CN104983987A - Traditional Chinese medicine colon dialyzate treating chronic renal failure - Google Patents

Traditional Chinese medicine colon dialyzate treating chronic renal failure Download PDF

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CN104983987A
CN104983987A CN201510501574.1A CN201510501574A CN104983987A CN 104983987 A CN104983987 A CN 104983987A CN 201510501574 A CN201510501574 A CN 201510501574A CN 104983987 A CN104983987 A CN 104983987A
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chinese medicine
renal failure
dialyzate
traditional chinese
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CN104983987B (en
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黎颖
熊维建
钟锦
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Abstract

The invention provides traditional Chinese medicine colon dialyzate treating chronic renal failure. The traditional Chinese medicine colon dialyzate comprises, by weight, 10-30 parts of astragalus membranaceus, 15-45 parts of angelica sinensis, 10-30 parts of codonopsis pilosula, 5-15 parts of ligusticum wallichii, 12-30 parts of raw rhubarb, 12-30 parts of raw oyster shell, 15-30 parts of dandelion, 5-15 parts of ganoderma lucidum, 6-10 parts of herb of snow of june, 3-9 parts of resina draconis, 3-9 parts of ternate buttercup root and 3-6 parts of ambrette musk mallow. The clinic experiment proves that the traditional Chinese medicine colon dialyzate has an obvious curative effect on treating the chronic renal failure. The traditional Chinese medicine colon dialyzate has a small number of adverse reactions, has the advantages of being high in safety, low in cost, convenient to operate and the like and is a safe and effective new method for treating the chronic renal failure.

