NO20016366L (no) 2002-02-27
PL352383A1 (en) 2003-08-25
KR100731946B1 (ko) 2007-06-25
TWI262180B (en) 2006-09-21
US20030199580A1 (en) 2003-10-23
IL146916A0 (en) 2002-08-14
IL146916A (en) 2008-07-08
CN1249024C (zh) 2006-04-05
EP1191019A4 (en) 2004-06-02
AU5570000A (en) 2001-01-31
CZ20014412A3 (cs) 2002-04-17
EP1607385A1 (en) 2005-12-21

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Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication