CN1061846C

CN1061846C - Traditional Chinese medicine prescription for tonifying the kidney reinforcing the spleen and nourishing the blood and preparation process

Info

Publication number: CN1061846C
Application number: CN97107619A
Authority: CN
Inventors: 黄碧有
Original assignee: Individual
Current assignee: Individual
Priority date: 1997-07-30
Filing date: 1997-07-30
Publication date: 2001-02-14
Anticipated expiration: 2017-07-30
Also published as: CN1206601A

Abstract

The present invention relates to a prescription which comprises ass-hide glue, deerhorn glue, turtle glue, ginseng, red sage root, epimedium herb, malaytea scurfpea fruit, fruit of Chinese magnoliavine, white atractylodes rhizome, licorice, astragalus root, Chinese angelica, tuckahoe and aucklandia root. A preparation method comprises: the ginseng, the red sage root, the fruit of Chinese magnoliavine, the tuckahoe, the epimedium herb and the malaytea scurfpea fruit are prepared into a percolate, and the white atractylodes rhizome and the aucklandia root are prepared into volatile oil; the prepared percolate, the volatile oil, a water decoction and jelly are mixed, filtrated and concentrated, the pH value of the mixture is regulated, and the mixture is sterilized and packaged. The present invention has the advantage that the prescription can tonify the kidney, invigorate the spleen, enrich blood, enhance immunological function, and relieve the toxic and side effect of radiotherapy and chemotherapy on the stomach intestine and blood formation.

Description

A kind of Chinese medicine of kidney and spleen invigorating hemopoietic and preparation method

The invention belongs to the medicinal preparation technical field that derives from vegetable material.

Theory of Chinese medical science thinks that the basic reason that disease produces is weakened body resistance.So suffer from a deficiency of the kidney is the physiological foundation that carcinoma produces.Ming Dynasty's physician's Zhang Jingyue is said: " people of taste deficiency and debilitating disorder has the disease of accumulation more." " Required Readings for Medical Professionals. an accumulation piece of writing " point out: " long-pending one-tenth also, QI-insufficiency just, pathogen occupies it." illustrating that tumorigenic endogenous cause of ill is that the positive deficiency of vital energy is promptly suffered from a deficiency of the kidney, exopathogenic factor then is that pathogen is the influence of various carcinogenic factors, various carcinogenic factors work by suffering from a deficiency of the kidney, and cause the generation of carcinoma.The western medical treatment carcinoma adopts radiation treatment and chemotherapy, and regular meeting produces some toxic and side effects, causes the imbalance of Pi renal function, leukopenia, and whole blood descends, the general immunity function reduction.And adopt kidney and spleen invigorating hemopoietic Chinese medicine, and can the kidney tonifying spleen invigorating, strengthen the hemopoietic function, fundamentally strengthen healthy energy, suppress the generation of carcinoma, and can alleviate the caused leukopenia of radiotherapy chemotherapy, whole blood descends, the toxic and side effects of general immunity function reduction.

The object of the present invention is to provide a kind of is the prescription and the preparation method of the Chinese medicine with the kidney invigorating, spleen invigorating, hemopoietic function of monarch drug with Colla cornus cervi, Colla Plastri Testudinis, Colla Corii Asini, Radix Ginseng, Radix Salviae Miltiorrhizae, Herba Epimedii, Fructus Psoraleae, Fructus Schisandrae Chinensis eight medicines.

The object of the present invention is achieved like this: a kind of kidney and spleen invigorating hemopoietic Chinese medicine, its composition comprises Colla Corii Asini 1, Colla cornus cervi 2, Colla Plastri Testudinis 3, Radix Ginseng 4, Radix Salviae Miltiorrhizae 5, structure Fructus Lycii 6, Herba Epimedii 7, Fructus Psoraleae 8, Fructus Schisandrae Chinensis 9, the Rhizoma Atractylodis Macrocephalae 10, Radix Glycyrrhizae Preparata 11, the Radix Astragali 12, Radix Angelicae Sinensis 13, Poria 14, Caulis Spatholobi 15, the Radix Aucklandiae 16, water 17.

