CN1524542A - Medicament for treating acute and chronic rhinitis and nasosinusitis - Google Patents
Medicament for treating acute and chronic rhinitis and nasosinusitis Download PDFInfo
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- CN1524542A CN1524542A CNA031052150A CN03105215A CN1524542A CN 1524542 A CN1524542 A CN 1524542A CN A031052150 A CNA031052150 A CN A031052150A CN 03105215 A CN03105215 A CN 03105215A CN 1524542 A CN1524542 A CN 1524542A
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Abstract
The invention discloses a medicament for treating acute and chronic rhinitis and auxiliary nasal sinusitis, in particular a prepared Chinese herbal preparation whose raw materials includes magnolia flower, Xanthium sibiricum, dahurian angelica root, ledebouriella root, licorice root, notopterygium root, asaryl, Ligusticum wallichii, chrysanthemum flower, baikal skullcap root, isatic root, cordate houttuynia, couch grass root, radix rubiae, bletilla striata, ricepaper pith, sweetgum fruit, astragalus root, pilose asiabell root.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of acute and chronic rhinitis and sinusitis, especially a kind of is the Chinese patent medicine of feedstock production with the Chinese herbal medicine.
Background technology
Up to the present, the radical cure to rhinitis still is difficult clinically, also without any specific drugs.Particularly, the medicine of Western medicine therapeutic alliance acute and chronic rhinitis and sinusitis, have the bad or side effect significant disadvantages of curative effect.
Summary of the invention
The purpose of this invention is to provide a kind of medicine for the treatment of acute and chronic rhinitis and passing sinusitis, especially providing a kind of is the Chinese patent medicine of feedstock production with the Chinese herbal medicine.It has overcome the shortcoming that present clinical treatment acute and chronic rhinitis and sinusitis can not be effected a radical cure.
Solution of the present invention is based on understanding and the Therapeutic Principle of motherland's medical science to treatment acute and chronic rhinitis and sinusitis pathogenic mechanism, achieve with reference to modern pharmacological research, from motherland medicine treasure-house, the natural plant that filters out is by monarch, the minister of the traditional Chinese medical science, help, make principle to carry out prescription.
The present invention is achieved by the following technical solutions:
The medicament that drug main of the present invention will be made by the following weight parts raw material: Flos Magnoliae 10-20, Herba Xanthii 15-25, Radix Angelicae Dahuricae 5-15, Radix Saposhnikoviae 5-15, Radix Glycyrrhizae 4-8; Optimum ratio is: Flos Magnoliae 15, Herba Xanthii 12, the Radix Angelicae Dahuricae 10, Radix Saposhnikoviae 10, Radix Glycyrrhizae 6.
For reaching the disease for the treatment of described acute and chronic rhinitis and sinusitis and following headache, described medicament can add Rhizoma Et Radix Notopterygii 5-10, Herba Asari 8-10, Rhizoma Chuanxiong 8-10.
For reaching treatment described acute and chronic rhinitis and sinusitis and following the dense condensed disease of nasal mucus, described medicament can add Radix Scutellariae 10-15, connect and call 6-10, Radix Isatidis 10-15, Herba Houttuyniae 6-10 together.
For reaching the disease for the treatment of described acute and chronic rhinitis and sinusitis and following the blood streak, described medicament can add Rhizoma Imperatae 5-10, Radix Rubiae 5-12, Pseudobulbus Bletillae (Rhizoma Bletillae) 10-12.
For reaching treatment described acute and chronic rhinitis and sinusitis and following the obstructed disease of nasal obstruction, described medicament can add Medulla Tetrapanacis 6-8, Fructus Liquidambaris or acupuncture fragrant cave 10-15.
For reaching the disease of the described acute and chronic rhinitis of treatment and sinusitis and weakness due to chronic disease, described medicament can add Radix Astragali 8-10, Radix Codonopsis 6-8.
Described medicament is the preparation on any pharmaceutics, especially tablet, clothes wafer, solution.
