CN1492928A - 细胞增殖因子Fwap10576 - Google Patents

细胞增殖因子Fwap10576 Download PDF

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Publication number
CN1492928A
CN1492928A CNA02805508XA CN02805508A CN1492928A CN 1492928 A CN1492928 A CN 1492928A CN A02805508X A CNA02805508X A CN A02805508XA CN 02805508 A CN02805508 A CN 02805508A CN 1492928 A CN1492928 A CN 1492928A
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CN
China
Prior art keywords
polypeptide
polynucleotides
dna
minutes
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CNA02805508XA
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English (en)
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CN1231584C (zh
Inventor
惠汝太
刘玉清
刘宝华
陆立鹤
陈敬洲
侯丽波
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fuwai Cardiovascular Disease Hospital of CAMS and PUMC
Fuwai Hospital of CAMS and PUMC
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Fuwai Hospital of CAMS and PUMC
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Publication of CN1492928A publication Critical patent/CN1492928A/zh
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Publication of CN1231584C publication Critical patent/CN1231584C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4705—Regulators; Modulating activity stimulating, promoting or activating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

本发明公开了细胞增殖因子Fwap10576多肽和编码这种多肽的多核苷酸。本发明也公开了用重组技术生产Fwap10576多肽的方法和针对这种多肽的抗体和拮抗剂。本发明还公开了含有Fwap10576多肽的药物组合物以及Fwap10576在治疗心脑血管疾病等方面的用途。本发明还提供了通过检测样品中Fwap10576核酸序列中的突变，或者Fwap10576多肽含量的改变以及Fwap10576基因产物自身抗体水平的改变而进行诊断和测定的方法。本发明的细胞增殖因子是人类来源的。

Description

PCT国内申请，说明书已公开。

Claims (1)

  1. PCT国内申请，权利要求书已公开。
CNB02805508XA 2001-02-28 2002-02-28 细胞增殖因子Fwap10576 Expired - Fee Related CN1231584C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN01109261A CN1373217A (zh) 2001-02-28 2001-02-28 细胞增殖因子Fwap10576
CN01109261.0 2001-02-28

Publications (2)

Publication Number Publication Date
CN1492928A true CN1492928A (zh) 2004-04-28
CN1231584C CN1231584C (zh) 2005-12-14

Family

ID=4657825

Family Applications (2)

Application Number Title Priority Date Filing Date
CN01109261A Pending CN1373217A (zh) 2001-02-28 2001-02-28 细胞增殖因子Fwap10576
CNB02805508XA Expired - Fee Related CN1231584C (zh) 2001-02-28 2002-02-28 细胞增殖因子Fwap10576

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CN01109261A Pending CN1373217A (zh) 2001-02-28 2001-02-28 细胞增殖因子Fwap10576

Country Status (2)

Country Link
CN (2) CN1373217A (zh)
WO (1) WO2002068639A1 (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6877550B2 (ja) * 2016-12-22 2021-05-26 ヴェンタナ メディカル システムズ， インク． 組織試料用の全自動核酸抽出方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL111181A0 (en) * 1993-10-06 1994-12-29 Univ Florida Stem cell proliferation factor, its preparation, purification and uses
CN1326973A (zh) * 2000-06-07 2001-12-19 上海博德基因开发有限公司 一种新的多肽——人层粘连蛋白γ3链(LAMC3)69.85和编码这种多肽的多核苷酸

Also Published As

Publication number Publication date
CN1231584C (zh) 2005-12-14
CN1373217A (zh) 2002-10-09
WO2002068639A1 (fr) 2002-09-06

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CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20051214

Termination date: 20130228