CN1596966A - Compound formule chinaroot greenbrier capsule and its preparation method - Google Patents

Compound formule chinaroot greenbrier capsule and its preparation method Download PDF

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Publication number
CN1596966A
CN1596966A CNA2004100466154A CN200410046615A CN1596966A CN 1596966 A CN1596966 A CN 1596966A CN A2004100466154 A CNA2004100466154 A CN A2004100466154A CN 200410046615 A CN200410046615 A CN 200410046615A CN 1596966 A CN1596966 A CN 1596966A
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China
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capsule
rhizoma smilacis
smilacis chinensis
bright
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CNA2004100466154A
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CN1270753C (en
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单建华
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Abstract

A Chinese medicine in the form of capsule for treating lung cancer and cervix cancer is prepared from 8 Chinese-medicinal materials including smilax China, wolfberry fruit, jujube, ground bettle, etc. Its preparing process is also disclosed.

Description

Compound recipe Rhizoma Smilacis Chinensis capsule and preparation method thereof
Technical field:
The present invention relates to a kind of Chinese medicinal capsule agent and process for making thereof, relate in particular to a kind of compound recipe Rhizoma Smilacis Chinensis capsule and preparation method thereof.
Background technology:
Chinese medicine compound Rhizoma Smilacis Chinensis preparation has heat-clearing and toxic substances removing, hard masses softening and resolving, and the effect of enriching yin boost qi shows through modern medicine study, this product is used for the treatment of pulmonary carcinoma, cervical cancer with cough, chest pain, leukorrhagia is unusual etc., and symptom all has curative effect preferably.Existing compound recipe Rhizoma Smilacis Chinensis Chinese medicine preparation is a water preparation, carries, takes all extremely inconvenient.
Summary of the invention:
The purpose of this invention is to provide a kind of compound recipe Rhizoma Smilacis Chinensis capsule that is convenient for carrying, takes and preparation method thereof, can satisfy the needs of medical treatment better.
Technical solution of the present invention is a kind of heat-clearing and toxic substances removing that has, hard masses softening and resolving, the effect of enriching yin boost qi, the Chinese medicine preparation of treatment pulmonary carcinoma, cervical cancer is characterized in that it is that main component is the capsule of Rhizoma Smilacis Chinensis, Herba Houttuyniae, Radix Ranunculi Ternati, Eupolyphaga Seu Steleophaga, Flos Farfarae, Fructus Lycii, Fructus Jujubae (enucleation), bright Ophicephalus argus.
The preparation method of this capsule is:
(1) main constituent and percentage by weight consumption thereof are as follows:
Rhizoma Smilacis Chinensis 10-25%, Herba Houttuyniae 10-25%, Radix Ranunculi Ternati 10-25%, Eupolyphaga Seu Steleophaga 2-15%, Flos Farfarae 2-15%, Fructus Lycii 10-25%, Fructus Jujubae (enucleation) 10-25%, bright Ophicephalus argus 5-20%;
(2) bright Ophicephalus argus is cut into chunks after, decoct with water secondary with all the other seven flavor medicines, for the first time add 8 times of water gagings, decocted 1.5 hours, for the second time add 6 times of water gagings, decocted collecting decoction 1 hour, filter, filtrate is concentrated into the extractum that relative density is 1.38~1.40 (60~65 ℃ of heat are surveyed), and is standby;
(3) in the extractum of (2) gained, add the right amount of auxiliary materials mixing, granulate, drying, granule is standby;
The granulation adjuvant is one or more a various combination in lactose, calcium sulfate, sucrose, microcrystalline Cellulose, soluble starch, pregelatinized Starch, carboxymethyl starch sodium, xylitol, starch, dextrin, sodium carboxymethyl cellulose, the low-substituted hydroxypropyl cellulose;
(4) granule by (3) gained adds an amount of adjuvant mix homogeneously, encapsulating capsule; Or do not add the direct encapsulating capsule of adjuvant;
To add adjuvant be one or more various combination in Pulvis Talci, magnesium stearate, the micropowder silica gel;
In the above-mentioned preparation method, the optimum weight percentage ratio of main constituent is: Rhizoma Smilacis Chinensis 15.96%, Herba Houttuyniae 15.96%, Radix Ranunculi Ternati 15.96%, Eupolyphaga Seu Steleophaga 5.32%, Flos Farfarae 5.32%, Fructus Lycii 15.96%, Fructus Jujubae (enucleation) 15.96%, bright Ophicephalus argus 9.56%;
The specific embodiment:
The present invention further specifies as follows in conjunction with specific embodiments:
A kind of compound recipe Rhizoma Smilacis Chinensis capsule, be a kind of heat-clearing and toxic substances removing that has, hard masses softening and resolving, the effect of enriching yin boost qi, the Chinese medicine preparation of treatment pulmonary carcinoma, cervical cancer, it contains main component and is: Rhizoma Smilacis Chinensis, Herba Houttuyniae, Radix Ranunculi Ternati, Eupolyphaga Seu Steleophaga, Flos Farfarae, Fructus Lycii, Fructus Jujubae (enucleation), bright Ophicephalus argus.
To produce 1000 capsules is example, and its preparation method is:
(1) it is as follows to get the consumption of each constituent:
Rhizoma Smilacis Chinensis 750g, Herba Houttuyniae 750g, Radix Ranunculi Ternati 750g, Eupolyphaga Seu Steleophaga 250g, Flos Farfarae 250g, Fructus Lycii 750g, Fructus Jujubae (enucleation) 750g, bright Ophicephalus argus 450g;
(2) bright Ophicephalus argus is cut into chunks after, decoct with water secondary with all the other seven flavor medicines, for the first time add 8 times of water gagings, decocted 1.5 hours, for the second time add 6 times of water gagings, decocted collecting decoction 1 hour, filter, filtrate is concentrated into the extractum that relative density is 1.38~1.40 (60~65 ℃ of heat are surveyed), and is standby;
(4) in (3) gained dried cream powder, add an amount of adjuvant mix homogeneously, granulate drying;
Adjuvant is 10% microcrystalline Cellulose, and its percentage ratio metering radix is the total amount of dried cream powder;
(5) by adding an amount of adjuvant mix homogeneously, encapsulating capsule behind the granule granulate of (4) gained;
Adjuvant is 3% micropowder silica gel, and its percentage ratio metering radix is the total amount of dried cream powder.
Advantage of the present invention is:
This capsule is made up of medicine and filler, is easy to carry, and disintegrate rapidly, little, the taking convenience of dose help improving curative effect.

