CN103520588B - A kind of drug rehabilitation herbal composite - Google Patents

Abstract

The present invention discloses a kind of drug rehabilitation herbal composite, becomes with weight part numeral system by following herbal raw material: gynostemma pentaphylla 30-100 part, Radix Astragali 30-50 part, Radix Glycyrrhizae 30-60 part, Rhizome of Fortune's Drynaria 25-35 part, psyllium 20-40 part and Rhizome of Glabrous Greenbrier 20-60 part. This herbal medicine has help health, recovers effect of internal organs physiological function, can strengthen the body resistance to consolidate the constitution, be healthy and strong and cure the wound, again can detoxication and toxicant eliminating function. This herbal composite is pure Chinese medicinal preparation, nontoxic, has no side effect, safe and reliable, after drug addict is taken medicine, can suppress drug addiction very soon, and gives up very fast, and evident in efficacy, relapse rate is low, has good economic benefit and social benefit.

Description

A kind of drug rehabilitation herbal composite

Technical field

The invention belongs to medical art, it relates to a kind of herbal composite, especially a kind of drug rehabilitation herbal composite.

Background technology

Drugs not only endanger health, the Mental health of smoker, and have injured family's wellbeing with peaceful, and even society is stable, and therefore, the prohibition of drug is global an one of task of assaulting fortified position. Various countries, forbidding narco-traffic and while sucking, are just strengthening the research and development of anti-additive medicament, for studying out the medicine can effectively rehabilitated addicts and no longer relapse. At present, the drug rehabilitation method generally adopted has two kinds: one to be artificial hard de-method, such as the binding of China or put in prison forced labor method etc., this kind of method allows patient when bearing bigger misery, dependence time autophage accumulates in the alkaloid toxin in body, when these toxin concentrations drop to make neurocyte can suppress to drugs when craving for, be namely judged to give up drug addiction. But the fact is: still have a certain amount of toxin in patient's body, and not all is given up. Owing to aforesaid method easily makes patient bear bigger misery, therefore Most patients abandons drug rehabilitation because fearing; Two is dropping drug dependence method, general employing opioid receptor agonist or antagonist, namely adopts a kind of drugs to substitute another kind of drugs, quits drug abuse by the method for tapered dosage, as: methadone, opium, Lepetan, Dihydroetorphine hydrochloride etc. Though this method avoids the deficiency that patient bears physical pain, because not suffering hardships, comparatively gladly accept concerning patient, but causing patient to produce to rely on to these medicines again, anti-additive medicament is costly, and general patient is difficult to bear in addition, drug abstainer is finally made again to relapse, and relapse rate is higher. Trace it to its cause and it is: existing method of abstention had not both thoroughly eliminated the toxin in patient's body, have ignored again and drug abstainer is implemented rehabilitation, cause and in drug addict's body, also have a certain amount of toxin, though neurocyte is forced to change into adapts to lower concentration medicine, show as stable physical function state, but under suitable inducement environment, the toxin of lower concentration, even if be also difficult to the toxin of detection with chemical means, as morphine base toxin etc. will drive inducing neural cell to produce slightly to crave for sense, easy breaks up suppression power and relapses. Herbal medicine is the medical rarity of my Chinese nation, and herbal medicine can not only be cured the disease, more can comprehensively regulating body function, strengthen body immunity, therefore, be necessary to develop new anti-additive medicament completely, meet patient demand.

The patent No. is that CN200610163837.3 discloses a kind of drug-breaking medicine, it is characterised in that be made up of the raw material of following weight part: Rhizome of Bock Greenbrier 80-150 part, radix ampelopsis 60-180 part, your blue 70-160 part, bitter Pueraria lobota 100-200 part, curcuma zedoary 70-150 part.

