CN107156573A - A kind of alcohol-decomposing beverage and preparation method thereof - Google Patents
A kind of alcohol-decomposing beverage and preparation method thereof Download PDFInfo
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- CN107156573A CN107156573A CN201710353616.0A CN201710353616A CN107156573A CN 107156573 A CN107156573 A CN 107156573A CN 201710353616 A CN201710353616 A CN 201710353616A CN 107156573 A CN107156573 A CN 107156573A
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- 238000002360 preparation method Methods 0.000 title claims abstract description 12
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract description 63
- 239000000463 material Substances 0.000 claims abstract description 39
- 244000046146 Pueraria lobata Species 0.000 claims abstract description 36
- 235000010575 Pueraria lobata Nutrition 0.000 claims abstract description 36
- 210000000582 semen Anatomy 0.000 claims abstract description 36
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- 239000002994 raw material Substances 0.000 claims abstract description 24
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- 239000001630 malic acid Substances 0.000 claims abstract description 22
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- 239000000284 extract Substances 0.000 claims description 32
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- 239000007788 liquid Substances 0.000 claims description 15
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- IKHGUXGNUITLKF-XPULMUKRSA-N acetaldehyde Chemical compound [14CH]([14CH3])=O IKHGUXGNUITLKF-XPULMUKRSA-N 0.000 description 2
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- RYKKQQUKJJGFMN-HVDRVSQOSA-N 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol;(2s)-5-oxopyrrolidine-2-carboxylic acid Chemical compound OC(=O)[C@@H]1CCC(=O)N1.CC1=NC=C(CO)C(CO)=C1O RYKKQQUKJJGFMN-HVDRVSQOSA-N 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
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- 235000008584 Hovenia dulcis Nutrition 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
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- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 description 1
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- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The present invention provides a kind of alcohol-decomposing beverage and preparation method thereof.The alcohol-decomposing beverage is made up of the raw material of following parts by weight：0.5~2 part of 20~40 parts of hoveniae semoveniae semen, 10~30 parts of the root of kudzu vine, 1~5 part of hawthorn, 1~5 part of dried orange peel, 30~60 parts of white granulated sugar, 1~5 part of citric acid and malic acid.It is the material of integration of drinking and medicinal herbs according to each raw material of alcohol-decomposing beverage provided by the present invention, wherein hoveniae semoveniae semen plays main function with the root of kudzu vine as monarch drug in a prescription, hawthorn and dried orange peel play synergistic function as auxiliary element, make alcohol-decomposing beverage provided by the present invention that there is very excellent dispelling effects of alcohol, the concentration of alcohol and acetaldehyde concentration in blood after drinking can be significantly reduced, so as to fast and effeciently relieve the effect of alcohol and alleviate the sense of being still drank after a night of second day, while there is good taste, and without any toxic side effect.
Description
Technical field
The present invention relates to field of food, relate more specifically to a kind of alcohol-decomposing beverage and preparation method thereof.
Background technology
In recent years, with the continuous improvement of people's living standards, China's popularity of wine and drinking amount are in rising trend, alcohol
The number of poisoning, especially acute alcoholism increases severely.Have in global disease burden 3.5% it is disabled and healthy existence be by
Drink and cause, it is consistent with unprotected sex Disease Spectrum, WHO issues in 2012《Global alcohol policy status report》Table
Bright, in the annual death toll in the whole world, the death for having nearly 4% is caused by excessive drinking, and the cause of the death of 2,500,000 people is there are about every year with indulging in
Wine is relevant.It can be seen that, excessive drinking has seriously endangered the healthy of people, or even is also possible to trigger a series of social concerns.Therefore, seek
Look for a not only science but also convenient and practical method of effectively relieving the effect of alcohol is particularly important.
It should know, during drunk, being absorbed into internal alcohol (ethanol) 95% needs by liver
To be metabolized.First ethanol it is to be converted be acetaldehyde, the process from oxidation of ethanol into acetaldehyde need by alcohol dehydrogenase (ADH,
Alcohol dehydrogenase) complete, during acetaldehyde changes into acetic acid, play catalytic action is that acetaldehyde takes off
Hydrogen enzyme (ALDH, acetaldehydedehydrogenase).Therefore, normal alcohol metabolism process is：The ethanol of intake is in stomach
Or small enteral is absorbed, and liver is transferred to after intravasation, in liver cell, effect oxygen of the ethanol through alcohol dehydrogenase (ADH)
Acetaldehyde is melted into, action breaks of the acetaldehyde again through acetaldehyde dehydrogenase (ALDH) finally resolve into carbon dioxide and water row into acetate
Go out external.The reason for for causing drunk, current main flow academic viewpoint is to think the metabolin of ethanol (acetaldehyde, formaldehyde, acetone)
It is the reason for causing drunk.Referring to following documents：Tsukamoto S,Muto T.Nagoya T,Shimamura M,Saito
T,Tainaka H.；Alcohol (1989) 24 (2) .101-108, Neil R.McGregor (2007)；Alcohol.41
(2007)469-478；Ho-Sun Lee a,Toyohi Isse b,Toshihiro Kawamoto b,Hyun Wook Baik
c,Jong Y.Park d,Mihi Yang.Food and Chemical Toxicology 58(2013)101–106。
In order to prevent and alleviate the influence drunk and brought to body, with the development of science and technology, people have developed it is a variety of
Food or medicine are used to relieve the effect of alcohol or alleviate the ill symptomses after excessive drinking, to more quickly and effectively make one from drunk shape
Waken up in state, recover consciousness or recover self-control.Although however, being worked for the chemicals such as metadoxine relieved the effect of alcohol
It hurry up, but it can produce larger side effect to liver kidney etc..And the health products produced by the plant material of integration of drinking and medicinal herbs are then substantially
Side effect will not be produced to human body, and can also realize and fast and effeciently sober up in the case of formula and prescription and dosage are rational,
Therefore the alcohol-neutralize healthy product of research and development integration of drinking and medicinal herbs has good economic value and social value.
