CN1424071A - Auxiliary medicine for treating esophagus cancer and processing method thereof - Google Patents

Auxiliary medicine for treating esophagus cancer and processing method thereof Download PDF

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Publication number
CN1424071A
CN1424071A CN02135978A CN02135978A CN1424071A CN 1424071 A CN1424071 A CN 1424071A CN 02135978 A CN02135978 A CN 02135978A CN 02135978 A CN02135978 A CN 02135978A CN 1424071 A CN1424071 A CN 1424071A
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radix
ethanol
twice
salviae miltiorrhizae
fructus psoraleae
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CN1205960C (en
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张兆泉
杜文建
刘立中
刘金凤
刘静
张玉洁
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Jinan No4 People's Hospital
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Jinan No4 People's Hospital
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Abstract

A Chinese medicine for auxiliary therapy to esophagus cancer is prepared from 17 Chinese-medicinal materials including red sage root, astragalus root, pseudostellaria root, oldenlandia, etc. Its advantages are high effect on relaxing the toxic by-effect caused by chemicotherapy, sure curative effect and low cost.

Description

A kind of medicine of the auxiliary treatment esophageal carcinoma and processing method thereof
Affiliated technical field
The present invention is a kind of medicine and processing method thereof of the auxiliary treatment esophageal carcinoma.
Background technology
The esophageal carcinoma is the sticking cured malignant tumor of esophagus that takes place, and is characteristics with the dysphagia, belongs to the category of the traditional Chinese medical science " dysphagic ".Its cause of disease more complicated, still indeterminate at present, it is generally acknowledged that nitrosamine compound, mycete have carcinogenesis, the coarse really up to the mark and long-term physical property such as too fast of taking food of heat food, strong stimulation food and food stimulates can cause epithelium of esophagus damage, inflammation and hypertrophy, brings out canceration.Become with long-term tobacco and wine stimulation, trace element scarcity, inherited genetic factors and place, residence environment in addition certain relation is arranged.Primary disease, is more common in for seeing at most with scale cancer, the stage casing cancer, and adenocarcinoma is taken second place, and is more common in hypomere, and undifferentiated carcinoma is rare.But esophageal carcinoma wall internal diffusion and directly soak into and close on organ, and shift the most common and early, the epimere cancer can reach on the clavicle and cervical lymph node with lymph metastasis, in, hypomere often is transferred to by the esophagus, hilus pulumonis, the other lymph node of cardia.Hematogenous metastasis sees late period, is common in the liver lung and shifts.For middle and advanced stage lose surgical engine can patient with esophageal carcinoma, adopt doctor trained in Western medicine chemicotherapy method short term effect still can, but with advancing also to bring bone marrow depression, hepatic and renal function to reach many toxicities such as radiation esophagitis unusually, and late result is also not satisfactory.
Summary of the invention
The objective of the invention is to: a kind ofly can in chemicotherapy, cooperate the medicine of taking the treatment esophageal carcinoma that heightens the effect of a treatment thereby disclose.
Its raw material of the present invention and weight ratio are: Radix Glehniae 40-50, Radix Salviae Miltiorrhizae 40-50, Radix Astragali 40-60, Radix Pseudostellariae 40-50, Rhizoma Dioscoreae Bulbiferae 10-20, Caulis Spatholobi 45-60, Herba Hedyotidis Diffusae 35-45, Herba Dendrobii 15-25, root of subprostrate sophora 15-25, Flos Inulae 15-25, Haematitum 12-23, Rhizoma Pinelliae Preparata 12-23, Semen Persicae 12-23, Radix Angelicae Sinensis 6-20, Poria 10-30, Fructus Psoraleae 15-30, Nidus Vespae 5-20.
