CN104524342A - Traditional Chinese medicine preparation for lowering high blood pressure, high blood sugar, high cholesterol, high uric acid and maintaining vigor and preparation method of plaster of traditional Chinese medicine preparation - Google Patents
Traditional Chinese medicine preparation for lowering high blood pressure, high blood sugar, high cholesterol, high uric acid and maintaining vigor and preparation method of plaster of traditional Chinese medicine preparation Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
- A61K36/424—Gynostemma
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/68—Plantaginaceae (Plantain Family)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/90—Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
The invention discloses a traditional Chinese medicine preparation for lowering high blood pressure, high blood sugar, high cholesterol, high uric acid and maintaining vigor. The traditional Chinese medicine preparation is prepared from the following traditional Chinese medicines: semen coicis, semen cassia, lotus leaf, plantain herb, gynostemma pentaphyllum, puerarin, rhizoma atractylodis macrocephalae, corn stigma, smilax glabra, chrysanthemum morifolium ramat and American ginseng. The preparation method of the traditional Chinese medicine preparation for lowering high blood pressure, high blood sugar, high cholesterol, high uric acid and maintaining vigor comprises the following steps: 1 adding water and decocting the traditional Chinese medicines twice, respectively filtering detection which is decocted twice, and merging and concentrating filtrate; and 2 adding xylitol to the concentrated liquid, and mixing into a hanging flag shape, namely the product of the traditional Chinese medicine preparation for lowering high blood pressure, high blood sugar, high cholesterol, high uric acid and maintaining vigor. According to the traditional Chinese medicine preparation for lowering high blood pressure, high blood sugar, high cholesterol, high uric acid and maintaining vigor, disclosed by the invention, the semen coicis has the efficacies of tonifying the spleen, excreting dampness, removing numbness, and relieving diarrhea; the semen cassia has the efficacies of clearing the liver, improving vision, and loosening the bowels to relieve constipation, so as to achieve the effects of lowering uric acid, high blood sugar, high cholesterol and high blood pressure. According to the preparation method of the traditional Chinese medicine preparation for lowering high blood pressure, high blood sugar, high cholesterol, high uric acid and maintaining vigor, disclosed by the invention, the effective components of the medicine can be effectively extracted by decoction twice, and the prepared plaster is convenient to use.
Description
Technical field
The present invention relates to the preparation method of a kind of Chinese medicine preparation and unguentum thereof, particularly relate to a kind of four and fall the preparation method of protecting first Chinese medicine preparation and unguentum thereof.
Background technology
Along with the improvement of living condition and the change of dietary structure, hypertension, hyperglycemia, hyperlipidemia, hyperuricemia have become frequently-occurring disease, the commonly encountered diseases of common people, and in ascendant trend year by year, have become the pertinacious disease of social recognition, often do not healed all the life.The hypertensive incidence rate of Patients with Hyperuricemia is 57.97%, and the incidence rate of hyperglycemia is that 15.94% , Xie hyperuricemia all exists dependency with incidence rate that is fat, hyperlipidemia.Therefore hyperuricemia, hypertension, hyperglycemia and hyperlipidemia be called " four high ".How relevant its cause of disease, pathogenesis be, intricate, pays close attention to and research more, there is no effective Therapeutic Method at present though medical circles have.Doctor trained in Western medicine is treated usually respectively to four height, and patient usually needs to take medicine all the life, and is chemicals, and the object for the treatment of suppresses or maintain the state of an illness for master, and its side effect is usually bound to arouse fear.
Summary of the invention
Treating the not good defect of osteoporotic curative effect of medication to overcome in prior art, providing a kind of four to fall the preparation method of protecting first Chinese medicine preparation and unguentum thereof.
The present invention is realized by following proposal:
A kind of four fall the first Chinese medicine preparation of guarantor, and comprise monarch drug, ministerial drug and adjuvant drug, in mass parts, described monarch drug comprises Semen Coicis 10-30 part, Semen Cassiae 15-30 part;
Described ministerial drug comprises Folium Nelumbinis 10-30 part, Herba Plantaginis 10-30 part, Herb Gynostemmae Pentaphylli 15-30 part, Radix Puerariae 15-30 part, Rhizoma Atractylodis Macrocephalae 10-15 part;
Described adjuvant drug comprises Rhizoma Smilacis Glabrae 15-30 part, Stigma Maydis 15-30 part, Flos Chrysanthemi 15-30 part, Radix Panacis Quinquefolii 10-15 part.
