CN1560088A - Preparaton process of glucoside polyose selenide - Google Patents
Preparaton process of glucoside polyose selenide Download PDFInfo
- Publication number
- CN1560088A CN1560088A CNA2004100127850A CN200410012785A CN1560088A CN 1560088 A CN1560088 A CN 1560088A CN A2004100127850 A CNA2004100127850 A CN A2004100127850A CN 200410012785 A CN200410012785 A CN 200410012785A CN 1560088 A CN1560088 A CN 1560088A
- Authority
- CN
- China
- Prior art keywords
- selenizing
- preparation
- konjac glucomanna
- selenium
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Fruits And Vegetables (AREA)
Abstract
The invention discloses a selenoglucomannan preparing method, combining the selenium with glucomannan on a certain condition to achieve the purpose of producing selenium-containing selenoglucomannan. It oxidizes the selenium into Se6+ ion water solution by oxidant; takes the Se6+ ion water solution and adds in alcohol and hydrochloric acid, to make the alcohol content in the solution at 5%-10% and hydrochloric acid content at 1% about; adds glucomannan in a seleno-reaction liquor to make seleno reaction; adds in alcohol to deposit selenoglucomannan; separates and dehydrates selenoglucomannan deposit, and then dries to make it at once.
Description
Technical field
The present invention relates to a kind of preparation method of selenizing konjac glucomanna.
Background technology
Trace element-selenium (Selenium is the trace element of needed by human Se), have anti-oxidant, remove free radical, anticancer, the vital role that improves and regulate immunologic function, have the physiological function of similar Regular Insulin.Konjaku is the stem tuber of Rhizoma Arisaematis material (Araceae) Amorphophallus (Amorphophallus blume) per nnial herb, extensively is distributed in the Yangtze valley and areas to the south.Contain in the konjaku abundant konjac glucomanna (Kglucomanan, KGM), have reducing blood-fat, hypoglycemic, cleaning enteron aisle, press down important health-care effect such as knurl and raise immunity and anti-oxidant, remove important physiological function such as free radical.
The advantage that contains abundant konjac glucomanna and selenium in the konjaku is combined, make having complementary functions and doubling of the two, further improve its health-care effect, the two is in conjunction with after forming new material selenizing konjac glucomanna, selenium is organised, lowered toxicity greatly, the residence time prolongs in vivo, can play one's part to the full.
No matter konjaku is at natural high selenium zone in planting process or manually executes selenium, can contain higher selenium (0.65-7.80mg/kg) in its stem tuber, but in the course of processing, can't avoid losing of selenium, be processed into behind the konjac glucomanna content of selenium atomic or detect less than.
Summary of the invention
The production method of a kind of selenizing konjac glucomanna of the present invention combines selenium with konjac glucomanna exactly under certain conditions, reaches the purpose of producing the selenizing konjac glucomanna that contains selenium.
The method of a kind of selenizing konjac glucomanna of the present invention realizes by following steps:
Se
6+The preparation of solion:, selenolite is changed into be Se with simple substance selenium or the oxygenant oxidation of selenium salt
6+Ion adds entry again and makes and contain Se
6+The ionic aqueous solution;
The preparation of selenylation reaction liquid: get Se
6+The ionic aqueous solution adds ethanol and hydrochloric acid, makes ethanol content in the solution at 5%-10%, and content of hydrochloric acid is about 1%;
Selenylation reaction: in selenylation reaction liquid, add konjac glucomanna and carry out selenylation reaction;
Reduction reaction: adding ethanol through in the solution of selenylation reaction, making through the selenizing konjac glucomanna after the selenizing to be precipitated out:
Finished product separates oven dry: with the precipitation selenizing konjac glucomanna separating and dehydrating in the reduction reaction liquid, get final product through oven dry again.
Among the preparation method of described selenizing konjac glucomanna, Se
6+It is about 500 times that the preparation of solion adds the water yield.Use concentrated hydrochloric acid in the preparation of selenylation reaction liquid.The konjac glucomanna that adds in the selenylation reaction is the 14%-40% of solution amount.Add ethanol in the reduction reaction and make that alcoholic acid content reaches more than 30% in the solution.