The preparation method of medicine of the present invention is that the Chinese medicine preparation method prepares routinely: the employing water alcohol method extracts, and above-mentioned each raw material arrangement is cleaned, and the decoction of heating, filtration, concentrated, ethanol extraction recovery concentrate, and make various dosage forms according to the different dosage form method for making then.
Clinical drug of the present invention uses the result to show to have following advantage:
1, to select natural drug for use be raw material in the present invention, and each component meets the pharmaceutical control law regulation.Utilize the comprehensive function treatment coryza of the Chinese medicine of respectively distinguishing the flavor of, human body is had no side effect.
2, after the present invention is prepared into various preparations, take more convenient, safety; Steady quality, determined curative effect.
3, crude drug of the present invention is originated and is easy to get, and has significantly reduced cost.
For showing the effect of medicine of the present invention to treatment acute and chronic rhinitis and sinusitis, from year December in January to 2000 nineteen ninety, all kinds of rhinitis are carried out 257 routine cases investigate and diagnosis and treatment, wherein M-F is 5: 1, age 20-65 year.And be contrast not take medicine of the present invention, select clinic case, medicine of the present invention has been carried out nearly 10 years investigation shown, the patient that takes medicine all there is good efficacy.
Instructions of taking: every day potion, took for one to three week continuously, treat clinical symptom disappearance after, add commercially available LIUWEI DIHUANG WAN, took continuously three to six months, to consolidate curative effect.Irritable foods such as period in a medicine diet, life, cold, greasy, fish raw meat, pungent drinks, and alleviating alcohol addiction.
The 257 routine patients that receive treatment, strictness is followed the doctor's advice, and cure rate is 100%, and relapse rate is low, does not guard against tobacco and wine and recurring, does not have recurrent cases except that individual patient, and therapeutic effect is good, does not see toxic and side effects.It is capsule, tablet or solution nose potus that the case of accepting to investigate is taken pharmaceutical dosage form of the present invention respectively.
Some cases patient clinical efficacy is as mentioned below.
1, the nineteen ninety-nineteen ninety-five the some cases curative effect investigated.
Li Shuzhen, the woman 31 years old, played the trouble chronic sinusitis, i.e. recurrence after chance Changes in weather or the flu, obstinate to 22 years old.After taking the agent of this Drug Capsule, the recovery from illness of three weeks, not recurrence so far.
Liu Shu, the man, 45 years old, suffer from acute rhinitis and also accompany headache, rhinorrhea, nasal obstruction, take this drug solns nose potus after, disease disappeared in 1 week, added 1 week of LIUWEI DIHUANG WAN, to consolidate curative effect, not recurrence so far.
Zhang Yueming, the woman, 25 years old, suffer from chronic rhinitis, and companion's blood streak, giddy, rhinorrhea, the snuffles state, take this tablet after, 2 all Signs disappear, so far recurrence.
2, the some cases curative effect of 1995-2000 investigation.
Zhou Feng, man, 66 years old.Suffered from chronic sinusitis 12 years, and took three weeks of this medicine nose potus, disease disappears, and adds LIUWEI DIHUANG WAN two months, so far not recurrence.
Zhang Hongmei, woman 45 years old.The acute rhinitis and the wake nasal mucus of catching a cold and causing, nasal obstruction, take this medicine nose potus after, 1 all disease disappears.
The specific embodiment
Embodiment 1:
Take by weighing raw material (kilogram) by following proportioning: Flos Magnoliae 15, Herba Xanthii 12, the Radix Angelicae Dahuricae 10, Radix Saposhnikoviae 10, Radix Glycyrrhizae 6, Rhizoma Et Radix Notopterygii 8, Herba Asari 9, Rhizoma Chuanxiong 9.