Described monarch drug comprises Semen Coicis 15 parts, Semen Cassiae 20 parts;
Described ministerial drug comprises 10 parts, Folium Nelumbinis, Herba Plantaginis 15 parts, Herb Gynostemmae Pentaphylli 20 parts, Radix Puerariae 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts;
Described adjuvant drug comprises Rhizoma Smilacis Glabrae 20 parts, Stigma Maydis 20 parts, Flos Chrysanthemi 15 parts, Radix Panacis Quinquefolii 10 parts.
In mass parts, this Chinese medicine preparation also comprises xylitol 30-100 part.
This Chinese medicine preparation is granule, aqueous solvent, capsule or unguentum.
Four fall a preparation method of protecting first unguentum, comprise the following steps:
The first step, by Semen Coicis, Semen Cassiae, Folium Nelumbinis, Herba Plantaginis, Herb Gynostemmae Pentaphylli, Radix Puerariae, the Rhizoma Atractylodis Macrocephalae, Stigma Maydis, Rhizoma Smilacis Glabrae, Flos Chrysanthemi, Radix Panacis Quinquefolii ladies and gentlemen decocting for Chinese herbal medicine, filtering decocting the decocting liquid obtained, filtrate being concentrated into the concentrated solution that density is 1.1-1.3 g/mL;
Second step, adds a small amount of xylitol in concentrated solution, is adjusted to and hangs flag shape, be four and fall the finished product protecting first unguentum.
In a first step, described ladies and gentlemen's Chinese medicine decocts with water through twice, and the first time of twice decoction decocts as 100-110 minute, and second time decocts as 60-90 minute, merges and be concentrated into the concentrated solution that density is 1.1g/mL after twice decoction after filtrate being filtered respectively.
In mass parts, the consumption of described ladies and gentlemen's Chinese medicine is as follows: Semen Coicis 10-30 part, Semen Cassiae 15-30 part, Folium Nelumbinis 10-30 part, Herba Plantaginis 10-30 part, Herb Gynostemmae Pentaphylli 15-30 part, Radix Puerariae 15-30 part, Rhizoma Atractylodis Macrocephalae 10-15 part, Rhizoma Smilacis Glabrae 15-30 part, Stigma Maydis 15-30 part, Flos Chrysanthemi 15-30 part, Radix Panacis Quinquefolii 10-15 part.
In mass parts, the consumption of described xylitol is 30-100 part.
Beneficial effect of the present invention is:
1. of the present invention a kind of four fall and protect that first Chinese medicine preparation adopts Semen Coicis, Semen Cassiae is monarch drug, Semen Coicis has spleen invigorating eliminating dampness by diuresis, effect of eliminating impediment antidiarrheal, Semen Cassiae can liver heat removing and eyesight improving, loosening bowel to relieve constipation, again with Folium Nelumbinis, Herba Plantaginis etc. for ministerial drug, clearing away summer-heat, sending up the lucid YANG, invigorating spleen to remove dampness, thus reach uric acid resisting, blood sugar lowering, blood fat reducing and hypotensive activity;
2. of the present invention a kind of four fall protect first unguentum preparation method by twice decoction, effectively can extract the effective ingredient of medicine, the unguentum made is easy to use.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described:
Embodiment 1
A kind of four fall the first Chinese medicine preparation of guarantor, and comprise monarch drug, ministerial drug and adjuvant drug, in mass parts, described monarch drug comprises Semen Coicis 10 parts, Semen Cassiae 15 parts;
Described ministerial drug comprises 30 parts, Folium Nelumbinis, Herba Plantaginis 30 parts, Herb Gynostemmae Pentaphylli 30 parts, Radix Puerariae 30 parts, the Rhizoma Atractylodis Macrocephalae 15 parts;
Described adjuvant drug comprises Rhizoma Smilacis Glabrae 15 parts, Stigma Maydis 15 parts, Flos Chrysanthemi 15 parts, Radix Panacis Quinquefolii 10 parts.
It is granule, aqueous solvent, capsule or unguentum.
