CN1456206A - Qi-blood tonifying capsule - Google Patents

Qi-blood tonifying capsule Download PDF

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Publication number
CN1456206A
CN1456206A CN 03118414 CN03118414A CN1456206A CN 1456206 A CN1456206 A CN 1456206A CN 03118414 CN03118414 CN 03118414 CN 03118414 A CN03118414 A CN 03118414A CN 1456206 A CN1456206 A CN 1456206A
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CN
China
Prior art keywords
radix
poria
angelicae sinensis
capsule
atractylodis macrocephalae
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN 03118414
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Chinese (zh)
Inventor
罗国仕
冯凌鹏
黄莹
杨铎
杜林辉
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SANGHAI PHARMACEUTICAL FACTORY NANCHANG JIANGXI
Original Assignee
SANGHAI PHARMACEUTICAL FACTORY NANCHANG JIANGXI
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Publication date
Application filed by SANGHAI PHARMACEUTICAL FACTORY NANCHANG JIANGXI filed Critical SANGHAI PHARMACEUTICAL FACTORY NANCHANG JIANGXI
Priority to CN 03118414 priority Critical patent/CN1456206A/en
Publication of CN1456206A publication Critical patent/CN1456206A/en
Pending legal-status Critical Current

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Abstract

A Chinese medicine in the form of capsule for reinforcing vital energy, nourishing blood, and treating menoxenia is prepared from 9 Chinese-medicinal materials including motherwort, liquorice root, Chinese angelica root, white peony root, etc.

