CN1499967A - 用于治疗膀胱疾病的k-阿片受体激动剂 - Google Patents
用于治疗膀胱疾病的k-阿片受体激动剂 Download PDFInfo
- Publication number
- CN1499967A CN1499967A CNA028073983A CN02807398A CN1499967A CN 1499967 A CN1499967 A CN 1499967A CN A028073983 A CNA028073983 A CN A028073983A CN 02807398 A CN02807398 A CN 02807398A CN 1499967 A CN1499967 A CN 1499967A
- Authority
- CN
- China
- Prior art keywords
- treatment
- bladder
- acetamide
- phenyl
- ethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrrole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Description
Claims (4)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10116978.7 | 2001-04-05 | ||
DE10116978A DE10116978A1 (de) | 2001-04-05 | 2001-04-05 | Kappa-Opiatagonisten für die Behandlung von Erkrankungen der Blase |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1499967A true CN1499967A (zh) | 2004-05-26 |
CN1268332C CN1268332C (zh) | 2006-08-09 |
Family
ID=7680492
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB028073983A Expired - Fee Related CN1268332C (zh) | 2001-04-05 | 2002-03-13 | 用于治疗膀胱疾病的k-阿片受体激动剂 |
Country Status (24)
Country | Link |
---|---|
US (1) | US20040157913A1 (zh) |
EP (2) | EP1397128B1 (zh) |
JP (1) | JP2004525165A (zh) |
KR (1) | KR100851938B1 (zh) |
CN (1) | CN1268332C (zh) |
AT (1) | ATE366109T1 (zh) |
AU (1) | AU2002254947B2 (zh) |
BR (1) | BR0208488A (zh) |
CA (1) | CA2443019C (zh) |
CY (1) | CY1109001T1 (zh) |
CZ (1) | CZ20032899A3 (zh) |
DE (2) | DE10116978A1 (zh) |
DK (1) | DK1397128T3 (zh) |
ES (1) | ES2290286T3 (zh) |
HK (1) | HK1064036A1 (zh) |
HU (1) | HUP0303910A3 (zh) |
MX (1) | MXPA03009099A (zh) |
MY (1) | MY136683A (zh) |
PL (1) | PL363540A1 (zh) |
PT (1) | PT1397128E (zh) |
RU (1) | RU2307651C2 (zh) |
SK (1) | SK13272003A3 (zh) |
WO (1) | WO2002080905A1 (zh) |
ZA (1) | ZA200308600B (zh) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10259245A1 (de) * | 2002-12-17 | 2004-07-01 | Merck Patent Gmbh | Derivate des Asimadolins mit kovalent gebundenen Säuren |
US20080090859A1 (en) * | 2003-10-30 | 2008-04-17 | Tioga Pharmaceuticals, Inc. | Use of Selective Opiate Receptor Modulators In the Treatment Of Neuropathy |
PL2136801T3 (pl) | 2007-03-30 | 2013-01-31 | Tioga Pharmaceuticals Inc | Agoniści kappa-opioidów do leczenia zespołu jelita drażliwego w postaci zmiennej i z dominującą biegunką |
NZ630471A (en) * | 2012-03-19 | 2016-04-29 | Wellesley Pharmaceuticals Llc | Extended-release formulation for reducing the frequency of urination and method of use thereof |
US8637538B1 (en) | 2012-12-14 | 2014-01-28 | Trevi Therapeutics, Inc. | Methods for treatment of pruritis |
US8987289B2 (en) | 2012-12-14 | 2015-03-24 | Trevi Therapeutics, Inc. | Methods for treating pruritus |
US20140179727A1 (en) | 2012-12-14 | 2014-06-26 | Trevi Therapeutics, Inc. | Methods for treating pruritus |
KR20210035854A (ko) | 2018-07-23 | 2021-04-01 | 트레비 테라퓨틱스, 인코포레이티드 | 만성 기침, 무호흡증 및 호흡곤란의 치료 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4215213A1 (de) * | 1992-05-09 | 1993-11-11 | Merck Patent Gmbh | Arylacetamide |
DE19523502A1 (de) * | 1995-06-28 | 1997-01-02 | Merck Patent Gmbh | Kappa-Opiatagonisten für entzündliche Darmerkrankungen |
DE19531464A1 (de) * | 1995-08-26 | 1997-02-27 | Merck Patent Gmbh | N-Methyl-N-[(1S-)-1-phenyl-2-((3S)-3-hydroxypyrrolidin 1-yl-)-ethyl]-2,2-diphenyl-acetamid |
US5859043A (en) * | 1996-06-11 | 1999-01-12 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Method for maintaining kidney function during surgery or severe trauma under general anesthesia |
US6201022B1 (en) * | 1997-03-27 | 2001-03-13 | Myorx, Inc. | Methods for treating neurotransmitter-mediated pain syndromes by topically administering an omega fatty acid |
US5965701A (en) * | 1997-12-23 | 1999-10-12 | Ferring Bv | Kappa receptor opioid peptides |