At present, in the market occurs in that many alcohol-decomposing beverages, although most of product contains Chinese medicine and integration of drinking and medicinal herbs composition,
But dispelling effects of alcohol and taste generally reflect bad, and the effect of the final products for actually producing also lacks objectively
Checking, consumer is not universal high for the reliability of the alcohol-decomposing beverage of market today.
For example, the B of Chinese invention patent CN 103181598 disclose one kind using the root of kudzu vine, mung bean as primary raw material, it is aided with trifoliate orange
The food materials of a variety of integration of drinking and medicinal herbs of Dulcis, radix glycyrrhizae, dark plum, honeysuckle, Poria cocos, black soya bean, red bean, the alcohol-decomposing beverage being made, but should
Patent only have studied the alcohol-decomposing beverage in zoopery for alcohol levels in blood samples concentration after drinking, the activity of liver Alcohol-metabolizing enzymes,
And for causing the acetaldehyde being still drank after a night not have been reported that, and without human volunteer's experiment is carried out, actual effect needs to be investigated.
By CJ Corp. of South Korea the patent of invention CN102218096 A of China's application disclose it is a kind of with
Trifoliate orange Dulcis fruit extracting solutions, Fructus Rosae Normalis extract, roxburgh engelhardtia extractive, lotus extract and composition made from niacinamide, and report
Said composition can promote the absorption/decomposition of alcohol in vivo, be conducive to alcohol to take the photograph relieving the effect of alcohol for taker.But the patent does not have
Zoopery is carried out, does not also have the report of clinical blood ethanol, acetaldehyde concentration.
In a word, strictly speaking above-mentioned two patent applications do not carry out objective dispelling effects of alcohol checking or verify endless
Entirely, therefore, for current disintoxicating product market, make in the urgent need to developing dispelling effects of alcohol and taste good product
Effect can actually be obtained after drinking by obtaining consumer, and carry out objective dispelling effects of alcohol checking, thus obtain the letter of consumer
Rely.
The content of the invention
It is an object of the invention to provide a kind of alcohol-decomposing beverage and preparation method thereof, so that solving prior art still lacks one
Kind quickly can effectively it sober up, and in good taste, and the problem of to body disintoxicating product without any side effects.
In order to solve the above-mentioned technical problem, the present invention uses following technical scheme：
First, alcohol-decomposing beverage provided by the present invention is constituted by raw material of medicinal and edible plant, and the present inventor is by repeatedly
Research, carries out prescription and production, obtained alcohol-decomposing beverage can fast and effeciently reduce wine according to formula provided by the present invention
Alcohol concentration, improves the activity of acetaldehyde metabolic enzyme afterwards, effectively alleviates the injury that alcohol is caused to human body.
In alcohol-decomposing beverage provided by the present invention, main function is played using hoveniae semoveniae semen and the root of kudzu vine as monarch drug in a prescription.Wherein：
Hoveniae semoveniae semen is Rhamnaceae plant trifoliate orange Dulcis (Hovenia dulcis Thunb) dry mature seed, Zao Ben《Grass
Through focusing》、《Tang materia medica》、《The Decoction and Material Medica》、《Book on Chinese herbal medicine meets former disease class book on Chinese herbal medicine》、《Hospital examines》、《Herbal lease making》、《Bin Nan sheets
Grass》Etc. all just on the books, " trifoliate orange Dulcis relieving alcoholisms in medicine writings；Relieving alcoholism but product chess piece it is wonderful；Honey raisin tree is kind relieve the effect of alcohol it is remaining ... wood is
In room, room wine then taste is thin ".Trifoliate orange Dulcis platymisciums containing the composition such as saponin(e, flavones, alkaloid, with relieving alcoholism, anti peroxidation of lipid,
The multiple pharmacological effects such as liver protection, anti-hepatic fibrosis, anti-aging, antifatigue and protection central nervous system, modern study finds trifoliate orange
Dulcis can significantly reduce the concentration of alcohol in blood, improve the activity of alcohol metabolism enzyme.
The root of kudzu vine is legume pueraria lobata Pueraria lobata (Willd.) dry root, practises and claims elegant jessamine.According to《Middle Chinese
People republic pharmacopeia》One record of version in 2010, the root of kudzu vine is mild-natured, and acrid-sweet flavor is brought down a fever with expelling pathogenic factors from muscles and skin, promoted the production of body fluid to quench thirst, promoting eruption, rising Yang
Antidiarrheal, clearing and activating the channels and collaterals, effect of relieving alcoholism.Modern study shows that the root of kudzu vine has certain curative effect to acute alcoholism, and has concurrently
Reduce blood pressure, the effect of reducing heart rate, it is adaptable to the treatment of various acute alcoholism patients.
Hawthorn and dried orange peel have also been selected in more preferable dispelling effects of alcohol, alcohol-decomposing beverage of the invention as aiding in into order to reach
Point, synergistic function is mutually played with the active component for playing contained in synergistic function, this several raw material, makes institute of the present invention
The alcohol-decomposing beverage of offer has effects that the very excellent metabolism of promotion ethanol in blood and raising acetaldehyde metabolism, therefore, it is possible to fast
The sense of being still drank after a night that speed is effectively relieved the effect of alcohol and alleviated second day.
Also contain white granulated sugar, citric acid and malic acid in mouthfeel, alcohol-decomposing beverage of the invention to further improve, improve
People take the enthusiasm of the alcohol-decomposing beverage.
The consumption of the alcohol-decomposing beverage of the present invention is that inventor carries out many experiments and gropes summary and draw, each component consumption with
All there is good therapeutic effect in the range of lower parts by weight：
A kind of alcohol-decomposing beverage is provided, the alcohol-decomposing beverage is made up of the raw material of following parts by weight：20~40 parts of hoveniae semoveniae semen, the root of kudzu vine
0.5~2 part of 10~30 parts, 1~5 part of hawthorn, 1~5 part of dried orange peel, 30~60 parts of white granulated sugar, 1~5 part of citric acid and malic acid.