In the present invention, Radix Glehniae, Herba Dendrobii YIN nourishing and the production of body fluid promoting are moisturized; Flos Inulae can cooperate the root of subprostrate sophora sore-throat relieving that reduces phlegm, and can work in coordination with Haematitum, Rhizoma Pinelliae Preparata normalizing the stomach by guiding QI downward again, open diaphragm and end oh; Radix Salviae Miltiorrhizae, Semen Persicae blood circulation promoting and blood stasis dispelling, row stagnation pain; Radix Angelicae Sinensis, Caulis Spatholobi blood circulation promoting and enriching, Rhizoma Dioscoreae Bulbiferae can resolving phlegm and softening hard masses, collaborative again Herba Hedyotidis Diffusae heat-clearing and toxic substances removing, and Nidus Vespae is specially controlled cancerous protuberance, the Radix Astragali, Radix Pseudostellariae, Poria replenishing QI to invigorate the spleen, Fructus Psoraleae invigorating the kidney and strengthening the bones.Above-mentioned each composition synergism, make QI invigorating of the present invention, hemopoietic best results, in the process of the chemicotherapy treatment esophageal carcinoma, be used the present invention and can effectively alleviate the toxicity generation that chemicotherapy causes, human body immunity improving power, and help marrow function to recover, prevent and treat radiation esophagitis, the cancerometastasis of slowing down, be with the tumor life quality thereby improve the patient, improve patient's long term survival rate, it also has, and effect is comprehensive, reliable, the cheap advantage of curative effect.Clinical trial certificate, effective percentage of the present invention are 100%.
The better proportioning of each raw material (weight portion) is among the present invention: Radix Glehniae 42-48, Radix Salviae Miltiorrhizae 42-48, Radix Astragali 45-55, Radix Pseudostellariae 42-48, Rhizoma Dioscoreae Bulbiferae 12-18, Caulis Spatholobi 48-55, Herba Hedyotidis Diffusae 37-42, Herba Dendrobii 16-21, root of subprostrate sophora 16-21, Flos Inulae 16-21, Haematitum 15-23, Rhizoma Pinelliae Preparata 15-23, Semen Persicae 15-23, Radix Angelicae Sinensis 8-18, Poria 20-28, Fructus Psoraleae 18-28, Nidus Vespae 5-12.If will reach better effect, then its proportioning (weight portion) can be: Radix Glehniae 45-48, Radix Salviae Miltiorrhizae 45-48, Radix Astragali 48-52, Radix Pseudostellariae 45-48, Rhizoma Dioscoreae Bulbiferae 13-17, Caulis Spatholobi 50-55, Herba Hedyotidis Diffusae 40-42, Herba Dendrobii 18-20, root of subprostrate sophora 18-20, Flos Inulae 18-21, Haematitum 18-20, Rhizoma Pinelliae Preparata 19-22, Semen Persicae 19-22, Radix Angelicae Sinensis 10-15, Poria 20-25, Fructus Psoraleae 20-25, Nidus Vespae 8-10.
The present invention is an endo-medicine, it can be made into peroral dosage forms such as decoction, pill, powder, if be made as decoction, its processing method comprises the steps: that (1) all put into the ethanol heating and refluxing extraction twice with Radix Salviae Miltiorrhizae, Rhizoma Pinelliae Preparata, Fructus Psoraleae, Rhizoma Dioscoreae Bulbiferae, each 0.5-1.5 hour, merge extracted twice liquid; (2) medicinal residues behind the ethanol extraction and other composition are decocted with water twice, each 1-2 hour, merge decocting liquid twice, put cold; (3) merge extracting solution of (1) gained and the decocting liquid of (2) gained; (4) medicinal liquid natural juice is added ethanol and make ethanol content reach 50-75%, put heavy 15-36 hour, after the filtration decompression filtrate recycling ethanol made medicinal liquid natural juice.The extracting solution that be preferably in filtration at the above-mentioned decocting liquid that obtains in by step (2), concentrates back and step (1) gained merges.
The specific embodiment
Embodiment one:
The raw material composition and the weight portion thereof of present embodiment are respectively: Radix Glehniae 40, Radix Salviae Miltiorrhizae 46, the Radix Astragali 42, Radix Pseudostellariae 41, Rhizoma Dioscoreae Bulbiferae 15, Caulis Spatholobi 44, Herba Hedyotidis Diffusae 36, Herba Dendrobii 16, root of subprostrate sophora 18, Flos Inulae 7, Haematitum 16, Rhizoma Pinelliae Preparata 15, Semen Persicae 14, Radix Angelicae Sinensis 12, Poria 18, Fructus Psoraleae 24, Nidus Vespae 16.Present embodiment is adding man-hour, at first Radix Salviae Miltiorrhizae, Rhizoma Pinelliae Preparata, Fructus Psoraleae, Rhizoma Dioscoreae Bulbiferae is put into ethanol heating and refluxing extraction twice by its weight portion number average, each 0.5 hour, merges extracted twice liquid; And the medicinal residues behind the ethanol extraction and other composition are decocted with water twice, and each 1.5 hours, merge decocting liquid twice, filter, put cold; Obtain medicinal liquid natural juice behind the decocting liquid that the extracting solution of merging gained reaches; Medicinal liquid natural juice is added ethanol make ethanol content reach 60%, put heavy 18 hours, after the filtration decompression filtrate recycling ethanol made medicinal liquid natural juice.