The patent No. is that CN200710066378.1 discloses a kind of anti-additive medicament, it is characterized in that being made up of the bulk drug of following masses part: Radix Astragali 15-30 part, Radix Angelicae Sinensis 15-25 part, bighead atractylodes rhizome 10-20 part, Herba Epimedii 15-20 part, taraxacum 10-20 part, root of Chinese wild ginger 5-10 part, Chinese ephedra 5-10 part, rhizoma zingiberis 10-20 part, Radix Glycyrrhizae 10-25 part.

The patent No. is that CN200910077697.1 discloses a kind of composition of drug-dropping medicine, and its bulk drug is made up of the medicinal material of following weight part number: cow-bezoar 1-50, Poria cocos 1-50, Spina Date Seed 1-50, Yanhusuo 1-50, Radix Rehmanniae Preparata 1-50, Ternate Pinellia 1-50, root of herbaceous peony 1-50, Huang Cen 1-50, root tuber of aromatic turmeric 1-50, Chinese ephedra 1-50, ginseng 1-50, monkshood 1-50, sea 1-30, cinnabar 1-30, polygala root 1-30, coptis 1-30, Radix Glycyrrhizae 1-30, Radix Angelicae Sinensis 1-30, root of Chinese wild ginger 1-30, cape jasmine 1-30, bighead atractylodes rhizome 1-30, Radix Astragali 1-30.

At present, although there being the research and development of a lot of anti-additive medicament, but the existing herbal medicine for quitting drug abuse mostly in various degree there is weak curative effect, take effect the defect such as slow, have much room for improvement.

Summary of the invention

The object of the present invention is for overcoming prior art Problems existing, it is provided that one take effect better, nontoxic, without drug dependence, the drug rehabilitation herbal composite of nourishing the stomach of enriching blood, strong physique, benefit mind.

The present invention is achieved by the following technical solutions:

A kind of drug rehabilitation herbal composite, is become with weight part numeral system by following herbal raw material: gynostemma pentaphylla 30-100 part, Radix Astragali 30-50 part, Radix Glycyrrhizae 30-60 part, Rhizome of Fortune's Drynaria 25-35 part, psyllium 20-40 part and Rhizome of Glabrous Greenbrier 10-60 part.

Above-described a kind of drug rehabilitation herbal composite, is become with weight part numeral system by following herbal raw material: gynostemma pentaphylla 40-50 part, Radix Astragali 35-40 part, Radix Glycyrrhizae 30-40 part, Rhizome of Fortune's Drynaria 30 parts, psyllium 30-35 part and Rhizome of Glabrous Greenbrier 30-40 part.

Above-described a kind of drug rehabilitation herbal composite, obtains by the following method: after being cleaned by raw material, drying, pulverizes into fine powder, mixes, then make pharmaceutically acceptable any formulation according to a conventional method.

Above-described one drug rehabilitation herbal composite, obtains by the following method: by raw material boiling for several times, merges decocting liquid, filter, filtrate is condensed into thick cream, dry, pulverizing, then makes pharmaceutically acceptable any formulation according to a conventional method

This drug rehabilitation pharmacological property in herbal composite employing medicine source is:

1, gynostemma pentaphylla: Latin literary fame: FiveleafGynostemmaHerb; Another name: Rhizome or herb of Fiveleaf Gynostemma, Pentapanax leschenaultii, gynostemma pentaphyllum makino, Herba Gynostemmatis etc. Main component: containing compositions such as gypenoside, multiple amino acids, polysaccharide, protein, fat, food fibre, carbohydrate, calcium, phosphorus, iron, carotene, VITMAIN B1, Lin Suanna Vitamin B2 Sodium Phosphate, nicotinic acid, vitamins C and various trace elements. Meridian distribution of property and flavor: bitter, micro-sweet; Cool in nature. Return lung; Spleen; Kidney channel. Function cures mainly: has and replenishes qi to invigorate the spleen, and preventing phlegm from forming and stopping coughing is clearing heat and detoxicating, perfects immunity system, tranquilizing by nourishing the heart, Gu sweat held back by table, and kidney tonifying Wen Yang, antifatigue, effect of anti-stress; Curing mainly body void weak, empty labor loses essence, leukopenia, hyperlipidaemia, viral hepatitis, chronic gastroenteritis, chronic tracheitis, eliminates hormone side effect, various cancer, toxic dysentery etc. Gynostemma pentaphylla is used for drug rehabilitation, can effectively improve the various symptoms of drug addict, the effect have giving consideration to both the incidental and fundamental, making short work of.

