CN1219540C - Chinese medicine for treating leukoderma and the prepn process of the tablets - Google Patents
Chinese medicine for treating leukoderma and the prepn process of the tablets Download PDFInfo
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- CN1219540C CN1219540C CN 03132315 CN03132315A CN1219540C CN 1219540 C CN1219540 C CN 1219540C CN 03132315 CN03132315 CN 03132315 CN 03132315 A CN03132315 A CN 03132315A CN 1219540 C CN1219540 C CN 1219540C
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Abstract
The present invention relates to a Chinese medicine for treating leucoderma and a method for preparing tablets thereof, which belongs to the fields of pharmaceutical products and preparing technology thereof. The present invention aims at solving the technical problem of providing a Chinese medicine for treating leukoderma and a method for preparing tablets thereof, and the Chinese medicine has the functions of harmonizing Qi and blood, nourishing livers and kidneys with reliable therapeutic effect. The present invention comprises the medicinal effect ingredients of the following weight percentages: 10% to 15% of malaytea scurfpea fruit, 10% to 15% of prepared fleeceflower root, 2% to 6% of ophiopogon root, 2% to 8% of astragalus root, 2% to 6% of white atractylodes rhizome (sauted), 2% to 6% of poria cocos wolf, 4% to 10% of rhizoma paridis, 4% to 10% of nutagrass flatsedge rhizome, 2% to 8% of atractylodes rhizome (sauted), 4% to 10% of ledebouriella root, 4% to 10% of Mohan lotus, 6% to 12% of tribulus fruit (sauted), 2% to 6% of lithospermi and 1% to 3% of liquorice root. The present invention which has the functions of harmonizing Qi and blood and nourishing livers and kidneys has a reliable therapeutic effect on leukoderma which is resulted from deficiency of Qi and blood and deficiency of livers and kidneys. The therapeutic effect is particularly obvious for young patient who is sick with a small range of leukoderma in the early time. The present invention is safe and effective for clinical use.
Description
Technical field: the present invention relates to a kind of Chinese patent medicine and manufacture method thereof, the particularly a kind of leukodermic Chinese medicine due to insufficiency of vital energy and blood, the caused by liver and kidney deficiency and preparation method of tablet thereof of being used for the treatment of.
Background technology; Vitiligo is a kind of common, posteriority depigmentation dermatoses.Motherland's medical science thinks mainly due to QI and blood deficiency, and is qi-blood disharmony or because rheumatism is strongly fragrant due to the fur.Qi-blood disharmony, blood can not the nutrition skin, and with the passing of time the deficiency of YIN must cause deficiency of both the liver and kidney, and Rong Wei does not have fluent machine, and the fur space between skin and muscles loses supports and the speckle that turns white.Its sickness rate is higher, the chronic delay of the course of disease, and treatment is difficulty relatively.
Summary of the invention; Technical problem to be solved by this invention is: a kind of have QI and blood regulating, nourishing the liver and kidney function are provided, and curative effect is treated the preparation method of leukodermic Chinese medicine and tablet thereof reliably.Its technical scheme is: the leukodermic Chinese medicine of a kind of treatment is characterized in that its composition and effectiveness and percentage by weight thereof:
Fructus Psoraleae 10-15 Radix Polygoni Multiflori Preparata 10-15 2-6 Radix Ophiopogonis Radix Codonopsis 2-8
Radix Astragali 2-6 Rhizoma Atractylodis Macrocephalae (parched) 2-6 membrane inside the rush stalk Siberian cocklebur 2-6 Rhizoma Paridis 4-10
Rhizoma Cyperi 4-10 Rhizoma Atractylodis (parched) 2-8 Radix Salviae Miltiorrhizae 4-10 Radix Saposhnikoviae 2-6
Mo Hanlian 4-10 stir-baked FRUCTUS TRIBULI 6-12 Radix Arnebiae (Radix Lithospermi) 2-6 Radix Glycyrrhizae 1-3
The preparation method of its tablet is: above-mentioned ten Six-element Chinese medicines were soaked 30 minutes, decocted twice, add 10 times of amounts of water at every turn, decocted 2 hours for the first time, decocted collecting decoction 1 hour for the second time, filter, filtrate was left standstill 12 hours, got supernatant concentration to relative density 1.25-1.28 (heat is surveyed); Vacuum drying drops into starch, Pulvis Talci, and mixing mixes granule, and compacting in flakes promptly.