Embodiment two:
The raw material composition and the weight portion thereof of present embodiment are respectively: Radix Glehniae 41, Radix Salviae Miltiorrhizae 49, the Radix Astragali 46 Radix Pseudostellariaes 44, Rhizoma Dioscoreae Bulbiferae 10, Caulis Spatholobi 60, Herba Hedyotidis Diffusae 41, Herba Dendrobii 18, root of subprostrate sophora 20, Flos Inulae 22, Haematitum 19, Rhizoma Pinelliae Preparata 13, Semen Persicae 17, Radix Angelicae Sinensis 8, Poria 24, Fructus Psoraleae 17, Nidus Vespae 10.Present embodiment is adding man-hour, at first Radix Salviae Miltiorrhizae, Rhizoma Pinelliae Preparata, Fructus Psoraleae, Rhizoma Dioscoreae Bulbiferae is put into ethanol heating and refluxing extraction twice by its weight portion number average, each 40 minutes, merges extracted twice liquid; And the medicinal residues behind the ethanol extraction and other composition are decocted with water twice, and each 1 hour, merge decocting liquid twice, filter, put cold; Obtain medicinal liquid natural juice behind the decocting liquid that the extracting solution of merging gained reaches; Medicinal liquid natural juice is added ethanol make ethanol content reach 55%, put heavy 15 hours, after the filtration decompression filtrate recycling ethanol made medicinal liquid natural juice.
Embodiment three:
The raw material composition and the weight portion thereof of present embodiment are respectively: Radix Glehniae 42, Radix Salviae Miltiorrhizae 42, the Radix Astragali 40, Radix Pseudostellariae 42, Rhizoma Dioscoreae Bulbiferae 18, Caulis Spatholobi 52, Herba Hedyotidis Diffusae 38, Herba Dendrobii 25, root of subprostrate sophora 16, Flos Inulae 18, Haematitum 12, Rhizoma Pinelliae Preparata 17, Semen Persicae 20, Radix Angelicae Sinensis 11, Poria 20, Fructus Psoraleae 25, Nidus Vespae 6.Present embodiment is adding man-hour, at first Radix Salviae Miltiorrhizae, Rhizoma Pinelliae Preparata, Fructus Psoraleae, Rhizoma Dioscoreae Bulbiferae is put into ethanol heating and refluxing extraction twice by its weight portion number average, each 50 minutes, merges extracted twice liquid; And the medicinal residues behind the ethanol extraction and other composition are decocted with water twice, and each 75 minutes, merge decocting liquid twice, filter, put cold; Obtain medicinal liquid natural juice behind the decocting liquid that the extracting solution of merging gained reaches; Medicinal liquid natural juice is added ethanol make ethanol content reach 65%, put heavy 20 hours, after the filtration decompression filtrate recycling ethanol made medicinal liquid natural juice.
Embodiment four:
The raw material composition and the weight portion thereof of present embodiment are respectively: Radix Glehniae 43, Radix Salviae Miltiorrhizae 47, the Radix Astragali 58, Radix Pseudostellariae 48, Rhizoma Dioscoreae Bulbiferae 14, Caulis Spatholobi 46, Herba Hedyotidis Diffusae 43, Herba Dendrobii 23, root of subprostrate sophora 23, Flos Inulae 16, Haematitum 17, Rhizoma Pinelliae Preparata 22, Semen Persicae 15, Radix Angelicae Sinensis 9, Poria 26, Fructus Psoraleae 15, Nidus Vespae 5.Present embodiment is adding man-hour, at first Radix Salviae Miltiorrhizae, Rhizoma Pinelliae Preparata, Fructus Psoraleae, Rhizoma Dioscoreae Bulbiferae is put into ethanol heating and refluxing extraction twice by its weight portion number average, each 1 hour, merges extracted twice liquid; And the medicinal residues behind the ethanol extraction and other composition are decocted with water twice, and each 100 minutes, merge decocting liquid twice, filter, put cold; Obtain medicinal liquid natural juice behind the decocting liquid that the extracting solution of merging gained reaches; Medicinal liquid natural juice is added ethanol make ethanol content reach 70%, put heavy 22 hours, after the filtration decompression filtrate recycling ethanol made medicinal liquid natural juice.
