CN1513489A - Enteroclysis liquid medicine for treating renal failure and its prepn. method - Google Patents

Enteroclysis liquid medicine for treating renal failure and its prepn. method Download PDF

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Publication number
CN1513489A
CN1513489A CNA031081568A CN03108156A CN1513489A CN 1513489 A CN1513489 A CN 1513489A CN A031081568 A CNA031081568 A CN A031081568A CN 03108156 A CN03108156 A CN 03108156A CN 1513489 A CN1513489 A CN 1513489A
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China
Prior art keywords
radix
renal failure
salviae miltiorrhizae
flos carthami
rhizoma rhei
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CN1232275C (en
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叶传蕙
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TIANYUAN PHARMACEUTICAL FACTORY HAINAN
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TIANYUAN PHARMACEUTICAL FACTORY HAINAN
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Abstract

A Chinese medicine in the form of enema liquid for treating acute or chronic renal failure is prepared from 4 Chinese-medicinal materials: rhubarb, red sage root, safflower and astragalus root 1.5:1:1:1.5 through decocting, filtering, sterilizing and concentrating.

Description

Renal failure health enema and preparation method thereof
Technical field the present invention relates to a kind of prescription that is mainly used in the acute and chronic renal failure Chinese medicine preparation renal failure health enema of treatment and preparation method thereof.
The background technology renal failure comprises acute renal failure (ARF) and chronic renal failure (CRF).Acute renal failure is because the various causes of disease cause the critical syndrome due to renal function (a few hours or a couple of days) carrying out property decline sharp in a short time, mainly shows as the retention of nitrogen matter product, water, electrolyte and acid base imbalance.Being found in a plurality of subjects such as inside and outside, woman, product, youngster, infection and wound, is one of modal severe crisis clinically, the mortality rate height, and prognosis is dangerous.Chronic renal failure, be because various chronic renal diseases develop into the serious syndrome due to late period, mainly show as water, electrolyte and acid base imbalance, azotemia and whole body multisystem are damaged, and have a strong impact on numerous patients' quality of life and life security.Modern medicine comprises conservative treatment and non-conservative treatment to the Therapeutic Method of acute and chronic renal failure.Conservative treatment is being that main drug treatment does not still have important breakthrough mainly based on the composite treatment at various complication preventions and treatment at nephridial tissue reparation and graft function.Non-conservative treatment comprises dialysis and renal transplantation, is bringing into play important effect aspect the treatment of handling critical complication of acute and chronic renal failure and patients with terminal, but still is having many weak links and blank spot.Still unresolved as the rejection of renal transplantation and kidney derived difficulty etc.And dialysis treatment only is an alternative medicine, soon should substitute kidney by dialysis from human body harmful and the noxious substance that urine excretes, and the function of kidney own fails to be restored owing to organic lesion.Because dialysis therapy technical operation complexity, complication is many, and patient's financial burden is big, only has about 20% so can accept the Patients with Chronic Renal Failure of dialysis treatment, and what can carry out kidney transplantation treatment is number still less (less than 1/100).As seen, the how acute or chronic renal failure of effectively preventing is still world today's medical circle a great problem anxious to be solved.
Summary of the invention the purpose of this invention is to provide a kind of prescription for the treatment of acute or chronic renal failure Chinese medicine preparation renal failure health enema that is mainly used in.