Selenizing konjac glucomanna preparation method of the present invention has reached selenium is combined with konjac glucomanna, and selenium more easily is absorbed by the body.For health-product market provides new product, its function is far longer than separately separately and uses, neither simple addition, and its effect anti-oxidant, that remove free radical is more powerful.
The selenizing konjac glucomanna has following function:
1, detoxication and toxicant eliminating function effect: selenium has heavy metal element and aflatoxin degradations such as antagonism lead, mercury, cadmium, removes the function of internal metabolism refuse, and konjac glucomanna itself is exactly the high-quality dietary cellulose, can clear up enteron aisle fast.Therefore, the selenizing konjac glucomanna organically combines detoxifcation and toxin expelling effect, can accelerate the drainage of poisonous substance, refuse in the body.
2, anti-cancer and kill cancer action: selenium and konjac glucomanna all can improve immunologic function; all has anti-oxidant, removing free radical; in time get rid of vivotoxin and metabolic waste; the integrity and the antimutagenic effect of protection cytolemma; the activity of degrading carcinogen in it matter; subtract the toxic side effect of falling cancer therapy drug, its anti-cancer and kill cancer action is fairly obvious.
3, blood lipid-reducing blood sugar-decreasing effect: the blood lipid-reducing blood sugar-decreasing effect of konjac glucomanna is obvious, and selenium has the effect of similar Regular Insulin, and the selenizing konjac glucomanna is best blood lipid-reducing blood sugar-decreasing product.The selenizing konjac glucomanna is high fiber article, and it can delay the gastric emptying time, reduces the absorption rate of enteron aisle to fat and glucose; Viscosity is big, adsorbable fat and glucose, delayed absorption; Can produce propionic salt in the colonic fermentation, quicken glycolysis-; Can bring into play the effect of similar Regular Insulin, quicken the metabolism of sugar; Influence the enteron aisle hormonal readiness, regulate the absorption equilibrium of fat and carbohydrate.
4, anti-ageing antiobesity action:
The selenizing konjac glucomanna has the effect of obvious reduction serum cholesterol, and combines with cholesterol, suppresses the absorption of fat and cholesterol, and the enterohepatic circulation of blocking-up cholic acid quickens the conversion of cholesterol to the cholic acid direction, and the prevention cholic acid absorbs and allows it in time discharge from ight soil; Can be decomposed the generation short chain fatty acid by enteric microorganism, and be absorbed by the body, thereby produce reducing blood lipid; Water-absorbent is strong, becomes the viscous fiber element after the suction, and the food that can slow down is the speed to small intestine from stomach, reduces the absorption of nutritive substance, and the lipid acid resultant velocity is descended, thereby reaches the effect of fat-reducing; Satiety is arranged after the suction, effect of relaxing bowel is arranged, play antiobesity action indirectly.
Owing in time drain refuse and toxin, nearly 20 kinds of selenoenzymes and activity of proteins in enhancing body Selenoperoxidase and the body make cells in vivo, organize physiologically active and the function avoiding peroxide injury and keep body, reduce the generation of disease.Therefore has the obvious effect that delays senility.
Embodiment
Embodiment; Use selenizing konjac glucomanna preparation method of the present invention, take simple substance selenium and strong oxidizer potassium permanganate carries out oxidizing reaction, obtain Se
6+The deionized water that adds 500 times behind the ion adds 95% ethanol and concentrated hydrochloric acid, makes that ethanol content is 5% in the solution, and content of hydrochloric acid is 1%; Add 15% konjac glucomanna powder again, reacting by heating liquid, controlled temperature is right at 40 ℃, reacting lowered the temperature after 15 minutes is cooled to room temperature, add ethanol again and make that ethanol content reaches more than 30% in the solution, the standing separation precipitation gets final product sedimentary selenizing konjac glucomanna oven dry.