2, the Radix Astragali: Latin literary fame: Leguminosae; Another name: cotton stilbene, yellow over sixty years of age, only mulberry, another name for Sichuan Province fat, hundred, hundred absorbent cotton, Huang Can, blood is joined, people's rank etc. Main component: containing flavones, soaping agents composition. Meridian distribution of property and flavor: taste is sweet, slightly warm in nature; Return liver, spleen, lung, kidney channel. Function cures mainly: can enhancing body immunologic function, protect liver, diuresis, anti-ageing, anti-stress, step-down and anti-microbial effect more widely; Jishengshenqiwan proteinuria can be eliminated, strengthen myocardial contraction, regulate blood-sugar content. The Radix Astragali is immunity moderation function drug of first choice, cures mainly the disease of deficiency of vital energy anemia, is used for the treatment of chronic nephritis, stomach trouble, urinary calculus, senile constipation, viral myocarditis, hyperosteogeny, apoplexy sequela, hepatitis B, pulmonary heart disease etc. on clinical. The Radix Astragali can be mended clearly, for drug rehabilitation, and instant effect.

3, Radix Glycyrrhizae: Latin literary fame: Glycyrrhizae; Another name: sweet grass root, Radix Glycyrrhizae, Radix Glycyrrhizae. Main component: Potenlini, glycyrrhetinic acid etc. Meridian distribution of property and flavor: taste is sweet, property is put down, nontoxic; Return 12 warps. Function cures mainly: treating disorders in five ZANG-organs six internal organs fever and chills perverse trend, hard muscles and bones, longue meat, times strength, removing toxic substances, and clothes are made light of one's life by commiting suicide and prolonged life for a long time; Raw by purging intense heat heat, ripe use fall apart exterior cold, goes pharyngalgia, except heat symptoms caused by an exopathgen, delays healthy tendency, yin-nourishing blood, tonifying the spleen and stomach, moistening lung. Radix Glycyrrhizae is toxicide classical simply, and on clinical, for separating, nux vomica is poisoning, ginseng is poisoning, heavy metal poisoning, food poisoning etc. Radix Glycyrrhizae has air making-up and spleen enlivening, moistens the lung and relieve the cough, effect of relieving spasm to stop pain, can effectively eliminate the various symptoms of drug addict.

4, Rhizome of Fortune's Drynaria: Latin literary fame: Fortune ' sDrynariaRhizome; Another name: the broken benefit of meat, Fortune's Drynaria Rhizome, monkey ginger, Mao Jiang, drynaria baronii, delevay drynaria, rock connect ginger. Main component: containing hesperidine, oranges and tangerines element etc. Meridian distribution of property and flavor: warm in nature, bitter; Return kidney, Liver Channel. Function cures mainly: the strong bone of kidney tonifying, continues and hinders pain relieving; For lumbago due to renal deficiency, suffering from a deficiency of the kidney and rush down for a long time, tinnitus is deaf, and odontoseisis, falling winks frustrates, and injured bone controls alopecia areata outward, white purplish or white patches on the skin. " property of medicine opinion " calls Rhizome of Fortune's Drynaria " in main bone poison gas ", and modern pharmacological research discovery Rhizome of Fortune's Drynaria can prevent and treat the osteoporosis that hormone causes. Treat Streptomycin sulphate toxic reaction according to clinical report Rhizome of Fortune's Drynaria and have good effect. Visible, Rhizome of Fortune's Drynaria has very strong detoxicating functions, can effectively remove toxin in drug addict's bone for drug rehabilitation.

