CN1232275C - Enteroclysis liquid medicine for treating renal failure and its prepn. method - Google Patents
Enteroclysis liquid medicine for treating renal failure and its prepn. method Download PDFInfo
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- CN1232275C CN1232275C CN 03108156 CN03108156A CN1232275C CN 1232275 C CN1232275 C CN 1232275C CN 03108156 CN03108156 CN 03108156 CN 03108156 A CN03108156 A CN 03108156A CN 1232275 C CN1232275 C CN 1232275C
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- radix
- salviae miltiorrhizae
- flos carthami
- rhizoma rhei
- renal failure
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Abstract
The present invention relates to a Chinese medicine preparation which is mainly used for treating acute renal failure and chronic renal failure, particularly to a formula of enema liquid for treating renal failure and a preparing method thereof. The medicine of the present invention is made of the ingredients of the following proportion by weight: 1.5 of rhubarb, 1 of red sage root, 1 of safflower and 1.5 of milkvetch root; the ingredients which are boiled with water are filtered, sterilized and concentrated. The medicine product is a pure Chinese medicine preparation for treating renal failure; the formula and the production method of the medicine product are simple; the medicine product increases the renal blood flow, improves the kidney microcirculation, mitigates the degree of renal tubular necrosis and promotes the regeneration and the rehabilitation of epithelial cells of necrotic renal tubules, etc. by the general action which is generated after the medicine product is absorbed.
Description
Technical field
The present invention relates to a kind of Chinese herbal medicine and preparation method thereof, particularly relate to a kind of enema for the treatment of renal failure and preparation method thereof.
Background technology
Renal failure comprises acute renal failure (ARF) and chronic renal failure (CRF).Acute renal failure is because the various causes of disease cause the critical syndrome due to renal function (a few hours or a couple of days) carrying out property decline sharp in a short time, mainly shows as the retention of nitrogen matter product, water, electrolyte and acid base imbalance.Being found in a plurality of subjects such as inside and outside, woman, product, youngster, infection and wound, is one of modal severe crisis clinically, the mortality rate height, and prognosis is dangerous.Chronic renal failure, be because various chronic renal diseases develop into the serious syndrome due to late period, mainly show as water, electrolyte and acid base imbalance, azotemia and whole body multisystem are damaged, and have a strong impact on numerous patients' quality of life and life security.Modern medicine comprises conservative treatment and non-conservative treatment to the Therapeutic Method of acute and chronic renal failure.Conservative treatment is being that main drug treatment does not still have important breakthrough mainly based on the composite treatment at various complication preventions and treatment at nephridial tissue reparation and graft function.Non-conservative treatment comprises dialysis and renal transplantation, is bringing into play important effect aspect the treatment of handling critical complication of acute and chronic renal failure and patients with terminal, but still is having many weak links and blank spot.Still unresolved as the rejection of renal transplantation and kidney derived difficulty etc.Dialysis treatment only is an alternative medicine, soon should excrete by hemodialysis from the harmful and noxious substance that urine excretes, but the function of kidney itself can not be restored owing to organic lesion.Because dialysis therapy technical operation complexity, complication is many, and patient's financial burden is big, only has about 20% so can accept the Patients with Chronic Renal Failure of dialysis treatment, and what can carry out kidney transplantation treatment is number still less (less than 1/100).As seen, the how acute and chronic renal failure of effectively preventing is still a great problem that world today's medical circle needs to be resolved hurrily.
Summary of the invention
The purpose of this invention is to provide a kind of enema that is used for the treatment of acute and chronic renal failure and preparation method thereof.
The enema of treatment renal failure provided by the present invention is by the feedstock production of following ratio of weight and number:
Radix Et Rhizoma Rhei 1.5
Radix Salviae Miltiorrhizae 1
Flos Carthami 1
The Radix Astragali 1.5.
