CN1545995A - Composite of natural plants extract and uses thereof - Google Patents
Composite of natural plants extract and uses thereof Download PDFInfo
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- CN1545995A CN1545995A CNA2003101123867A CN200310112386A CN1545995A CN 1545995 A CN1545995 A CN 1545995A CN A2003101123867 A CNA2003101123867 A CN A2003101123867A CN 200310112386 A CN200310112386 A CN 200310112386A CN 1545995 A CN1545995 A CN 1545995A
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- toothpaste
- radix angelicae
- weight percentage
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- 239000000284 extract Substances 0.000 title claims abstract description 15
- 239000002131 composite material Substances 0.000 title 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 14
- 239000008367 deionised water Substances 0.000 claims abstract description 12
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 12
- 239000000419 plant extract Substances 0.000 claims description 19
- 241000628997 Flos Species 0.000 claims description 17
- 229940034610 toothpaste Drugs 0.000 claims description 16
- 239000000606 toothpaste Substances 0.000 claims description 16
- 230000001976 improved effect Effects 0.000 abstract description 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 241000213006 Angelica dahurica Species 0.000 abstract 1
- 241000205585 Aquilegia canadensis Species 0.000 abstract 1
- 239000001180 angelica archangelica l. root extract Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 239000010634 clove oil Substances 0.000 abstract 1
- 239000001525 mentha piperita l. herb oil Substances 0.000 abstract 1
- 235000019477 peppermint oil Nutrition 0.000 abstract 1
- 238000000034 method Methods 0.000 description 17
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 16
- 241000196324 Embryophyta Species 0.000 description 12
- 239000003795 chemical substances by application Substances 0.000 description 12
- 210000004072 lung Anatomy 0.000 description 11
- 210000002784 stomach Anatomy 0.000 description 9
- 239000000047 product Substances 0.000 description 7
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 6
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- 239000003814 drug Substances 0.000 description 6
- 239000000576 food coloring agent Substances 0.000 description 6
- 239000000600 sorbitol Substances 0.000 description 6
- 239000003995 emulsifying agent Substances 0.000 description 5
- 239000000796 flavoring agent Substances 0.000 description 5
- 235000013355 food flavoring agent Nutrition 0.000 description 5
- 208000007565 gingivitis Diseases 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 201000001245 periodontitis Diseases 0.000 description 5
- 208000004371 toothache Diseases 0.000 description 5
- 206010006326 Breath odour Diseases 0.000 description 4
- 208000032139 Halitosis Diseases 0.000 description 4
- ATUOYWHBWRKTHZ-UHFFFAOYSA-N Propane Chemical compound CCC ATUOYWHBWRKTHZ-UHFFFAOYSA-N 0.000 description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 239000004088 foaming agent Substances 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 238000001256 steam distillation Methods 0.000 description 4
- 239000000080 wetting agent Substances 0.000 description 4
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 230000000202 analgesic effect Effects 0.000 description 3
- 230000000857 drug effect Effects 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 239000002562 thickening agent Substances 0.000 description 3
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 2
- 206010018286 Gingival pain Diseases 0.000 description 2
- 206010018291 Gingival swelling Diseases 0.000 description 2
- 244000246386 Mentha pulegium Species 0.000 description 2
- 235000016257 Mentha pulegium Nutrition 0.000 description 2
- 235000004357 Mentha x piperita Nutrition 0.000 description 2
- 208000025157 Oral disease Diseases 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 2
- 239000003082 abrasive agent Substances 0.000 description 2
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 230000000996 additive effect Effects 0.000 description 2
- 150000001450 anions Chemical class 0.000 description 2
- 230000002421 anti-septic effect Effects 0.000 description 2
- 229920001400 block copolymer Polymers 0.000 description 2
- 239000001768 carboxy methyl cellulose Substances 0.000 description 2
