CN1448166A - Pure natural infusion for relieving alcoholism and protecting liver and prep. thereof - Google Patents
Pure natural infusion for relieving alcoholism and protecting liver and prep. thereof Download PDFInfo
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- CN1448166A CN1448166A CN 02116419 CN02116419A CN1448166A CN 1448166 A CN1448166 A CN 1448166A CN 02116419 CN02116419 CN 02116419 CN 02116419 A CN02116419 A CN 02116419A CN 1448166 A CN1448166 A CN 1448166A
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- 208000007848 Alcoholism Diseases 0.000 title claims abstract description 10
- 201000007930 alcohol dependence Diseases 0.000 title claims abstract description 10
- 210000004185 liver Anatomy 0.000 title claims abstract description 8
- 238000001802 infusion Methods 0.000 title claims description 7
- 239000007788 liquid Substances 0.000 claims description 20
- 210000000582 semen Anatomy 0.000 claims description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 14
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 10
- 239000000706 filtrate Substances 0.000 claims description 9
- 238000002360 preparation method Methods 0.000 claims description 9
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims description 8
- 239000004375 Dextrin Substances 0.000 claims description 6
- 229920001353 Dextrin Polymers 0.000 claims description 6
- 235000019425 dextrin Nutrition 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 5
- 239000003814 drug Substances 0.000 claims description 4
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims description 3
- 229930091371 Fructose Natural products 0.000 claims description 3
- 239000005715 Fructose Substances 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 3
- 239000007779 soft material Substances 0.000 claims description 3
- 239000007921 spray Substances 0.000 claims description 3
- 239000012141 concentrate Substances 0.000 claims description 2
- 239000012467 final product Substances 0.000 claims description 2
- 238000012856 packing Methods 0.000 claims description 2
- 230000008569 process Effects 0.000 claims description 2
- 238000010298 pulverizing process Methods 0.000 claims description 2
- 239000000463 material Substances 0.000 claims 1
- 210000002784 stomach Anatomy 0.000 abstract description 6
- 230000006870 function Effects 0.000 abstract description 5
- 206010019233 Headaches Diseases 0.000 abstract description 3
- 231100000869 headache Toxicity 0.000 abstract description 3
- 230000001105 regulatory effect Effects 0.000 abstract description 3
- 210000000952 spleen Anatomy 0.000 abstract description 3
- 206010041349 Somnolence Diseases 0.000 abstract description 2
- 208000002173 dizziness Diseases 0.000 abstract description 2
- 208000024891 symptom Diseases 0.000 abstract description 2
- 244000061520 Angelica archangelica Species 0.000 abstract 1
- 235000001287 Guettarda speciosa Nutrition 0.000 abstract 1
- 244000010000 Hovenia dulcis Species 0.000 abstract 1
- 235000008584 Hovenia dulcis Nutrition 0.000 abstract 1
- 244000248825 Peltandra virginica Species 0.000 abstract 1
- 235000001188 Peltandra virginica Nutrition 0.000 abstract 1
- 235000008599 Poria cocos Nutrition 0.000 abstract 1
- 244000046146 Pueraria lobata Species 0.000 abstract 1
- 235000010575 Pueraria lobata Nutrition 0.000 abstract 1
- 240000008042 Zea mays Species 0.000 abstract 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 abstract 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 abstract 1
- 206010003549 asthenia Diseases 0.000 abstract 1
- 235000005822 corn Nutrition 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 239000006049 herbal material Substances 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 230000002936 tranquilizing effect Effects 0.000 abstract 1
- 239000002994 raw material Substances 0.000 description 5
- 241000699670 Mus sp. Species 0.000 description 4
- 235000013361 beverage Nutrition 0.000 description 3
- 230000035622 drinking Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 229920006395 saturated elastomer Polymers 0.000 description 3
- 206010003084 Areflexia Diseases 0.000 description 2
- 206010047700 Vomiting Diseases 0.000 description 2
- 230000002075 anti-alcohol Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 235000013339 cereals Nutrition 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- 230000028527 righting reflex Effects 0.000 description 2
- 230000004206 stomach function Effects 0.000 description 2
- 239000003053 toxin Substances 0.000 description 2
- 231100000765 toxin Toxicity 0.000 description 2
