CN1270753C - Compound formule chinaroot greenbrier capsule and its preparation method - Google Patents
Compound formule chinaroot greenbrier capsule and its preparation method Download PDFInfo
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- CN1270753C CN1270753C CNB2004100466154A CN200410046615A CN1270753C CN 1270753 C CN1270753 C CN 1270753C CN B2004100466154 A CNB2004100466154 A CN B2004100466154A CN 200410046615 A CN200410046615 A CN 200410046615A CN 1270753 C CN1270753 C CN 1270753C
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- rhizoma smilacis
- smilacis chinensis
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Abstract
The present invention relates to a compound formula chinaroot greenbrier capsule which has the effects of clearing away heat and toxic material, softening and resolving hard mass, nourishing yin and invigorating qi, and is a Chinese materia medica preparation for treating lung cancer and cervical cancer. The capsule comprises the main components of the following percent by weight: 10 to 25% of chinaroot greenbrier, 10 to 25% of heartleaf houttuynia herb, 10 to 25% of catclaw buttercup root, 10 to 25% of barbary wolfberry fruit, 10 to 25% of enucleate Chinese date, 2 to 15% of ground beetle, 2 to 15% of common coltsfoot flower, 5 to 20% of fresh snakehead and a right amount of auxiliary materials. A preparation method of the present invention comprises: chopping the fresh snakehead into segments, decocting the fresh snakehead segments and other seven medicines with water twice, adding 8 times of water at the first time, decocting the medicinal liquor for 1.5 hours, adding 6 times of water at the second time, decocting the medicinal liquor for 1 hour, combining the decoction liquor, filtering, concentrating the filter liquor to extractum with the relative density of 1.38 to 1.40 at 60 to 65 DEG C, adding a right amount of auxiliary materials into the extractum, blending uniformly, granulating, drying, finishing the granule, adding a right amount of auxiliary materials into the dry granule, blending uniformly, filling into the capsule, or directly filling into the capsule without adding the auxiliary materials. The capsule is composed of medicines and filling agents and has the advantages of portability, rapid disintegration, small dosage and convenient administration; the capsule is favorable for the enhancement of therapeutic effect.
Description
Technical field:
The present invention relates to a kind of Chinese medicinal capsule agent and process for making thereof, relate in particular to a kind of compound recipe Rhizoma Smilacis Chinensis capsule and preparation method thereof.
Background technology:
Chinese medicine compound Rhizoma Smilacis Chinensis preparation has heat-clearing and toxic substances removing, hard masses softening and resolving, and the effect of enriching yin boost qi shows through modern medicine study, this product is used for the treatment of pulmonary carcinoma, cervical cancer with cough, chest pain, leukorrhagia is unusual etc., and symptom all has curative effect preferably.Existing compound recipe Rhizoma Smilacis Chinensis Chinese medicine preparation is a water preparation, carries, takes all extremely inconvenient.
Summary of the invention:
The purpose of this invention is to provide a kind of compound recipe Rhizoma Smilacis Chinensis capsule that is convenient for carrying, takes and preparation method thereof, can satisfy the needs of medical treatment better.
Technical solution of the present invention is a kind of heat-clearing and toxic substances removing that has, hard masses softening and resolving, the effect of enriching yin boost qi, the Chinese medicine preparation of treatment pulmonary carcinoma, cervical cancer is characterized in that it is that main component is the capsule of Rhizoma Smilacis Chinensis, Herba Houttuyniae, Radix Ranunculi Ternati, Eupolyphaga Seu Steleophaga, Flos Farfarae, Fructus Lycii, Fructus Jujubae (enucleation), bright Ophicephalus argus.
The preparation method of this capsule is:
(1) main constituent and percentage by weight consumption thereof are as follows:
Rhizoma Smilacis Chinensis 10-25%, Herba Houttuyniae 10-25%, Radix Ranunculi Ternati 10-25%, Eupolyphaga Seu Steleophaga 2-15%, Flos Farfarae 2-15%, Fructus Lycii 10-25%, Fructus Jujubae (enucleation) 10-25%, bright Ophicephalus argus 5-20%;
(2) bright Ophicephalus argus is cut into chunks after, decoct with water secondary with all the other seven flavor medicines, for the first time add 8 times of water gagings, decocted 1.5 hours, for the second time add 6 times of water gagings, decocted collecting decoction 1 hour, filter, filtrate is concentrated into the extractum that relative density is 1.38～1.40 (60～65 ℃ of heat are surveyed), and is standby;
(3) in the extractum of (2) gained, add the right amount of auxiliary materials mixing, granulate, drying, granule is standby;
The granulation adjuvant is one or more a various combination in lactose, calcium sulfate, sucrose, microcrystalline Cellulose, soluble starch, pregelatinized Starch, carboxymethyl starch sodium, xylitol, starch, dextrin, sodium carboxymethyl cellulose, the low-substituted hydroxypropyl cellulose;
(4) granule by (3) gained adds an amount of adjuvant mix homogeneously, encapsulating capsule; Or do not add the direct encapsulating capsule of adjuvant;
To add adjuvant be one or more various combination in Pulvis Talci, magnesium stearate, the micropowder silica gel;
In the above-mentioned preparation method, the optimum weight percentage ratio of main constituent is: Rhizoma Smilacis Chinensis 15.96%, Herba Houttuyniae 15.96%, Radix Ranunculi Ternati 15.96%, Eupolyphaga Seu Steleophaga 5.32%, Flos Farfarae 5.32%, Fructus Lycii 15.96%, Fructus Jujubae (enucleation) 15.96%, bright Ophicephalus argus 9.56%;
The specific embodiment:
The present invention further specifies as follows in conjunction with specific embodiments:
A kind of compound recipe Rhizoma Smilacis Chinensis capsule, be a kind of heat-clearing and toxic substances removing that has, hard masses softening and resolving, the effect of enriching yin boost qi, the Chinese medicine preparation of treatment pulmonary carcinoma, cervical cancer, it contains main component and is: Rhizoma Smilacis Chinensis, Herba Houttuyniae, Radix Ranunculi Ternati, Eupolyphaga Seu Steleophaga, Flos Farfarae, Fructus Lycii, Fructus Jujubae (enucleation), bright Ophicephalus argus.