Wherein:

The effect of Colla Corii Asini 1 is tonifying blood and arresting bleeding, grow positive lung moistening;

The effect of Colla cornus cervi 2 is that temperature compensating below element, nourishing YIN the yang aspect of yang, dredging DU Meridian arteries and veins, promoting generation of vital essence and blood, hemostasis collapse;

The effect of Colla Plastri Testudinis 3 is kind logical conception vessels, grow positive YANG hyperactivity suppressing, kidney tonifying is good for the stomach;

The effect of Radix Ginseng 4 is strongly invigorating primordial QI, benefit Pi lung benefiting, promoting the production of body fluid to quench thirst, calming the nerves increases intelligence;

The effect of Radix Salviae Miltiorrhizae 5 is that blood stasis dispelling, removing heat from blood fully alive disappear bitterly, nourishing blood to tranquillize the mind;

The effect of Fructus Lycii 6 is nourishing the liver and kidney, make eye bright, lung moistening;

The effect of Herba Epimedii 7 is kidney invigorating and YANG supporting, expelling wind and removing dampness;

The effect of Fructus Psoraleae 8 is kidney invigorating and YANG supporting, controlling nocturnal emission with astringent drugs reducing urination, warming spleen and stopping diarrha;

The effect of Fructus Schisandrae Chinensis 9 is astringe the lung nourishing kidney, the arresting sweating that promotes the production of body fluid, arresting seminal emission antidiarrheal, mind tranquilizing and the heart calming;

Rhizoma Atractylodis macrocephalae 10 effect is that air making-up and spleen enlivening, dampness diuretic, hidroschesis are antiabortive;

The effect of Radix Glycyrrhizae Preparata 11 is invigorating the spleen and replenishing QI, nourishing the lung to arrest cough, relieving spasm to stop pain, the mitigation property of medicine;

The effect of the Radix Astragali 12 is that tonifying Qi and lifting yang, benefit are defended consolidating superficial resistance, promoting pus discharge and tissue regeneration strengthening, diuretic detumescent;

The effect of Radix Angelicae Sinensis 13 be enrich blood, invigorate blood circulation, pain relieving, intestine moistening;

The effect of Poria 14 is promoting diuresis to eliminate damp pathogen, spleen invigorating, calms the nerves;

The effect of Caulis Spatholobi 15 is that promoting the circulation of blood is enriched blood, relaxing muscles and tendons and activating QI and blood in the collateral;

The effect of the Radix Aucklandiae 16 is circulation of qi promoting, transfer in, pain relieving;

Water 17 is as solvent.

Colla cornus cervi is the product of pure sun, kind dredging DU Meridian arteries and veins, high complement sun; Colla Plastri Testudinis is the product of pure the moon, and kind logical conception vessel is grown positive kidney tonifying; The Colla Corii Asini replenishing essence helps the moon; Three glue match, and tonifying both YIN and YANG both can be grown the water replenishing essence, again can beneficial fiery tonifying YANG, have the strong effect of powerful nourishing.Radix Ginseng, strongly invigorating primordial QI; Radix Salviae Miltiorrhizae can nourish blood and enrich blood, but blood circulation and promoting silt again; Two medicines phase 5, nourishing kidney-yin, invigorating primordial QI, blood stasis removing blood, then the merit of blood-enriching and blood-promoting circulation is stronger.Herba Epimedii is mended the gate of vitality, beneficial vital essence,, kidney muscles and bones, diuresis; Fructus Psoraleae is controlled diarrhea due to kidney-dificiency, the logical gate of vitality, warm public region; Fructus Schisandrae Chinensis, controlling nocturnal emission with astringent drugs, arresting sweating, three medicines are harmonious, and kidney invigorating and YANG supporting is arranged, Gu wooden arresting seminal emission is moving.More than eight medicines blendings, the tool the kidney invigorating is filled out the marrow spermatogenesis and is enriched blood altogether, is to be monarch drug.

Dysfunction of spleen and stomach, then biochemical passive, use the Rhizoma Atractylodis Macrocephalae, Poria, Radix Glycyrrhizae Preparata, Radix Ginseng decoction of four noble drugs, can spleen invigorating, QI invigorating, stomach function regulating, the spleen and stomach regulating function strengthens the absorbability of small intestinal, makes biochemical actively, is to be ministerial drug.

Be aided with the Radix Astragali again, strengthen qi-supplementing, blood-engendering, the merit of blood circulation promoting competent silt, the Radix Aucklandiae is drying damp and strengthening spleen, and warming middle-JIAO helps fortune, promoting the circulation of QI to relieve pain.