Description

A kind of capsule that fills blood
Technical field
The present invention relates to a kind of capsule that fills blood, especially a kind of capsule that is used for women's QI and blood deficiency, menoxenia.
Background technology
The women is poor because of health, QI and blood is not prosperous, often causes QI and blood deficiency, and is weak unable, and menoxenia influences work, influences family harmony.
Summary of the invention
Purpose of the present invention just provides the capsule that fills blood of a kind of women's of treatment QI and blood deficiency, menoxenia.
The present invention is achieved like this, the main weight ratio that reaches of its prescription is: Herba Leonuri 270-275, Radix Codonopsis 65-70, Rhizoma Atractylodis Macrocephalae 65-70, Poria 65-70, Radix Glycyrrhizae 30-35, Radix Angelicae Sinensis 135-140, Radix Paeoniae Alba 65-70, Rhizoma Chuanxiong 65-70, Radix Rehmanniae Preparata 135-140, and its preparation method is: the Poria and the Radix Paeoniae Alba of 1/3 weight are ground into coarse powder; Radix Angelicae Sinensis, Rhizoma Chuanxiong, the Rhizoma Atractylodis Macrocephalae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected, and is standby; The Poria of medicinal residues and Herba Leonuri, Radix Codonopsis, Radix Rehmanniae Preparata and remaining 2/3 weight decocts with water twice, and twice decocting liquid merged, and filters, aqueous solution after filtrate and the above-mentioned distillation merges, and to be concentrated into relative density be 1.25-1.30 (60 ℃), adds above-mentioned coarse powder, stir evenly, 80-90 ℃ of oven dry, pulverize, add appropriate amount of starch, sieve, mixing is used 90% alcohol granulation, drying sprays into from Radix Angelicae Sinensis, the volatile oil that extracts in Rhizoma Chuanxiong, the Rhizoma Atractylodis Macrocephalae, sealing incapsulates.
The present invention is a capsule, and content is dark-brown granule and powder, feeble QI perfume (or spice), mildly bitter flavor, show underage rat is had improve estrogen level and the effect that increases uterus weight in the blood by animal experiment, rat anemia model is had the effect that improves RBC number and content of hemoglobin.On function, have the effect that fills blood, transfers menstruation, cure mainly women's QI and blood deficiency, weak unable, symptoms such as menoxenia.
The specific embodiment
Take by weighing Herba Leonuri 273g by the component weight ratio, Radix Codonopsis 68g, Rhizoma Atractylodis Macrocephalae 68g, Poria 68g, Radix Glycyrrhizae 34g, Radix Angelicae Sinensis 137g, Radix Paeoniae Alba 68g, Rhizoma Chuanxiong 68g, Radix Rehmanniae Preparata 137g, the Poria 22.5g and the Radix Paeoniae Alba are ground into coarse powder, standby, with Radix Angelicae Sinensis, Rhizoma Chuanxiong, the Rhizoma Atractylodis Macrocephalae is put into the distillator distillation, extract volatile oil, aqueous solution after distillation device is in addition collected standby, medicinal residues and Herba Leonuri, Radix Codonopsis, Radix Glycyrrhizae, Radix Rehmanniae Preparata and remaining 45.5g Poria decoct with water twice, decocted 2 hours for the first time, decocted 1.5 hours for the second time, twice decocting liquid merged, filter, aqueous solution after filtrate and the distillation merges, and being concentrated into relative density is 1.28 (60 ℃), adds above-mentioned coarse powder and stirs evenly, 80-90 ℃ of oven dry, pulverize, add appropriate amount of starch, sieve, mixing is with 90% ethanol pelletize, dry, spray into above-mentioned volatile oil (in advance with an amount of dehydrated alcohol dilution), sealing, incapsulate.
The BAZHEN YIMU JIAONANG that adopts above prescription and preparation technology to obtain is sent the checking of Changsha the 4th hospital clinical, and the result is as follows: one, case ordinary circumstance
45 routine deficiency of both QI and blood menoxenia patients (hypomenorrhea 19 examples, delayed menstrual cycle 8 examples, menostaxis 18 examples), 30 examples derive from clinic case, and 15 examples derive from inpatient, and ordinary circumstance sees Table 1
Table 1
Group example number Age (year) course of disease (year)
Minimax X ± SD the shortest the longest X ± SD
Open group 45 ?38????18???????28.47±5.88??10????0.25??1.58±1.72
Two, medicine and observational technique
All (Provincial Medicine Research Institute Chinese medicine institute Drug Manufacturing Room provide lot number to the clothes BAZHEN YIMU JIAONANG: 940411) 9 of every days (being roughly equal to crude drug 8.28 grams), divide and take for three times.Be a menstrual cycle (began to take in first day in passing through, serve on 15 days then stop using) one course of treatment.Observe two courses of treatment continuously, single blind method is observed.Inactive other related drugs of viewing duration and therapy.After finishing the course of treatment, outpatient service or communication are followed up a case by regular visits to and are imitated to judge the course of treatment March.Three, curative effect judging standard (according to the new clinical research guideline of Chinese medicine)
(1) clinical cure: treat the back menstrual cycle, recover normal through amount, menstrual period, 3 menstrual cycle of drug withdrawal recur, and the symptom total mark reduces more than 91% before the treatment.
(2) produce effects: treatment back menstrual cycle returned to 28 ± 7 days, and hypomenorrhea person increases by 1/3 before amount is than treatment, return to menstrual period in 7 days.3 menstrual cycle of drug withdrawal do not have recurrence.The symptom total mark reduces 70%~91% before the treatment.
(3) effective: as treatment back menstrual cycle, to improve the minimizing 35%~69% before the treatment of symptom total mark before the treatment through amount, menstrual period.
(4) invalid: treat the back menstrual cycle, do not have improvement through amount, menstrual period, the symptom total mark reduces<35% than treatment is preceding.Four, result and analysis
(1), clinical total effects
BAZHEN YIMU JIAONANG treatment uncomfortable patient of the deficiency of both QI and blood moon behind 1,2 menstrual cycle and the total effective rate after following up a case by regular visits to 3 months (obvious effective rate) be respectively 66.7% (20%) 91.1% (77.8) 100 (95.5%) and see Table 2.