Four fall a preparation method of protecting first unguentum, comprise the following steps:
The first step, Semen Coicis, Semen Cassiae, Folium Nelumbinis, Herba Plantaginis, Herb Gynostemmae Pentaphylli, Radix Puerariae, the Rhizoma Atractylodis Macrocephalae, Stigma Maydis, Rhizoma Smilacis Glabrae, Flos Chrysanthemi, Radix Panacis Quinquefolii ladies and gentlemen Chinese medicine are decocted with water twice, the decocting liquid that twice decoction obtains is filtered respectively, filtrate is merged and is concentrated into the concentrated solution that density is 1.2g/mL; Wherein, it is 105 minutes that the first time of twice decoction decocts, and it is 75 minutes that second time decocts;
Second step, adds xylitol 70 parts in concentrated solution, is adjusted to and hangs flag shape, be four and fall the finished product protecting first unguentum.
The present invention adds the xylitol not having and increase blood glucose effect, improves the present invention four and falls the first Chinese medicine preparation of guarantor to the suitability of diabetes patient.
Embodiment 2
A kind of four fall the first Chinese medicine preparation of guarantor, and comprise monarch drug, ministerial drug and adjuvant drug, in mass parts, described monarch drug comprises Semen Coicis 30 parts, Semen Cassiae 30 parts;
Described ministerial drug comprises 10 parts, Folium Nelumbinis, Herba Plantaginis 10 parts, Herb Gynostemmae Pentaphylli 15 parts, Radix Puerariae 15 parts, the Rhizoma Atractylodis Macrocephalae 10 parts;
Described adjuvant drug comprises Rhizoma Smilacis Glabrae 30 parts, Stigma Maydis 30 parts, Flos Chrysanthemi 30 parts, Radix Panacis Quinquefolii 15 parts.
It is granule, aqueous solvent, capsule or unguentum.
Four fall a preparation method of protecting first unguentum, comprise the following steps:
The first step, Semen Coicis, Semen Cassiae, Folium Nelumbinis, Herba Plantaginis, Herb Gynostemmae Pentaphylli, Radix Puerariae, the Rhizoma Atractylodis Macrocephalae, Stigma Maydis, Rhizoma Smilacis Glabrae, Flos Chrysanthemi, Radix Panacis Quinquefolii ladies and gentlemen Chinese medicine are decocted with water twice, the decocting liquid that twice decoction obtains is filtered respectively, filtrate is merged and is concentrated into the concentrated solution that density is 1.1g/mL; Wherein, it is 110 minutes that the first time of twice decoction decocts, and it is 90 minutes that second time decocts;
Second step, adds xylitol 100 parts in concentrated solution, is adjusted to and hangs flag shape, be four and fall the finished product protecting first unguentum.
Embodiment 3
A kind of four fall the first Chinese medicine preparation of guarantor, and comprise monarch drug, ministerial drug and adjuvant drug, in mass parts, described monarch drug comprises Semen Coicis 20 parts, Semen Cassiae 22 parts;
Described ministerial drug comprises 20 parts, Folium Nelumbinis, Herba Plantaginis 20 parts, Herb Gynostemmae Pentaphylli 22 parts, Radix Puerariae 22 parts, the Rhizoma Atractylodis Macrocephalae 13 parts;
Described adjuvant drug comprises Rhizoma Smilacis Glabrae 23 parts, Stigma Maydis 21 parts, Flos Chrysanthemi 24 parts, Radix Panacis Quinquefolii 12 parts.
It is granule, aqueous solvent, capsule or unguentum.
Four fall a preparation method of protecting first unguentum, comprise the following steps:
The first step, take Semen Coicis, Semen Cassiae, Folium Nelumbinis, Herba Plantaginis, Herb Gynostemmae Pentaphylli, Radix Puerariae, the Rhizoma Atractylodis Macrocephalae, Stigma Maydis, Rhizoma Smilacis Glabrae, Flos Chrysanthemi, Radix Panacis Quinquefolii ladies and gentlemen Chinese medicine according to the above ratio, then twice is decocted with water, the decocting liquid that twice decoction obtains is filtered respectively, filtrate is merged and is concentrated into the concentrated solution that density is 1.3g/mL; Wherein, it is 100 minutes that the first time of twice decoction decocts, and it is 70 minutes that second time decocts;
Second step, adds xylitol 30 parts in concentrated solution, is adjusted to and hangs flag shape, be four and fall the finished product protecting first unguentum.