Another purpose of the present invention provides the preparation method of the acute or chronic renal failure Chinese medicine preparation renal failure health coloclysis intestinal juice of this treatment.
The object of the present invention is achieved like this: medicine of the present invention is to be made by the following weight ratio example: Radix Et Rhizoma Rhei, Radix Salviae Miltiorrhizae, Flos Carthami, the Radix Astragali are 1.5: 1: 1: 1.5,
Above-mentioned part by weight is made medicine production method of the present invention is:
Radix Et Rhizoma Rhei and Radix Salviae Miltiorrhizae, Flos Carthami and the Radix Astragali are dropped into respectively in the extraction pot, add water and respectively decoct 3 times, decocted 45 minutes at every turn, filter, merging filtrate is evaporation and concentration respectively, Radix Et Rhizoma Rhei, Radix Salviae Miltiorrhizae extract are concentrated into 1: 1.5 (ml: g); Flos Carthami, Radix Astragali extractive solution are concentrated into 1: 2.2, and (ml: g) concentration, Radix Et Rhizoma Rhei, Radix Salviae Miltiorrhizae concentrated solution add ethanol makes the alcohol amount of containing 70%, transfers pH8 with caustic lye of soda; Flos Carthami, Radix Astragali concentrated solution add ethanol to be made and contains alcohol amount 70% (uncomfortable pH); Stir evenly respectively, airtight leaving standstill, wait to be sunken to tank bottoms after, draw above-mentioned clear liquid filtering, above-mentioned two filtrates are merged, reclaim ethanol, add water and dilute in right amount, filter to there not being the alcohol flavor, (the ml: g), add ethanol again and make the alcohol amount of containing 80%, stir evenly airtight leaving standstill that is concentrated into 1: 5, filtering is reclaimed ethanol to not having the alcohol flavor, thin up to 1: 5 (ml: g), filter, adjust pH is 5~7, add tween 80, mixing, packing, sterilization, packing, promptly.
Beneficial effect of the present invention is: this medicine is the pure Chinese medicinal preparation of treatment renal failure, its prescription and production method thereof are simple, main by the general action after absorbing, renal blood flow increasing, improve renal microcirculation, alleviate the renal tubular necrosis degree, promote epithelial Regeneration and Repair such as downright bad renal tubules.
The invention will be further described below in conjunction with embodiment for the specific embodiment: according to component ratio take by weighing Radix Et Rhizoma Rhei 1500g, Radix Salviae Miltiorrhizae 1000g, Flos Carthami 1000g, Radix Astragali 1500g amount to 5000g, drop into Radix Et Rhizoma Rhei and Radix Salviae Miltiorrhizae, Flos Carthami and the Radix Astragali in the extraction pot respectively, adding water respectively decocts 3 times, the each decoction 45 minutes, filter, merging filtrate is evaporation and concentration respectively, Radix Et Rhizoma Rhei, Radix Salviae Miltiorrhizae extract are concentrated into 1: 1.5 (ml: g); Flos Carthami, Radix Astragali extractive solution are concentrated into 1: 2.2, and (ml: g) concentration, Radix Et Rhizoma Rhei, Radix Salviae Miltiorrhizae concentrated solution add ethanol makes the alcohol amount of containing 70%, transfers pH8 with caustic lye of soda; Flos Carthami, Radix Astragali concentrated solution add ethanol to be made and contains alcohol amount 70% (uncomfortable pH).Stir evenly respectively, airtight leaving standstill, wait to be sunken to tank bottoms after, draw the supernatant filtering.Above-mentioned two filtrates are merged, reclaim ethanol to there not being the alcohol flavor.Add water and dilute in right amount, filter, (the ml: g), add ethanol again and make and contain alcohol amount 80%, stir evenly airtight leaving standstill that is concentrated into 1: 5, filtering is reclaimed ethanol to not having the alcohol flavor, thin up to 1: 5 (ml: g), filter, transfer pH (5~7) value, add tween 80, mixing, packing, sterilization, packing, promptly.

Claims (3)