Claims (2)

1, a kind of capsule that fills blood, its fill a prescription main component and weight ratio are: Herba Leonuri 270-275, Radix Codonopsis 65-70, Rhizoma Atractylodis Macrocephalae 65-70, Poria 65-70, Radix Glycyrrhizae 30-35, Radix Angelicae Sinensis 135-140, Radix Paeoniae Alba 65-70, Rhizoma Chuanxiong 65-70, Radix Rehmanniae Preparata 135-140.
2, the capsule that fills blood according to claim 1, its preparation method is: the Poria and the Radix Paeoniae Alba of 1/3 weight are ground into coarse powder; Radix Angelicae Sinensis, Rhizoma Chuanxiong, the Rhizoma Atractylodis Macrocephalae are extracted volatile oil, and the aqueous solution after distillation device is in addition collected, and is standby; The Poria of medicinal residues and Herba Leonuri, Radix Codonopsis, Radix Rehmanniae Preparata and remaining 2/3 weight decocts with water twice, and twice decocting liquid merged, and filters, aqueous solution after filtrate and the above-mentioned distillation merges, and to be concentrated into relative density be 1.25-1.30 (60 ℃), adds above-mentioned coarse powder, stir evenly, 80-90 ℃ of oven dry, pulverize, add appropriate amount of starch, sieve, mixing is used 90% alcohol granulation, drying sprays into from Radix Angelicae Sinensis, the volatile oil that extracts in Rhizoma Chuanxiong, the Rhizoma Atractylodis Macrocephalae, sealing incapsulates.
CN 03118414 2003-01-03 2003-01-03 Qi-blood tonifying capsule Pending CN1456206A (en)

Priority Applications (1)

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Application Number Priority Date Filing Date Title
CN 03118414 CN1456206A (en) 2003-01-03 2003-01-03 Qi-blood tonifying capsule

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101874852A (en) * 2010-04-28 2010-11-03 江西南昌桑海制药厂 Quality detecting method of restorex plus extract capsule
CN102579669A (en) * 2012-03-05 2012-07-18 宁夏紫荆花制药有限公司 Chinese medicinal composition for nourishing qi and blood and conditioning menstruation and preparation method thereof
CN102824457A (en) * 2012-06-04 2012-12-19 江西南昌桑海制药厂 Eight-treasure motherwort active site and preparation process of capsules
CN103989146A (en) * 2014-04-21 2014-08-20 和县鸡笼山调味品有限责任公司 Shelled shrimp chili sauce and preparation method thereof
CN104784279A (en) * 2015-05-16 2015-07-22 朱蕾 Traditional Chinese medicine composition for treating irregular menstruation
CN107412513A (en) * 2017-07-21 2017-12-01 刘道鹏 A kind of irregular menstruation tea and preparation method thereof
CN108159373A (en) * 2018-01-06 2018-06-15 明光市千里浓酒业有限公司 Corydalis tuber wine and preparation method thereof
CN111870642A (en) * 2020-08-12 2020-11-03 索绍桢 Menstruation regulating soup
CN113694039A (en) * 2020-05-21 2021-11-26 哈尔滨瀚钧现代制药有限公司 Pellet for tonifying qi and benefiting blood and preparation method thereof

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101874852A (en) * 2010-04-28 2010-11-03 江西南昌桑海制药厂 Quality detecting method of restorex plus extract capsule
CN102579669A (en) * 2012-03-05 2012-07-18 宁夏紫荆花制药有限公司 Chinese medicinal composition for nourishing qi and blood and conditioning menstruation and preparation method thereof
CN102824457A (en) * 2012-06-04 2012-12-19 江西南昌桑海制药厂 Eight-treasure motherwort active site and preparation process of capsules
CN103989146A (en) * 2014-04-21 2014-08-20 和县鸡笼山调味品有限责任公司 Shelled shrimp chili sauce and preparation method thereof
CN103989146B (en) * 2014-04-21 2015-06-10 和县鸡笼山调味品有限责任公司 Shelled shrimp chili sauce and preparation method thereof
CN104784279A (en) * 2015-05-16 2015-07-22 朱蕾 Traditional Chinese medicine composition for treating irregular menstruation
CN107412513A (en) * 2017-07-21 2017-12-01 刘道鹏 A kind of irregular menstruation tea and preparation method thereof
CN108159373A (en) * 2018-01-06 2018-06-15 明光市千里浓酒业有限公司 Corydalis tuber wine and preparation method thereof
CN113694039A (en) * 2020-05-21 2021-11-26 哈尔滨瀚钧现代制药有限公司 Pellet for tonifying qi and benefiting blood and preparation method thereof
CN111870642A (en) * 2020-08-12 2020-11-03 索绍桢 Menstruation regulating soup

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