The formulation weight ratio of each medicine is as follows:

Colla Corii Asini 5-30 gram; Colla cornus cervi 5-30 gram; Colla Plastri Testudinis 5-30 gram;

Radix Ginseng 5-30 gram; Radix Salviae Miltiorrhizae 10-50 gram; Fructus Lycii 10-50 gram; Herba Epimedii 10-100 gram;

Fructus Psoraleae 10-30 gram; Fructus Schisandrae Chinensis 10-50 gram; Rhizoma Atractylodis Macrocephalae 5-30 gram;

Radix Glycyrrhizae Preparata 5-30 gram; Radix Astragali 10-100 gram; Radix Angelicae Sinensis 5-30 gram;

Poria 5-40 gram; Caulis Spatholobi 30-100 gram; Radix Aucklandiae 5-30 gram; Water.

The present invention can also can make oral liquid and tablets directly to be decocted in water for oral dose.The preparation technology of oral liquid is as follows:

A, preparation percolate: Radix Ginseng 4, Radix Salviae Miltiorrhizae 5, Herba Epimedii 7, Fructus Psoraleae 8, Fructus Schisandrae Chinensis 9, Poria 14 Six-element medicines are made coarse grain (80 order), adding concentration 60% ethanol soaked 72 hours at normal temperatures, prepare percolate with percolation, reclaim ethanol, be concentrated into the relative density ratio of institute's pastille density (water density with) 1: 1.18 (50 ℃ time) then.

B, preparation volatile oil:, prepare volatile oil with the way of distillation, extraction time 5-6 hour with the Rhizoma Atractylodis Macrocephalae 10, Radix Angelicae Sinensis 13, the Radix Aucklandiae 16 3 flavor medicines.

C, preparation decocting liquid: Fructus Lycii 6, Radix Glycyrrhizae Preparata 11, the Radix Astragali 12, Caulis Spatholobi 15 four Chinese medicines are added decocting become decocting liquid, add decocting again after pouring out decocting liquid, fry in shallow oil each 40 minutes altogether three times.When decocting for the third time, add the medicinal residues behind the percolation among the technology a, and the medicinal residues that technology b extracts behind the volatile oil are fried in shallow oil altogether.Three decocting liquids are merged, and concentrated relative density is 1: the decocting liquid of (50 ℃ time).Add 2 times of concentration by volume 95% ethanol, left standstill 24 hours, filter and remove residue reclaims ethanol.

D, three glue moltens: with Colla Corii Asini 1, Colla cornus cervi 2, Colla Plastri Testudinis 3 three flavor connective water heating, making its molten is jelly.

E, preparation mixed liquor: the percolate that will prepare with technology a, the molten jelly of the decocting liquid of the volatile oil of technology b preparation, technology c preparation, technology d preparation mixes at normal temperatures, filter, the simmer down to relative density is the mixed liquor of 1: 1.8 (50 ℃ time), regulates pH value and makes it reach PH4.5.Carry out packing, sterilization then.

Advantage of the present invention is, is core with the kidney tonifying, essence replenishing hemopoietic, and realizing rectifies sets upright gas, promote blood to give birth to, improve the neuroendocrine immunologic function, have the multipath regulating action of too many levels, by the kidney invigorating human body immunity improving function, strengthen metabolism, promote hemopoietic function, thereby make body reach " healthy energy internal memory; heresy can not be done ", can postpone or reduce the generation of carcinoma, remove the residual cancer cell, alleviate radiotherapy, chemotherapy toxic and side effects gastrointestinal function and hemopoietic system.

The present invention treats 100 routine carcinoma patients, and better curative effect is all arranged.Can alleviate the toxicity of chemotherapy, radiotherapy, leukocyte increasing is (2 weeks of taking medicine can obviously rise) rapidly.Maintain normal range, radiotherapy, chemotherapy are carried out smoothly, improve immunologic function, remove the effect of residual cancer cell.This prescription can with other immunization therapy synergism, do not find any side effect.

Be that three prescriptions of the present invention are realized example below:

Embodiment one:

Colla Corii Asini 12 grams, Colla cornus cervi 20 grams; Colla Plastri Testudinis 30 grams; Radix Ginseng 15 grams;

Radix Salviae Miltiorrhizae 10 grams, Fructus Lycii 30 grams; Herba Epimedii 20 grams; Fructus Psoraleae 25 grams; Fructus Schisandrae Chinensis 15 grams;

The Rhizoma Atractylodis Macrocephalae 10 grams; Radix Glycyrrhizae Preparata 15 grams; The Radix Astragali 100 grams; Radix Angelicae Sinensis 10 grams;

Poria 20 grams; Caulis Spatholobi 30 grams; The Radix Aucklandiae 25 grams.