-
2001
- 2001-04-05 DE DE10116978A patent/DE10116978A1/de not_active Withdrawn
-
2002
- 2002-03-13 JP JP2002578944A patent/JP2004525165A/ja active Pending
- 2002-03-13 PT PT02724228T patent/PT1397128E/pt unknown
- 2002-03-13 KR KR1020037012331A patent/KR100851938B1/ko not_active IP Right Cessation
- 2002-03-13 DK DK02724228T patent/DK1397128T3/da active
- 2002-03-13 AT AT02724228T patent/ATE366109T1/de active
- 2002-03-13 US US10/474,312 patent/US20040157913A1/en not_active Abandoned
- 2002-03-13 HU HU0303910A patent/HUP0303910A3/hu unknown
- 2002-03-13 EP EP02724228A patent/EP1397128B1/de not_active Expired - Lifetime
- 2002-03-13 PL PL02363540A patent/PL363540A1/xx unknown
- 2002-03-13 AU AU2002254947A patent/AU2002254947B2/en not_active Ceased
- 2002-03-13 WO PCT/EP2002/002756 patent/WO2002080905A1/de active IP Right Grant
- 2002-03-13 CA CA002443019A patent/CA2443019C/en not_active Expired - Fee Related
- 2002-03-13 EP EP07111669A patent/EP1834640A3/de not_active Withdrawn
- 2002-03-13 BR BR0208488-0A patent/BR0208488A/pt not_active IP Right Cessation
- 2002-03-13 CZ CZ20032899A patent/CZ20032899A3/cs unknown
- 2002-03-13 RU RU2003130641/14A patent/RU2307651C2/ru active
- 2002-03-13 MX MXPA03009099A patent/MXPA03009099A/es active IP Right Grant
- 2002-03-13 DE DE50210422T patent/DE50210422D1/de not_active Expired - Lifetime
- 2002-03-13 ES ES02724228T patent/ES2290286T3/es not_active Expired - Lifetime
- 2002-03-13 CN CNB028073983A patent/CN1268332C/zh not_active Expired - Fee Related
- 2002-03-13 SK SK1327-2003A patent/SK13272003A3/sk not_active Application Discontinuation
- 2002-04-02 MY MYPI20021192A patent/MY136683A/en unknown
-
2003
- 2003-11-04 ZA ZA200308600A patent/ZA200308600B/en unknown
-
2004
- 2004-09-07 HK HK04106732A patent/HK1064036A1/xx not_active IP Right Cessation
-
2007
- 2007-09-25 CY CY20071101231T patent/CY1109001T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
AU2002254947B2 (en) | 2007-06-07 |
MXPA03009099A (es) | 2004-02-12 |
CA2443019C (en) | 2009-12-29 |
ES2290286T3 (es) | 2008-02-16 |
DE10116978A1 (de) | 2002-10-10 |
EP1834640A2 (de) | 2007-09-19 |
CY1109001T1 (el) | 2014-07-02 |
EP1834640A3 (de) | 2009-12-23 |
CN1268332C (zh) | 2006-08-09 |
RU2003130641A (ru) | 2005-03-10 |
DE50210422D1 (de) | 2007-08-16 |
PL363540A1 (en) | 2004-11-29 |
US20040157913A1 (en) | 2004-08-12 |
WO2002080905A1 (de) | 2002-10-17 |
BR0208488A (pt) | 2004-03-02 |
KR100851938B1 (ko) | 2008-08-12 |
HUP0303910A3 (en) | 2005-04-28 |
EP1397128A1 (de) | 2004-03-17 |
ATE366109T1 (de) | 2007-07-15 |
KR20040025909A (ko) | 2004-03-26 |
SK13272003A3 (sk) | 2004-02-03 |
MY136683A (en) | 2008-11-28 |
RU2307651C2 (ru) | 2007-10-10 |
PT1397128E (pt) | 2007-09-03 |
HK1064036A1 (en) | 2005-01-21 |
DK1397128T3 (da) | 2007-10-15 |
EP1397128B1 (de) | 2007-07-04 |
ZA200308600B (en) | 2004-09-13 |
JP2004525165A (ja) | 2004-08-19 |
HUP0303910A2 (hu) | 2004-03-29 |
CA2443019A1 (en) | 2002-10-17 |
CZ20032899A3 (cs) | 2004-06-16 |
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Legal Events
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1064036 Country of ref document: HK |
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C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
ASS | Succession or assignment of patent right |
Owner name: DIOGA PHARMACEUTICAL COMPANY Free format text: FORMER OWNER: MERCK PATENT GMBH Effective date: 20070727 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20070727 Address after: American California Patentee after: Merck Patent GmbH Address before: Darmstadt Patentee before: Merck Patent GmbH |
|
C17 | Cessation of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20060809 Termination date: 20100313 |