Chinese medicinal tablet of the present invention adopts strengthening the body resistance, nourishing liver and kidney, and the rule of treatment of QI and blood regulating, and form in conjunction with secular clinical practice compatibility, obtained satisfied effect clinically.Its clinical research data and data are as follows:
MethodsThe cases enrolled 300 examples, diagnostic criteria is according to diagnostic criteria in the clinical trial protocol and typing standard.Curative effect determinate standard is formulated according to " new Chinese medicine treatment vitiligo clinical research guideline ".Therapeutic Method: per day for adults 3 times, each 5 (every is equivalent to crude drug 2.1-2.5g), children's looks age size clothes 3-5 sheet, and serveing on 3 months is a course of treatment, observes for 1 course of treatment.Its therapeutic outcome:
(1) clinical efficacy: produce effects (criterion is that white macula disappears more than 50%) is 38%, 114 example; Effectively (criterion be white macula disappearance person account in the 20-50% of former white macula area or the white macula have than the polychrom island) is 39.2%, 118 example; Invalid (no change or white macula enlarge before and after the treatment) is 22.6%, 68 example; Total effective rate is 77.4%, 232 example.
(2) Clinical typing curative effect: general hair style total effective rate is 60.0%, and the type total effective rate of distributing is 76.4%, and the topical type total effective rate is 86.9%, and the segmental pattern total effective rate is 82.6%.Period of expansion,, total effective rate was 81.0%, and the stable phase total effective rate is 71.1%.
(3) clinical disease course curative effect: less than the total effective rate in 1 year was 84.3%, and the total effective rate of 1-3 is 80.4%, was 67.7% greater than 3 years total effective percentage.
(4) to the microcirculatory influence of nail fold: the microcirculatory fluidised form of nail fold, color and flow velocity are all improved significantly, the microcirculation of vitiligo local lesion is had certain influence and reaches therapeutical effect.
In sum, Chinese medicinal tablet of the present invention has the function of QI and blood regulating, nourishing the liver and kidney, reliable for the vitiligo curative effect due to insufficiency of vital energy and blood, the caused by liver and kidney deficiency, especially in early days, among a small circle, little patient of age, curative effect is particularly remarkable, simultaneously the microcirculatory fluidised form of nail fold, color and flow velocity are all improved significantly, clinical safe in utilization effective, have no side effect.
The specific embodiment:
1, get Fructus Psoraleae 15kg, Radix Polygoni Multiflori Preparata 10kg, Radix Ophiopogonis 6kg, Radix Codonopsis 8kg, Radix Astragali 6kg, the Rhizoma Atractylodis Macrocephalae (stir-fry) 6kg, membrane inside the rush stalk Siberian cocklebur 6kg, Rhizoma Paridis 10kg, Rhizoma Cyperi 10kg, Rhizoma Atractylodis (stir-fry) 8kg, Radix Salviae Miltiorrhizae 10kg, Radix Saposhnikoviae 6kg, Mo Hanlian 10kg, Fructus Tribuli (stir-fry) 12kg, Radix Arnebiae (Radix Lithospermi) 6kg, Radix Glycyrrhizae 3kg, soaked 30 minutes, decoct twice, collecting decoction, filter, filtrate was left standstill 12 hours, get supernatant concentration to relative density 1.25-1.28 (heat is surveyed), vacuum drying, drop into starch 1.5kg, Pulvis Talci 1.0kg, mixing mixes granule, compacting is in blocks, and sugar coating or film-coat are promptly.
2, get Fructus Psoraleae 12kg, Radix Polygoni Multiflori Preparata 15kg, Radix Ophiopogonis 4kg, Radix Codonopsis 5.4kg, Radix Astragali 4kg, the Rhizoma Atractylodis Macrocephalae (stir-fry) 4kg, Poria 4kg, Rhizoma Paridis 6kg, Rhizoma Cyperi 8kg, Rhizoma Atractylodis (stir-fry) 5.4kg, Radix Salviae Miltiorrhizae 6kg, Radix Saposhnikoviae 4kg, Mo Hanlian 6kg, Fructus Tribuli (stir-fry) 8kg, Radix Arnebiae (Radix Lithospermi) 4kg, Radix Glycyrrhizae 2.4kg, soaked 30 minutes, decoct twice, collecting decoction, filter, filtrate was left standstill 12 hours, get supernatant concentration to relative density 1.25-1.28 (heat is surveyed), vacuum drying, drop into starch 1.5kg, Pulvis Talci 0.74kg, mixing mixes granule, compacting is in blocks, and sugar coating or film-coat are promptly.