- 240000006122 Chenopodium album Species 0.000 description 1
- 235000009344 Chenopodium album Nutrition 0.000 description 1
- 208000004930 Fatty Liver Diseases 0.000 description 1
- 241000628997 Flos Species 0.000 description 1
- 206010019708 Hepatic steatosis Diseases 0.000 description 1
- 206010019728 Hepatitis alcoholic Diseases 0.000 description 1
- 238000012449 Kunming mouse Methods 0.000 description 1
- 241000699666 Mus <mouse, genus> Species 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 240000006394 Sorghum bicolor Species 0.000 description 1
- 235000011684 Sorghum saccharatum Nutrition 0.000 description 1
- 208000007107 Stomach Ulcer Diseases 0.000 description 1
- 208000002353 alcoholic hepatitis Diseases 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 208000019425 cirrhosis of liver Diseases 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 208000010706 fatty liver disease Diseases 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 201000005917 gastric ulcer Diseases 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 208000020016 psychiatric disease Diseases 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 210000003019 respiratory muscle Anatomy 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 231100000240 steatosis hepatitis Toxicity 0.000 description 1
- 230000003867 tiredness Effects 0.000 description 1
- 208000016255 tiredness Diseases 0.000 description 1
- 239000005418 vegetable material Substances 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The sobering up and liver-protecting granule is prepared with Chinese herbal materials including Hovenia dulcis seed, orange peel, kudzu vine root, haw, corn whisker, angelica and tuckahoe, and through decoction, filtering, concentration, granulating and other steps. It has the functions of protecting liver, sobering up, regulating stomach, invigorating spleen, tranquilizing, clearing away heat and toxic matter, etc., so that it can eliminate dizziness, headache, drowsiness, asthenia and other alcoholism symptoms.
Description
Technical field
The invention belongs to the pure natural infusion for relieving alcoholism and protecting liver that derives from vegetable material, a kind of infusion for relieving alcoholism and protecting liver of producing by Chinese herbal medicine such as Semen Hoveniae (Fructus Hoveniae), Pericarpium Citri Reticulatae, Radix Puerariae, Fructus Crataegi, Stigma Maydis, Radix Angelicae Sinensis, Poria of more specifically saying so.
Background technology
As everyone knows, wine is one of human main beverage, responsible drinking, but promoting blood circulation to remove obstruction in the collateral, heart tonifying is refreshed oneself, and allaying tiredness promotes sleeping eyes, but excessive consumption of alcohol can make the alcohol user cause dizzy, the nausea and vomiting, fidgety of headache string, and hypomnesis etc. cause death when serious even because of paralysis of respiratory muscle.Drink for a long time and also can cause diseases such as mental disorder, gastric ulcer and fatty liver, alcoholic hepatitis, liver cirrhosis.For sense that alleviates or eliminate the discomfort that the back of drinking produces and the disease of bringing, in recent years, the report of existing many antialcoholic medicines and health protection food, beverage and medicine adopts as publication number CN1058907A patent application " the Antialcoholic liver-protecting oral liquid " of Semen Hoveniae, Fructus Schisandrae Chinensis, Radix Puerariae preparation; Publication number C1176819A patent application is " a kind of alcohol-decomposing beverage and preparation method thereof " that raw material is produced with Flos puerariae lobatae, Radix Schisandrae Bicoloris, Radix Glycyrrhizae, Chenopodium album etc.But the effect of separating wine product of different formulations has very big difference.
Summary of the invention
The purpose of this invention is to provide a kind of pure natural infusion for relieving alcoholism and protecting liver and preparation method thereof with functions such as liver-protecting and alcoholism-relieving, stomach function regulating spleen invigorating, refreshment and tranquilization, heat clearing away toxin expellings.
The raw material composition of alcohol-decomposing powder of the present invention and content (in parts by weight) thereof:
Radix Puerariae 4-6 part, Semen Hoveniae (Fructus Hoveniae) 8-12 part, Pericarpium Citri Reticulatae 2-3 part, Fructus Crataegi 5-7 part, Stigma Maydis 3-5 part, Poria 4-6 part.