5, psyllium: Latin literary fame: PlantagodepressaWilld.; Another name: wheel dish, blocking the way, lichens. Main component: the moon rhinanthin, mucopolysaccharide before car, racemization-plantagoside, fatty oil etc. Meridian distribution of property and flavor: taste is sweet, light, cold nature; Return lung channel; Liver Channel; Kidney channel; Bladder warp. Function cures mainly: clearing away heat and promoting diuresis, excreting dampness antidiarrheal, and bright order, eliminates the phlegm; Main dysuria, under drenching turbid band, it is full that oedema is swollen, and summer-heat and damp rushes down dysentery, and hot eyes is hidden from view, and phlegm heat is coughed and breathed heavily. " raw herbal medicine standby will " meaning psyllium " diuresis, heat-clearing poison "; " medical center bun will " be called its " rushing down kidney, clearing away the liver-fire "; " Essentials of Materia Medica " " all profit water agent damage in order more, only this (psyllium) can separate the heat of liver and intestines, damp and hot moving back and order is clear ". Psyllium is " street cleaner " of urinary system, is also have the good medicine that antitussive and antiasthmatic eliminates the phlegm simply, and to improving, coughing of drug addict is breathed heavily, the symptom of odynuria benefits.

6, Rhizome of Glabrous Greenbrier: Latin literary fame: RhizomaSmilacisGlabrae; Another name: Limonitum, thorn umbellate pore furgus, Root-bark of Monkshoodvine etc. Main component: containing soap glycosides, tannin, resin, alkaloid, volatile oil, sugar etc. Meridian distribution of property and flavor: sweet light is flat; Return Liver Channel; Stomach warp; The spleen channel. Function cures mainly: have removing toxic substances, dehumidifying, the effect in profit joint; Curing mainly syphilis, drench turbid, muscles and bones contraction pain, beriberi, treats furunculosis, and carbuncle swells, the limbs contraction caused by scrofula, syphilis and mercury poisoning, arthralgia and myalgia. Rhizome of Glabrous Greenbrier is called as syphilis first medicine, and " Chinese medicine voluminous dictionary " is recorded: " with Rhizome of Glabrous Greenbrier 250g water decoction, controlling syphilis 30 example, result cures 27 examples; Rhizome of Glabrous Greenbrier 100g water decoction treating pointed condyloma 25 example, result is all cured. " " wind-damp dispelling, controls and have loose bowels Compendium of Material Medica meaning Rhizome of Glabrous Greenbrier for strengthening the spleen and stomach, strengthening the bones and muscles ... separate mercury poison vermilion poison. " separate scorpio poison: Rhizome of Glabrous Greenbrier, Radix Glycyrrhizae, silver flower, Herba Scutellariae Barbatae, mung bean, water decoction, extremely effectively. Modern property of medicine research finds, acute and subacute cotton carbdism is had antagonistic action by Rhizome of Glabrous Greenbrier, it is seen that Rhizome of Glabrous Greenbrier has very strong detoxicating functions.

The present invention has following advantage and positively effect:

1, this Chinese medicine composition carrys out help health with this four traditional Chinese medicine of gynostemma pentaphylla, the Radix Astragali, Rhizome of Fortune's Drynaria and Radix Glycyrrhizae, recovers internal organs physiological function, can strengthen the body resistance to consolidate the constitution, be healthy and strong and cure the wound, again can detoxication and toxicant eliminating function; The present invention also utilizes Rhizome of Glabrous Greenbrier and effect of psyllium inducing diuresis for treating stranguria syndrome, makes toxin expelling more thoroughly smooth and easy.

2, this Chinese medicine composition is pure Chinese medicinal preparation, containing any may the material of habituation again, application can not produce any new pharmacological dependence repeatedly, nontoxic, have no side effect, safe and reliable, after drug addict is taken medicine, drug addiction can be suppressed very soon, and give up very fast, evident in efficacy, relapse rate is low.