The consumption of each raw material can also be：20~30 parts of hoveniae semoveniae semen, 20~30 parts of the root of kudzu vine, 1~5 part of hawthorn, dried orange peel 2~5
Part, 30~50 parts of white granulated sugar, 1~5 part of citric acid and 0.5~1 part of malic acid.
Preferably, the consumption of each raw material is：20 parts of hoveniae semoveniae semen, 30 parts of the root of kudzu vine, 1 part of hawthorn, 2 parts of dried orange peel, 30 parts of white granulated sugar,
0.5 part of 1 part of citric acid and malic acid.
The consumption of each raw material can also be：30~40 parts of hoveniae semoveniae semen, 10~20 parts of the root of kudzu vine, 1~5 part of hawthorn, dried orange peel 1~5
Part, 40~60 parts of white granulated sugar, 2~5 parts of citric acid and 1~2 part of malic acid.
Preferably, the consumption of each raw material is：40 parts of hoveniae semoveniae semen, 10 parts of the root of kudzu vine, 5 parts of hawthorn, 1 part of dried orange peel, 60 parts of white granulated sugar,
2 parts of 5 parts of citric acid and malic acid.
It is further preferred that the consumption of each raw material is：30 parts of hoveniae semoveniae semen, 30 parts of the root of kudzu vine, 2.5 parts of hawthorn, 2.5 parts of dried orange peel, white sand
1 part of 30 parts of sugar, 2.5 parts of citric acid and malic acid.
The above-mentioned alcohol-decomposing beverage provided according to the present invention, it is preferable that its preparation method comprises the following steps：A) weight more than
Amount proportioning weighs hoveniae semoveniae semen, the root of kudzu vine, hawthorn, dried orange peel, cleans, with hawthorn, dried orange peel after the clean hoveniae semoveniae semen, the root of kudzu vine are crushed
It is mixed to get mixtures of materials；B) added water into the mixtures of materials, carry out first time extraction, filter to extract for the first time
Liquid；Add water, carry out second and extract, filter to obtain second of extract solution；C) the first time extract solution and second are extracted
Liquid merges, and filters, concentration, and the concentrate of solid content 30%~40% is made, standby；D) add water and add into the concentrate
Heat, weighs white granulated sugar, citric acid, malic acid respectively, stirs to being completely dissolved, add water constant volume；And e) by the feed liquid after constant volume
Filtering, sterilizing is filling, and the alcohol-decomposing beverage is made.
Preferably, in the step b), first time amount of water is 10~20 times, is extracted 1~2 hour for the first time；Second
Amount of water is 5~10 times, second of extraction 0.5~1 hour.
Preferably, the first time extracts and the second temperature extracted is 80~100 DEG C.
Preferably, added water in the step d) into the concentrate and be heated to 55~70 DEG C, add white granulated sugar, lemon
Acid, malic acid, stirring is to being completely dissolved.Preferably, 20~50min of stirring at low speed is uniform to all thawings.
According to above-mentioned alcohol-decomposing beverage for providing of the present invention and preparation method thereof, its beneficial effect compared with the prior art is such as
Under：
Each raw material is the material of integration of drinking and medicinal herbs, and wherein hoveniae semoveniae semen and the root of kudzu vine play main function as monarch drug in a prescription, hawthorn and
Dried orange peel plays synergistic function as auxiliary element, alcohol-decomposing beverage of the present invention is had very excellent dispelling effects of alcohol；
Even if when with disclosed similar disintoxicating product progress Contrast on effect in the prior art, alcohol-decomposing beverage pair of the invention
In drunk rate, 4h concentration of alcohol, 1h acetaldehyde concentrations, 2h acetaldehyde concentrations have clear improvement after drinking, and particularly drunk rate is compared to existing
Some alcohol-decomposing beverages at utmost can be reduced to 60% from 90%；
To volunteer 0.5h, 1h, 1.5h after drinking, the result that human exhaled breath's ethanol content is carried out in 2h different time sections is determined
Displaying that will be low than alcohol-decomposing beverage of the prior art, so that demonstrating the alcohol-decomposing beverage of the present invention has accelerating alcohol in people
Internal metabolism, and it is more notable than the like product effect of in the market；
It is without any side effects to human body according to the alcohol-decomposing beverage that the present invention is provided.
In a word, the invention provides a kind of concentration of alcohol and acetaldehyde concentration that can be significantly reduced in blood after drinking, so that
It can fast and effeciently relieve the effect of alcohol, and the sense of being still drank after a night of second day can be alleviated, while there is good taste, again without any toxic side effect
Alcohol-decomposing beverage.
Brief description of the drawings
Fig. 1 be the alcohol-decomposing beverage and alcohol-decomposing beverage of the prior art that provide according to a preferred embodiment of the invention for
Volunteer's internal alcohol concentration change over time after drinking and the Comparative result of influence changed.
Embodiment
Below in conjunction with specific embodiment, the present invention will be further described.It should be understood that following examples are merely to illustrate this
Invention is not for limitation the scope of the present invention.
According in alcohol-decomposing beverage provided by the present invention, each raw material is the material of integration of drinking and medicinal herbs, wherein hoveniae semoveniae semen and Pueraria lobota
Root plays main function as monarch drug in a prescription, and hawthorn and dried orange peel are used as auxiliary element synergistic function.Contained by several raw materials
Active component can play synergistic function, the alcohol-decomposing beverage that the present invention is provided is had very excellent promotion ethanol in blood
Metabolism and the effect for improving acetaldehyde metabolism, can fast and effeciently relieve the effect of alcohol, and alleviate the sense of being still drank after a night of second day.