3, get Fructus Psoraleae 10kg, Radix Polygoni Multiflori Preparata 15kg, Radix Ophiopogonis 2kg, Radix Codonopsis 4kg, the Radix Astragali, Radix Salviae Miltiorrhizae 6kg, Radix Saposhnikoviae 2kg, Mo Hanlian 6kg, Fructus Tribuli (stir-fry) 8kg, Radix Arnebiae (Radix Lithospermi) 2kg, Radix Glycyrrhizae 1kg, soaked 30 minutes, decoct twice, collecting decoction, filter, filtrate was left standstill 12 hours, got supernatant concentration to relative density 1.25-1.28 (heat is surveyed), vacuum drying, drop into starch 1.0kg, Pulvis Talci 0.7kg, mixing mixes granule, compacting is in blocks, and sugar coating or film-coat are promptly.
Claims (2)
1, the leukodermic Chinese medicine of a kind of treatment is characterized in that its composition and effectiveness and weight hundred method proportions by subtraction thereof:
Fructus Psoraleae 10-15 Radix Polygoni Multiflori Preparata 10-15 2-6 Radix Ophiopogonis Radix Codonopsis 2-8
Radix Astragali 2-6 Rhizoma Atractylodis Macrocephalae (parched) 2-6 membrane inside the rush stalk Siberian cocklebur 2-6 Rhizoma Paridis 4-10
Rhizoma Cyperi 4-10 Rhizoma Atractylodis (parched) 2-8 Radix Salviae Miltiorrhizae 4-10 Radix Saposhnikoviae 2-6
Mo Hanlian 4-10 stir-baked FRUCTUS TRIBULI 6-12 Radix Arnebiae (Radix Lithospermi) 2-6 Radix Glycyrrhizae 1-3.
2, treat the preparation method of leukodermic Chinese medicinal tablet according to claim 1, it is characterized in that: above-mentioned ten Six-element Chinese medicines were soaked 30 minutes, decocted twice, add 10 times of amounts of water at every turn, decocted 2 hours for the first time, decocted 1 hour for the second time, collecting decoction filters, and filtrate was left standstill 12 hours, get supernatant concentration to relative density 1.25-1.28, vacuum drying drops into starch, Pulvis Talci, mixing, mix granule, compacting in flakes.
Priority Applications (1)
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CN 03132315 CN1219540C (en) | 2003-08-11 | 2003-08-11 | Chinese medicine for treating leukoderma and the prepn process of the tablets |
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CN 03132315 CN1219540C (en) | 2003-08-11 | 2003-08-11 | Chinese medicine for treating leukoderma and the prepn process of the tablets |
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CN1486716A CN1486716A (en) | 2004-04-07 |
CN1219540C true CN1219540C (en) | 2005-09-21 |
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CN 03132315 Expired - Lifetime CN1219540C (en) | 2003-08-11 | 2003-08-11 | Chinese medicine for treating leukoderma and the prepn process of the tablets |
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Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN100352479C (en) * | 2004-12-29 | 2007-12-05 | 韩石蕊 | Medicament for treating leucoderma and prepartion method |
CN110841015A (en) * | 2019-12-10 | 2020-02-28 | 符强 | Pharmaceutical formulation for treating leucoderma |
CN112472766A (en) * | 2020-12-11 | 2021-03-12 | 合肥华润神鹿药业有限公司 | Preparation process and detection method of radix salviae miltiorrhizae and blood slices |
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Address after: Peach Industrial Park, economic and Technological Development Zone 231202 Anhui city in Hefei Province, Hefei SHANGPAI Highway No. 12 Patentee after: HEFEI CHINA RESOURCES SHENLU PHARMACEUTICAL CO.,LTD. Address before: The 230031 Hefei Road, Anhui province No. 190 Patentee before: Hefei Divine Deer Double-Crane Pharmaceutical Co.,Ltd. |
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Granted publication date: 20050921 |
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