One, in the present invention, the function of each component and function cure mainly;
The traditional Chinese medical science thinks hyperuricemia, hypertension, hyperglycemia and hyperlipidemia usually because of insufficiency of the spleen water retention, and the turbid poison of phlegm-damp is stagnated caused by body."Nei Jing" has cloud: " all damp-edema are full, all belong to spleen ".The spleen has the function to transport and transform nutrients, the precise and tiny and main the lucid yang sending up of clothization; Stomach receiving food and drink, digesting food and main the turbid descending.Spleen rises and is then good for, stomach fall then and, taste are the foundation of acquired constitution, the strong fortune of taste then defeated cloth essence of water and grain and moisten foster internal organs.Have eating and drinking without temperance again as ferritic is insufficiency of the spleen, easily cause dysfunction of spleen and stomach, ascending the clear and descending the turbid is smooth, and the water transporting that wets is obstructed, damp is detained in body, multiple abscess extremities joint dysfunction of the spleen in transportation, and turbid pathogen internal memory, accumulates in phlegm-damp, " General Treatise on the Cause and Symptoms of Diseases " has " weakness of the spleen and stomach, can not gram to disappear water slurry, therefore have phlegm retention also ".Jing-Yue Complete Works cloud: " excessive phlegm of madam, all makes so by middle void, and fruit makes spleen stomach strengthening be good for; as young and vigorous person flows, then water paddy is with food with change, all becomes QI and blood; here get Liu and be expectorant, precisely because can not change to the greatest extent, ten stay one or two; then one or two is expectorant; ten stay three or four, then three or four is expectorant, even stay its seven or eight; then but disappear vim and vigour day, and sputum day is many ".Research also confirms that the rising of serum cholesterol, triglyceride, metabolic arthritis, low density lipoprotein, LDL content is " expectorant is turbid " distinctive important biochemical indicator and material base.Certainly, surfeit delicious food, excessive tobacco and wine, motion are very less, excellent think of overstrain all can increase the weight of spleen and to suffer from a deficiency of the kidney damages, cause stopping in phlegm-damp and obesity, inside and outside conjunction because of, more easily cause a disease.
In the present invention, Semen Coicis returns spleen, stomach, lung three warp, cool in nature, and slightly sweet flavor, has spleen invigorating eliminating dampness by diuresis, effect of eliminating impediment antidiarrheal, heat clearing away toxin expelling, cures mainly diarrhea due to hypofunction of the spleen, the contracture of arthralgia chiefly caused by damp pathogen muscle arteries and veins; Semen Cassiae returns liver, kidney, large intestine three warp, can liver heat removing and eyesight improving, loosening bowel to relieve constipation, and curing mainly dizzy, the dryness of the intestine constipation of headache, is monarch drug.
Folium Nelumbinis GUIXIN, liver, spleen, gallbladder, lung meridian, clearing away summer-heat, sending up the lucid YANG, dizzy, the splenasthenic abdominal distention for the treatment of headache; Herba Plantaginis returns liver, kidney, urinary bladder channel, clearing away heat and promoting diuresis, removing heat from blood, removing toxic substances, treatment accumulation of heat in the urinary bladder; Dysuria, liver-heat conjunctival congestion; Laryngopharynx swelling and pain; Herb Gynostemmae Pentaphylli returns spleen, lung meridian, invigorating the spleen and benefiting QI, preventing phlegm from forming and stopping coughing, heat-clearing and toxic substances removing, insufficiency of the spleen, turbid phlegm obstructing in the lung, heat toxin syndrome; Radix Puerariae returns spleen, stomach warp, promoting the production of body fluid to quench thirst, and calentura excessive thirst, interior-heat are quenched one's thirst, insufficiency of the spleen chronic diarrhea; The Rhizoma Atractylodis Macrocephalae returns spleen, stomach warp, air making-up and spleen enlivening, dampness diuretic, anorexia and loose stool, distension and fullness in the abdomen, edema, dysuria, deficiency of the spleen causing weakness of QI.
