Summary of the invention
The purpose of this invention is to provide a kind of pure natural infusion for relieving alcoholism and protecting liver and preparation method thereof with functions such as liver-protecting and alcoholism-relieving, stomach function regulating spleen invigorating, refreshment and tranquilization, heat clearing away toxin expellings.
The raw material composition of alcohol-decomposing powder of the present invention and content (in parts by weight) thereof:
Radix Puerariae 4-6 part, Semen Hoveniae (Fructus Hoveniae) 8-12 part, Pericarpium Citri Reticulatae 2-3 part, Fructus Crataegi 5-7 part, Stigma Maydis 3-5 part, Poria 4-6 part.
The preparation method of alcohol-decomposing powder of the present invention comprises following process:
1. after Semen Hoveniae (Fructus Hoveniae) is soaked 2 hours, decocted 30 minutes, obtain the decocting liquid and the medicinal residues of Semen Hoveniae (Fructus Hoveniae), the weight ratio of described water and Semen Hoveniae (Fructus Hoveniae) is 5: 1;
2. the 4-5 times of water logging that Radix Puerariae, Pericarpium Citri Reticulatae, Fructus Crataegi, Stigma Maydis, Poria is mixed its weight of back adding steeped 2 hours, decocting liquid and its medicinal residues of adding the Semen Hoveniae (Fructus Hoveniae) of step (1) then therein decocted 1.5-2 hour by decocting the Chinese herbal medicine conventional method, filtered, obtain filtrate for the first time, residue adds 5 times water of Chinese medicine weight again, decocts 1.5-2 hour, filters, obtain filtrate for the second time, after twice filtrate is mixed, concentrate, obtain the extractum of relative density 1.32 (54 ℃);
3. the fructose adding distil water is boiled and join after the dissolving in the extractum that step (2) makes, being modulated into relative density is the clear paste of 1.32 (36 ℃), again with Icing Sugar and dextrin mix homogeneously, slowly add in the above-mentioned clear paste then, the ethanol that sprays into concentration 70% simultaneously makes soft material, in 60 ℃ of oven dry, pulverizing, cross 10 mesh sieves, make 10 purpose grains, packing gets final product, and the weight ratio of described clear paste, Icing Sugar and dextrin is 1: 1.2: 1.8.
Electuary instructions of taking of the present invention: drink preceding or the back boiled water of drinking is taken after mixing it with water each 1-2 bag (10g/ bag).
Advantage of the present invention and effect
The present invention is according to theory of Chinese medical science, a kind of natural Chinese medicines preparation that research and development are come out on the basis of folk secret, show through clinical use result, electuary of the present invention has functions such as liver-protecting and alcoholism-relieving, stomach function regulating spleen invigorating, refreshment and tranquilization, heat clearing away toxin expelling, can promptly remove symptoms such as giddy after drunk, headache, drowsiness, weak, vomiting, without any side effects.
Investigate below by zoopery that alcohol-decomposing powder of the present invention is sobered up to mice and the influence of sobering-up functions.
Method: fit over to mouse stomach oral with Erguotou wine medicinal liquid of the present invention.
Kunming mouse, the about 17-19g of body weight is divided into 4 groups at random, 13 every group, observes going into of every mice liquor-saturated (finishing to the time of righting reflex loss from irritating stomach) and sober up the time (from righting reflex loss to the time of recovering).
The ethanol matched group is irritated stomach 0.75ml (containing 0.25ml Erguotou wine and 0.5ml normal saline) for every.
Sea king's medicinal liquid group is irritated stomach 0.75ml (containing 0.25ml strong, colourless liquor distilled from sorghum and 0.5ml sea Wang Jin cup medicinal liquid) for every, and described extra large king's medicinal liquid is the extra large Wang Jin cup medicinal liquid with antialcoholism function of sea, Shenzhen king's medicinal liquid company limited production.
Medicinal liquid group of the present invention, irritate stomach 0.75ml (containing 0.25ml Erguotou wine and 0.5ml medical liquid B of the present invention) for every and the results are shown in following table:
Group | Matched group | Sea king's medicinal liquid group | The medical liquid B group |
Go into liquor-saturated (min) | 6.54±4.88 | 12.00±11.78 | 24.46±26.39 |
P | | 0.1354 | 0.024 |
(min) sobers up | 298.85±57.01 | 286.08±36.05 | 244.33±55.41 |
P | | 0.50 | 0.0238 |
Medical liquid B of the present invention is that the relative density in the 3rd step is the clear paste of 1.32 (36 ℃).
By last table data as can be known: extra large king's medicinal liquid has and prolongs the sober up trend of time of mice drunk time and shortening, but compare its influence with matched group not remarkable, and medical liquid B of the present invention is compared with matched group and mice can be gone into 4 times of liquor-saturated time lengthening, and significantly shorten and sober up the time (P<0.05), amplitude reaches 20%
The specific embodiment
Further specify advantage of the present invention below by embodiment.
Real row 1
The raw material that this example is used: Semen Hoveniae (Fructus Hoveniae) 9kg, Radix Puerariae 5kg, Pericarpium Citri Reticulatae 2.5kg, Fructus Crataegi 6kg, Poria 5kg, Stigma Maydis 3.5kg.
Concrete preparation method:
(1) 5 times of water of adding Semen Hoveniae (Fructus Hoveniae) weight in the Semen Hoveniae (Fructus Hoveniae) soaked 2 hours, decocted then 30 minutes, obtained Semen Hoveniae (Fructus Hoveniae) decocting liquid and medicinal residues;
(2) 5 times of water of its weight of adding in Radix Puerariae, Pericarpium Citri Reticulatae, Fructus Crataegi, Stigma Maydis, Poria mixture, soaked 2 hours, and added Semen Hoveniae (Fructus Hoveniae) decocting liquid and its medicinal residues of step (1) again, decocted 1.8 hours, filter, obtain filtrate for the first time, residue adds 5 times of water of raw material weight again, decocts 2 hours, filter, obtain filtrate for the second time, then twice filtrate is mixed, being concentrated into relative density is the extractum of 1.32 (54 ℃);
(3) fructose is added an amount of distilled water and boil in the dissolving extractum that afterwards adding step (2) makes, being modulated into relative density is the clear paste of 1.32 (36 ℃), then with Icing Sugar and dextrin mixing, slowly add above-mentioned clear paste again, spray into 70% ethanol simultaneously, make soft material, in 60 ℃ of oven dry, pulverize, cross 10 mesh sieves, make 10 purpose grains, pack, every packed amount is 10g (being equivalent to 10 gram medical material/bags), described clear paste: Icing Sugar: dextrin=1: 1.2: 1.8 (weight).
Example 2
The raw material that this example is used: Semen Hoveniae (Fructus Hoveniae) 12kg, Pericarpium Citri Reticulatae 3kg, Radix Puerariae 6kg, Fructus Crataegi 5kg, Stigma Maydis 4kg, Poria 6kg.
Preparation method is with example 1.