The present invention treats the preparation method of renal failure enema, may further comprise the steps:
(a) Radix Et Rhizoma Rhei by ratio of weight and the number of copies: Radix Salviae Miltiorrhizae: Flos Carthami: the Radix Astragali=1.5: 1: 1: 1.5 take by weighing raw material; Drop into Radix Et Rhizoma Rhei and Radix Salviae Miltiorrhizae, Flos Carthami and the Radix Astragali in the extraction pot respectively, adding water respectively decocts 3 times, each 45 minutes, decoction liquor is filtered the back and is merged reconcentration, the decoction liquor of Radix Et Rhizoma Rhei and Radix Salviae Miltiorrhizae is concentrated into 1.5 gram dry/milliliter decoction liquor, get Radix Et Rhizoma Rhei and Radix Salviae Miltiorrhizae concentrated solution, the decoction liquor of the Flos Carthami and the Radix Astragali is concentrated into 2.2 gram dry/milliliter decoction liquor, gets Flos Carthami and Radix Astragali concentrated solution;
(b) add ethanol in Radix Et Rhizoma Rhei and the Radix Salviae Miltiorrhizae concentrated solution, making alcoholic acid final concentration is 70%, regulates pH to 8 with sodium hydroxide, staticly settles and gets supernatant, gets Radix Et Rhizoma Rhei and Radix Salviae Miltiorrhizae supernatant; Add ethanol in Flos Carthami and the Radix Astragali concentrated solution, making alcoholic acid final concentration is 70%, staticly settles and gets supernatant, gets Flos Carthami and Radix Astragali supernatant;
(c) Radix Et Rhizoma Rhei and Radix Salviae Miltiorrhizae, Flos Carthami and Radix Astragali supernatant are merged, remove ethanol to nothing alcohol flavor, the thin up after-filtration, filtrate is concentrated into 5 gram dry/milliliter filtrates; Add ethanol, making alcoholic acid final concentration is 80%, staticly settles, and crosses the leaching supernatant; Remove ethanol to not having the alcohol flavor, thin up to 5 gram dry/ml soln; Transfer pH to 5-7, add tween 80, mixing obtains product.
The described product that obtains also need pass through packing, sterilization, obtains finished product after check, the packing.
Beneficial effect of the present invention is: this medicine is the pure Chinese medicinal preparation of treatment renal failure, its prescription and production method thereof are simple, main by the general action after absorbing, renal blood flow increasing, improve renal microcirculation, alleviate the renal tubular necrosis degree, promote epithelial Regeneration and Repair such as downright bad renal tubules.
The specific embodiment
Take by weighing Radix Et Rhizoma Rhei 1500g, Radix Salviae Miltiorrhizae 1000g, Flos Carthami 000g, Radix Astragali 1500g amounts to 5000g, Radix Et Rhizoma Rhei and Radix Salviae Miltiorrhizae, Flos Carthami and the Radix Astragali are dropped into respectively in the extraction pot, add water and respectively decoct 3 times, decocted 45 minutes at every turn, filter, merging filtrate is evaporation and concentration respectively, and the decoction liquor of Radix Et Rhizoma Rhei and Radix Salviae Miltiorrhizae is concentrated into 1.5 gram dry/milliliter decoction liquor, gets Radix Et Rhizoma Rhei and Radix Salviae Miltiorrhizae concentrated solution, the decoction liquor of the Flos Carthami and the Radix Astragali is concentrated into 2.2 gram dry/milliliter decoction liquor, gets Flos Carthami and Radix Astragali concentrated solution; Add ethanol in Radix Et Rhizoma Rhei and the Radix Salviae Miltiorrhizae concentrated solution, making alcoholic acid final concentration is 70%, transfers pH to 8 with caustic lye of soda.Add ethanol in Flos Carthami and the Radix Astragali concentrated solution, making alcoholic acid final concentration is 70% (uncomfortable pH).Stir evenly respectively, airtight leaving standstill, wait to be sunken to tank bottoms after, draw the supernatant filtering.Above-mentioned two filtrates are merged, reclaim ethanol to there not being the alcohol flavor.Add water and dilute in right amount, filter, filtrate is concentrated into 5 gram dry/milliliter filtrates.Add ethanol again, making alcoholic acid final concentration is 80%, stirs evenly, and airtight leaving standstill crossed the leaching supernatant.Reclaim ethanol to there not being the alcohol flavor, thin up to 5 gram dry/ml soln filters, and transfers pH to 5-7, adds tween 80, mixing, and packing, sterilization obtain finished product after check, the packing.