Method for making: above-mentioned raw materials is decocted with water secondary (1.5,1 hours), merge decoction liquor, use micro-pore-film filtration, aperture 1.2 μ m, filtered solution is concentrated into 400ml, add ethanol, making concentration of alcohol is 60% of concentrated solution, leaves standstill 48 hours, the liquid that disappears in the absorption reclaims ethanol and makes medicinal liquid not have the ethanol flavor, is concentrated into 400ml, adding distil water is to 1000ml, embedding with 100 ℃ of 20 minutes flowing steam sterilizations, gets solution nose potus in 10ml solution bottle.
Embodiment 2:
Take by weighing raw material (kilogram) by following proportioning: Flos Magnoliae 20, Herba Xanthii 25, the Radix Angelicae Dahuricae 15, Radix Saposhnikoviae 15, Radix Glycyrrhizae 8, Flos Chrysanthemi 15, disease multitude 10.
Method for making: make concentrated solution by embodiment 1 method earlier, continue to concentrate, granulate with 60% concentration ethanol, drying, reuse 100 μ m sieve granulate, and selecting cellulose acetate-phthalate (CAP) for use is the capsule material, makes capsule.
Embodiment 3:
Take by weighing raw material (kilogram) by following proportioning: Flos Magnoliae 10, Herba Xanthii 15, the Radix Angelicae Dahuricae 5, Radix Saposhnikoviae 5, Radix Glycyrrhizae 6, Radix Scutellariae 10 connects and calls 6 together, Radix Isatidis 10, Herba Houttuyniae 6.
Method for making: make concentrated solution by the embodiment method earlier, continue to concentrate, granulate with 70% concentration ethanol, drying, reuse 200 μ m sieve granulate, and with granule and magnesium stearate 2g mix homogeneously, the tablet machine tabletting can make tablet.
Embodiment 4:
Take by weighing raw material (kilogram) by following proportioning: Flos Magnoliae 15, Herba Xanthii 12, the Radix Angelicae Dahuricae 10, Radix Saposhnikoviae 10, Radix Glycyrrhizae 6, Rhizoma Imperatae 6, Radix Rubiae 10, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10, Medulla Tetrapanacis 6, Fructus Liquidambaris 10, the Radix Astragali 9, Radix Codonopsis 7.
Method for making: make nose drink solution by embodiment 1 method.
Claims (10)
1, a kind of medicine for the treatment of acute and chronic rhinitis and sinusitis is the medicament that comprises that following parts by weight of component is formulated: Flos Magnoliae 10-20, Herba Xanthii 15-25, Radix Angelicae Dahuricae 5-15, Radix Saposhnikoviae 5-15, Radix Glycyrrhizae 4-8.
2, the medicine of treatment acute and chronic rhinitis according to claim 1 and sinusitis, the weight proportion of described each component of medicament is: Flos Magnoliae 15, Herba Xanthii 12, the Radix Angelicae Dahuricae 10, Radix Saposhnikoviae 10, Radix Glycyrrhizae 6.
3, the medicine of treatment acute and chronic rhinitis according to claim 1 and sinusitis, described medicament can also contain the following weight parts component: Rhizoma Et Radix Notopterygii 5-10, Herba Asari 8-10, Rhizoma Chuanxiong 8-10.
4, the medicine of treatment acute and chronic rhinitis according to claim 1 and sinusitis, described medicament can also contain the following weight parts component: Flos Chrysanthemi 10-15, disease multitude 6-10.
5, the medicine of treatment acute and chronic rhinitis according to claim 1 and sinusitis, described medicament can also contain the following weight parts component: Radix Scutellariae 10-15 connects and calls 6-10 together, Radix Isatidis 10-15, Herba Houttuyniae 6-10.
6, the medicine of treatment acute and chronic rhinitis according to claim 1 and sinusitis, described medicament can also contain the following weight parts component: Rhizoma Imperatae 5-10, Radix Rubiae 5-12, Pseudobulbus Bletillae (Rhizoma Bletillae) 10-12.
7, the medicine of treatment acute and chronic rhinitis according to claim 1 and sinusitis, described medicament can also contain the following weight parts component: Medulla Tetrapanacis 6-8, Fructus Liquidambaris or acupuncture fragrant cave 10-15.