- 239000012141 concentrate Substances 0.000 description 2
- 208000002925 dental caries Diseases 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 230000008030 elimination Effects 0.000 description 2
- 238000003379 elimination reaction Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000012467 final product Substances 0.000 description 2
- 239000003205 fragrance Substances 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 235000001050 hortel pimenta Nutrition 0.000 description 2
- 238000007654 immersion Methods 0.000 description 2
- 230000000968 intestinal effect Effects 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 208000030194 mouth disease Diseases 0.000 description 2
- -1 nonionic Chemical class 0.000 description 2
- FGIUAXJPYTZDNR-UHFFFAOYSA-N potassium nitrate Chemical compound [K+].[O-][N+]([O-])=O FGIUAXJPYTZDNR-UHFFFAOYSA-N 0.000 description 2
- 239000001294 propane Substances 0.000 description 2
- 238000010298 pulverizing process Methods 0.000 description 2
- 239000000377 silicon dioxide Substances 0.000 description 2
- 235000012239 silicon dioxide Nutrition 0.000 description 2
- 230000035943 smell Effects 0.000 description 2
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 2
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 2
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- FTLYMKDSHNWQKD-UHFFFAOYSA-N (2,4,5-trichlorophenyl)boronic acid Chemical compound OB(O)C1=CC(Cl)=C(Cl)C=C1Cl FTLYMKDSHNWQKD-UHFFFAOYSA-N 0.000 description 1
- XGRSAFKZAGGXJV-UHFFFAOYSA-N 3-azaniumyl-3-cyclohexylpropanoate Chemical compound OC(=O)CC(N)C1CCCCC1 XGRSAFKZAGGXJV-UHFFFAOYSA-N 0.000 description 1
- 244000007835 Cyamopsis tetragonoloba Species 0.000 description 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
- 235000019739 Dicalciumphosphate Nutrition 0.000 description 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 1
- 241000276489 Merlangius merlangus Species 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 239000004141 Sodium laurylsulphate Substances 0.000 description 1
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 description 1
- 150000001335 aliphatic alkanes Chemical class 0.000 description 1
- 239000003945 anionic surfactant Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 239000000679 carrageenan Substances 0.000 description 1
- 235000010418 carrageenan Nutrition 0.000 description 1
- 229920001525 carrageenan Polymers 0.000 description 1
- 229940113118 carrageenan Drugs 0.000 description 1
- 230000007012 clinical effect Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 210000003074 dental pulp Anatomy 0.000 description 1
- NEFBYIFKOOEVPA-UHFFFAOYSA-K dicalcium phosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])([O-])=O NEFBYIFKOOEVPA-UHFFFAOYSA-K 0.000 description 1
- 229940038472 dicalcium phosphate Drugs 0.000 description 1
- 229910000390 dicalcium phosphate Inorganic materials 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
- 229940071826 hydroxyethyl cellulose Drugs 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 1
- 210000000214 mouth Anatomy 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 description 1
- 235000010333 potassium nitrate Nutrition 0.000 description 1
- 239000004323 potassium nitrate Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 229940085605 saccharin sodium Drugs 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- KSAVQLQVUXSOCR-UHFFFAOYSA-M sodium lauroyl sarcosinate Chemical compound [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O KSAVQLQVUXSOCR-UHFFFAOYSA-M 0.000 description 1
- 229960004711 sodium monofluorophosphate Drugs 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 229910001631 strontium chloride Inorganic materials 0.000 description 1
- AHBGXTDRMVNFER-UHFFFAOYSA-L strontium dichloride Chemical compound [Cl-].[Cl-].[Sr+2] AHBGXTDRMVNFER-UHFFFAOYSA-L 0.000 description 1
- 150000005846 sugar alcohols Polymers 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 239000012747 synergistic agent Substances 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
Landscapes
- Cosmetics (AREA)
Abstract
The invention relates to a compound of a natural dahurian angelica root extract and its use thereof, wherein the content of the compound includes honeysuckle flower extract 40%-50%, peppermint oil 1%, clove oil 1%-4%, deionized water for the rest. The compound has improved effects and aromatic odor.