To produce 1000 capsules is example, and its preparation method is:
(1) it is as follows to get the consumption of each constituent:
Rhizoma Smilacis Chinensis 750g, Herba Houttuyniae 750g, Radix Ranunculi Ternati 750g, Eupolyphaga Seu Steleophaga 250g, Flos Farfarae 250g, Fructus Lycii 750g, Fructus Jujubae (enucleation) 750g, bright Ophicephalus argus 450g;
(2) bright Ophicephalus argus is cut into chunks after, decoct with water secondary with all the other seven flavor medicines, for the first time add 8 times of water gagings, decocted 1.5 hours, for the second time add 6 times of water gagings, decocted collecting decoction 1 hour, filter, filtrate is concentrated into the extractum that relative density is 1.38～1.40 (60～65 ℃ of heat are surveyed), and is standby;
(4) in (3) gained dried cream powder, add an amount of adjuvant mix homogeneously, granulate drying;
Adjuvant is 10% microcrystalline Cellulose, and its percentage ratio metering radix is the total amount of dried cream powder;
(5) by adding an amount of adjuvant mix homogeneously, encapsulating capsule behind the granule granulate of (4) gained;
Adjuvant is 3% micropowder silica gel, and its percentage ratio metering radix is the total amount of dried cream powder.
Advantage of the present invention is:
This capsule is made up of medicine and filler, is easy to carry rapidly disintegration, little, the side of taking of dose Just, be conducive to improve curative effect.
Claims (3)
1, a kind of compound recipe Rhizoma Smilacis Chinensis capsule is characterized in that it is that the crude drug percentage by weight is the capsule of Rhizoma Smilacis Chinensis 10-25%, Herba Houttuyniae 10-25%, Radix Ranunculi Ternati 10-25%, Eupolyphaga Seu Steleophaga 2-15%, Flos Farfarae 2-15%, Fructus Lycii 10-25%, Fructus Jujubae (pitted) 10-25%, bright Ophicephalus argus 5-20%.
2, the capsular preparation method of a kind of compound recipe Rhizoma Smilacis Chinensis is characterized in that:
(1) crude drug percentage by weight consumption is as follows:
Rhizoma Smilacis Chinensis 10-25%, Herba Houttuyniae 10-25%, Radix Ranunculi Ternati 10-25%, Eupolyphaga Seu Steleophaga 2-15%, Flos Farfarae 2-15%, Fructus Lycii 10-25%, Fructus Jujubae (pitted) 10-25%, bright Ophicephalus argus 5-20%;
(2) bright Ophicephalus argus is cut into chunks after, decoct with water secondary with all the other seven flavor medicines, for the first time add 8 times of water gagings, decocted 1.5 hours, for the second time add 6 times of water gagings, decocted collecting decoction 1 hour, filter, filtrate is concentrated into 60 ℃-65 ℃ heat survey relative densities and is the extractum of 1.38-1.40, and is standby;
(3) in the extractum of (2) gained, add the right amount of auxiliary materials mixing, granulate, drying, granule is standby;
Adjuvant is one or more a various combination in lactose, calcium sulfate, multitudinous sugar, microcrystalline Cellulose, soluble starch, pregelatinized Starch, Sodium Hydroxymethyl Stalcs, xylitol, starch, dextrin, carboxymethyl starch sodium, the low-substituted hydroxypropyl cellulose;
(4) an amount of adjuvant mix homogeneously, encapsulating capsule will be added in (3) gained granule; Or do not add the direct encapsulating capsule of adjuvant, to add adjuvant be one or more various combination in Pulvis Talci, magnesium stearate, the micropowder silica gel.
3, the capsular preparation method of compound recipe Rhizoma Smilacis Chinensis according to claim 2 is characterized in that its crude drug percentage by weight is:
Rhizoma Smilacis Chinensis 15.96%, Herba Houttuyniae 15.96%, Radix Ranunculi Ternati 15.96%, Eupolyphaga Seu Steleophaga 5.32%, Flos Farfarae 5.32%, Fructus Lycii 15.96%, Fructus Jujubae (pitted) 15.96%, bright Ophicephalus argus 9.56%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100466154A CN1270753C (en) | 2004-07-30 | 2004-07-30 | Compound formule chinaroot greenbrier capsule and its preparation method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100466154A CN1270753C (en) | 2004-07-30 | 2004-07-30 | Compound formule chinaroot greenbrier capsule and its preparation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1596966A CN1596966A (en) | 2005-03-23 |
| CN1270753C true CN1270753C (en) | 2006-08-23 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2004100466154A Expired - Fee Related CN1270753C (en) | 2004-07-30 | 2004-07-30 | Compound formule chinaroot greenbrier capsule and its preparation method |
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| Country | Link |
|---|---|
| CN (1) | CN1270753C (en) |
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2004
- 2004-07-30 CN CNB2004100466154A patent/CN1270753C/en not_active Expired - Fee Related
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| CN1596966A (en) | 2005-03-23 |
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