Embodiment five:
The raw material composition and the weight portion thereof of present embodiment are respectively: Radix Glehniae 44, Radix Salviae Miltiorrhizae 43, the Radix Astragali 52, Radix Pseudostellariae 46, Rhizoma Dioscoreae Bulbiferae 11, Caulis Spatholobi 58, Herba Hedyotidis Diffusae 35, Herba Dendrobii 17, root of subprostrate sophora 21, Flos Inulae 24, Haematitum 14, Rhizoma Pinelliae Preparata 16, Semen Persicae 19, Radix Angelicae Sinensis 14, Poria 12, Fructus Psoraleae 20, Nidus Vespae 20.Present embodiment is adding man-hour, at first Radix Salviae Miltiorrhizae, Rhizoma Pinelliae Preparata, Fructus Psoraleae, Rhizoma Dioscoreae Bulbiferae is all put into ethanol heating and refluxing extraction twice, each 70 minutes, merges extracted twice liquid; Medicinal residues behind the ethanol extraction and other composition are decocted with water twice, each 2 hours, merge decocting liquid twice, put cold; Merge extractive liquid, and decocting liquid then; Again medicinal liquid natural juice is added ethanol and make ethanol content reach 75%, put heavy 24 hours, after the filtration decompression filtrate recycling ethanol made medicinal liquid natural juice.
Embodiment six:
The raw material composition and the weight portion thereof of present embodiment are respectively: Radix Glehniae 45, Radix Salviae Miltiorrhizae 50, the Radix Astragali 44, Radix Pseudostellariae 40, Rhizoma Dioscoreae Bulbiferae 17, Caulis Spatholobi 40, Herba Hedyotidis Diffusae 42, Herba Dendrobii 22, root of subprostrate sophora 19, Flos Inulae 20, Haematitum 20, Rhizoma Pinelliae Preparata 23, Semen Persicae 18, Radix Angelicae Sinensis 10, Poria 25, Fructus Psoraleae 28, Nidus Vespae 18.Present embodiment is adding man-hour, at first Radix Salviae Miltiorrhizae, Rhizoma Pinelliae Preparata, Fructus Psoraleae, Rhizoma Dioscoreae Bulbiferae is all put into ethanol heating and refluxing extraction twice, each 1.5 hours, merges extracted twice liquid; Medicinal residues behind the ethanol extraction and other composition are decocted with water twice, each 1 hour, merge decocting liquid twice, put cold; Merge extractive liquid, and decocting liquid then; Again medicinal liquid natural juice is added ethanol and make ethanol content reach 50%, put heavy 15 hours, after the filtration decompression filtrate recycling ethanol made medicinal liquid natural juice.
Embodiment seven:
The raw material composition and the weight portion thereof of present embodiment are respectively: Radix Glehniae 46, Radix Salviae Miltiorrhizae 44, the Radix Astragali 50, Radix Pseudostellariae 50, Rhizoma Dioscoreae Bulbiferae 19, Caulis Spatholobi 55, Herba Hedyotidis Diffusae 38, Herba Dendrobii 19, root of subprostrate sophora 24, Flos Inulae 15, Haematitum 23, Rhizoma Pinelliae Preparata 12, Semen Persicae 16, Radix Angelicae Sinensis 13, Poria 15, Fructus Psoraleae 19, Nidus Vespae 8.Present embodiment is adding man-hour, at first Radix Salviae Miltiorrhizae, Rhizoma Pinelliae Preparata, Fructus Psoraleae, Rhizoma Dioscoreae Bulbiferae is all put into ethanol heating and refluxing extraction twice, each 90 minutes, merges extracted twice liquid; Medicinal residues behind the ethanol extraction and other composition are decocted with water twice, each 1 hour, merge decocting liquid twice, put cold; Merge extractive liquid, and decocting liquid then; Again medicinal liquid natural juice is added ethanol and make ethanol content reach 55%, put heavy 30 hours, after the filtration decompression filtrate recycling ethanol made medicinal liquid natural juice.