Description
Technical field
The present invention relates to a kind of complex of natural plant extracts, the complex that the invention still further relates to this natural plant extracts is applied to field of oral care.
Background technology
According to the Chinese medicine theory, the physiological and pathological of tooth and lung, intestinal, stomach are relevant, and tooth and lung belong to part of the body cavity above the diaphragm housing the heart and lungs position together; The ailment said due to cold or exposure of inside of human body body is invaded outward, the long-pending heat of gastrointestinal can cause that gingival swelling and pain, dry tooth do not moisten, and long-pending heat of lung stomach or stomach have dyspepsia also can produce halitosis, so should select the product of eliminating the pathogens from the lung stomach clearly that dispel the wind for use in oral care product.
Existing oral care product generally adopts toothpaste or collutory, and in these oral care products, be mostly to add the plant extract that certain has effect singlely, and just carry out the specific aim control at oral diseases such as control toothache, gingivitis, periodontitis, halitosis separately, from means is to cure the symptoms, not the disease, and can not realize comprehensive control preferably.
Summary of the invention
The objective of the invention is by multiple natural plants is extracted, thereby form the complex that contains multiple composition, has multiple efficacies.
Another purpose of the present invention is to adopt the complex of above-mentioned natural plant extracts to make toothpaste.
Still a further object of the present invention is to adopt the complex of above-mentioned natural plant extracts to make collutory.
The complex of natural plant extracts of the present invention comprises the Radix Angelicae Dahuricae, Flos Lonicerae, Herba Menthae, four kinds of natural plants of Flos Caryophylli through extracting the spissated complex that forms, and its weight percentage is:
Radix Angelicae Dahuricae extract 40%-55%
Flos Lonicerae extract 40%-50%
Oleum menthae 1%
Oleum Caryophylli 1%-4%
The deionized water surplus
The toothpaste that adopts the complex of above-mentioned natural plant extracts to make, its toothpaste contains the complex that weight percentage is the 8%-10% natural plant extracts.
The collutory that adopts the complex of above-mentioned natural plant extracts to make, its collutory contains the complex that weight percentage is the 4%-5% natural plant extracts.
The complex of the natural plant extracts that the present invention adopts, be to utilize Chinese traditional medicine principle, start with from the basic reason that produces tooth pain, gingivitis, periodontitis, halitosis, the complex of selected plant extract can be gone into the warp of lung, stomach, intestinal, by dispelling wind evil, rush down stomach-fire, separate the purpose that lung-heat reaches control toothache, gingivitis, periodontitis.
The drug effect of four contained kind of plant is in the complex of the present invention:
The Radix Angelicae Dahuricae, its drug effect suffering can loose wind, temperature can dampness, goes into lung stomach two warps, kind ailment said due to cold or exposure of separating lung stomach two warp can control that superciliary ridge leads to, gingival swelling and pain etc.; In the application of the treasure " Chinese medicine " of the Chinese nation, prescriptions of Chinese medicine at all times all the Radix Angelicae Dahuricae as the most effective Chinese medicine in analgesic, good clinical effect and long applicating history are arranged; Its extracting method is: with the distilled water immersion of Radix Angelicae Dahuricae pulverizing back with 10 times, heating decocts back elimination medicinal residues, obtains initial concentration liquid, adds ethanol in this initial concentration liquid, distilling under reduced pressure is also reclaimed ethanol, and the final concentrated solution that can obtain active matter content and be 7-10% gets final product.Also can adopt additive method to extract.
Flos Lonicerae has stronger heat-clearing toxin-expelling functions, can go into lung stomach heart spleen four warps, energy heat-clearing and toxic substances removing, reducing swelling and alleviating pain; The extracting method of Flos Lonicerae and said extracted method are mutually roughly the same.