Description

A kind of Chinese medicine colonic dialysis liquid for the treatment of chronic renal failure
Technical field
The present invention relates to the field of Chinese medicines, be a kind ofly mainly used in treating chronic kidney and decline the formula of Chinese medicine colonic dialysis liquid.
Background technology
Chronic renal failure (CRF) is by various primary renal disease or is secondary to kidney Progressive symmetric erythrokeratodermia that Other diseases causes and damages and the running down of renal function.When kidney damage develops into the homeostasis that can not maintain body, then cause the savings of the endotoxic metabolite of health, water and electrolyte and acid base imbalance, the Comprehensive Clinical symptom of the main manifestations of each system involvement of whole body.If effectively do not treated, by the physiological function of infringement organs, multisystem, the physical and mental health of grievous injury patient and quality of life.Current CRF sickness rate is in rising trend, and uremia has been Inpatients main causes of death.Up to now, both at home and abroad still mainly take to suit the medicine to the illness to the Therapeutic Method of chronic renal failure and the Comprehensive Treatment such as blood purification, particularly for chronic kidney disease 1-4 phase patient, still mainly taking symptomatic treatment to delay progression of disease, is being that main drug treatment there is no important breakthrough for nephridial tissue reparation and graft function.And enter the whole late stage patients of maintenance dialysis, because financial burden is large, complication is many, therefore the CRF patient that can accept maintenance dialysis treatment only has about 20%.Therefore, how effectively to prevent and treat chronic renal failure, one of study hotspot being still this professional field.
Previously the report of herbal drug enema in treatment renal failure is many, but traditional coloclysis to there is medicament mucosa permeability poor, be difficult to various toxin in adsorbate, and damage the problems such as intestinal mucosa.Recently for the deficiency of herbal enema, a kind of curative effect is provided certainly and the little colonic dialysis treatment of side effect.
Summary of the invention
The present invention relates to and a kind of Chinese medicine colonic dialysis liquid being used for the treatment of chronic renal failure is provided.Chinese medicine colonic dialysis liquid of the present invention is be prepared from by the raw material of following ratio of weight and number: the Radix Astragali: Radix Angelicae Sinensis: Radix Codonopsis: Rhizoma Chuanxiong: Radix Et Rhizoma Rhei: Concha Ostreae: Herba Taraxaci: Ganoderma: Serissa foetida: Sanguis Draxonis: Radix Ranunculi Ternati: Flos abelmoschi manihot: Serissa foetida is 10-30:15-45:10-30:5-15:12-30:12-30:15-30:5-15:5-10:3-9:3-9:3-6.
The preparation method of Chinese medicine colonic dialysis liquid of the present invention, comprise the following steps: after taking the Radix Astragali, Radix Angelicae Sinensis, Radix Codonopsis, Rhizoma Chuanxiong, Radix Et Rhizoma Rhei, Concha Ostreae, Herba Taraxaci, Ganoderma, Serissa foetida, Sanguis Draxonis, ram's horn, Flos abelmoschi manihot by the weight ratio requirement of each composition, dropped in extraction pot, decoct with water 3 times, each decoction 45 minutes, filters, after merging filtrate difference evaporation and concentration, add ethanol and make alcohol content 80%, stir evenly, airtight standing, filtering, reclaim ethanol extremely without alcohol taste, thin up, filters, adjusts pH value (5-7), subpackage, sterilizing, obtains finished product.The invention has the advantages that: 1. the present invention is a kind of pure Chinese medicinal preparation, preparation method is simple, mainly through the general action after colonic absorption, improves Renal microcirculation, alleviates renal fibrosis, thus improve renal function, alleviates Pathological damage.
Detailed description of the invention
embodiment 1,crude drug weight proportion: the Radix Astragali: Radix Angelicae Sinensis: Radix Codonopsis: Rhizoma Chuanxiong: Radix Et Rhizoma Rhei: Concha Ostreae: Herba Taraxaci: Ganoderma: Serissa foetida: Sanguis Draxonis: Radix Ranunculi Ternati: Flos abelmoschi manihot is 30:45:30:15:30:30:30:15:10:9:9:6, each taste medicine is by above-mentioned preparation method preparation, coloclysis use, one week 4 times.
embodiment 2,crude drug weight proportion: the Radix Astragali: Radix Angelicae Sinensis: Radix Codonopsis: Rhizoma Chuanxiong: Radix Et Rhizoma Rhei: Concha Ostreae: Herba Taraxaci: Ganoderma: Serissa foetida: Sanguis Draxonis: Radix Ranunculi Ternati: Flos abelmoschi manihot is 20:30:15:10:25:20:20:10:7:6:6:3, prepare by above-mentioned preparation method, adopt the lavation of colon dialysis machine total colectomy, one week 3 times.
The efficient combination of said medicine, coordinates mutually, and treatment chronic renal failure Be very effective, side effect is less.
The above results clinical data is as follows:.
1. clinical data:.
1.1 physical data: select to be diagnosed as a year May in August, 2013 to 2014 chronic kidney disease 2-4 phase patient 90 example, age 17-65 year, protopathy comprises chronic glomerulonephritis 46 example, hypertensive nephropathy 29 example, diabetic nephropathy 21 example, lupus nephritis 2 example, chronic pyelonephritis 1 example, polycystic kidney 1 example.Diagnostic criteria, with reference to " internal medicine " (the 5th edition), chronic renal failure diagnostic criteria.Patient is divided at random matched group, clyster group and colonic dialysis group, often organizes 30 examples.
1.2 methods: all cases give high-quality low protein diet and general doctor trained in Western medicine and to suit the medicine to the illness Supporting Therapy.Clyster group, on treatment of control group basis, to give in the embodiment of the present invention 1 colonic dialysis liquid coloclysis one week 4 times.Colonic dialysis group, on treatment of control group basis, gives colonic dialysis liquid in the embodiment of the present invention 2, adopts the lavation of colon dialysis machine total colectomy, one week 3 times, 15 days courses for the treatment of.
1.3 observation index: measure before and after treatment and respectively organize blood urea nitrogen (BUN), serum creatinine (Crea), hemoglobin (Hb), endogenous creatinine clearance rate (Ccr).
1.4 statistical method: application SPSS17.0 software kit carries out statistical analysis, measurement data with represent, adopt X 2inspection and t inspection.
2. result:.
2.1 renal functioies obviously improve: after treatment, clyster group and colonic dialysis group renal function level comparatively matched group all have clear improvement, and wherein comparatively clyster group is remarkable for colonic dialysis group curative effect.Before and after treatment three groups of BUN, Crea, Ccr tri-groups of differences have statistical significance ( p<0.05).
2.2 anemia situations are obviously improved: compared with matched group, and clyster group and colonic dialysis group are after treatment, and hemoglobin level obviously raises, and it is obvious that colonic dialysis group hemoglobin level raises comparatively clyster group.
2.3 adverse reaction rates: three groups of patients all do not occur obvious adverse reaction.
3. conclusion: this research finds, clyster group of the present invention and colonic dialysis group have significant curative effect to treatment chronic renal failure, and total colectomy dialysis curative effect of the present invention is better than traditional enema treatment, has untoward reaction few, the advantages such as safety is high, and cost is lower, easy to operate.

