CN1608637A - 一种抗恶性肿瘤药物的制备方法 - Google Patents
一种抗恶性肿瘤药物的制备方法 Download PDFInfo
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- CN1608637A CN1608637A CNA2003101037170A CN200310103717A CN1608637A CN 1608637 A CN1608637 A CN 1608637A CN A2003101037170 A CNA2003101037170 A CN A2003101037170A CN 200310103717 A CN200310103717 A CN 200310103717A CN 1608637 A CN1608637 A CN 1608637A
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Abstract
本发明涉及一种以天然植物药材为主要药用成分的具有抗恶性肿瘤的药物的制备方法。本发明所述的药物的制备方法由以下步骤组成：一、按重量配比取丁香7－13、木香7－13进行蒸馏，分别得到挥发油和残渣，待用；二、按重量配比取阿魏7－13、九香虫11－18、诃子10－15、姜黄8－25、大黄1－25，粉碎后加入上述残渣，用乙醇或水提取，提取液经浓缩后干燥，粉碎；三、按重量配比取冬虫夏草1－4粉碎成粉，将(一)所得挥发油、(二)所得粉碎物与之混合均匀；四、按照口服制剂常规制备工艺制成口服制剂。本发明所述工艺系根据本发明配方特点而制定，方法简单、易行且有效。
Description
技术领域
本发明涉及一种以天然植物药材为主要药用成分的具有抗恶性肿瘤的药物的制备方法。
技术背景
由于恶性肿瘤的难治性，数世纪以来，各国学者除通过改良手术，寻求提高放化疗疗效的途径外，从传统医学中寻找有价值的线索，增加治疗手段已成为征服恶性肿瘤的一种重要途径。中医药及民族药制剂的综合研究一直是肿瘤防治界寻找解决恶性肿瘤难治性的有效方法之一。而这些药物的制备方法对药物的疗效也能起到较为关键的作用。
发明内容
本发明的目的在于提供一种抗恶性肿瘤的药物的制备方法。
本发明所述的抗恶性肿瘤药物的制备方法由以下步骤组成：
一、按重量配比取丁香7-13、木香7-13进行蒸馏，分别得到挥发油和残渣，待用；
二、按重量配比取阿魏7-13、九香虫11-18、诃子10-15、姜黄8-25、大黄1-25，粉碎后加入上述残渣，用乙醇或水提取，提取液经浓缩后干燥，粉碎；
三、按重量配比取冬虫夏草1-4粉碎成粉，将(一)所得挥发油、(二)所得粉碎物与之混合均匀；
四、按照口服制剂常规制备工艺制成口服制剂。
本发明所述工艺系根据本发明配方特点而制定，方法简单、易行且有效。
具体实施方式
实施例1：
按重量配比取丁香10份、木香12份，进行蒸馏后取挥发油和残渣备用。取阿魏10份、九香虫16份、诃子13份、姜黄22份、大黄18份，加入上述残渣，用水煮三次，合并水煮液，减压浓缩，加65-95％(体积比)乙醇静止沉淀24-48小时，取上清液，减压回收乙醇，得到浸膏，将浸膏干燥后粉碎，待用；按重量配比取冬虫夏草4份，粉碎成粉，加入蒸发油和浸膏粉碎物，混合均匀；以此作为药用有效成分，按照常规片剂制作方法，加入辅料，制成片剂。
实施例2：
按重量配比取丁香8份、木香11份，蒸馏后取挥发油及残渣备用。取阿魏13份、九香虫17份、诃子14份、姜黄21份、大黄25份，加入上述残渣，加入65-95％(体积比)乙醇溶液进行提取后，减压回收乙醇，得到浸膏，将浸膏干燥后粉碎，待用；按重量配比取冬虫夏草2份，粉碎成粉，三者混合均匀；以此作为药用有效成分，按照常规胶囊剂制作方法，加入辅料，制成胶囊剂。
Claims (1)
1、一种抗恶性肿瘤药物的制备方法，其特征在于由以下步骤组成：
一、按重量配比取丁香7-13、木香7-13进行蒸馏，分别得到挥发油和残渣，待用；
二、按重量配比取阿魏7-13、九香虫11-18、诃子10-15、姜黄8-25、大黄1-25，粉碎后加入上述残渣，用乙醇或水提取，提取液经浓缩后干燥，粉碎；
三、按重量配比取冬虫夏草1-4粉碎成粉，将(一)所得挥发油、(二)所得粉碎物与之混合均匀；
四、按照口服制剂常规制备工艺制成口服制剂。
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| CNB2003101037170A CN1289136C (zh) | 2003-10-24 | 2003-10-24 | 一种抗恶性肿瘤药物的制备方法 |
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| CNB2003101037170A CN1289136C (zh) | 2003-10-24 | 2003-10-24 | 一种抗恶性肿瘤药物的制备方法 |
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| CN1608637A true CN1608637A (zh) | 2005-04-27 |
| CN1289136C CN1289136C (zh) | 2006-12-13 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008096343A1 (en) * | 2007-02-04 | 2008-08-14 | Menachem Rabinovich | Turmeric compositions and methods for the preparation thereof |
| CN101352559B (zh) * | 2008-08-29 | 2011-06-15 | 温先敏 | 治疗肿瘤的药物制剂 |
| CN105693806A (zh) * | 2016-04-23 | 2016-06-22 | 何华琼 | 一种二甲磺酸阿米三嗪的药物组合物及其医药用途 |
-
2003
- 2003-10-24 CN CNB2003101037170A patent/CN1289136C/zh not_active Expired - Lifetime
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008096343A1 (en) * | 2007-02-04 | 2008-08-14 | Menachem Rabinovich | Turmeric compositions and methods for the preparation thereof |
| CN101352559B (zh) * | 2008-08-29 | 2011-06-15 | 温先敏 | 治疗肿瘤的药物制剂 |
| CN105693806A (zh) * | 2016-04-23 | 2016-06-22 | 何华琼 | 一种二甲磺酸阿米三嗪的药物组合物及其医药用途 |
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| CN1289136C (zh) | 2006-12-13 |
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