Oleum Caryophylli is to extract from the Flos Caryophylli plant, its effect is gone into stomach, spleen, kidney three warps, be that a kind of fragrance ingredient has bactericidal action again, be exposed to toothache patient in the oral cavity to suffering from dark dental caries of tooth and dental pulp nerve, Oleum Caryophylli can play the analgesic effect immediately; The extracting method of Oleum Caryophylli can obtain with dry flower flower bud or the bennet that steam distillation distills the fourth pole.
Herba Menthae can go into lung, liver two warps, the hot part of the body cavity above the diaphragm housing the heart and lungs ailment said due to cold or exposure of loosing, cool can heat clearing away, have the effect of anti-inflammatory analgetic; The Oleum menthae that extracts can distill peppermint stem and leaf with steam distillation and obtain.
Above-mentioned four kind of plant extracts are after mixing, form complex, not only improved drug effect greatly, and extract has the abnormal smells from the patient of fragrance, the no special abnormal smells from the patient that is difficult to hide, each component all has the bacteriostatic effect on pharmacology, complex can extensively play significant nursing efficacy at oral diseases such as toothache, gingivitis, periodontitis, dental caries, halitosis.
Adopt product that complex of the present invention makes through clinical verification, to the effective percentage of gingivitis and periodontitis and obvious effective rate all more than 87%.
Complex of the present invention adopts extracted form natural plant, concentrates, proportioning and forming, and can also adopt traditional Chinese medicine extraction, concentrates, matching method, and the complex of making is convenient to store, dosage is used.
Adopt complex of the present invention to can be made into oral care product, as toothpaste, collutory etc.
The specific embodiment
A kind of natural plants complex comprises that the Radix Angelicae Dahuricae, Flos Lonicerae, Herba Menthae, four kinds of natural plants of Flos Caryophylli form the complex of spissated natural plant extracts after extracting, and its weight percentage is:
Radix Angelicae Dahuricae extract 40%-55%
Flos Lonicerae extract 40%-50%
Oleum menthae 1%
Oleum Caryophylli 1%-4%
The deionized water surplus
The complex of described natural plant extracts, its best weight percentage are (total amount 100%):
Radix Angelicae Dahuricae extract 48%
Flos Lonicerae extract 42%
Oleum menthae 1%
Oleum Caryophylli 2%
Deionized water 7%
The extracting method of the above-mentioned Radix Angelicae Dahuricae, Flos Lonicerae is: with the distilled water immersion of above-mentioned material pulverizing back with 10 times, heating decocts back elimination medicinal residues, obtain initial concentration liquid, in this initial concentration liquid, add ethanol, distilling under reduced pressure is also reclaimed ethanol, and the final concentrated solution that can obtain active matter content and be 7-10% gets final product.
The extracting method of Oleum Caryophylli can obtain with dry flower flower bud or the bennet that steam distillation distills the fourth pole.
The extracting method of Oleum menthae can distill peppermint stem and leaf with steam distillation and obtain.
Above-mentioned described extracting method also can adopt additive method to extract.
Adopt the complex of above-mentioned natural plant extracts to make a kind of toothpaste, its weight percentage is:
Abrasivus 45%-50% essence 1.0%-1.4%
Wetting agent 20%-30% sweeting agent 0.2%-0.3%
Foaming agent 1.5%-2.0% antiseptic 0.2%-0.4%
Thickening agent 1.0%-1.4% buffer agent 0.1%-0.5%
The complex 8%-10% food coloring of natural plants is an amount of
Deionized water: surplus
In the toothpaste component:
Abrasive is: meet natural stone-powder, dicalcium phosphate dehydrate, silicon dioxide of toothpaste industry standard etc.;
Wetting agent is: sorbitol (70%), glycerol, xylitol, propylene glycol etc. can be used for the polyhydric alcohol of toothpaste;
Foaming agent is: nontoxic materials such as anion, nonionic, anion and non-ionic mixture, and foaming agent is to produce foamy surfactant, as: sodium lauryl sulfate, potassium salt etc.;
Thickening agent is: sodium carboxymethyl cellulose, HANSHENGJIAO, modified guar, carrageenan, hydroxyethyl-cellulose etc.;
Also can add flavouring agent, sweeting agent, antiseptic, buffer agent, food coloring, deionized water in the component and some can increase the material of toothpaste feature.