Embodiment 1
A kind of alcohol-decomposing beverage, it is prepared from by the raw material of following parts by weight：20 parts of hoveniae semoveniae semen, 30 parts of the root of kudzu vine, hawthorn 1
Part, 2 parts of dried orange peel, 30 parts of white granulated sugar, 1 part of citric acid, 0.5 part of malic acid.
Step A, feed intake：Cleaned after first hoveniae semoveniae semen, the root of kudzu vine, dried orange peel, hawthorn are weighed standby；Hoveniae semoveniae semen, the root of kudzu vine are weighed
Mixtures of materials is mixed to get with dried orange peel, hawthorn after crushing, then mixed material is put into filter bag and put into extractor.
Step B, extraction：For the first time toward the water of 15 times of injecting material mixture in extractor, extraction 2 hours for the first time, the
After once extracting, by the mixtures of materials separation of solid and liquid in extractor, first time extract solution is filtrated to get standby；Again toward extractor
After second is extracted, the mixtures of materials in extractor is consolidated for the water of interior second of addition, 8 times of material, second of extraction 1 hour
Liquid is separated, and is filtrated to get second of extract solution standby；In the extraction process, temperature is 80 DEG C.
Step C, concentration：First time extract solution in step B and second of extract solution are merged, first through 200 mesh filter mistakes
Filter, is then concentrated, and the concentrate of solid content 40% is made, standby.
Step D, dissolving, constant volume：First water being added to dissolving tank and being heated to 55 DEG C, white granulated sugar, citric acid, apple are weighed respectively
Acid.Put into respectively according to technological process in conditioning tank, moderate-speed mixer is completely dissolved it, and the feed liquid after dissolving is pumped into constant volume tank
In.Weigh in concentrate and flavoring essence addition constant volume tank that step C is obtained, stirring at low speed 30min adds purified water constant volume
To normal volume.
It is step E, sterilizing, filling：By the feed liquid after constant volume by 300 mesh filter impurity screenings, then sterilized, filled
Dress.Beverage products of the present invention are made.
Embodiment 2
A kind of alcohol-decomposing beverage, it is prepared from by the raw material of following parts by weight：30 parts of hoveniae semoveniae semen, 20 parts of the root of kudzu vine, hawthorn 5
Part, 5 parts of dried orange peel, 40 parts of white granulated sugar, 2 parts of citric acid, 1 part of malic acid.
Step A, feed intake：Cleaned after first hoveniae semoveniae semen, the root of kudzu vine, dried orange peel, hawthorn are weighed standby；Hoveniae semoveniae semen, the root of kudzu vine are weighed
Mixtures of materials is mixed to get with dried orange peel, hawthorn after crushing, then mixed material is put into filter bag and put into extractor.
Step B, extraction：For the first time toward the water of 10 times of injecting material mixture in extractor, extraction 2 hours for the first time, the
After once extracting, by the mixtures of materials separation of solid and liquid in extractor, first time extract solution is filtrated to get standby；Again toward extractor
The water of interior second of addition, 10 times of material, second of extraction 0.5 hour, after second is extracted, by the material mixing in extractor
Thing separation of solid and liquid, is filtrated to get second of extract solution standby；In the extraction process, temperature is 80 DEG C.
Step C, concentration：First time extract solution in step B and second of extract solution are merged, first through 200 mesh filter mistakes
Filter, is then concentrated, and the concentrate of solid content 30% is made, standby.
Step D, dissolving, constant volume：First water being added to dissolving tank and being heated to 60 DEG C, white granulated sugar, citric acid, apple are weighed respectively
Acid.Put into respectively according to technological process in conditioning tank, moderate-speed mixer is completely dissolved it, and the feed liquid after dissolving is pumped into constant volume tank
In.Weigh in concentrate and flavoring essence addition constant volume tank that step C is obtained, stirring at low speed 30min adds purified water constant volume
To normal volume.
It is step E, sterilizing, filling：By the feed liquid after constant volume by 300 mesh filter impurity screenings, then sterilized, filled
Dress.Beverage products of the present invention are made.
Embodiment 3
A kind of alcohol-decomposing beverage, it is prepared from by the raw material of following parts by weight：40 parts of hoveniae semoveniae semen, 10 parts of the root of kudzu vine, hawthorn 5
Part, 1 part of dried orange peel, 60 parts of white granulated sugar, 5 parts of citric acid, 2 parts of malic acid.
Step A, feed intake：Cleaned after first hoveniae semoveniae semen, the root of kudzu vine, dried orange peel, hawthorn are weighed standby；Hoveniae semoveniae semen, the root of kudzu vine are weighed
Mixtures of materials is mixed to get with dried orange peel, hawthorn after crushing, then mixed material is put into filter bag and put into extractor.
Step B, extraction：For the first time toward the water of 20 times of injecting material mixture in extractor, extraction 2 hours for the first time, the
After once extracting, by the mixtures of materials separation of solid and liquid in extractor, first time extract solution is filtrated to get standby；Again toward extractor
The water of interior second of addition, 10 times of material, second of extraction 1 hour, after second is extracted, by the mixtures of materials in extractor
Separation of solid and liquid, is filtrated to get second of extract solution standby；In the extraction process, temperature is 100 DEG C.
Step C, concentration：First time extract solution in step B and second of extract solution are merged, first through 200 mesh filter mistakes
Filter, is then concentrated, and the concentrate of solid content 40% is made, standby.
Step D, dissolving, constant volume：First water being added to dissolving tank and being heated to 70 DEG C, white granulated sugar, citric acid, apple are weighed respectively
Acid.Put into respectively according to technological process in conditioning tank, moderate-speed mixer is completely dissolved it, and the feed liquid after dissolving is pumped into constant volume tank
In.Weigh in concentrate and flavoring essence addition constant volume tank that step C is obtained, stirring at low speed 30min adds purified water constant volume
To normal volume.
It is step E, sterilizing, filling：By the feed liquid after constant volume by 300 mesh filter impurity screenings, then sterilized, filled
Dress.Beverage products of the present invention are made.