3, this traditional Chinese medicine composite source is abundant, and cost is low, has good economic benefit and social benefit.

Embodiment

Below in conjunction with specific embodiment, the present invention will be further described.

One, embodiment is prepared

Embodiment 1:

Chinese medicine material and weight number:

Gynostemma pentaphylla 30 kilograms, the Radix Astragali 30 kilograms, 30 kilograms, Radix Glycyrrhizae, Rhizome of Fortune's Drynaria 25 kilograms, psyllium 20 kilograms and Rhizome of Glabrous Greenbrier 20 kilograms.

Make by the following method: after raw material is cleaned, drying, pulverize into fine powder, cross 120 orders sieves, mix, then the method for pill processed routinely makes pill.

Embodiment 2:

Chinese medicine material and weight number:

Gynostemma pentaphylla 35 kilograms, the Radix Astragali 35 kilograms, 35 kilograms, Radix Glycyrrhizae, Rhizome of Fortune's Drynaria 30 kilograms, psyllium 30 kilograms and Rhizome of Glabrous Greenbrier 20 kilograms.

Make by the following method: by raw material clean, dry after, pulverize into fine powder, cross 120 orders sieve, mix, then the method for film-making agent routinely makes tablet.

Embodiment 3:

Chinese medicine material and weight number:

Gynostemma pentaphylla 40 jin, the Radix Astragali 40 jin, 40 jin, Radix Glycyrrhizae, Rhizome of Fortune's Drynaria 30 jin, psyllium 35 jin and Rhizome of Glabrous Greenbrier 25 jin.

Make by the following method: after raw material is cleaned, drying, pulverize into fine powder, cross 120 orders sieves, mix, then the method for glue capsule routinely makes capsule.

Embodiment 4:

Chinese medicine material and weight number:

Gynostemma pentaphylla 50 jin, the Radix Astragali 40 jin, 40 jin, Radix Glycyrrhizae, Rhizome of Fortune's Drynaria 30 jin, psyllium 35 jin and Rhizome of Glabrous Greenbrier 30 jin.

Make by the following method: raw material is added 6 times soak by water 1-2 hour, overanxious, consider the slag times soak by water that adds 6 and repeat to decoct and boil 1 time, merge decocting liquid, filter, filtrate is condensed into thick cream, the method for film-making agent makes tablet routinely.

Embodiment 5:

Chinese medicine material and weight number:

Gynostemma pentaphylla 80 grams, the Radix Astragali 50 grams, 50 grams, Radix Glycyrrhizae, Rhizome of Fortune's Drynaria 35 grams, psyllium 35 grams and Rhizome of Glabrous Greenbrier 40 grams.

Make by the following method: raw material is added 8 times soak by water 2 hours, overanxious, consider the slag times soak by water that adds 6 and repeat to decoct and boil 1 time, merge decocting liquid, filter, filtrate is condensed into thick cream, dry, pulverize, the method for pill processed makes pill routinely.

Embodiment 6:

Chinese medicine material and weight number:

Gynostemma pentaphylla 100 grams, the Radix Astragali 50 grams, 60 grams, Radix Glycyrrhizae, Rhizome of Fortune's Drynaria 35 grams, psyllium 40 grams and Rhizome of Glabrous Greenbrier 60 grams.

Making by the following method: times 60% alcohol steep that adds 8 by raw material 6 hours, filter, filter residue adds 6, and times 60% ethanol repeats lixiviate 5 hours, merges vat liquor, precipitation, filters, filtrate is condensed into thick cream, dry, pulverize, and the method for glue capsule makes capsule routinely. Recovery ethanol is reused.

Two, trial effect

1, trier:

Total on probation drug addict 50 example, classical symptom is: yawn, runny nose, insomnia, anxiety, palpitaition, the whole body is uncomfortable, close that joint is ached, Nausea and vomiting etc. The wherein male sex 38 example, women 12 example, the oldest person 56 years old, the age minimum person 20 years old, drug abuse history is the longest 20 years, and the shortest half a year, consume illegal drugs mostly is heroine, and the mode of sucking has oral, snuffing and injection.