Embodiment eight:
The raw material composition and the weight portion thereof of present embodiment are respectively: Radix Glehniae 45, Radix Salviae Miltiorrhizae 45, the Radix Astragali 50, Radix Pseudostellariae 45, Rhizoma Dioscoreae Bulbiferae 15, Caulis Spatholobi 50, Herba Hedyotidis Diffusae 40, Herba Dendrobii 20, root of subprostrate sophora 20, Flos Inulae 20, Haematitum 16, Rhizoma Pinelliae Preparata 16, Semen Persicae 16, Radix Angelicae Sinensis 10, Poria 20, Fructus Psoraleae 20, Nidus Vespae 10.Present embodiment is adding man-hour, at first Radix Salviae Miltiorrhizae, Rhizoma Pinelliae Preparata, Fructus Psoraleae, Rhizoma Dioscoreae Bulbiferae is all put into ethanol heating and refluxing extraction twice, each 1 hour, merges extracted twice liquid; Medicinal residues behind the ethanol extraction and other composition are decocted with water twice, each 1-2 hour, merge decocting liquid twice, concentrate, put cold after the filtration; Merge extractive liquid, and decocting liquid afterwards; Again medicinal liquid natural juice is added ethanol and make ethanol content reach 65%, put heavy 24 hours, after the filtration decompression filtrate recycling ethanol made medicinal liquid natural juice.Stir evenly after medicinal liquid natural juice added water, static 24 hours after-filtration concentrate this filtrate again, add an amount of antiseptic, correctives is made finished product.
Embodiment nine:
Radix Glehniae 47, Radix Salviae Miltiorrhizae 48, the Radix Astragali 55, Radix Pseudostellariae 47, Rhizoma Dioscoreae Bulbiferae 12, Caulis Spatholobi 48, Herba Hedyotidis Diffusae 44, Herba Dendrobii 15, root of subprostrate sophora 22, Flos Inulae 23, Haematitum 15, Rhizoma Pinelliae Preparata 18, Semen Persicae 22, Radix Angelicae Sinensis 20, Poria 30, Fructus Psoraleae 30, Nidus Vespae 7.Present embodiment is adding man-hour, at first Radix Salviae Miltiorrhizae, Rhizoma Pinelliae Preparata, Fructus Psoraleae, Rhizoma Dioscoreae Bulbiferae is all put into ethanol heating and refluxing extraction twice, each 2 hours, merges extracted twice liquid; Medicinal residues behind the ethanol extraction and other composition are decocted with water twice, each 1 hour, merge decocting liquid twice, concentrate, put cold after the filtration; Merge extractive liquid, and decocting liquid afterwards; Again medicinal liquid natural juice is added ethanol and make ethanol content reach 70%, put heavy 32 hours, after the filtration decompression filtrate recycling ethanol made medicinal liquid natural juice.Stir evenly after medicinal liquid natural juice added water, static 15 hours after-filtration concentrate this filtrate again, add an amount of antiseptic, correctives is made finished product.
Embodiment ten:
Radix Glehniae 48, Radix Salviae Miltiorrhizae 45, the Radix Astragali 60, Radix Pseudostellariae 43, Rhizoma Dioscoreae Bulbiferae 16, Caulis Spatholobi 42, Herba Hedyotidis Diffusae 40, Herba Dendrobii 24, root of subprostrate sophora 15, Flos Inulae 19, Haematitum 18, Rhizoma Pinelliae Preparata 19, Semen Persicae 12, Radix Angelicae Sinensis 6, Poria 28, Fructus Psoraleae 22, Nidus Vespae 12.Present embodiment is adding man-hour, at first Radix Salviae Miltiorrhizae, Rhizoma Pinelliae Preparata, Fructus Psoraleae, Rhizoma Dioscoreae Bulbiferae is all put into ethanol heating and refluxing extraction twice, each 1.5 hours, merges extracted twice liquid; Medicinal residues behind the ethanol extraction and other composition are decocted with water twice, each 1.5 hours, merge decocting liquid twice, concentrate, put cold after the filtration; Merge extractive liquid, and decocting liquid afterwards; Again medicinal liquid natural juice is added ethanol and make ethanol content reach 75%, put heavy 36 hours, after the filtration decompression filtrate recycling ethanol made medicinal liquid natural juice.Stir evenly after medicinal liquid natural juice added water, static 10 hours after-filtration concentrate this filtrate again, add an amount of antiseptic, correctives is made finished product.