Selenizing konjac glucomanna preparation method of the present invention is by repeatedly experiment, use the situation of different concns to carry out selenylation reaction, adopt 2.3-diaminonaphthalene method (national standard method) to detect the selenizing konjac glucomanna, selenium content is all doubly a lot of than exceeding before the reaction in the selenizing konjac glucomanna that obtains.Now will implement several groups of data of selenizing konjac glucomanna respectfully presents as follows:
| The enforcement time | Selenium content mg/kg in the raw material konjac glucomanna | Se in the reaction solution 6+Concentration mg/kg | Selenium content mg/kg in the selenizing konjac glucomanna |
| ??2003.7.14. | ??0.035 | ????140 | ??134.7 |
| ??2003.7.14. | ??0.032 | ????140 | ??128.4 |
| ??2004.2.20. | ??0.01 | ????140 | ??126.8 |
| ??2004.2.20. | ??0.015 | ????140 | ??127.1 |
| ??2004.2.15. | ??0.015 | ????140 | ??125.4 |
| ??2004.2.15. | ??0.035 | ????140 | ??133.0 |
| ??2003.12.19. | ??0.032 | ????200 | ??192.5 |
| ??2003.12.23. | ??0.01 | ????200 | ??197.3 |
By implementing the production of selenizing konjac glucomanna, can obtain the selenizing konjac glucomanna of selenium content more than 120mg/kg.
Claims (6)
1, a kind of preparation method of selenizing konjac glucomanna is characterized in that:
A, Se
6+The preparation of solion:, selenolite is changed into be Se with simple substance selenium or the oxygenant oxidation of selenium salt
6+Ion adds entry again and makes and contain Se
6+The ionic aqueous solution;
The preparation of b, selenylation reaction liquid: get Se
6+The ionic aqueous solution adds ethanol and hydrochloric acid, makes ethanol content in the solution at 5%-10%, and content of hydrochloric acid is about 1%;
C, selenylation reaction: in selenylation reaction liquid, add konjac glucomanna and carry out selenylation reaction;
D, reduction reaction: adding ethanol through in the solution of selenylation reaction, making through the selenizing konjac glucomanna after the selenizing to be precipitated out;
E, finished product separate oven dry: with the precipitation selenizing konjac glucomanna separating and dehydrating in the reduction reaction liquid, get final product through oven dry again.
2, according to the preparation method of the described selenizing konjac glucomanna of claim 1, it is characterized in that Se
6+Adding the water yield in the preparation of solion is about 500 times.
3,, it is characterized in that the hydrochloric acid that uses in the preparation of selenylation reaction liquid is concentrated hydrochloric acid according to the preparation method of the described selenizing konjac glucomanna of claim 1.
4,, it is characterized in that the konjac glucomanna amount that adds in the selenylation reaction is the 14%-40% of solution amount according to the preparation method of the described selenizing konjac glucomanna of claim 1.
5,, it is characterized in that the selenylation reaction temperature is controlled between 30 ℃-60 ℃ according to the preparation method of the described selenizing konjac glucomanna of claim 1.
6, according to the preparation method of the described selenizing konjac glucomanna of claim 1, alcoholic acid content reaches more than 30% in the solution in order to make to it is characterized in that adding in the reduction reaction amount of alcohol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2004100127850A CN1560088A (en) | 2004-02-26 | 2004-02-26 | Preparaton process of glucoside polyose selenide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2004100127850A CN1560088A (en) | 2004-02-26 | 2004-02-26 | Preparaton process of glucoside polyose selenide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1560088A true CN1560088A (en) | 2005-01-05 |
Family
ID=34440091
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2004100127850A Pending CN1560088A (en) | 2004-02-26 | 2004-02-26 | Preparaton process of glucoside polyose selenide |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1560088A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101941994A (en) * | 2010-08-23 | 2011-01-12 | 陕西科技大学 | Method for preparing selenium manno-oligosaccharide |