The preparation method of alcohol-decomposing powder of the present invention comprises following process:
1. after Semen Hoveniae (Fructus Hoveniae) is soaked 2 hours, decocted 30 minutes, obtain the decocting liquid and the medicinal residues of Semen Hoveniae (Fructus Hoveniae), the weight ratio of described water and Semen Hoveniae is 5: 1;
2. the 4-5 times of water logging that Semen Hoveniae (Fructus Hoveniae), Pericarpium Citri Reticulatae, Fructus Crataegi, Stigma Maydis, Poria is mixed its weight of back adding steeped 2 hours, decocting liquid and its medicinal residues of adding the Radix Puerariae of step (1) then therein decocted 1.5-2 hour by decocting the Chinese herbal medicine conventional method, filtered, obtain filtrate for the first time, residue adds 5 times water of Chinese medicine weight again, decocts 1.5-2 hour, filters, obtain filtrate for the second time, after twice filtrate is mixed, concentrate, obtain the extractum of relative density 1.32 (54 ℃);
3. the fructose adding distil water is boiled and join after the dissolving in the extractum that step (2) makes, being modulated into relative density is the clear paste of 1.32 (36 ℃), again with Icing Sugar and dextrin mix homogeneously, slowly add in the above-mentioned clear paste then, the ethanol that sprays into concentration 70% simultaneously makes soft material, in 60 ℃ of oven dry, pulverizing, cross 10 mesh sieves, make 10 purpose grains, packing gets final product, and the weight ratio of described clear paste, Icing Sugar and dextrin is 1: 1.2: 1.8.
Electuary instructions of taking of the present invention: drink preceding or the back boiled water of drinking is taken after mixing it with water each 1-2 bag (10g/ bag).
Advantage of the present invention and effect
The present invention is according to theory of Chinese medical science, a kind of natural Chinese medicines preparation that research and development are come out on the basis of folk secret, show through clinical use result, electuary of the present invention has functions such as liver-protecting and alcoholism-relieving, stomach function regulating spleen invigorating, refreshment and tranquilization, heat clearing away toxin expelling, can promptly remove symptoms such as giddy after drunk, headache, drowsiness, weak, vomiting, without any side effects.
Investigate below by zoopery that alcohol-decomposing powder of the present invention is sobered up to mice and the influence of sobering-up functions.
Method: fit over to mouse stomach oral with Erguotou wine medicinal liquid of the present invention.
Kunming mouse, the about 17-19g of body weight is divided into 4 groups at random, 13 every group, observes going into of every mice liquor-saturated (finishing to the time of righting reflex loss from irritating stomach) and sober up the time (from righting reflex loss to the time of recovering).
The ethanol matched group is irritated stomach 0.75ml (containing 0.25ml Erguotou wine and 0.5ml normal saline) for every.
Sea king's medicinal liquid group is irritated stomach 0.75ml (containing 0.25ml strong, colourless liquor distilled from sorghum and 0.5ml sea Wang Jin cup medicinal liquid) for every, and described extra large king's medicinal liquid is the extra large Wang Jin cup medicinal liquid with antialcoholism function of sea, Shenzhen king's medicinal liquid company limited production.
Medicinal liquid group of the present invention, irritate stomach 0.75ml (containing 0.25ml Erguotou wine and 0.5ml medical liquid B of the present invention) for every and the results are shown in following table:
| Group | Matched group | Sea king's medicinal liquid group | The medical liquid B group |
| Go into liquor-saturated (min) | 6.54±4.88 | 12.00±11.78 | ??24.46±26.39 |
| P | 0.1354 | ??0.024 | |
| (min) sobers up | 298.85±57.01 | 286.08±36.05 | ??244.33±55.41 |
| P | 0.50 | ??0.0238 |
Medical liquid B of the present invention is that the relative density in the 3rd step is the clear paste of 1.32 (36 ℃).