Stigma Maydis returns bladder, liver, gallbladder meridian, inducing diuresis to remove edema, dampness removing jaundice eliminating, edema, dysuria, jaundice; Rhizoma Smilacis Glabrae returns liver, stomach warp, removing toxic substances dehumidifying, easing joint movement, and Flos Chrysanthemi returns lung, Liver Channel, disperse wind heat, liver heat removing and eyesight improving, suppressing liver-YANG, heat-clearing and toxic substances removing, excessive rising of liver-YANG, have a headache dizzy, Radix Panacis Quinquefolii GUIXIN, lung, stomach warp, boosting qi and nourishing yin, relieve inflammation or internal heat and promote the production of body fluid, treatment impairment of both QI and YIN tired tired thirsty.
Share can blood sugar lowering for all medicines above, and uric acid resisting, blood pressure lowering, blood fat reducing, reaches the effect that unit protected by controlling nocturnal emission with astringent drugs.
Of the present invention a kind of four fall protect first Chinese medicine preparation can for granule, aqueous solvent, capsule or unguentum, in following clinical curative effect analysis, clinical case four fall that to protect first unguentum be all of the present invention a kind of four fall the first Chinese medicine preparation of guarantor.
Two, clinical curative effect analysis
Four fall and protect first unguentum in Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine row clinical practice nearly 2 years, and I am institute's orthopedics department outpatient service and the routine patient of in-patient department 60, and biochemical analysis shows: blood glucose, blood fat, blood uric acid raise, and card belongs to: deficiency of spleen-YANG and kidneyYANG, fall the first unguentum of guarantor to taking four.
1, overall clinical curative effect
Total effective rate is 85.32%, and obvious effective rate is 8.13%, and overall clinical curative effect is obvious;
2, Syndrome in TCM marquis curative effect
Total effective rate is 94.2%, clinical recovery rate 17.3%, cure-remarkable-effectiveness rate 74.3%, and Syndrome in TCM marquis curative effect is obvious, and cure-remarkable-effectiveness rate is higher.
Three, clinical case
Model case 1
Patient Lee so-and-so, man, 58 years old, people from Jinxian County, Nanchang City, in November, 2013 suffered from gouty arthritis, and toes redness and swelling of joints burning pain, bends and stretches inconvenience, comes to go to a doctor.Repeatedly there is red and swollen heat pain for many years in main suit's biped toe, increase the weight of more than 1 year, walking disorder, have hypertension, diabetes and hyperlipidemia medical history, BP164/93mmHg, biochemical analysis shows: blood uric acid 531mmol/L, blood glucose 10.1mmol/L, fall the first unguentum 50g of guarantor to taking four, every day twice, after taking 1 week, biped toe red and swollen heat pain subtracts greatly, check blood uric acid 428mmol/L, blood glucose 7.4mmol/L, after now taking January again, pain is eliminated substantially, check blood uric acid, blood glucose are all normal, monitoring of blood pressure, all in normal range, 1 year so far, is followed up a case by regular visits to without recurrence.
Model case 2
Patient Chen, male, 68 years old, on December 21st, 2012, patient once had hyperuricemia, diabetes, hypertension history for many years, Long-term Oral blood sugar lowering, antihypertensive drug therapy, occur uncomfortable in chest in the recent period, deposit, fear of cold, breathe hard during cardiopalmus, cranial tinnitus, receive can, xerostomia is bitter, and two just adjust.Lower limb feel edema, light red tongue, during Sublingual, the stasis of blood is bent, thick and greasy fur, stringy pulse.BP:160/80mmHg, cardiac auscultation is without exception.Tcm diagnosis: cardiopalmus (flaccidity of the heart-yang, phlegm stagnation in collateral) dizzy Western medicine diagnose of quenching one's thirst: hypertension, coronary heart disease, diabetes, hyperuricemia, give four and fall the first unguentum 1 bag mouth clothes of guarantor, every day 1 dose, advise it to give doctor trained in Western medicine to take simultaneously, after March, blood pressure, blood glucose, blood fat and blood uric acid are all within normal range, and malaise symptoms disappears.
In clinical curative effect analysis and clinical case, used four fall and protect first unguentum, be prepare according to formula of Chinese materia medica preparation of the present invention and unguentum preparation method four fall and protect first unguentum finished product.