Embodiment 11:
Radix Glehniae 49, Radix Salviae Miltiorrhizae 41, the Radix Astragali 56, Radix Pseudostellariae 49, Rhizoma Dioscoreae Bulbiferae 20, Caulis Spatholobi 56, Herba Hedyotidis Diffusae 45, Herba Dendrobii 20, root of subprostrate sophora 25, Flos Inulae 21, Haematitum 13, Rhizoma Pinelliae Preparata 14, Semen Persicae 23, Radix Angelicae Sinensis 16, Poria 22, Fructus Psoraleae 23, Nidus Vespae 9.Present embodiment is adding man-hour, at first Radix Salviae Miltiorrhizae, Rhizoma Pinelliae Preparata, Fructus Psoraleae, Rhizoma Dioscoreae Bulbiferae is all put into ethanol heating and refluxing extraction twice, each 1 hour, merges extracted twice liquid; Medicinal residues behind the ethanol extraction and other composition are decocted with water twice, each 2 hours, merge decocting liquid twice, concentrate, put cold after the filtration; Merge extractive liquid, and decocting liquid afterwards; Again medicinal liquid natural juice is added ethanol and make ethanol content reach 65%, put heavy 20 hours, after the filtration decompression filtrate recycling ethanol made medicinal liquid natural juice.Stir evenly after medicinal liquid natural juice added water, static 24 hours after-filtration concentrate this filtrate again, add an amount of antiseptic, correctives is made finished product.
Embodiment 12:
Radix Glehniae 50, Radix Salviae Miltiorrhizae 40, the Radix Astragali 48, Radix Pseudostellariae 45, Rhizoma Dioscoreae Bulbiferae 13, Caulis Spatholobi 50, Herba Hedyotidis Diffusae 39, Herba Dendrobii 21, root of subprostrate sophora 20, Flos Inulae 20, Haematitum 16, Rhizoma Pinelliae Preparata 16, Semen Persicae 16, Radix Angelicae Sinensis 10, Poria 20, Fructus Psoraleae 20, Nidus Vespae 10.Present embodiment is adding man-hour, at first Radix Salviae Miltiorrhizae, Rhizoma Pinelliae Preparata, Fructus Psoraleae, Rhizoma Dioscoreae Bulbiferae is all put into ethanol heating and refluxing extraction twice, each 1.5 hours, merges extracted twice liquid; Medicinal residues behind the ethanol extraction and other composition are decocted with water twice, each 1 hour, merge decocting liquid twice, concentrate, put cold after the filtration; Merge extractive liquid, and decocting liquid afterwards; Again medicinal liquid natural juice is added ethanol and make ethanol content reach 55%, put heavy 24 hours, after the filtration decompression filtrate recycling ethanol made medicinal liquid natural juice.Stir evenly after medicinal liquid natural juice added water, static 30 hours after-filtration concentrate this filtrate again, add an amount of antiseptic, correctives is made finished product.

Claims (5)

1, a kind of medicine of the auxiliary treatment esophageal carcinoma is characterized in that: its raw material and weight portion are: Radix Glehniae 40-50, Radix Salviae Miltiorrhizae 40-50, Radix Astragali 40-60, Radix Pseudostellariae 40-50, Rhizoma Dioscoreae Bulbiferae 10-20, Caulis Spatholobi 45-60, Herba Hedyotidis Diffusae 35-45, Herba Dendrobii 15-25, root of subprostrate sophora 15-25, Flos Inulae 15-25, Haematitum 12-23, Rhizoma Pinelliae Preparata 12-23, Semen Persicae 12-23, Radix Angelicae Sinensis 6-20, Poria 10-30, Fructus Psoraleae 15-30, Nidus Vespae 5-20.