Claims (3)

1, a kind of compound recipe Rhizoma Smilacis Chinensis capsule, it is a kind of heat-clearing and toxic substances removing that has, hard masses softening and resolving, the effect of enriching yin boost qi, the Chinese medicine preparation of treatment pulmonary carcinoma, cervical cancer is characterized in that it is that main component is the capsule of Rhizoma Smilacis Chinensis, Herba Houttuyniae, Radix Ranunculi Ternati, Eupolyphaga Seu Steleophaga, Flos Farfarae, Fructus Lycii, Fructus Jujubae (enucleation), bright Ophicephalus argus.
2, the capsular preparation method of a kind of compound recipe Rhizoma Smilacis Chinensis is characterized in that:
(1) constituent and percentage by weight consumption thereof are as follows:
Rhizoma Smilacis Chinensis 10-25%, Herba Houttuyniae 10-25%, Radix Ranunculi Ternati 10-25%, Eupolyphaga Seu Steleophaga 2-15%, Flos Farfarae 2-15%, Fructus Lycii 10-25%, Fructus Jujubae (enucleation) 10-25%, bright Ophicephalus argus 5-20%;
(2) bright Ophicephalus argus is cut into chunks after, decoct with water secondary with all the other seven flavor medicines, for the first time add 8 times of water gagings, decocted 1.5 hours, for the second time add 6 times of water gagings, decocted collecting decoction 1 hour, filter, filtrate is concentrated into the extractum that relative density is 1.38~1.40 (60~65 ℃ of heat are surveyed), and is standby;
(3) in the extractum of (2) gained, add the right amount of auxiliary materials mixing, granulate, drying, granule is standby;
The granulation adjuvant is one or more a various combination in lactose, calcium sulfate, sucrose, microcrystalline Cellulose, soluble starch, pregelatinized Starch, carboxymethyl starch sodium, xylitol, starch, dextrin, sodium carboxymethyl cellulose, the low-substituted hydroxypropyl cellulose;
(4) granule by (3) gained adds an amount of adjuvant mix homogeneously, encapsulating capsule; Or do not add the direct encapsulating capsule of adjuvant;
To add adjuvant be one or more various combination in Pulvis Talci, magnesium stearate, the micropowder silica gel;
3, the capsular preparation method of compound recipe Rhizoma Smilacis Chinensis according to claim 2 is characterized in that the optimum weight percentage ratio of its main constituent is:
Rhizoma Smilacis Chinensis 15.96%, Herba Houttuyniae 15.96%, Radix Ranunculi Ternati 15.96%, Eupolyphaga Seu Steleophaga 5.32%, Flos Farfarae 5.32%, Fructus Lycii 15.96%, Fructus Jujubae (enucleation) 15.96%, bright Ophicephalus argus 9.56%;
CNB2004100466154A 2004-07-30 2004-07-30 Compound formule chinaroot greenbrier capsule and its preparation method Expired - Fee Related CN1270753C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNB2004100466154A CN1270753C (en) 2004-07-30 2004-07-30 Compound formule chinaroot greenbrier capsule and its preparation method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNB2004100466154A CN1270753C (en) 2004-07-30 2004-07-30 Compound formule chinaroot greenbrier capsule and its preparation method

Publications (2)

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CN1596966A true CN1596966A (en) 2005-03-23
CN1270753C CN1270753C (en) 2006-08-23

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CNB2004100466154A Expired - Fee Related CN1270753C (en) 2004-07-30 2004-07-30 Compound formule chinaroot greenbrier capsule and its preparation method

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