2, criterion of therapeutical effect:

(1) fully recovering: symptom completely dissolve, every index is normal, antisecosis;

(2) effective: main symptom alleviates, muscle power part is recovered;

(3) invalid: symptom does not alleviate, poor physical capacity.

3, methods for the treatment of:

50 example drug addicts are treated, adopt embodiment of the present invention traditional Chinese medicine composition for treating, three times on the one for oral administration, the all generations of every patient to drugs when craving for sense, add again and take once, analogize with this, add after taking medicine once, crave for sense can be suppressed, and disappear gradually, within seven days, be a course for the treatment of, drug addiction can be given up by emptying toxin in general two courses for the treatment of that is 14 days, first course for the treatment of is the toxin expelling phase. the 2nd course for the treatment of is thorough cleaning toxin phase, to drug abuse history length or drug addiction is heavier or the thin weak person of subjective will, should take and be consolidated three courses for the treatment of. Due to the medicine of the present invention there is decomposition, neutralize, disappear long-pending, and change effect of toxin, cell is made to produce fierce motion and consume a large amount of moisture content and certain nutrient, therefore, during treating, the reaction of patient's dry is more outstanding, it is relatively obvious that spirit is not good enough, and for this reason, curee should not restrain appetite and should drink more water, eat fruit, vegetables, reinforcement nutrition more. When toxin is discharged in a large number, there will be frequent micturition just rare phenomenon, when toxin thoroughly arrange by after, symptom disappears, and physical recovery is healthy. Neural thinking, physical state etc. be not by the impact of anti-additive medicament, and on the contrary, the damage suffered by some health flesh energy of consume illegal drugs phase is also had certain healing effect by this drug-breaking medicine.

4, result for the treatment of:

(1) treat the male sex 38 example, treat and always have efficiency to be 81.6% after 14 days, treat and always have efficiency to be 89.5% after 21 days, treat and always have efficiency to be 94.7% after 30 days, 2 examples of failing to respond to any medical treatment.

(2) treat women 12 example, treat and always have efficiency to be 75.0% after 14 days, treat and always have efficiency to be 83.3% after 21 days, treat and always have efficiency to be 91.7% after 30 days, 1 example of failing to respond to any medical treatment.

5, model case:

Deng, man, 48 years old, Guangxi people from Nanning City, drug abuse history 20 years. 2011 once because the treatment of Guangxi Red Cross hospital is lived in toxicity outbreak. Owing to the state of an illness is serious, it is arranged at intensive care unit and treats. Leave hospital because result for the treatment of is not good after 7 days. This patient speaks slurred speech, and lip is dry and cracked, lower limbs edema, lean and haggard, can not walk. Normal because of overall pain midnight disorderly cry out and disorderly cry, lose the appetite, receive difference, examined as suffering from myocarditis by hospital, pneumonia, cholecystitis, lung ponding, the diseases such as hepatitis. After taking the course for the treatment of of medicine in the embodiment of the present invention 2, above-mentioned symptom alleviates, and recovers self care ability, and has no adverse reaction, and stops medicine after the course for the treatment of of continuing to take medicine, and illness completely dissolve, does not relapse so far.

Claims (2)

1. a drug rehabilitation herbal composite, it is characterised in that: it is made up of following herbal raw material and weight:

Gynostemma pentaphylla 35 kilograms, the Radix Astragali 35 kilograms, 35 kilograms, Radix Glycyrrhizae, Rhizome of Fortune's Drynaria 30 kilograms, psyllium 30 kilograms and Rhizome of Glabrous Greenbrier 20 kilograms.

2. a kind of drug rehabilitation herbal composite according to claim 1, it is characterised in that: obtain by the following method: after raw material is cleaned, drying, pulverize into fine powder, cross 120 orders sieves, mix, then the method for film-making agent routinely makes tablet.