8, the medicine of treatment acute and chronic rhinitis according to claim 1 and sinusitis, described medicament can also contain the following weight parts component: Radix Astragali 8-10, Radix Codonopsis 6-8.
9, according to the treatment acute and chronic rhinitis of one of claim 1-9 and the medicine of sinusitis, described medicament is the preparation on any pharmaceutics.
10, according to the treatment acute and chronic rhinitis and the sinusitis medicine of claim 9, described medicament is tablet, clothes wafer, solution nose potus.
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CN 03105215 CN1256956C (en) | 2003-02-24 | 2003-02-24 | Medicament for treating acute and chronic rhinitis and nasosinusitis |
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CN 03105215 CN1256956C (en) | 2003-02-24 | 2003-02-24 | Medicament for treating acute and chronic rhinitis and nasosinusitis |
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CN101069706B (en) * | 2006-05-08 | 2010-05-12 | 乔德荣 | Medicine for treating sinusitis |
CN101024008B (en) * | 2007-04-05 | 2010-09-08 | 张喜凤 | Oral Chinese medicine composition for treating sinusitis |
CN101007083B (en) * | 2006-01-26 | 2010-12-29 | 重庆大易科技投资有限公司 | Medicine composition for treating acute and chronic rhinitis or sinusitis and its preparation method |
CN101181415B (en) * | 2007-11-26 | 2011-08-10 | 张云霞 | Chinese medicine decoction for curing chronic sinusitis |
CN101204479B (en) * | 2007-12-13 | 2011-11-16 | 张益军 | Chinese traditional medicine preparation for acute sinusitis |
CN102846954A (en) * | 2012-08-31 | 2013-01-02 | 霍山县中医院 | Chinese herbal pill for treating nasosinusitis by using xanthium |
CN103239532A (en) * | 2013-04-24 | 2013-08-14 | 王永红 | Medicament for treating chronic pharyngitis and preparation method thereof |
CN104187684A (en) * | 2014-09-25 | 2014-12-10 | 洛阳华以生物工程有限公司 | Food therapy formula for chronic simple rhinitis |
CN104474104A (en) * | 2014-11-26 | 2015-04-01 | 郑州后羿制药有限公司 | Traditional Chinese medicine composition for preventing and treating infectious rhinitis of chicken and preparation method thereof |
CN104490989A (en) * | 2014-11-27 | 2015-04-08 | 蒙毅嘉 | Traditional Chinese medicine composition for treating nasosinusitis |
CN104547659A (en) * | 2014-09-30 | 2015-04-29 | 潘景山 | Drop for treatment of rhinitis and preparation method of drop |
CN104971222A (en) * | 2015-06-12 | 2015-10-14 | 陈文滨 | Traditional Chinese medicine external preparation for treating rhinitis and its preparation method and use |
CN105012484A (en) * | 2015-07-20 | 2015-11-04 | 重庆市永川区中医院 | Pharmaceutical preparation for treatment of purulent sinusitis and preparation method thereof |
CN105311144A (en) * | 2015-11-28 | 2016-02-10 | 史克勇 | Compound preparation containing rhizoma cimicifugae |
CN106309974A (en) * | 2016-08-29 | 2017-01-11 | 杨程凯 | Traditional chinese medicine composition |
CN106727927A (en) * | 2016-12-12 | 2017-05-31 | 湖北中医药大学 | Rhinitis chronic chewing gum |
CN108186734A (en) * | 2018-03-13 | 2018-06-22 | 青岛大学附属医院 | A kind of rhinitis clinic externally applied drug and preparation method thereof |
CN111184770A (en) * | 2020-02-12 | 2020-05-22 | 常德集智生物科技有限公司 | Green rhinitis relieving lotion |
CN116983350A (en) * | 2023-09-19 | 2023-11-03 | 湖南中医药大学第一附属医院(中医临床研究所) | Traditional Chinese medicine composition for treating allergic rhinitis, preparation method and application |