1, a kind of prescription of renal failure health enema is characterized in that: the prescription of renal failure health enema is made up of Chinese herb rhubarb, Radix Salviae Miltiorrhizae, Flos Carthami, the Radix Astragali.
2, the prescription of renal failure health enema according to claim 1 is characterized in that: the part by weight of each composition is that Radix Et Rhizoma Rhei, Radix Salviae Miltiorrhizae, Flos Carthami, the Radix Astragali are 1.5: 1: 1: 1.5.
3, a kind of preparation method that is used for above-mentioned renal failure health enema is characterized by:
(a) taking by weighing Radix Et Rhizoma Rhei, Radix Salviae Miltiorrhizae, Flos Carthami, the Radix Astragali by the weight ratio requirement of each composition is 1.5: 1: 1: after 1.5, drop into Radix Et Rhizoma Rhei and Radix Salviae Miltiorrhizae, Flos Carthami and the Radix Astragali in the extraction pot respectively, adding water respectively decocts 3 times, the each decoction 45 minutes, filter, merging filtrate is evaporation and concentration respectively, Radix Et Rhizoma Rhei, Radix Salviae Miltiorrhizae extract are concentrated into 1: 1.5 (ml: g); Flos Carthami, Radix Astragali extractive solution are concentrated into 1: 2.2 (ml: g) concentration;
(b) Radix Et Rhizoma Rhei, Radix Salviae Miltiorrhizae concentrated solution add ethanol and make the alcohol amount of containing 70%, transfer pH8 with caustic lye of soda; Flos Carthami, Radix Astragali concentrated solution add ethanol to be made and contains alcohol amount 70% (uncomfortable pH); Stir evenly respectively, airtight leaving standstill, wait to be sunken to tank bottoms after, draw the supernatant filtering;
(c) above-mentioned two filtrates are merged, reclaim ethanol to there not being the alcohol flavor; Add water and dilute in right amount, filter, be concentrated into 1: 5 (m1: g), add ethanol again and make and contain alcohol amount 80%, stir evenly, airtight leaving standstill, filtering is reclaimed ethanol to not having the alcohol flavor, thin up to 1: 5 (ml: g), filter, adjust pH (5~7), add tween 80, mixing;
(d) packing, sterilization, packing gets product after the assay was approved.
CN 03108156 2003-03-23 2003-03-23 Enteroclysis liquid medicine for treating renal failure and its prepn. method Expired - Lifetime CN1232275C (en)

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CN 03108156 CN1232275C (en) 2003-03-23 2003-03-23 Enteroclysis liquid medicine for treating renal failure and its prepn. method

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Application Number Priority Date Filing Date Title
CN 03108156 CN1232275C (en) 2003-03-23 2003-03-23 Enteroclysis liquid medicine for treating renal failure and its prepn. method

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CN1232275C CN1232275C (en) 2005-12-21

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102475764A (en) * 2010-11-30 2012-05-30 西安世纪盛康药业有限公司 Preparation method of Shenkang injection
CN102475757A (en) * 2010-11-30 2012-05-30 西安世纪盛康药业有限公司 Kidney-strengthening externally applied compound preparation for treating chronic renal failure and preparation method of compound preparation
CN102475756A (en) * 2010-11-30 2012-05-30 西安世纪盛康药业有限公司 Shenkang injection compound preparation for treating chronic renal failure and preparation method of Shenkang injection compound preparation
CN104983987A (en) * 2015-08-17 2015-10-21 黎颖 Traditional Chinese medicine colon dialyzate treating chronic renal failure

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102475764A (en) * 2010-11-30 2012-05-30 西安世纪盛康药业有限公司 Preparation method of Shenkang injection
CN102475757A (en) * 2010-11-30 2012-05-30 西安世纪盛康药业有限公司 Kidney-strengthening externally applied compound preparation for treating chronic renal failure and preparation method of compound preparation
CN102475756A (en) * 2010-11-30 2012-05-30 西安世纪盛康药业有限公司 Shenkang injection compound preparation for treating chronic renal failure and preparation method of Shenkang injection compound preparation
CN102475757B (en) * 2010-11-30 2013-10-16 西安世纪盛康药业有限公司 Kidney-strengthening externally applied compound preparation for treating chronic renal failure and preparation method of compound preparation
CN102475756B (en) * 2010-11-30 2014-03-19 西安世纪盛康药业有限公司 Shenkang injection compound preparation for treating chronic renal failure and preparation method of Shenkang injection compound preparation
CN104983987A (en) * 2015-08-17 2015-10-21 黎颖 Traditional Chinese medicine colon dialyzate treating chronic renal failure
CN104983987B (en) * 2015-08-17 2020-10-16 黎颖 Traditional Chinese medicine colon dialysis liquid for treating chronic renal failure

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