Claims (2)

1. treat a formula for the Chinese medicine colonic dialysis liquid of renal failure, it is characterized in that: formula is made up of Chinese medicine astragalus 10-30 part, Radix Angelicae Sinensis 15-45 part, Radix Codonopsis 10-30 part, Rhizoma Chuanxiong 5-15 part, Radix Et Rhizoma Rhei 12-30 part, Concha Ostreae 12-30 part, Herba Taraxaci 15-30 part, Ganoderma 5-15 part, Serissa foetida 5-10 part, Sanguis Draxonis 3-9 part, Radix Ranunculi Ternati 3-9 part, Flos abelmoschi manihot 3-6 part.
2. the formula of Chinese medicine colonic dialysis liquid according to claim 1, its preparation method is characterized as:
After taking Chinese medicine by the weight ratio requirement of each composition, dropped in extraction pot, decocted with water 3 times, each decoction 45 minutes, filters, after merging filtrate difference evaporation and concentration, add ethanol and make alcohol content 80%, stir evenly, airtight standing, filtering, reclaims ethanol extremely without alcohol taste, thin up, filter, adjust pH value (5-7), subpackage, sterilizing, obtains finished product.
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107158226A (en) * 2017-07-07 2017-09-15 李建国 A kind of Chinese medicine colonic dialysis liquid for being used to treat chronic renal failure
CN107551192A (en) * 2017-09-20 2018-01-09 江苏省中医院 A kind of Traditional Chinese medicine compound composition with treatment CKD and preparation method and application
CN114224941A (en) * 2022-02-08 2022-03-25 上海市奉贤区中医医院 Traditional Chinese medicine composition for treating chronic renal failure and application thereof

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Publication number Priority date Publication date Assignee Title
CN1513489A (en) * 2003-03-23 2004-07-21 海南天元制药厂 Enteroclysis liquid medicine for treating renal failure and its prepn. method
CN101716252A (en) * 2010-01-06 2010-06-02 刘兆全 Kidney-strengthening pill
CN103301355A (en) * 2013-07-01 2013-09-18 郝伟英 Preparation method of chronic renal failure colon dialysate
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CN1513489A (en) * 2003-03-23 2004-07-21 海南天元制药厂 Enteroclysis liquid medicine for treating renal failure and its prepn. method
CN101716252A (en) * 2010-01-06 2010-06-02 刘兆全 Kidney-strengthening pill
CN103301355A (en) * 2013-07-01 2013-09-18 郝伟英 Preparation method of chronic renal failure colon dialysate
CN103330868A (en) * 2013-07-01 2013-10-02 郝伟英 Intestinal tract replenishing liquid for chronic renal failure

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107158226A (en) * 2017-07-07 2017-09-15 李建国 A kind of Chinese medicine colonic dialysis liquid for being used to treat chronic renal failure
CN107551192A (en) * 2017-09-20 2018-01-09 江苏省中医院 A kind of Traditional Chinese medicine compound composition with treatment CKD and preparation method and application
CN114224941A (en) * 2022-02-08 2022-03-25 上海市奉贤区中医医院 Traditional Chinese medicine composition for treating chronic renal failure and application thereof

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