By last table data as can be known: extra large king's medicinal liquid has and prolongs the sober up trend of time of mice drunk time and shortening, but compare its influence with matched group not remarkable, and medical liquid B of the present invention is compared with matched group and mice can be gone into 4 times of liquor-saturated time lengthening, and significantly shorten and sober up the time (P＜0.05), amplitude reaches 20%
The specific embodiment
Further specify advantage of the present invention below by embodiment.
Example 1
The raw material that this example is used: Semen Hoveniae (Fructus Hoveniae) 9kg, Radix Puerariae 5kg, Pericarpium Citri Reticulatae 2.5kg, Fructus Crataegi 6kg, Poria 5kg, Stigma Maydis 3.5kg.
Concrete preparation method:
(1) 5 times of water of adding Semen Hoveniae (Fructus Hoveniae) weight in the Semen Hoveniae (Fructus Hoveniae) soaked 2 hours, decocted then 30 minutes, obtained Semen Hoveniae (Fructus Hoveniae) decocting liquid and medicinal residues;
(2) 5 times of water of its weight of adding in Radix Puerariae, Semen Hoveniae (Fructus Hoveniae), Pericarpium Citri Reticulatae, Fructus Crataegi, Stigma Maydis, Poria mixture, soaked 2 hours, and added Semen Hoveniae decocting liquid and its medicinal residues of step (1) again, decocted 1.8 hours, filter, obtain filtrate for the first time, residue adds 5 times of water of raw material weight again, decocts 2 hours, filter, obtain filtrate for the second time, then twice filtrate is mixed, being concentrated into relative density is the extractum of 1.32 (54 ℃);
(3) fructose is added an amount of distilled water and boil in the dissolving extractum that afterwards adding step (1) makes, being modulated into relative density is the clear paste of 1.32 (36 ℃), then with Icing Sugar and dextrin mixing, slowly add above-mentioned clear paste again, spray into 70% ethanol simultaneously, make soft material, in 60 ℃ of oven dry, pulverize, cross 10 mesh sieves, make 10 purpose grains, pack, every packed amount is 10g (being equivalent to 10 gram medical material/bags), described clear paste: Icing Sugar: dextrin=1: 1.2: 1.8 (weight).
Example 2
The raw material that this example is used: Semen Hoveniae (Fructus Hoveniae) 12kg, Pericarpium Citri Reticulatae 3kg, Radix Puerariae 6kg, Fructus Crataegi 5kg, Stigma Maydis 4kg, Poria 6kg.
Preparation method is with example 1.
Claims (2)
1. a pure natural infusion for relieving alcoholism and protecting liver is characterized in that it being to be made by following materials based on weight: Radix Puerariae 4-6 part, Semen Hoveniae (Fructus Hoveniae) 8-12 part, Pericarpium Citri Reticulatae 2-3 part, Fructus Crataegi 5-7 part, Stigma Maydis 3-5 part, Poria 4-6 part.
2. the preparation method of the described pure natural infusion for relieving alcoholism and protecting liver of claim 1 comprises following process:
(1) after Semen Hoveniae (Fructus Hoveniae) is soaked 2 hours, decocted 30 minutes, obtain the decocting liquid and the medicinal residues of Semen Hoveniae (Fructus Hoveniae), the weight ratio of described water and Semen Hoveniae (Fructus Hoveniae) is 5: 1;
(2) the 4-5 times of water logging that Radix Puerariae, Pericarpium Citri Reticulatae, Fructus Crataegi, Stigma Maydis, Poria is mixed its weight of back adding steeped 2 hours, add decocting liquid and its medicinal residues of the Radix Puerariae of step (1) then therein, decocted 1.5-2 hour, filter, obtain filtrate for the first time, residue adds 5 times water of Chinese medicine weight again, decocts 1.5-2 hour, filters, obtain filtrate for the second time, after twice filtrate is mixed, concentrate, obtain the extractum of relative density 1.32 (54 ℃);