Although done comparatively detailed elaboration to technical scheme of the present invention and enumerated; be to be understood that; to those skilled in the art; amendment is made to above-described embodiment or adopts equivalent replacement scheme; this is apparent to those skilled in the art; these modifications or improvements without departing from theon the basis of the spirit of the present invention, all belong to the scope of protection of present invention.
Claims (8)
1. four fall the first Chinese medicine preparation of guarantor, and comprise monarch drug, ministerial drug and adjuvant drug, it is characterized in that: in mass parts, described monarch drug comprises Semen Coicis 10-30 part, Semen Cassiae 15-30 part;
Described ministerial drug comprises Folium Nelumbinis 10-30 part, Herba Plantaginis 10-30 part, Herb Gynostemmae Pentaphylli 15-30 part, Radix Puerariae 15-30 part, Rhizoma Atractylodis Macrocephalae 10-15 part;
Described adjuvant drug comprises Rhizoma Smilacis Glabrae 15-30 part, Stigma Maydis 15-30 part, Flos Chrysanthemi 15-30 part, Radix Panacis Quinquefolii 10-15 part.
2. according to claim 1 a kind of four fall the first Chinese medicine preparation of guarantor, it is characterized in that:
Described monarch drug comprises Semen Coicis 15 parts, Semen Cassiae 20 parts;
Described ministerial drug comprises 10 parts, Folium Nelumbinis, Herba Plantaginis 15 parts, Herb Gynostemmae Pentaphylli 20 parts, Radix Puerariae 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts;
Described adjuvant drug comprises Rhizoma Smilacis Glabrae 20 parts, Stigma Maydis 20 parts, Flos Chrysanthemi 15 parts, Radix Panacis Quinquefolii 10 parts.
3. according to claim 1 a kind of four fall the first Chinese medicine preparation of guarantor, and it is characterized in that: in mass parts, this Chinese medicine preparation also comprises xylitol 30-100 part.
4. the one four according to the arbitrary claim of claim 1-3 is fallen and is protected first Chinese medicine preparation, it is characterized in that: this Chinese medicine preparation is granule, aqueous solvent, capsule or unguentum.
5. four fall a preparation method of protecting first unguentum, it is characterized in that, comprise the following steps:
The first step, by Semen Coicis, Semen Cassiae, Folium Nelumbinis, Herba Plantaginis, Herb Gynostemmae Pentaphylli, Radix Puerariae, the Rhizoma Atractylodis Macrocephalae, Stigma Maydis, Rhizoma Smilacis Glabrae, Flos Chrysanthemi, Radix Panacis Quinquefolii ladies and gentlemen decocting for Chinese herbal medicine, filtering decocting the decocting liquid obtained, filtrate being concentrated into the concentrated solution that density is 1.1-1.3 g/mL;
Second step, adds a small amount of xylitol in concentrated solution, is adjusted to and hangs flag shape, be four and fall the finished product protecting first unguentum.
6. according to claim 5 a kind of four fall the preparation method of protecting first unguentum, it is characterized in that: in a first step, described ladies and gentlemen's Chinese medicine decocts with water through twice, the first time of twice decoction decocts as 100-110 minute, second time decocts as 60-90 minute, merges and be concentrated into the concentrated solution that density is 1.1g/mL after twice decoction after filtrate being filtered respectively.
7. according to claim 5 a kind of four fall the preparation method of protecting first unguentum, it is characterized in that: in mass parts, the consumption of described ladies and gentlemen's Chinese medicine is as follows: Semen Coicis 10-30 part, Semen Cassiae 15-30 part, Folium Nelumbinis 10-30 part, Herba Plantaginis 10-30 part, Herb Gynostemmae Pentaphylli 15-30 part, Radix Puerariae 15-30 part, Rhizoma Atractylodis Macrocephalae 10-15 part, Rhizoma Smilacis Glabrae 15-30 part, Stigma Maydis 15-30 part, Flos Chrysanthemi 15-30 part, Radix Panacis Quinquefolii 10-15 part.
8. according to claim 5 a kind of four fall the preparation method of protecting first unguentum, it is characterized in that: in mass parts, and the consumption of described xylitol is 30-100 part.
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