Embodiment 4
A kind of alcohol-decomposing beverage, it is prepared from by the raw material of following parts by weight:20 parts of hoveniae semoveniae semen, 30 parts of the root of kudzu vine, hawthorn 1
Part, 5 parts of dried orange peel, 30 parts of white granulated sugar, 1 part of citric acid, 0.5 part of malic acid.
Step A, feed intake：Cleaned after first hoveniae semoveniae semen, the root of kudzu vine, dried orange peel, hawthorn are weighed standby；Hoveniae semoveniae semen, the root of kudzu vine are weighed
Mixtures of materials is mixed to get with dried orange peel, hawthorn after crushing, then mixed material is put into filter bag and put into extractor.
Step B, extraction：For the first time toward the water of 10 times of injecting material mixture in extractor, extraction 1 hour for the first time, the
After once extracting, by the mixtures of materials separation of solid and liquid in extractor, first time extract solution is filtrated to get standby；Again toward extractor
The water of interior second of addition, 5 times of material, second of extraction 0.5 hour, after second is extracted, by the mixtures of materials in extractor
Separation of solid and liquid, is filtrated to get second of extract solution standby；In the extraction process, temperature is 80 DEG C.
Step C, concentration：First time extract solution in step B and second of extract solution are merged, first through 200 mesh filter mistakes
Filter, is then concentrated, and solid content 30%-40% concentrate is made, standby.
Step D, dissolving, constant volume：First water being added to dissolving tank and being heated to 70 DEG C, white granulated sugar, citric acid, apple are weighed respectively
Acid.Put into respectively according to technological process in conditioning tank, moderate-speed mixer is completely dissolved it, and the feed liquid after dissolving is pumped into constant volume tank
In.Weigh in concentrate and flavoring essence addition constant volume tank that step C is obtained, stirring at low speed 30min adds purified water constant volume
To normal volume.
It is step E, sterilizing, filling：By the feed liquid after constant volume by 300 mesh filter impurity screenings, then sterilized, filled
Dress.Beverage products of the present invention are made.
Embodiment 5
A kind of alcohol-decomposing beverage, it is prepared from by the raw material of following parts by weight：30 parts of hoveniae semoveniae semen, 30 parts of the root of kudzu vine, hawthorn 2.5
Part, 2.5 parts of dried orange peel, 30 parts of white granulated sugar, 2.5 parts of citric acid, 1 part of malic acid.
Step A, feed intake：Cleaned after first hoveniae semoveniae semen, the root of kudzu vine, dried orange peel, hawthorn are weighed standby；Hoveniae semoveniae semen, the root of kudzu vine are weighed
Mixtures of materials is mixed to get with dried orange peel, hawthorn after crushing, then mixed material is put into filter bag and put into extractor.
Step B, extraction：For the first time toward the water of 15 times of injecting material mixture in extractor, extraction 1 hour for the first time, the
After once extracting, by the mixtures of materials separation of solid and liquid in extractor, first time extract solution is filtrated to get standby；Again toward extractor
The water of interior second of addition, 8 times of material, second of extraction 0.5 hour, after second is extracted, by the mixtures of materials in extractor
Separation of solid and liquid, is filtrated to get second of extract solution standby；In the extraction process, temperature is 90 DEG C.
Step C, concentration：First time extract solution in step B and second of extract solution are merged, first through 200 mesh filter mistakes
Filter, is then concentrated, and the concentrate of solid content 35% is made, standby.
Step D, dissolving, constant volume：First water being added to dissolving tank and being heated to 60 DEG C, white granulated sugar, citric acid, apple are weighed respectively
Acid.Put into respectively according to technological process in conditioning tank, moderate-speed mixer is completely dissolved it, and the feed liquid after dissolving is pumped into constant volume tank
In.Weigh in concentrate and flavoring essence addition constant volume tank that step C is obtained, stirring at low speed 30min adds purified water constant volume
To normal volume.
It is step E, sterilizing, filling：By the feed liquid after constant volume by 300 mesh filter impurity screenings, then sterilized, filled
Dress.Beverage products of the present invention are made.
Embodiment 6
6.1 experimental animal
ICR mouse, male, 16-18 grams, 180, purchased from Shanghai Slac Experimental Animal Co., Ltd..After animal is bought,
It is responsible for quarantining and is managed by animal doctor, quarantine is 3 days, during which general clinical observation is carried out to animal, through veterinary quarantine, 180
Animal is all qualified, is used equally for experiment.Animal feeding sets 20~26 DEG C of room temperature in cleaning grade Animal House, and humidity 40%~
70%, 12 hours light and shade alternatings of illumination.
6.2 experiment packet
Simple alcohol group：30, gavage 52% white wine l0ml/kg；Adult equivalent to 70 kg body weights disposably drinks
With 52 degree of 1000 milliliters of white wine.
Test A groups：30, beverage prepared by gavage embodiment 1, the adult equivalent to 70 kg body weights disposably drinks reality
Apply 200 milliliters of 1 beverage of example.
Test B groups：30, beverage prepared by gavage embodiment 3, the adult equivalent to 70 kg body weights disposably drinks reality
Apply 200 milliliters of 3 beverage of example.
Test C groups：30, beverage prepared by gavage embodiment 5, the adult equivalent to 70 kg body weights disposably drinks reality
Apply 200 milliliters of 5 beverage of example.
Test D groups：30, the beverage that gavage is prepared according to patent CN 103181598B, equivalent to 70 kg body weights into
People disposably drinks 200 milliliters of the beverage of patent CN 103181598B preparations.
Test E groups：30, the beverage that gavage is prepared according to patent CN102218096A, equivalent to holding for 70 kg body weights
Recognize and disposable drink patent CN102218096A and prepare 200 milliliters of beverage.