Embodiment two:

Colla Corii Asini 6 grams; Colla cornus cervi 15 grams; Colla Plastri Testudinis 5 grams; Radix Ginseng 30 grams;

Radix Salviae Miltiorrhizae 30 grams; Fructus Lycii 20 grams; Herba Epimedii 50 grams; Fructus Psoraleae 5 grams; Fructus Schisandrae Chinensis 20 grams;

The Rhizoma Atractylodis Macrocephalae 30 grams; Radix Glycyrrhizae Preparata 30 grams, the Radix Astragali 10 grams; Radix Angelicae Sinensis 15 grams;

Poria 10 grams; Caulis Spatholobi 50 grams; The Radix Aucklandiae 15 grams.

Embodiment three:

Colla Corii Asini 24 grams; Colla cornus cervi 5 grams; Colla Plastri Testudinis 20 grams; Radix Ginseng 10 grams;

Radix Salviae Miltiorrhizae 50 grams; Fructus Lycii 10 grams; Herba Epimedii 80 grams; Fructus Psoraleae 15 grams; Fructus Schisandrae Chinensis 35 grams;

The Rhizoma Atractylodis Macrocephalae 15 grams; Radix Glycyrrhizae Preparata 10 grams; The Radix Astragali 60 grams; Radix Angelicae Sinensis 30 grams;

Poria 25 grams; Caulis Spatholobi 80 grams; The Radix Aucklandiae 5 grams.

Claims

1, a kind of Chinese medicine of kidney and spleen invigorating hemopoietic is characterized in that it is made by the following weight proportion raw material: Colla Corii Asini 5-30 gram, Colla cornus cervi 5-30 gram, Colla Plastri Testudinis 5-30 gram, Radix Ginseng 5-30 gram, Radix Salviae Miltiorrhizae 10-50 gram, Fructus Lycii 10-50 gram, Herba Epimedii 10-100 gram, Fructus Psoraleae 10-30 gram, Fructus Schisandrae Chinensis 10-50 gram, Rhizoma Atractylodis Macrocephalae 5-30 gram, Radix Glycyrrhizae Preparata 5-30 gram, Radix Astragali 10-100 gram, Radix Angelicae Sinensis 5-30 gram, Poria 5-40 gram, Caulis Spatholobi 30-100 gram, Radix Aucklandiae 5-30 gram.

2, the preparation method of the medicine of claim 1 is characterized in that adopting following preparation technology:

A, preparation percolate: Radix Ginseng, Radix Salviae Miltiorrhizae, Herba Epimedii, Fructus Psoraleae, Fructus Schisandrae Chinensis, Poria Six-element medicine are made 80 order granularities, adding concentration is that 60% ethanol soaked 72 hours at normal temperatures, prepare percolate with percolation, reclaim ethanol, the ratio that is concentrated into 50 ℃ of relative densities then and is water and institute pastille density is 1: 1.8;

B, preparation volatile oil:, prepare volatile oil with the way of distillation, extraction time 5-6 hour with the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, the Radix Aucklandiae three flavor medicines;

C, preparation decocting liquid: Fructus Lycii, Radix Glycyrrhizae Preparata, the Radix Astragali, Caulis Spatholobi four Chinese medicine are added decocting become decocting liquid, add decocting again after pouring out decocting liquid, fry in shallow oil each 40 minutes altogether three times; When decocting for the third time, add the medicinal residues behind the percolation among the technology a, and the medicinal residues that technology b extracts behind the volatile oil are fried in shallow oil altogether; Three decocting liquids are merged, and relative density is 1: 1 a decocting liquid during 50 ℃ of simmer down tos; Add 2 times of concentration by volume 95% ethanol, left standstill 24 hours, filter and remove residue reclaims ethanol;

D, three glue moltens: with Colla Corii Asini, Colla cornus cervi, Colla Plastri Testudinis three flavor connective water heating, making its molten is jelly.

E, preparation mixed liquor: will mix at normal temperatures with the percolate of technology a preparation, the volatile oil of technology b preparation, the decocting liquid of technology c preparation, the molten jelly of technology d preparation, relative density is 1: 1.8 a mixed liquor when filtration, simmer down to 50 C, regulate pH value and make it reach PH4.5, carry out packing, sterilization then.