Also can add effect materials such as sodium monofluorophosphate, sodium chloride, strontium chloride, potassium nitrate in the toothpaste combination.
Embodiment: toothpaste of the present invention adopts the dry method one-step method to make, and weight is percentage composition (100 parts of total amounts) in its partition:
45 parts of abrasives (natural whiting)
10 parts of wetting agents (sorbitol)
15 parts of wetting agents (glycerol)
1.0 parts of thickening agents (sodium carboxymethyl cellulose)
4 parts of abrasives (silicon dioxide)
1.8 parts of foaming agent (sodium lauryl sulphate)
0.1 part of buffer agent
0.2 part of sweeting agent (saccharin sodium)
1.2 parts of flavouring agents (edible essence)
10 parts of the complex of natural plants
Food coloring is an amount of
The deionized water surplus
The making of above-mentioned toothpaste is available rows other technologies commonly used in the industry also, make as methods such as two-step method, wet method one-step method.
The collutory that adopts natural plants complex of the present invention to make, its weight percentage is:
Ethanol 10%-15% essence 0.4%-0.8%
The complex 4%-5% of sorbitol 15%-25% natural plants
Emulsifying agent 1%-3% sweeting agent 0.1%-0.2%
Buffer agent 0.1%-0.2% food coloring is an amount of
The deionized water surplus
Above-mentioned described ethanol is a kind of synergistic agent and solvent; After adding sorbitol, make the mouthfeel of collutory better; The emulsifying agent that adds can for: tween, anion surfactant as the block copolymer of sodium lauroyl sarcosine, oxirane and expoxy propane etc.; Emulsifying agent can make collutory be unlikely to too thin in use but can produce a little foam, thereby has improved the performance of using greatly; Need to add suitable flavouring agent, sweeting agent, buffer agent, food coloring etc. simultaneously.
Embodiment: collutory of the present invention, its prescription is weight percentage (100 parts of gross weights):
10 parts of ethanol
15 parts of sorbitol
1 part of emulsifying agent (block copolymer of oxirane and expoxy propane base alkane)
0.6 part of flavouring agent (edible essence)
0.2 part of sweeting agent (edible glucide)
5 parts of the complex of natural plants
0.1 part of buffer agent
Food coloring is an amount of
The deionized water surplus
The production method of collutory can be a conventional method, embodiment: after mixing of materials stirring and dissolving such as emulsifying agent and ethanol, flavouring agent, slowly add deionized water, sorbitol etc., stir till solution is transparent, leaving standstill promptly can packed products after the cooling.
Claims (6)
1, a kind of complex of natural plant extracts is characterized in that: described complex forms concentrated solution by the natural Radix Angelicae Dahuricae, Flos Lonicerae, Herba Menthae, Flos Caryophylli four kind of plant through extracting, and its weight percentage is:
Radix Angelicae Dahuricae extract 40%-55%
Flos Lonicerae extract 40%-50%
Oleum menthae 1%
Oleum Caryophylli 1%-4%
The deionized water surplus
2, the complex of a kind of natural plant extracts according to claim 1 is characterized in that: the described complex of forming by the Radix Angelicae Dahuricae, Flos Lonicerae, Herba Menthae, Flos Caryophylli extract, and its weight percentage is:
Radix Angelicae Dahuricae extract 48%
Flos Lonicerae extract 42%
Oleum menthae 1%
Oleum Caryophylli 2%
Deionized water 7%
3, a kind of toothpaste is the application that claim 1 or 2 described complex are used to prepare toothpaste.