6.3 experimental method
6.3.1 formula beverage is tested to mice drunk time effects
Gavage gives corresponding test sample to each group respectively, and test sample here refers respectively to the beverage of embodiment 1, embodiment 3 and drunk
Material, the beverage of embodiment 5, the beverage prepared by CN 103181598B, the beverage prepared by patent CN102218096A, 1 times/day,
Continuous 8 days.30min after last dose, each group gives 52% alcohol with 17mL/kg dosage gavage, screens areflexia conduct
Drunk mouse is recorded and statistical analysis.Record the drunk rate of mouse of each experimental group.Drunk by being given before alcohol is given
The effect of material is animal is absorbed beverage in advance, functional component contained by beverage is reached liver, for testing the metabolism to alcohol
Effect.
6.3.2 influence of the formula beverage to the drunk rate of mouse
Every group is given after alcohol respectively, mouse upset is placed on flat board, each group mouse is filled after drinking, is observed and is recorded
The drunk quantity of mouse, tolerance time, drunk time.Mouse filled after drinking, by its dorsad under, be gently placed in mouse cage.If small
Mouse dorsad under posture keep more than 30s, then it is assumed that righting reflex loss, i.e., it is drunk, otherwise to be not liquor-saturated.
6.3.3 formula beverage is detected to mouse blood alcohol concentration influence index
Every group takes 9 mouse euthanasia respectively at giving 1h, 2h after alcohol, gathers blood, 10000 turns/min centrifugations
10min separates serum, detection ethanol in blood concentration, acetaldehyde concentration.
Every group takes remaining 12 mouse livers and blood respectively at giving 4h after alcohol, detection acetaldehyde dehydrogenase (ALDH)
Activity, 4h alcohol levels in blood samples concentration.
6.3.4 observed and recorded
During experiment, every morning and the dead or dying situation for respectively observing 1 animal afternoon, the state of mind, behavior are lived
Dynamic, breathing, secretion, situation of ingesting, stool etc..All the weight of animals are weighed every other day.
6.3.5 data statistics
Statistical method is analyzed using the statistical softwares of SPSS 21.0, the average and standard deviation of every group of data is calculated, using list
Analysis of variance is analyzed.Insolation level α=0.05.
6.4 experimental result
Carried out by the drunk rate to each group, 4h blood concentration of alcohol, 1h acetaldehyde concentrations, 2h acetaldehyde concentrations, 4h ALDH units
Statistics, it is as a result as shown in table 1 below：
Influence of the different alcohol-decomposing beverages of table 1 for the drunk rate of mouse, concentration of alcohol, acetaldehyde concentration and acetaldehyde metabolic enzyme
Note:* represent that being compared P ＜ 0.05 with simple alcohol group (represents and do not drink the i.e. simple alcohol group pair of alcohol-decomposing beverage group
Than there were significant differences)；* represents that being compared P ＜ 0.01 with simple alcohol group (represents and do not drink the i.e. simple alcohol of alcohol-decomposing beverage group
Group contrast has pole significant difference).
Result above shows that the alcohol-decomposing beverage of the present invention can be obviously promoted alcohol metabolism, the solution of the oral embodiment of the present invention 1
Wine is to drink again after experiment A groups 0.5h, and experiment A groups are the alcohol levels in blood samples concentration of embodiment 1, acetaldehyde concentration and drunk after 4h
Rate and the contrast of simple alcohol group have reduction, and with statistical significance；Experiment B groups are the alcohol-decomposing beverage of embodiment 3 drunk
Rate, 4h blood concentration of alcohol, 2h acetaldehyde concentrations, which contrast simple alcohol group, also there is conspicuousness to reduce；Experiment C groups are the solution of embodiment 5
Wine contrasts simple alcohol group in 4h blood concentration of alcohol, 2h acetaldehyde concentrations also there is conspicuousness to reduce；Other groups such as patent CN
103181598B groups and the performance of patent CN102218096A groups are all reduced without conspicuousness, it is seen that the solution in the scope of the claims of the present invention
Wine has clear improvement for concentration of alcohol after drinking, acetaldehyde concentration and drunk rate.
Embodiment 7
7.1 experiment material
7.1.1 the people of youth volunteer 12, men and women half and half, 25~35 years old age, weight (70 ± 10) kg, makees complete before experiment
Body is examined, and health condition is good.
7.1.2 experiment wine is 52 ° of bent wines of Luzhou Old Cellar two (commercially available, Luzhou Old Cellar Co., Ltd product)；
It is the sobering-up beverage prepared according to the embodiment of the present invention 1 to test alcohol-decomposing beverage used in A groups；
It is the beverage prepared by CN 103181598B to test alcohol-decomposing beverage used in B groups；
Test alcohol-decomposing beverage used in C groups and press beverage prepared by patent CN102218096A.
7.1.3 detection device alcohol content of exhalation gas detector meets GA307 standards.
7.2 method
7.2.1 process of the test experiment is used with group volunteer itself comparative approach, and blank control group is completed first
Experiment, observation group's experiment is done after 14 days with crowd volunteer, contrasts the otherness of two groups of data.
7.2.2 the people of experiment A group Healthy Youths volunteer 10, men and women half and half, without frequent drinking behavior, average age 30 years old,
Weight (70 ± 10) kg, fasting 6h.Everyone is administered at empty stomach after the alcohol-decomposing beverage 30min of the embodiment of the present invention 1 that to give 52 ° of Luzhous old
Store two bent wine 100mL oral, human exhaled breath's ethanol content test is carried out respectively at 30,60,90,120min.
7.2.3 the people of experiment B group Healthy Youths volunteer 10, men and women half and half, without frequent drinking behavior, average age 30 years old,
Weight (70 ± 10) kg, fasting 6h.Everyone is administered at empty stomach after CN 103181598B alcohol-decomposing beverages 30min that to give 52 ° of Luzhous old
Store two bent wine 100mL oral, human exhaled breath's ethanol content test is carried out respectively at 30,60,90,120min.