| WO2019019985A1 (en) * | 2017-07-27 | 2019-01-31 | 成都丽璟科技有限公司 | Selenium-containing compounds - selenocarbohydrate, selenoglucoside - and preparation methods therefor |
| WO2020000788A1 (en) | 2018-06-26 | 2020-01-02 | 爱美中科硒科技（天津）有限公司 | Esterified selenium polysaccharide and preparation method and use therefor |
| CN113662960A (en) * | 2020-05-13 | 2021-11-19 | 中国科学院大连化学物理研究所 | Application of selenoglucosamine in preventing and treating diabetes |
| CN115624179A (en) * | 2022-10-18 | 2023-01-20 | 陕西科技大学 | Acid-resistant ROS-scavenging microgel, preparation method thereof and application thereof in carrier |
-
2004
- 2004-02-26 CN CNA2004100127850A patent/CN1560088A/en active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101941994A (en) * | 2010-08-23 | 2011-01-12 | 陕西科技大学 | Method for preparing selenium manno-oligosaccharide |
| WO2019019985A1 (en) * | 2017-07-27 | 2019-01-31 | 成都丽璟科技有限公司 | Selenium-containing compounds - selenocarbohydrate, selenoglucoside - and preparation methods therefor |
| WO2020000788A1 (en) | 2018-06-26 | 2020-01-02 | 爱美中科硒科技（天津）有限公司 | Esterified selenium polysaccharide and preparation method and use therefor |
| US11345761B2 (en) | 2018-06-26 | 2022-05-31 | Ai-May Zhong Ke Selenium Technology (Tianjin) Co., Ltd | Esterified selenium polysaccharide and preparation method and use therefor |
| CN113662960A (en) * | 2020-05-13 | 2021-11-19 | 中国科学院大连化学物理研究所 | Application of selenoglucosamine in preventing and treating diabetes |
| CN115624179A (en) * | 2022-10-18 | 2023-01-20 | 陕西科技大学 | Acid-resistant ROS-scavenging microgel, preparation method thereof and application thereof in carrier |
| CN115624179B (en) * | 2022-10-18 | 2023-10-27 | 陕西科技大学 | Acid-resistant and ROS-scavenging microgel, preparation and application in carrier |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Mirzadeh et al. | Plant/algal polysaccharides extracted by microwave: A review on hypoglycemic, hypolipidemic, prebiotic, and immune-stimulatory effect | |
| JP5102435B2 (en) | Chitosan-containing polysaccharide, its production method and use | |
| CN108720030B (en) | Dietary fiber composition for targeted improvement of metabolic syndrome | |
| CN108359026B (en) | Preparation method and application of water-insoluble xylan | |
| CN103074397A (en) | Method for preparing fructo oligosaccharides by using sugarcane juices | |
| CN100537774C (en) | A kind of is the method for feedstock production oligofructose with molasses | |
| CN1560088A (en) | Preparaton process of glucoside polyose selenide | |
| CN106727888A (en) | A kind of jerusalem artichoke compound product and preparation method thereof | |
| CN109111530A (en) | A kind of complex polysaccharide and its preparation method and application with antioxidant activity | |
| CN101053392A (en) | Soluble dietary fiber of konjak | |
| CN112691115A (en) | Arabinoxylan and compound for preventing/treating gastrointestinal mucosa and liver injury | |
| CN1287687C (en) | Lead-removing health care food and preparation method thereof | |
| CN101899120A (en) | Method for refining jujube polysaccharide | |
| CN101194684A (en) | Process for preparing soluble edible fibres | |
| CN101496592B (en) | Dietary fiber block and method for processing the same | |
| CN1762222A (en) | Sweet almond oil processed by apricot core with sweet almond and comprehensive utilization of its auxiliary materials | |
| CN105647993A (en) | Production technology of liquid oligogalacturonic acid pectin | |
| CN101941994B (en) | Method for preparing selenium manno-oligosaccharide | |
| CN107793489A (en) | A kind of method that polysaccharide grifolin is extracted from grifola frondosus | |
| CN101797049A (en) | Nutrient eight-treasure soup formula and preparation process thereof | |
| CN1423961A (en) | Chitin healthy food and production thereof | |
| CN1164600C (en) | Process for preparing bifidobacterium factor oligose from gestumor tuber | |
| CN100394923C (en) | Application of low molecular citrus pectin in regulation of blood sugar, blood fat and improvement of fatty liver | |
| Trivedi et al. | Nutraceutical Potential of Marine Macroalgae | |
| CN1817226A (en) | Production of diet fibre with high activity |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |