CN1453352A - Bacteria-free isolated operation system - Google Patents
Bacteria-free isolated operation system Download PDFInfo
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- CN1453352A CN1453352A CN 02111538 CN02111538A CN1453352A CN 1453352 A CN1453352 A CN 1453352A CN 02111538 CN02111538 CN 02111538 CN 02111538 A CN02111538 A CN 02111538A CN 1453352 A CN1453352 A CN 1453352A
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- wedge
- cabin
- bacteria
- aseptic
- free
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- 238000002474 experimental method Methods 0.000 claims abstract description 31
- 230000001954 sterilising effect Effects 0.000 claims abstract description 18
- 238000012546 transfer Methods 0.000 claims description 57
- 230000005540 biological transmission Effects 0.000 claims description 19
- 238000004659 sterilization and disinfection Methods 0.000 claims description 14
- 239000000203 mixture Substances 0.000 claims description 7
- 238000007789 sealing Methods 0.000 claims description 7
- 239000000645 desinfectant Substances 0.000 claims description 6
- 238000000889 atomisation Methods 0.000 claims description 4
- 230000008878 coupling Effects 0.000 claims description 4
- 238000010168 coupling process Methods 0.000 claims description 4
- 238000005859 coupling reaction Methods 0.000 claims description 4
- 230000007246 mechanism Effects 0.000 claims description 3
- 229920001296 polysiloxane Polymers 0.000 claims description 3
- 241001465754 Metazoa Species 0.000 abstract description 6
- 239000003814 drug Substances 0.000 abstract description 3
- 238000007689 inspection Methods 0.000 abstract description 2
- 238000004519 manufacturing process Methods 0.000 abstract description 2
- 238000000034 method Methods 0.000 description 12
- 238000000746 purification Methods 0.000 description 6
- 238000010586 diagram Methods 0.000 description 5
- 210000001503 joint Anatomy 0.000 description 4
- 238000004140 cleaning Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 230000008859 change Effects 0.000 description 2
- 230000009970 fire resistant effect Effects 0.000 description 2
- 238000012856 packing Methods 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 230000001066 destructive effect Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000009629 microbiological culture Methods 0.000 description 1
- 230000000384 rearing effect Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 238000012549 training Methods 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
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- Apparatus For Disinfection Or Sterilisation (AREA)
- Housing For Livestock And Birds (AREA)
Abstract
The bacteria-free isolated operation system consists of several bacteria-free cabinets, each of which has several sealed hand holes with operating glove, one or several sterilizing units, air circulating unit comprising blower and air filter, and power supply and control unit comprising power box and control instrument and meters. One basic bacteria-free isolated operation system consists of one bacteria-free conveying cabinet and one bacteria-free experiment cabinet with double-door isolating valve in between for bacteria-free conveyance with each bacteria-free being mounted onto a movable support. The bacteria-free isolated operation system separates the bacteria-free operation space from operating persons and outside completely, and may be used to replace available bacteria-free room for medicine inspection, medicine production, animal raising and experiment.
Description
Technical field
The present invention relates to the aseptic technique device, especially relates to a kind of device that microbial culture, animal rearing etc. need aseptic technique that is used for.
Background technology
Aseptic technique is at present generally carried out on sterilisable chamber, Bechtop, mainly is to rely on environment purification to carry out aseptic technique, and for the environment of the relative purification of building a very low range, must be to entering the air of sterilisable chamber, through just imitating.The middle effect.High efficiency filter, filter step by step, need to build a huge machine set system that involves great expense, take very big space, the running cost of whole purification system is very high, operator are subjected to multiple constraint in the sterilisable chamber operation, and strict limit movement amplitude, and are extremely inconvenient, and carrying out along with operation, the transmission of material, the degree of purification of environment is more and more lower, is difficult to keep the environment purification continuous and effective.
Chinese invention patent ZL95101842.6 discloses a kind of completely sealed aseptic manipulating system, comprises conventional containers, pipe fitting, also has flame disinfection sterile connector and cell washing filter, isolated operation suction pipe, sealed syringe; It is the various aseptic technique devices that connect and compose with pipe fitting between container, device with the flame disinfection sterile connector.The flame disinfection sterile connector is by detachable metal double valve, and contact pin and socket constitute, the fire-resistant packing ring of each interface of valve, contact pin and socket constitute, each interface of valve is adorned fire-resistant packing ring, and contact pin is sealed in a valve body afterbody by gauffer, and socket seal is contained in another valve body afterbody.This operating system system that only limits to keeps operating under the sterile state, can not carry out other aseptic technique to each parts.Each sterile device in use can't carry out disinfection and other control indexes, and its flame disinfection sterile connector complex structure, interface need to sterilize in flame, uses inconvenient.
Summary of the invention
The invention reside in the height bacteria-free isolated operation system that provides a kind of and isolate fully, can move freely, realize quick sterile transfer, continuous and effective.
A kind of bacteria-free isolated operation system is made up of several aseptic cabins, has the gloves hole and the operation gloves of several sealed on the aseptic cabin; Establish one or more sterilising systems on the aseptic cabin; Sterilising system is made up of ozonizer, ultrasonic atomizer, fan; Also can form by the disinfectant atomisation unit.Establish the air circulation system of blower fan, air filter composition on the aseptic cabin; Power supply and Controlling System that establishing electronic box and pressure, temperature, humidity, sterilization indicator control instruments are formed; System's aseptic cabin essentially consist number is two cabins, i.e. sterile transfer cabin and aseptic experiment cabin also can sterile transfer cabin and some aseptic experiments cabin supporting composition systems.The two end band transfer gates in sterile transfer cabin and transmission hatch door, the two end bands in aseptic experiment cabin transmit hatch door; Carry out the aseptic material transmission by two-door segregaion valve between described sterile transfer cabin and the aseptic experiment cabin; Aseptic cabin is placed on the traversing carriage.
Described two-door segregaion valve is made up of two portions of movable wedging, and a part is made up of fixed gate and wedge-riser flange, has the door bolt and the gate seat composition gripping mechanism that have on the fixedly gate seat and wedge-riser flange on the fixed gate; Fixed gate has the wedge tooth, and wedge-riser flange has the wedge mouth; Fixed gate one end and wedge-riser flange are hinged by door, and the other end can engage back and wedge-riser flange by door bolt to be fixed with fixing gate seat; Another part is made up of folding wedge transfer gate and folding wedge rotating cylinder, and folding wedge transfer gate and folding wedge rotating cylinder be by wedge tooth and wedge mouth wedging, the folding wedge transfer gate have can with the fixed gate wedge mouth of wedging mutually, the folding wedge rotating cylinder have can with the wedge-riser flange wedge tooth of wedging mutually; Have handle on the folding wedge rotating cylinder; Have the untie-sell with the door bolt interlock on the described wedge-riser flange, match, form locking latches with rationed marketing on being located at the folding wedge rotating cylinder; The transmission hatch door in sterile transfer cabin is connected with the folding wedge rotating cylinder, and the transmission hatch door in aseptic experiment cabin is fixedlyed connected with fixed gate.
The transmission hatch door in described sterile transfer cabin directly is connected firmly with the folding wedge rotating cylinder, also can be flexible coupling by silicone tube.
Described aseptic experiment cabin can be connected by aseptic isolation transfer device firmly with sterilizing-bucket.
System of the present invention is made up of several aseptic cabins, and adopts the two-door segregaion valve of absolute screening to match and carry out aseptic butt joint transmission, forms a height sterilized space of isolating, can move freely, realize quick sterile transfer, continuous and effective fully.But the aseptic cabin autosterilization of system of the present invention has been created 100 grades the better purifying space of being better than of dynamic continuous and effective, operator is provided isolate effectively protection fully, and operator are freed in sterilisable chamber, and operator need not frequently change working suit.System of the present invention need not huge purification system support, reduces running cost greatly.System of the present invention can arbitrarily move in general cleaning ambient, but also needs of full feeding SPF and GF level laboratory animal.
System of the present invention and traditional sterilisable chamber technology relatively have following characteristics:
| Project | The tradition sterilisable chamber | System of the present invention |
| Degree of protection to product | Relevant with operator | Protection fully |
| Degree of protection to operator | Relevant with operator | Protection fully |
| Required energy consumption | Greatly | Little |
| Material transmits | Can cause the gnotobasis variation, and relevant with operator | Guarantee under aseptic condition, to transmit fast |
| The equipment change | Sterilisable chamber is secular, and the space is occupied fully | Be easy to move dress and irrelevant with outside atmosphere |
| Mishandle causes aseptic condition destructive possibility | The technology and the training degree that depend on operator | Possibility is minimum |
| Sterilising method | The sterilization of whole room | Totally-enclosed autosterilization |
| The control of Working environment | Be difficult to control | Can be in whole process constant optimum operation environment (temperature, humidity, pressure) |
| The replacing of working suit | Every day at least three times | Do not have |
| The operation and maintenance cost | High | Low |
Bacteria-free isolated operation system of the present invention, broken through the notion of traditional " sterilisable chamber ", " clean area ", the aseptic technique space is isolated fully with the operator and the external world, the transformation of sterilisable chamber and newly-built can be replaced with settling at one go, drug inspection and production field, germ-free animal feeding system and experiment field can be widely used in.
Description of drawings
Fig. 1 is a structural representation of the present invention;
Fig. 2 is the aseptic cabin structure synoptic diagram of the present invention;
Fig. 3 is the two-door segregaion valve device of a present invention synoptic diagram;
Synoptic diagram when Fig. 4 forms sterile channel for the two-door segregaion valve of the present invention;
Fig. 5 transmits hatch door and the folding wedge rotating cylinder synoptic diagram that is flexible coupling for the present invention;
Fig. 6 is disinfection tank of the present invention and aseptic experiment cabin connection diagram.
Embodiment
As Fig. 1,2, the essentially consist of bacteria-free isolated operation system can be made up of two aseptic cabins, i.e. sterile transfer cabin 21 and aseptic experiment cabin 25.Also can form by a sterile transfer cabin 21 and several aseptic experiment cabins 25 as required.Aseptic cabin 21 and aseptic experiment cabin 25 are placed on the traversing carriage 28, and described aseptic cabin 21,25 is made by transparent material, has the gloves hole 26 and the operation gloves 25 of several sealed on the cabin; Operator only need hand is put in the cabin and can operate.
Sterilising system on the aseptic cabin can be made up of ozonizer 33, ultrasonic atomizer 39 and fan 34, also can be made up of the disinfectant atomisation unit.Air circulation system is made up of blower fan 35, air filter 31; Power supply and Controlling System are made up of switch box 38 and pressure, temperature, humidity, sterilization indicator control instruments 32 and push-switch 40.
Top, described aseptic cabin has top cover 30, guarantees the cleaning of equipment.
The two end band transfer gates 20 in sterile transfer cabin 21 and transmission hatch door 22, the two end bands in aseptic experiment cabin 25 transmit hatch door 24; Carry out aseptic connection by sterile transfer device 23 between sterile transfer cabin 21 and the aseptic experiment cabin 25.
As Fig. 3,4, two-door segregaion valve 23 is made up of two parts of movable wedging, and a part is made up of fixed gate 1 and wedge-riser flange 6, has the door bolt 3 that fixedly gate seat 2 and wedge-riser flange 6 have and the gripping mechanism of gate seat 4 compositions on the fixed gate 1; Fixed gate 1 has the wedge tooth, and wedge-riser flange 6 has the wedge mouth, and fixed gate 1 one ends and wedge-riser flange 6 are connected by door hinge 13, the other end by door bolt 3 can with after fixedly gate seat 2 engage and wedge-riser flange 6 fix.Fixed gate 1 is fixed on the transmission hatch door 24 of aseptic real Laboratory Module 25, and the combination section of fixed gate 1 and wedge-riser flange 6 makes this sterilized space airtight by 5 sealings of fixed gate sealing-ring.
Another part is made up of folding wedge transfer gate 10 and folding wedge rotating cylinder 9, folding wedge transfer gate 10 and folding wedge rotating cylinder 9 are by wedge tooth and wedge mouth wedging, folding wedge transfer gate 10 have can with the fixed gate 1 wedge mouth of wedging mutually, folding wedge rotating cylinder 9 have can with the wedge-riser flange 6 wedge tooth of wedging mutually, have handle 12 on the folding wedge rotating cylinder 9.Folding wedge rotating cylinder 9 is fixed on the transmission hatch door 22 in sterile transfer cabin 21, by 11 sealings of folding wedge rotating cylinder sealing-ring, makes this sterilized space airtight equally between folding wedge transfer gate 10 and the folding wedge rotating cylinder 9.
Have the untie-sell 8 with door bolt 3 interlocks on the wedge-riser flange 6, match, form locking latches with rationed marketing 14 on being located at folding wedge rotating cylinder 9.
When the transmission hatch door 22 in sterile transfer cabin 21 and folding wedge rotating cylinder 9 adopted direct-connected hard connection, need accurately be located the relative position in sterile transfer cabin 21 and aseptic experiment cabin 25.When sterile transfer cabin 21 and the mutual transmission of aseptic experiment cabin 25 needs article, moving two aseptic cabins matches two portions of two-door segregaion valve 23, turning handle 12, make fixed gate 1 and folding wedge transfer gate 10 wedging mutually, folding wedge rotating cylinder 9 both with folding wedge transfer gate 10 wedgings, with wedge-riser flange 6 wedging mutually,, the bacterium space that has at wedging place is isolated between fixed gate 1 and the folding wedge transfer gate 10 again by 5 sealings of fixed gate sealing-ring.Folding wedge rotating cylinder 9 and wedge-riser flange 6 be wedging mutually, by 11 sealings of folding wedge rotating cylinder sealing-ring, external environment and inner sterilized space is isolated.
After rotation is finished, rotate gate seat 4, make door bolt 3 and fixedly gate seat 2 disengagements, drive untie-sell 8 simultaneously and rotate, make it to withstand rationed marketing 14, pin folding wedge rotating cylinder 9, guarantee under the situation that door bolt 3 is opened, two spaces that have been communicated with can not guarantee that sterilized space is unlikely by bad owing to mishandle causes breaking away from.Rotary door hinge 13, fixed gate 1 drives folding wedge transfer gate 10 and opens simultaneously, forms a sterile channel between 25 two the airtight sterilized spaces in sterile transfer cabin 21 and aseptic experiment cabin.
After transmitting end, rotary door hinge 13, the fixed gate 1 that will have folding wedge transfer gate 10 is buckled on the wedge-riser flange 6, rotate gate seat 4, make door bolt 3 inject fixedly gate seat 2, untie-sell this moment 8 is rotated and is broken away from rationed marketing 14, backward rotation handle 12, by the cooperation between the wedge tooth, make folding wedge transfer gate 10 and fixed gate 1 break away from the wedge tooth of folding wedge transfer gate 10 the other sides and folding wedge rotating cylinder 9 wedgings, by 11 sealings of folding wedge rotating cylinder sealing-ring, folding wedge rotating cylinder 9 and wedge-riser flange 6 break away from, and this moment, the transmission channels of two sterilized spaces was cut off, and formed separately independently two airtight sterilized spaces.
As Fig. 5, the transmission hatch door 22 in sterile transfer cabin 21 and folding wedge rotating cylinder 9 are flexible coupling fixing by silicone tube 26 sealings, make when needing sterile transfer, and sterile transfer cabin 21 and 25 butt joints of aseptic experiment cabin are convenient, need not accurate location, operate comparatively simple with respect to hard connection.
During work, cut off passage, connection switch box 38 power supplys of two-door segregaion valve 23 earlier, start-up control instrument 32, system carries out every preparation work automatically, and temperature, humidity, the every index of pressure in the cabin are detected.When humidity is not enough in the cabin, ultrasonic atomizer 39 carries out humidification automatically, fan 34 is uniformly dispersed aqueous vapor, after humidity is up to standard, ozonizer 33 can produce ozone automatically, to sterilizing in the cabin, also can make to be full of disinfectant in the whole cabin and to sterilize by the disinfectant atomisation unit, different sterilizations requires to adopt different sterilising method and disinfectant.The air circulation system acting in conjunction that blower fan 35, air filter 31 are formed is carried out the circulating filtration cleaning to air in the cabin; Make that air purity remains on more than 100 grades in the cabin.After temperature, humidity, pressure reached automatically and sets requirement in the cabin, preparation work was finished, and promptly changes working order automatically over to,
In the operating process,, earlier the transfer gate 20 of these article by sterile transfer cabin 21 placed in the sterile transfer cabin 21 if article are delivered in the aseptic experiment cabin 25.Close sterile transfer cabin transfer gate 20 and two-door segregaion valve 23, connect power supply, start-up control instrument 32, make system carry out sterilization automatically, after reaching the appointment requirement hatch door butt joint is transmitted in two cabins, open the passage of two-door segregaion valve 23, the article sterile transfer is arrived in the aseptic experiment cabin 25, close two-door segregaion valve 23 passages, in aseptic experiment cabin 25, carry out aseptic technique.
If these article are applicable to moist heat sterilization, then these article are placed in the sterilizing-bucket 42, the outlet of sterilizing-bucket 42 is connected with two-door segregaion valve 23, close by folding wedge transfer gate 10, feed steam, after sterilization is finished, with sterilizing-bucket 42 and 25 butt joints of aseptic experiment cabin, open the sterile channel of two-door segregaion valve 23, with the article sterile transfer to aseptic experiment cabin 25.
Also can put into germ collector 30 in the aseptic experiment cabin 25, the push-switch 40 of germ collector 30 places out of my cabin, carries out the various operations of germ collector 30 in Laboratory Module 25.
Can put into animal feeding rack in the aseptic experiment cabin 25, carry out the germ-free animal raising.
Claims (8)
1. a bacteria-free isolated operation system is made up of several aseptic cabins, it is characterized in that: the gloves hole (37) and the operation gloves (36) that have several sealed on the described aseptic cabin; Described aseptic cabin is provided with one or more sterilising systems; Be provided with the air circulation system of blower fan (35), air filter (31) composition; Be provided with the power supply and the Controlling System of switch box (38) and pressure, temperature, humidity, sterilization indicator control instruments (32) composition; Described aseptic cabin is made up of a sterile transfer cabin (21) and some aseptic experiments cabin (25), the two end band transfer gates (20) of sterile transfer cabin (21) and transmission hatch door (22), and the two end bands of aseptic experiment cabin (25) transmit hatch door (24); Carry out sterile transfer by two-door segregaion valve (23) between described sterile transfer cabin (21) and aseptic experiment cabin (25); Aseptic cabin is placed on the traversing carriage (28).
2. a kind of bacteria-free isolated operation system according to claim 1 is characterized in that: described sterilising system is made up of ozonizer (33), ultrasonic atomizer (39), fan (34).
3. a kind of bacteria-free isolated operation system according to claim 1 is characterized in that: described sterilising system is made up of the disinfectant atomisation unit.
4. a kind of bacteria-free isolated operation system according to claim 1, it is characterized in that: described two-door segregaion valve (23) is made up of two portions of movable wedging, a part is made up of fixed gate (1) and wedge-riser flange (6), has the door bolt (3) and gate seat (4) the composition gripping mechanism that have on the fixedly gate seat (2) and wedge-riser flange (6) on the fixed gate (1); Fixed gate (1) has the wedge tooth, and wedge-riser flange (6) has the wedge mouth; Fixed gate (1) one end and wedge-riser flange (6) are connected by door hinge (13), and the other end can engage afterwards with fixing gate seat (2) by door bolt (3) and wedge-riser flange (6) is fixed; Another part is made up of folding wedge transfer gate (10) and folding wedge rotating cylinder (9), folding wedge transfer gate (10) and folding wedge rotating cylinder (9) are by wedge tooth and wedge mouth wedging, folding wedge transfer gate (10) have can with fixed gate (1) the wedge mouth of wedging mutually, folding wedge rotating cylinder (9) have can with wedge-riser flange (6) the wedge tooth of wedging mutually; Have handle (12) on the folding wedge rotating cylinder (9); Have the untie-sell (8) with door bolt (3) interlock on the described wedge-riser flange (6), match, form locking latches with rationed marketing (14) on being located at folding wedge rotating cylinder (9); The transmission hatch door (22) in sterile transfer cabin (21) is connected with folding wedge rotating cylinder (9), and the transmission hatch door (24) of aseptic experiment cabin (25) is fixedlyed connected with fixed gate (1).
5. a kind of bacteria-free isolated operation system according to claim 2 is characterized in that: the transmission hatch door (22) in described sterile transfer cabin (21) directly is connected firmly with folding wedge rotating cylinder (9).
6, a kind of bacteria-free isolated operation system according to claim 2 is characterized in that: the transmission hatch door (22) in described sterile transfer cabin (21) is flexible coupling by the silicone tube sealing with folding wedge rotating cylinder (9).
7, a kind of bacteria-free isolated operation system according to claim 1 is characterized in that: described aseptic experiment cabin (25) can be connected by two-door segregaion valve (23) with sterilizing-bucket (42).
8, a kind of bacteria-free isolated operation system according to claim 1 is characterized in that: described aseptic cabin (21), (25) top have top cover (30).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02111538 CN1219049C (en) | 2002-04-26 | 2002-04-26 | Bacteria-free isolated operation system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02111538 CN1219049C (en) | 2002-04-26 | 2002-04-26 | Bacteria-free isolated operation system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1453352A true CN1453352A (en) | 2003-11-05 |
| CN1219049C CN1219049C (en) | 2005-09-14 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 02111538 Expired - Fee Related CN1219049C (en) | 2002-04-26 | 2002-04-26 | Bacteria-free isolated operation system |
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| CN (1) | CN1219049C (en) |
Cited By (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101961294A (en) * | 2010-09-06 | 2011-02-02 | 上海东富龙科技股份有限公司 | Sterile isolator for lyopilization preparation core area |
| CN102328317A (en) * | 2011-09-08 | 2012-01-25 | 杭州泰林生物技术设备有限公司 | Soft cabin isolator |
| CN102599077A (en) * | 2011-01-19 | 2012-07-25 | 涩谷工业株式会社 | Sterilized connection apparatus |
| CN102827772A (en) * | 2012-09-06 | 2012-12-19 | 杭州泰林生物技术设备有限公司 | Culture medium pouring method and device |
| CN103008034A (en) * | 2011-09-26 | 2013-04-03 | 上海力申科学仪器有限公司 | Method for placement and taking out of culture object in incubator |
| CN103018069A (en) * | 2011-09-26 | 2013-04-03 | 上海力申科学仪器有限公司 | Method for taking out sample from incubator |
| CN103370409A (en) * | 2011-01-17 | 2013-10-23 | 学校法人东京女子医科大学 | Cell culture treatment system, and method for connection of modules for cell culture treatment system |
| CN103961728A (en) * | 2014-05-08 | 2014-08-06 | 苏州大学 | Transferring disinfecting device for pollutants in P3-grade biosafety cabinet |
| CN104758973A (en) * | 2015-04-03 | 2015-07-08 | 杭州泰林生物技术设备有限公司 | Isolator |
| CN104984772A (en) * | 2015-06-25 | 2015-10-21 | 中国人民解放军军事医学科学院卫生装备研究所 | Portable bio-safety inspection isolation device |
| CN106016978A (en) * | 2016-07-06 | 2016-10-12 | 山东新华医疗器械股份有限公司 | Drug sterile freeze-drying isolator system for laboratory |
| CN106926461A (en) * | 2017-04-27 | 2017-07-07 | 重庆英泰帝克科技有限公司 | A kind of aseptic printing production lines of medical 3D |
| CN107801638A (en) * | 2017-11-02 | 2018-03-16 | 深圳市前海金卓生物技术有限公司 | A kind of germfree animal carrier |
| CN107828650A (en) * | 2017-09-21 | 2018-03-23 | 浙江泰林生物技术股份有限公司 | A kind of cellular immunotherapy work station |
| CN108496831A (en) * | 2017-02-27 | 2018-09-07 | 苏州市苏杭科技器材有限公司 | Experimental animal operates apparatus sterile attachment device |
| CN109109025A (en) * | 2017-06-26 | 2019-01-01 | 天津大学 | A kind of simple anaerobic operation case |
| CN111472582A (en) * | 2020-06-23 | 2020-07-31 | 深圳市亚纪星科技有限公司 | Pathogen detection system and method for transferring pathogen |
| CN113462563A (en) * | 2021-06-24 | 2021-10-01 | 冰山松洋生物科技(大连)有限公司 | Sterile transfer system based on cell workstation and collection room UNICOM |
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2002
- 2002-04-26 CN CN 02111538 patent/CN1219049C/en not_active Expired - Fee Related
Cited By (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101961294A (en) * | 2010-09-06 | 2011-02-02 | 上海东富龙科技股份有限公司 | Sterile isolator for lyopilization preparation core area |
| US9279099B2 (en) | 2011-01-17 | 2016-03-08 | Tokyo Women's Medical University | Processing system for cell cultures and module connecting method of processing system for cell cultures |
| CN103370409B (en) * | 2011-01-17 | 2017-05-10 | 学校法人东京女子医科大学 | Cell culture treatment system, and method for connection of modules for cell culture treatment system |
| CN103370409A (en) * | 2011-01-17 | 2013-10-23 | 学校法人东京女子医科大学 | Cell culture treatment system, and method for connection of modules for cell culture treatment system |
| CN102599077A (en) * | 2011-01-19 | 2012-07-25 | 涩谷工业株式会社 | Sterilized connection apparatus |
| CN102599077B (en) * | 2011-01-19 | 2014-12-03 | 涩谷工业株式会社 | Sterilized connection apparatus |
| CN102328317A (en) * | 2011-09-08 | 2012-01-25 | 杭州泰林生物技术设备有限公司 | Soft cabin isolator |
| CN103018069A (en) * | 2011-09-26 | 2013-04-03 | 上海力申科学仪器有限公司 | Method for taking out sample from incubator |
| CN103008034A (en) * | 2011-09-26 | 2013-04-03 | 上海力申科学仪器有限公司 | Method for placement and taking out of culture object in incubator |
| CN102827772B (en) * | 2012-09-06 | 2014-04-23 | 杭州泰林生物技术设备有限公司 | Culture medium pouring method and device |
| CN102827772A (en) * | 2012-09-06 | 2012-12-19 | 杭州泰林生物技术设备有限公司 | Culture medium pouring method and device |
| CN103961728A (en) * | 2014-05-08 | 2014-08-06 | 苏州大学 | Transferring disinfecting device for pollutants in P3-grade biosafety cabinet |
| CN104758973A (en) * | 2015-04-03 | 2015-07-08 | 杭州泰林生物技术设备有限公司 | Isolator |
| CN104984772A (en) * | 2015-06-25 | 2015-10-21 | 中国人民解放军军事医学科学院卫生装备研究所 | Portable bio-safety inspection isolation device |
| CN106016978A (en) * | 2016-07-06 | 2016-10-12 | 山东新华医疗器械股份有限公司 | Drug sterile freeze-drying isolator system for laboratory |
| CN108496831A (en) * | 2017-02-27 | 2018-09-07 | 苏州市苏杭科技器材有限公司 | Experimental animal operates apparatus sterile attachment device |
| CN106926461A (en) * | 2017-04-27 | 2017-07-07 | 重庆英泰帝克科技有限公司 | A kind of aseptic printing production lines of medical 3D |
| CN109109025A (en) * | 2017-06-26 | 2019-01-01 | 天津大学 | A kind of simple anaerobic operation case |
| CN107828650A (en) * | 2017-09-21 | 2018-03-23 | 浙江泰林生物技术股份有限公司 | A kind of cellular immunotherapy work station |
| CN107828650B (en) * | 2017-09-21 | 2020-11-24 | 浙江泰林生物技术股份有限公司 | Cell immunotherapy workstation |
| CN107801638A (en) * | 2017-11-02 | 2018-03-16 | 深圳市前海金卓生物技术有限公司 | A kind of germfree animal carrier |
| CN111472582A (en) * | 2020-06-23 | 2020-07-31 | 深圳市亚纪星科技有限公司 | Pathogen detection system and method for transferring pathogen |
| CN111472582B (en) * | 2020-06-23 | 2020-11-10 | 深圳市亚纪星科技有限公司 | Pathogen detection system and method for transferring pathogen |
| CN113462563A (en) * | 2021-06-24 | 2021-10-01 | 冰山松洋生物科技(大连)有限公司 | Sterile transfer system based on cell workstation and collection room UNICOM |
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