2, the medicine of the auxiliary treatment esophageal carcinoma according to claim 1 is characterized in that: its raw material and weight portion are: Radix Glehniae 42-48, Radix Salviae Miltiorrhizae 42-48, Radix Astragali 45-55, Radix Pseudostellariae 42-48, Rhizoma Dioscoreae Bulbiferae 12-18, Caulis Spatholobi 48-55, Herba Hedyotidis Diffusae 37-42, Herba Dendrobii 16-21, root of subprostrate sophora 16-21, Flos Inulae 16-21, Haematitum 15-23, Rhizoma Pinelliae Preparata 15-23, Semen Persicae 15-23, Radix Angelicae Sinensis 8-18, Poria 20-28, Fructus Psoraleae 18-28, Nidus Vespae 5-12.
3, the medicine of the auxiliary treatment esophageal carcinoma according to claim 2 is characterized in that: its raw material and weight portion are: Radix Glehniae 45-48, Radix Salviae Miltiorrhizae 45-48, Radix Astragali 48-52, Radix Pseudostellariae 45-48, Rhizoma Dioscoreae Bulbiferae 13-17, Caulis Spatholobi 50-55, Herba Hedyotidis Diffusae 40-42, Herba Dendrobii 18-20, root of subprostrate sophora 18-20, Flos Inulae 18-21, Haematitum 18-20, Rhizoma Pinelliae Preparata 19-22, Semen Persicae 19-22, Radix Angelicae Sinensis 10-15, Poria 20-25, Fructus Psoraleae 20-25, Nidus Vespae 8-10.
4, according to the medicine processing method of the claim 1 or the 2 or 3 described auxiliary treatment esophageal carcinoma, it is characterized in that: it comprises the steps: that (1) all put into the ethanol heating and refluxing extraction twice with Radix Salviae Miltiorrhizae, Rhizoma Pinelliae Preparata, Fructus Psoraleae, Rhizoma Dioscoreae Bulbiferae, each 0.5-2 hour, merge extracted twice liquid; (2) medicinal residues behind the ethanol extraction and other composition are decocted with water twice, each 1-2 hour, merge decocting liquid twice, put cold; (3) merge extracting solution of (1) gained and the decocting liquid of (2) gained; (4) medicinal liquid natural juice is added ethanol and make ethanol content reach 50-75%, put heavy 15-36 hour, after the filtration decompression filtrate recycling ethanol made medicinal liquid natural juice.
5, the medicine processing method of the auxiliary treatment esophageal carcinoma according to claim 4 is characterized in that: the decocting liquid that is obtained by step (2) is filtering, is concentrating the extracting solution merging of back with step (1) gained.
CNB021359784A 2002-12-13 2002-12-13 Auxiliary medicine for treating esophagus cancer and processing method thereof Expired - Fee Related CN1205960C (en)

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CN100381164C (en) * 2003-12-31 2008-04-16 赵恒� Medicine for treating radiation diseases
CN100411668C (en) * 2005-05-20 2008-08-20 米兴华 A cancer-treating medicine
CN103656319A (en) * 2013-12-15 2014-03-26 高继绪 Application for treating acute radiation-induced esophagitis
CN104435930A (en) * 2014-11-28 2015-03-25 于朝霞 Chinese traditional medicine for healing of tumor patients after radiotherapy and chemotherapy
CN105853604A (en) * 2016-05-11 2016-08-17 张士舜 Traditional Chinese medicinal composition for treating esophagus cancer and preparation method of traditional Chinese medicinal composition

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100381164C (en) * 2003-12-31 2008-04-16 赵恒� Medicine for treating radiation diseases
CN100411668C (en) * 2005-05-20 2008-08-20 米兴华 A cancer-treating medicine
CN103656319A (en) * 2013-12-15 2014-03-26 高继绪 Application for treating acute radiation-induced esophagitis
CN103656319B (en) * 2013-12-15 2016-02-17 高继绪 A kind of external traditional Chinese medicinal application for the treatment of acute radiation-induced esophagitis
CN104435930A (en) * 2014-11-28 2015-03-25 于朝霞 Chinese traditional medicine for healing of tumor patients after radiotherapy and chemotherapy
CN105853604A (en) * 2016-05-11 2016-08-17 张士舜 Traditional Chinese medicinal composition for treating esophagus cancer and preparation method of traditional Chinese medicinal composition

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