Claims (3)
1, a kind of enema for the treatment of renal failure is by the feedstock production of following ratio of weight and number:
Radix Et Rhizoma Rhei 1.5
Radix Salviae Miltiorrhizae 1
Flos Carthami 1
The Radix Astragali 1.5.
2, a kind of method for preparing the enema for the treatment of renal failure may further comprise the steps:
(a) Radix Et Rhizoma Rhei by ratio of weight and the number of copies: Radix Salviae Miltiorrhizae: Flos Carthami: the Radix Astragali=1.5: 1: 1: 1.5 take by weighing raw material; Drop into Radix Et Rhizoma Rhei and Radix Salviae Miltiorrhizae, Flos Carthami and the Radix Astragali in the extraction pot respectively, adding water respectively decocts 3 times, each 45 minutes, decoction liquor is filtered the back and is merged reconcentration, the decoction liquor of Radix Et Rhizoma Rhei and Radix Salviae Miltiorrhizae is concentrated into 1.5 gram dry/milliliter decoction liquor, get Radix Et Rhizoma Rhei and Radix Salviae Miltiorrhizae concentrated solution, the decoction liquor of the Flos Carthami and the Radix Astragali is concentrated into 2.2 gram dry/milliliter decoction liquor, gets Flos Carthami and Radix Astragali concentrated solution;
(b) add ethanol in Radix Et Rhizoma Rhei and the Radix Salviae Miltiorrhizae concentrated solution, making alcoholic acid final concentration is 70%, regulates pH to 8 with sodium hydroxide, staticly settles and gets supernatant, gets Radix Et Rhizoma Rhei and Radix Salviae Miltiorrhizae supernatant; Add ethanol in Flos Carthami and the Radix Astragali concentrated solution, making alcoholic acid final concentration is 70%, staticly settles and gets supernatant, gets Flos Carthami and Radix Astragali supernatant;
(c) Radix Et Rhizoma Rhei and Radix Salviae Miltiorrhizae, Flos Carthami and Radix Astragali supernatant are merged, remove ethanol to nothing alcohol flavor, the thin up after-filtration, filtrate is concentrated into 5 gram dry/milliliter filtrates; Add ethanol, making alcoholic acid final concentration is 80%, staticly settles, and crosses the leaching supernatant; Remove ethanol to not having the alcohol flavor, thin up to 5 gram dry/ml soln; Transfer pH to 5-7, add tween 80, mixing obtains product.
3, method according to claim 2 is characterized in that: the described product that obtains also need pass through packing, sterilization, obtains finished product after check, the packing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03108156 CN1232275C (en) | 2003-03-23 | 2003-03-23 | Enteroclysis liquid medicine for treating renal failure and its prepn. method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03108156 CN1232275C (en) | 2003-03-23 | 2003-03-23 | Enteroclysis liquid medicine for treating renal failure and its prepn. method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1513489A CN1513489A (en) | 2004-07-21 |
| CN1232275C true CN1232275C (en) | 2005-12-21 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 03108156 Expired - Lifetime CN1232275C (en) | 2003-03-23 | 2003-03-23 | Enteroclysis liquid medicine for treating renal failure and its prepn. method |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102475756B (en) * | 2010-11-30 | 2014-03-19 | 西安世纪盛康药业有限公司 | Shenkang injection compound preparation for treating chronic renal failure and preparation method of Shenkang injection compound preparation |
| CN102475764A (en) * | 2010-11-30 | 2012-05-30 | 西安世纪盛康药业有限公司 | Preparation method of Shenkang injection |
| CN102475757B (en) * | 2010-11-30 | 2013-10-16 | 西安世纪盛康药业有限公司 | Kidney-strengthening externally applied compound preparation for treating chronic renal failure and preparation method of compound preparation |
| CN104983987B (en) * | 2015-08-17 | 2020-10-16 | 黎颖 | Traditional Chinese medicine colon dialysis liquid for treating chronic renal failure |
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2003
- 2003-03-23 CN CN 03108156 patent/CN1232275C/en not_active Expired - Lifetime
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| Publication number | Publication date |
|---|---|
| CN1513489A (en) | 2004-07-21 |
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