(3) the fructose adding distil water being boiled dissolving joins in the extractum that step (2) makes, being modulated into relative density is the clear paste of 1.32 (36 ℃), again with Icing Sugar and dextrin mix homogeneously, slowly add above-mentioned clear paste then, the ethanol that sprays into concentration 70% simultaneously makes soft material, in 60 ℃ of oven dry, pulverizing, cross 10 mesh sieves, make 10 purpose grains, packing gets final product, and the weight ratio of described clear paste, Icing Sugar and dextrin is 1: 1.2: 1.8.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02116419 CN1238036C (en) | 2002-04-03 | 2002-04-03 | Pure natural infusion for relieving alcoholism and protecting liver and prep. thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02116419 CN1238036C (en) | 2002-04-03 | 2002-04-03 | Pure natural infusion for relieving alcoholism and protecting liver and prep. thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1448166A true CN1448166A (en) | 2003-10-15 |
| CN1238036C CN1238036C (en) | 2006-01-25 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 02116419 Expired - Fee Related CN1238036C (en) | 2002-04-03 | 2002-04-03 | Pure natural infusion for relieving alcoholism and protecting liver and prep. thereof |
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| Country | Link |
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| CN (1) | CN1238036C (en) |
Cited By (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100361683C (en) * | 2005-12-26 | 2008-01-16 | 河南省医学科学研究所 | Chinese medicinal preparation for treating fatly liver and its preparation method |
| CN101791380A (en) * | 2010-03-17 | 2010-08-04 | 赤峰丹龙药业有限公司 | Health product for sobering up and relieving alcohol |
| CN1913910B (en) * | 2004-01-31 | 2011-02-16 | 金基英 | Composition comprising hovenia dulcis thunb. extract, lindera obtusiloba blume extract, or herbal mixture extract thereof |
| CN101574476B (en) * | 2009-05-26 | 2012-05-02 | 徐琳 | Medicinal material composition used for lowering lipid and protecting liver auxiliarily |
| CN103055189A (en) * | 2013-02-18 | 2013-04-24 | 沈惠萍 | Traditional Chinese medicine composition with antialcoholism efficacy |
| CN103372191A (en) * | 2012-04-26 | 2013-10-30 | 北京燕康科技有限公司 | Formula with effects of invigorating stomach and protecting liver and production process of formula |
| CN104041896A (en) * | 2014-06-10 | 2014-09-17 | 福州宸昌贸易有限公司 | Medicine and food homologous plant concentrated juice and preparation method thereof |
| CN104288652A (en) * | 2014-10-15 | 2015-01-21 | 圣原健康产业有限公司 | Traditional Chinese medicine composition with hangover-alleviating health care effect and preparation method and application of traditional Chinese medicine composition |
| CN104758452A (en) * | 2014-01-07 | 2015-07-08 | 黑龙江省传奇生物医药科技开发有限公司 | Illness-preventing and immunity-strengthening traditional Chinese medicine pills or granules for human body health protection and preparation method thereof |
| CN105012797A (en) * | 2015-08-05 | 2015-11-04 | 陈西连 | Traditional Chinese medicine used for alleviating hangover and preparation method thereof |
| CN105520010A (en) * | 2015-12-04 | 2016-04-27 | 重庆三零三科技有限公司 | Liver protecting and alcoholism dispelling nutritional and health-care drink |
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| CN107156573A (en) * | 2017-05-18 | 2017-09-15 | 上海醒力食品有限公司 | A kind of alcohol-decomposing beverage and preparation method thereof |
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- 2002-04-03 CN CN 02116419 patent/CN1238036C/en not_active Expired - Fee Related
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| CN101574476B (en) * | 2009-05-26 | 2012-05-02 | 徐琳 | Medicinal material composition used for lowering lipid and protecting liver auxiliarily |
| CN101791380A (en) * | 2010-03-17 | 2010-08-04 | 赤峰丹龙药业有限公司 | Health product for sobering up and relieving alcohol |
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| CN103055189B (en) * | 2013-02-18 | 2014-09-03 | 瑞安市视尚光学眼镜科技有限公司 | Traditional Chinese medicine composition with antialcoholism efficacy |
| CN104758452A (en) * | 2014-01-07 | 2015-07-08 | 黑龙江省传奇生物医药科技开发有限公司 | Illness-preventing and immunity-strengthening traditional Chinese medicine pills or granules for human body health protection and preparation method thereof |
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