7.2.4 the people of experiment C group Healthy Youths volunteer 10, men and women half and half, without frequent drinking behavior, average age 30 years old,
Weight (70 ± 10) kg, fasting 6h.Everyone is administered at empty stomach after CN102218096A alcohol-decomposing beverages 30min that to give 52 ° of Luzhous old
Store two bent wine 100mL oral, human exhaled breath's ethanol content test is carried out respectively at 30,60,90,120min.
7.3 observation index
7.3.1 reference《National Standard of the People's Republic of China GB 19522-2004 vehicle operator's blood, expiration
Alcohol content threshold value is with examining》Requirement formulate the alcohol levels in blood samples concentration standard of this experiment, alcohol levels in blood samples concentration need >=20mg/
100mL.Detect that human exhaled breath's ethanol content is determined.
7.4 result
By the way that to volunteer 0.5h, 1h, 1.5h after drinking, human exhaled breath's ethanol content measure is carried out in 2h different time sections,
As a result it is as shown in table 2 below：
Influence of the different alcohol-decomposing beverages of table 2 for volunteer's alcohol concentration after drinking
Note：* represent to be compared P ＜ 0.05 (representing to be compared with significant difference with experiment B groups) with experiment B groups；⊿ is represented
Compared P ＜ 0.01 with experiment C groups (to represent to be compared with extremely significant difference with experiment C groups
It can be seen that to volunteer 0.5h, 1h, 1.5h after drinking, enter in 2h different time sections from the result of table 2 and Fig. 1
Row human exhaled breath ethanol content is determined, and human volunteer's expiration ethanol content after the alcohol-decomposing beverage of the embodiment of the present invention 1 is taken in discovery
30min in experiment, 60min, 90min and 120min alcohol concentration than the B alcohol-decomposing beverages of CN 103181598 and
CN102218096A alcohol-decomposing beverages are low, and with statistical significance.So as to which the alcohol-decomposing beverage for demonstrating the present invention has acceleration
Ethanol is acted in human body metabolism, and more notable than the like product effect of in the market.
The acute toxicity test of embodiment 8
With reference to《Modern medical experiment skill pandect》(volume two) the 8th chapter 1 " preclinical toxicologic study technology " is set
Acute toxicity testing is counted, as a result shows that the alcohol-decomposing beverage highest dosage of the embodiment of the present invention 1 reaches the normal oral dose of people
100 times or so, that is, the oral 400 bottles of beverages of the people of 70 kg body weights, have not yet to see and toxic side effect produced to animal.It is dynamic
Activity is normal after thing administration, and none dead body weight does not mitigate within 48 hours.Experiment shows that the alcohol-decomposing beverage of the present invention is non-poisonous material
Matter.
Above-described, only presently preferred embodiments of the present invention is not limited to the scope of the present invention, of the invention is upper
Stating embodiment can also make a variety of changes.What i.e. every claims and description according to the present patent application were made
Simply, equivalent changes and modifications, falls within the claims of patent of the present invention.The present invention not detailed description is
Routine techniques content.
Claims (9)
1. a kind of alcohol-decomposing beverage, it is characterised in that be made up of the raw material of following parts by weight：20~40 parts of hoveniae semoveniae semen, the root of kudzu vine 10~
0.5~2 part of 30 parts, 1~5 part of hawthorn, 1~5 part of dried orange peel, 30~60 parts of white granulated sugar, 1~5 part of citric acid and malic acid.
2. alcohol-decomposing beverage according to claim 1, it is characterised in that the consumption of each raw material is：20~30 parts of hoveniae semoveniae semen, Pueraria lobota
20~30 parts of root, 1~5 part of hawthorn, 2~5 parts of dried orange peel, 30~50 parts of white granulated sugar, 1~5 part of citric acid and malic acid 0.5~1
Part.
3. alcohol-decomposing beverage according to claim 2, it is characterised in that the consumption of each raw material is：20 parts of hoveniae semoveniae semen, the root of kudzu vine 30
0.5 part of part, 1 part of hawthorn, 2 parts of dried orange peel, 30 parts of white granulated sugar, 1 part of citric acid and malic acid.
4. alcohol-decomposing beverage according to claim 1, it is characterised in that the consumption of each raw material is：30~40 parts of hoveniae semoveniae semen, Pueraria lobota
1~2 part of 10~20 parts of root, 1~5 part of hawthorn, 1~5 part of dried orange peel, 40~60 parts of white granulated sugar, 2~5 parts of citric acid and malic acid.
5. alcohol-decomposing beverage according to claim 4, it is characterised in that the consumption of each raw material is：40 parts of hoveniae semoveniae semen, the root of kudzu vine 10
2 parts of part, 5 parts of hawthorn, 1 part of dried orange peel, 60 parts of white granulated sugar, 5 parts of citric acid and malic acid.
6. a kind of preparation method of alcohol-decomposing beverage according to any one in Claims 1 to 5, it is characterised in that including
Following steps：
A) hoveniae semoveniae semen, the root of kudzu vine, hawthorn, dried orange peel are weighed by above weight proportion, cleaned, by the clean hoveniae semoveniae semen, kudzu-vine root powder
Broken rear and hawthorn, dried orange peel are mixed to get mixtures of materials；
B) added water into the mixtures of materials, carry out first time extraction, filter to obtain first time extract solution；Add water, carry out the
Second extraction, filters to obtain second of extract solution；
C) the first time extract solution and second of extract solution are merged, filtered, the dense of solid content 30%~40% is made in concentration
Contracting liquid, it is standby；
D) add water and heat into the concentrate, weigh white granulated sugar, citric acid, malic acid respectively, stirring to being completely dissolved, plus
Water constant volume；And
E) feed liquid after constant volume is filtered, sterilizing is filling, and the alcohol-decomposing beverage is made.
7. preparation method according to claim 6, it is characterised in that in the step b), first time amount of water is 10~
20 times, extract 1~2 hour for the first time；Second of amount of water is 5~10 times, second of extraction 0.5~1 hour.
