CN1526448A - 用于治疗肛门直肠病的药物和方法 - Google Patents

用于治疗肛门直肠病的药物和方法 Download PDF

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Publication number
CN1526448A
CN1526448A CNA200410008292XA CN200410008292A CN1526448A CN 1526448 A CN1526448 A CN 1526448A CN A200410008292X A CNA200410008292X A CN A200410008292XA CN 200410008292 A CN200410008292 A CN 200410008292A CN 1526448 A CN1526448 A CN 1526448A
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CN
China
Prior art keywords
medicine
disease
purposes
anal
atp
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Pending
Application number
CNA200410008292XA
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English (en)
Chinese (zh)
Inventor
T��P���޶���
T·P·帕克斯
V·马克
J·C·李
C·李
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DMK Pharmaceuticals Corp
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Cellegy Pharmaceuticals Inc
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27381146&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1526448(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cellegy Pharmaceuticals Inc filed Critical Cellegy Pharmaceuticals Inc
Publication of CN1526448A publication Critical patent/CN1526448A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CNA200410008292XA 1998-12-14 1999-12-13 用于治疗肛门直肠病的药物和方法 Pending CN1526448A (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US11232598P 1998-12-14 1998-12-14
US60/112,325 1998-12-14
US13991699P 1999-06-17 1999-06-17
US60/139,916 1999-06-17
US60/155,318 1999-09-12
US15531899P 1999-09-21 1999-09-21

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CNB998144304A Division CN1149983C (zh) 1998-12-14 1999-12-13 用于治疗肛门直肠病的组合物和方法

Publications (1)

Publication Number Publication Date
CN1526448A true CN1526448A (zh) 2004-09-08

Family

ID=27381146

Family Applications (2)

Application Number Title Priority Date Filing Date
CNA200410008292XA Pending CN1526448A (zh) 1998-12-14 1999-12-13 用于治疗肛门直肠病的药物和方法
CNB998144304A Expired - Fee Related CN1149983C (zh) 1998-12-14 1999-12-13 用于治疗肛门直肠病的组合物和方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CNB998144304A Expired - Fee Related CN1149983C (zh) 1998-12-14 1999-12-13 用于治疗肛门直肠病的组合物和方法

Country Status (14)

Country Link
US (2) US6395736B1 (enExample)
EP (1) EP1143956A3 (enExample)
JP (1) JP2002542147A (enExample)
KR (1) KR20010093828A (enExample)
CN (2) CN1526448A (enExample)
AU (1) AU764921B2 (enExample)
BR (1) BR9916162A (enExample)
CA (1) CA2354543A1 (enExample)
CZ (1) CZ20012113A3 (enExample)
HU (1) HUP0104676A3 (enExample)
IL (1) IL143726A0 (enExample)
NO (1) NO20012916L (enExample)
PL (1) PL348817A1 (enExample)
WO (1) WO2000035434A2 (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103393690A (zh) * 2013-08-01 2013-11-20 南通大学附属医院 Katp通道开放剂在制备治疗术后疼痛药物中的应用
CN101868239B (zh) * 2006-01-05 2015-06-10 伊森舍丽斯有限公司 钾atp通道开放剂的盐及其用途
CN112423736A (zh) * 2018-06-01 2021-02-26 塔凡塔医疗匈牙利公司 用于治疗肛门直肠疾病的局部氨氯地平盐

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HRP20020751B1 (hr) 2000-02-15 2011-01-31 Sugen Pirolom supstituirani 2-indolinoni kao inhibitori protein kinaze
MXPA03000931A (es) * 2000-07-31 2004-08-12 Cellegy Pharma Inc Composiciones y metodos para el tratamientos de trastornos anorectales.
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AR042586A1 (es) * 2001-02-15 2005-06-29 Sugen Inc 3-(4-amidopirrol-2-ilmetiliden)-2-indolinona como inhibidores de la protein quinasa; sus composiciones farmaceuticas; un metodo para la modulacion de la actividad catalitica de la proteinquinasa; un metodo para tratar o prevenir una afeccion relacionada con la proteinquinasa
DE10118305A1 (de) * 2001-04-12 2002-10-17 Bayer Ag Zusammensetzungen zur nasalen Applikation
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JP2005508953A (ja) 2001-10-10 2005-04-07 スージェン・インコーポレーテッド キナーゼ阻害剤としての3−[4−(置換ヘテロサイクリル)−ピロール−2−イルメチリデン]−2−インドリノン誘導体
JP4563679B2 (ja) * 2001-12-06 2010-10-13 デューク ユニバーシティ 形成外科における組織弁壊死の予防
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DE10352132A1 (de) * 2003-11-04 2005-06-09 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmazeutische Zusammensetzung aus einem Beta-3-Adrenozeptor-Agonisten und einem Alpha Agonisten
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US20080045534A1 (en) * 2006-08-18 2008-02-21 Valeant Pharmaceuticals North America Derivatives of 1,3-diamino benzene as potassium channel modulators
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CA3155812A1 (en) 2019-11-08 2021-05-14 Cynthia Louise HARDEN Methods of treating depressive disorders
TW202245744A (zh) 2021-02-09 2022-12-01 加拿大商再諾製藥公司 治療失樂症之方法及用途

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101868239B (zh) * 2006-01-05 2015-06-10 伊森舍丽斯有限公司 钾atp通道开放剂的盐及其用途
CN103393690A (zh) * 2013-08-01 2013-11-20 南通大学附属医院 Katp通道开放剂在制备治疗术后疼痛药物中的应用
CN103393690B (zh) * 2013-08-01 2016-05-11 南通大学附属医院 Katp通道开放剂在制备治疗术后疼痛药物中的应用
CN112423736A (zh) * 2018-06-01 2021-02-26 塔凡塔医疗匈牙利公司 用于治疗肛门直肠疾病的局部氨氯地平盐

Also Published As

Publication number Publication date
PL348817A1 (en) 2002-06-17
CN1149983C (zh) 2004-05-19
NO20012916L (no) 2001-08-14
WO2000035434A3 (en) 2000-11-30
US6395736B1 (en) 2002-05-28
NO20012916D0 (no) 2001-06-13
JP2002542147A (ja) 2002-12-10
US20010012856A1 (en) 2001-08-09
CA2354543A1 (en) 2000-06-22
CZ20012113A3 (cs) 2001-11-14
HUP0104676A2 (en) 2002-06-29
AU2176300A (en) 2000-07-03
AU764921B2 (en) 2003-09-04
KR20010093828A (ko) 2001-10-29
EP1143956A2 (en) 2001-10-17
HUP0104676A3 (en) 2005-12-28
WO2000035434A2 (en) 2000-06-22
EP1143956A3 (en) 2001-12-12
IL143726A0 (en) 2002-04-21
BR9916162A (pt) 2001-09-04
CN1330539A (zh) 2002-01-09

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