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2003
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CN101007083B (en) * | 2006-01-26 | 2010-12-29 | 重庆大易科技投资有限公司 | Medicine composition for treating acute and chronic rhinitis or sinusitis and its preparation method |
CN101069706B (en) * | 2006-05-08 | 2010-05-12 | 乔德荣 | Medicine for treating sinusitis |
CN101024008B (en) * | 2007-04-05 | 2010-09-08 | 张喜凤 | Oral Chinese medicine composition for treating sinusitis |
CN101181415B (en) * | 2007-11-26 | 2011-08-10 | 张云霞 | Chinese medicine decoction for curing chronic sinusitis |
CN101204479B (en) * | 2007-12-13 | 2011-11-16 | 张益军 | Chinese traditional medicine preparation for acute sinusitis |
CN102846954A (en) * | 2012-08-31 | 2013-01-02 | 霍山县中医院 | Chinese herbal pill for treating nasosinusitis by using xanthium |
CN102846954B (en) * | 2012-08-31 | 2014-02-05 | 霍山县中医院 | Traditional Chinese medicine pill for treating chronic rhinitis and chronic nasosinusitis by using xanthium |
CN103239532A (en) * | 2013-04-24 | 2013-08-14 | 王永红 | Medicament for treating chronic pharyngitis and preparation method thereof |
CN104187684A (en) * | 2014-09-25 | 2014-12-10 | 洛阳华以生物工程有限公司 | Food therapy formula for chronic simple rhinitis |
CN104547659A (en) * | 2014-09-30 | 2015-04-29 | 潘景山 | Drop for treatment of rhinitis and preparation method of drop |
CN104474104B (en) * | 2014-11-26 | 2017-11-14 | 河南后羿实业集团有限公司 | A kind of Chinese medicine composition for preventing and treating infectious coryza of chicken and preparation method thereof |
CN104474104A (en) * | 2014-11-26 | 2015-04-01 | 郑州后羿制药有限公司 | Traditional Chinese medicine composition for preventing and treating infectious rhinitis of chicken and preparation method thereof |
CN104490989A (en) * | 2014-11-27 | 2015-04-08 | 蒙毅嘉 | Traditional Chinese medicine composition for treating nasosinusitis |
CN104971222A (en) * | 2015-06-12 | 2015-10-14 | 陈文滨 | Traditional Chinese medicine external preparation for treating rhinitis and its preparation method and use |
CN104971222B (en) * | 2015-06-12 | 2018-11-06 | 陈文滨 | A kind of Chinese medicine for treating rhinitis external preparation and the preparation method and application thereof |
CN105012484A (en) * | 2015-07-20 | 2015-11-04 | 重庆市永川区中医院 | Pharmaceutical preparation for treatment of purulent sinusitis and preparation method thereof |
CN105012484B (en) * | 2015-07-20 | 2018-08-14 | 重庆市永川区中医院 | A kind of pharmaceutical preparation and preparation method thereof for treating purulent sinusitis |
CN105311144A (en) * | 2015-11-28 | 2016-02-10 | 史克勇 | Compound preparation containing rhizoma cimicifugae |
CN106309974A (en) * | 2016-08-29 | 2017-01-11 | 杨程凯 | Traditional chinese medicine composition |
CN106727927A (en) * | 2016-12-12 | 2017-05-31 | 湖北中医药大学 | Rhinitis chronic chewing gum |
CN108186734A (en) * | 2018-03-13 | 2018-06-22 | 青岛大学附属医院 | A kind of rhinitis clinic externally applied drug and preparation method thereof |
CN111184770A (en) * | 2020-02-12 | 2020-05-22 | 常德集智生物科技有限公司 | Green rhinitis relieving lotion |
CN116983350A (en) * | 2023-09-19 | 2023-11-03 | 湖南中医药大学第一附属医院(中医临床研究所) | Traditional Chinese medicine composition for treating allergic rhinitis, preparation method and application |
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