8. preparation method according to claim 7, it is characterised in that the first time extracts and the second temperature extracted is
80~100 DEG C.
9. preparation method according to claim 6, it is characterised in that added water simultaneously into the concentrate in the step d)
It is heated to 55~70 DEG C, adds white granulated sugar, citric acid, malic acid, stirring is to being completely dissolved.
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Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108271963A (en) * | 2018-04-23 | 2018-07-13 | 浙江民生健康科技有限公司 | A kind of herbal beverage and preparation method thereof with antialcoholism action |
| CN108541846A (en) * | 2018-03-03 | 2018-09-18 | 浙江省农业科学院 | A kind of beverage with liver-protecting and alcoholism-relieving function |
| CN108771218A (en) * | 2018-05-24 | 2018-11-09 | 河北华维兰达食品科技有限公司 | A kind of alcohol-decomposing beverage formula |
| CN108967796A (en) * | 2018-07-09 | 2018-12-11 | 宁波赛世健康科技有限公司 | A kind of lemon hoveniae semoveniae semen solid beverage ingredient |
| CN109170398A (en) * | 2018-09-26 | 2019-01-11 | 山东醉小蜜生物科技有限公司 | A kind of alcohol-decomposing beverage and preparation method thereof |
| CN109757573A (en) * | 2019-03-14 | 2019-05-17 | 天水师范学院 | A kind of dark plum hoveniae semoveniae semen fermented tea composite beverage and preparation method thereof |
| CN110583922A (en) * | 2019-10-08 | 2019-12-20 | 深圳三九参智生态科技有限公司 | Beverage for relieving alcoholism and preparation method thereof |
| CN110881657A (en) * | 2019-11-28 | 2020-03-17 | 东莞市东阳光健康食品有限公司 | Composition with function of dispelling effects of alcohol and preparation method and application thereof |
| CN111134262A (en) * | 2019-12-31 | 2020-05-12 | 郑州维谊生物科技有限公司 | Traditional Chinese medicine solid anti-alcohol beverage and preparation method thereof |
| CN111700196A (en) * | 2020-06-29 | 2020-09-25 | 华仁药业股份有限公司 | Traditional Chinese medicine hangover-alleviating functional beverage containing icodextrin |
| CN112120127A (en) * | 2019-06-24 | 2020-12-25 | 艾穆爱斯国际生命株式会社 | Beverage composition containing aged noni stock solution for relieving hangover, and its preparation method |
| CN113105987A (en) * | 2021-05-25 | 2021-07-13 | 成都天河中西医科技保育有限公司 | White spirit capable of reducing accumulation of acetaldehyde in vivo and preparation method thereof |
| CN113318153A (en) * | 2021-06-18 | 2021-08-31 | 苏州尚虞食品科技有限公司 | Composition for preventing drunkenness and/or alcohol addiction and application thereof |
| CN116268239A (en) * | 2023-02-22 | 2023-06-23 | 汉肽生物医药集团有限公司 | A functional beverage containing radix Puerariae and semen Hoveniae, and its preparation method |
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Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108541846A (en) * | 2018-03-03 | 2018-09-18 | 浙江省农业科学院 | A kind of beverage with liver-protecting and alcoholism-relieving function |
| CN108271963A (en) * | 2018-04-23 | 2018-07-13 | 浙江民生健康科技有限公司 | A kind of herbal beverage and preparation method thereof with antialcoholism action |
| CN108271963B (en) * | 2018-04-23 | 2021-06-15 | 浙江民生健康科技有限公司 | A herbal beverage with hangover relieving effect, and its preparation method |
| CN108771218A (en) * | 2018-05-24 | 2018-11-09 | 河北华维兰达食品科技有限公司 | A kind of alcohol-decomposing beverage formula |
| CN108967796A (en) * | 2018-07-09 | 2018-12-11 | 宁波赛世健康科技有限公司 | A kind of lemon hoveniae semoveniae semen solid beverage ingredient |
| CN109170398A (en) * | 2018-09-26 | 2019-01-11 | 山东醉小蜜生物科技有限公司 | A kind of alcohol-decomposing beverage and preparation method thereof |
| CN109757573A (en) * | 2019-03-14 | 2019-05-17 | 天水师范学院 | A kind of dark plum hoveniae semoveniae semen fermented tea composite beverage and preparation method thereof |
| CN112120127A (en) * | 2019-06-24 | 2020-12-25 | 艾穆爱斯国际生命株式会社 | Beverage composition containing aged noni stock solution for relieving hangover, and its preparation method |
| CN110583922A (en) * | 2019-10-08 | 2019-12-20 | 深圳三九参智生态科技有限公司 | Beverage for relieving alcoholism and preparation method thereof |
| CN110881657A (en) * | 2019-11-28 | 2020-03-17 | 东莞市东阳光健康食品有限公司 | Composition with function of dispelling effects of alcohol and preparation method and application thereof |
| CN111134262A (en) * | 2019-12-31 | 2020-05-12 | 郑州维谊生物科技有限公司 | Traditional Chinese medicine solid anti-alcohol beverage and preparation method thereof |
| CN111700196A (en) * | 2020-06-29 | 2020-09-25 | 华仁药业股份有限公司 | Traditional Chinese medicine hangover-alleviating functional beverage containing icodextrin |
| CN113105987A (en) * | 2021-05-25 | 2021-07-13 | 成都天河中西医科技保育有限公司 | White spirit capable of reducing accumulation of acetaldehyde in vivo and preparation method thereof |
| CN113318153A (en) * | 2021-06-18 | 2021-08-31 | 苏州尚虞食品科技有限公司 | Composition for preventing drunkenness and/or alcohol addiction and application thereof |
| CN116268239A (en) * | 2023-02-22 | 2023-06-23 | 汉肽生物医药集团有限公司 | A functional beverage containing radix Puerariae and semen Hoveniae, and its preparation method |
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Application publication date: 20170915 |