4, a kind of toothpaste according to claim 3 is characterized in that: described complex weight percentage is 8%-10%.
5, a kind of collutory is the application that claim 1 or 2 described complex are used to prepare collutory.
6, a kind of collutory according to claim 5 is characterized in that: described complex weight percentage is: 4%-5%.
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CN 200310112386 CN1259899C (en) | 2003-11-28 | 2003-11-28 | Composite of natural plants extract and uses thereof |
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CN 200310112386 CN1259899C (en) | 2003-11-28 | 2003-11-28 | Composite of natural plants extract and uses thereof |
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CN1545995A true CN1545995A (en) | 2004-11-17 |
CN1259899C CN1259899C (en) | 2006-06-21 |
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CN102274139A (en) * | 2011-01-14 | 2011-12-14 | 哈药集团三精制药股份有限公司 | Chinese medicinal (honeysuckle, baikal skullcap root and forsythia) toothpaste and preparation method thereof |
CN104095929A (en) * | 2014-07-29 | 2014-10-15 | 桂林实力科技有限公司 | Decayed-tooth-resistant chewing gum |
CN104523514A (en) * | 2014-12-18 | 2015-04-22 | 东莞市阿比亚能源科技有限公司 | Tooth washing liquid |
CN104721314A (en) * | 2015-04-07 | 2015-06-24 | 范永启 | Aromatherapy gargle compound essential oil |
CN107714546A (en) * | 2017-11-02 | 2018-02-23 | 广州丽丰化妆品制造有限公司 | A kind of toothpaste and its production method for suppressing helicobacter pylori in oral cavity |
CN108434257A (en) * | 2018-05-23 | 2018-08-24 | 李百峻 | Medical floride-free antibacterial mouthwash of one kind and preparation method thereof |
CN109528928A (en) * | 2019-01-14 | 2019-03-29 | 王晶 | The Chinese medicine composition and pharmaceutical preparation and application and application method for treating diabetic keratopathy periodontitis |
CN109758403A (en) * | 2019-03-29 | 2019-05-17 | 上海涵博生物科技有限公司 | One kind is quick-acting to control toothache by spraying |
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2003
- 2003-11-28 CN CN 200310112386 patent/CN1259899C/en not_active Expired - Lifetime
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CN104095929A (en) * | 2014-07-29 | 2014-10-15 | 桂林实力科技有限公司 | Decayed-tooth-resistant chewing gum |
CN104095929B (en) * | 2014-07-29 | 2016-06-22 | 桂林实力科技有限公司 | Dental caries chewing gum |
CN104523514A (en) * | 2014-12-18 | 2015-04-22 | 东莞市阿比亚能源科技有限公司 | Tooth washing liquid |
CN104721314A (en) * | 2015-04-07 | 2015-06-24 | 范永启 | Aromatherapy gargle compound essential oil |
CN107714546A (en) * | 2017-11-02 | 2018-02-23 | 广州丽丰化妆品制造有限公司 | A kind of toothpaste and its production method for suppressing helicobacter pylori in oral cavity |
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CN109528928A (en) * | 2019-01-14 | 2019-03-29 | 王晶 | The Chinese medicine composition and pharmaceutical preparation and application and application method for treating diabetic keratopathy periodontitis |
CN109758403A (en) * | 2019-03-29 | 2019-05-17 | 上海涵博生物科技有限公司 | One kind is quick-acting to control toothache by spraying |
CN112891464A (en) * | 2021-01-19 | 2021-06-04 | 李智民 | External-use pharmaceutical composition for swelling and aching of gum and oral bacteriostasis and preparation method thereof |
CN115531274A (en) * | 2022-11-04 | 2022-12-30 | 深圳逗点生物技术有限公司 | Pure plant antibacterial gargle and preparation method thereof |
CN115887582A (en) * | 2023-01-05 | 2023-04-04 | 文德志 | Aromatic turbid-removing traditional Chinese medicine mouthwash |
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