CN1413730A - Shugan injection and its preparation technology - Google Patents
Shugan injection and its preparation technology Download PDFInfo
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- CN1413730A CN1413730A CN 02134005 CN02134005A CN1413730A CN 1413730 A CN1413730 A CN 1413730A CN 02134005 CN02134005 CN 02134005 CN 02134005 A CN02134005 A CN 02134005A CN 1413730 A CN1413730 A CN 1413730A
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- China
- Prior art keywords
- injection
- extract
- radix scutellariae
- ganoderma
- radix
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Abstract
A Chinese medicine in the form of injection of lowering icterus, improving immunity and protecting liver is prepared from 5 Chinese-medicinal materials including oriental wormwood, capejasmine fruit, scutellaria root, etc through mixing and filter. Its advantages are high curative effect, quickly taking its effect, and no toxic by-effect.
Description
Technical field:
The present invention relates to a kind of injection and production technology thereof for the treatment of hepatopathy.
Technical background:
Hepatitis is a kind of commonly encountered diseases, and one of its topmost infringement is hepatocellular destruction or disintegrate, and the result causes the rapid increase of Serum ALT and serum bilirubin (SB), impels hepatocyte conversely again over-burden until damaging and the enzyme poisoning of each organ of whole body.Therefore reduce ALT and bilirubin and become the problem that the treatment hepatitis medicament mainly solves.But at present domestic medicine, particularly Chinese medicine generally all be oral solid formulations such as tablet, capsule, and these medicines all exist and take effect slowly, and the course of treatment, problem such as length, price height can not be that the patient is used well.
Summary of the invention:
The objective of the invention is to: a kind of good effect, instant effect are provided, have no side effect, safe and reliable, moderate pure Chinese medicine injection, to overcome the deficiencies in the prior art.
The present invention is achieved in that it is formulated with Herba Artemisiae Scopariae, Fructus Gardeniae, Radix Scutellariae, Radix Isatidis, Ganoderma, and the consumption of the every 1000ml of said components is: Herba Artemisiae Scopariae extract 4g, Fructus Gardeniae extract 3g, Radix Scutellariae extract 22g, Radix Isatidis extract 5g, Ganoderma 3.5g.
Its production technology is: get Radix Scutellariae extract and add an amount of suspendible of injection water, with the dissolving of 10% sodium hydroxide solution, after Herba Artemisiae Scopariae, Fructus Gardeniae, Radix Isatidis, Ganoderma extract mother solution being merged again, with Radix Scutellariae extract solution mixing, it is an amount of to add the injection water, adds 0.2% active carbon and stirs evenly, and boils 15 minutes, filter, regulate pH value 7.2～7.9, be diluted to 1000ml, filter with water for injection, embedding is sterilized 45 minutes promptly for 100 ℃.
The present invention compared with prior art has following advantage:
1, can promote bile secretion, the enzyme conversion reaction reduces rapidly and removes Serum ALT, AST and bilirubinic content, alleviates the hepatocyte burden, avoids hepatocyte further to damage, and alleviates the toxic reaction of whole body simultaneously, improves body function;
2, can improve the liver blood circulation, promote the hepatocyte metabolism, especially improve hepatocellular oxygen-resistant ability, strengthen autoimmunity.The experiment proved that the present invention is to CCL
4And the galactose hepatocyte of bringing out damages significant inhibitory effect arranged, and particularly hepatocellular degeneration, necrosis and inflammatory cell infiltration had significantly to alleviate effect.The effective ingredient such as Fructus Gardeniae that the present invention contained also have blocking-up or reverse the Fibrotic effect of hepatocyte;
3, can obviously improve body's immunological function, especially active ingredient such as Ganoderma is by regulating and improving central nervous system unify neuro excitement and inhibition, thereby strengthen neural---the regulating action of body fluid, the human body immunity improving system, particularly the activity of cellular immunization and humoral immunization is resisted the further infringement of virus.Reach the purpose of improving clinical symptoms, accelerating sick clear recovery.Tissue slice confirms, its total white blood cells and lymphocyte number average significantly increase, especially improve the positive percentage of investigation mission outside the city or town blood lymphocytes, immunoreation due to the hydrocortisone there is inhibitory action, but and the antivirus action of inducement interferon, show that the present invention is many-sided in the enhancing human body immunity function;
Medicine active ingredients such as the Radix Isatidis that 4, the present invention contained, Radix Scutellariae, has the effect that suppresses virus and toxic reaction thereof, and improving Abwehrkraft des Koepers, promoting under the multiple influence of immunocompetence, inducement interferon, common performance suppresses virus, the effect that alleviates hepatocellular damage; The present invention improves significantly to the myocardial ischemia that is subjected to virus infringement, especially to improving myocardial hypoxia tolerance remarkable enhancing is arranged, thereby heart tonifying, diuresis, is beneficial to jaundice eliminating; And by regulating neuro function reduction elevated blood pressure; Alleviate portal vein pressure, improve liver blood and follow; The present invention also has stronger inhibitory action to bacterial infections such as golden Portugal bacterium, Bacillus typhi, escherichia coli.
The specific embodiment:
Embodiments of the invention: to produce the 1000ml injection is example, get Radix Scutellariae extract 22g and add an amount of suspendible of injection water, dissolve with 10% sodium hydroxide solution, after again Herba Artemisiae Scopariae extract 4g, Fructus Gardeniae extract 3g, Radix Isatidis extract 5g, Ganoderma extract 3.5g mother solution being merged, with Radix Scutellariae extract solution mixing, it is an amount of to add the injection water, adds 0.2% active carbon and stirs evenly, and boils 15 minutes, filter, regulate pH value 7.2～7.9, be diluted to 1000ml, filter with water for injection, embedding, 100 ℃ the sterilization 45 minutes, through lamp inspection, lettering, pack finished product.
Claims (2)
1, a kind of soothing liver-QI injection, it is formulated with Herba Artemisiae Scopariae, Fructus Gardeniae, Radix Scutellariae, Radix Isatidis, Ganoderma, it is characterized in that: the consumption of the every 1000ml of said components is: Herba Artemisiae Scopariae extract 4g, Fructus Gardeniae extract 3g, Radix Scutellariae extract 22g, Radix Isatidis extract 5g, Ganoderma 3.5g.
2, a kind of production technology of soothing liver-QI injection is characterized in that: get Radix Scutellariae extract and add an amount of suspendible of injection water, dissolve with 10% sodium hydroxide solution, after Herba Artemisiae Scopariae, Fructus Gardeniae, Radix Isatidis, Ganoderma extract mother solution being merged, with Radix Scutellariae extract solution mixing, it is an amount of to add the injection water again, adding 0.2% active carbon stirs evenly, boiled 15 minutes, and filtered, regulate pH value 7.2～7.9, be diluted to 1000ml with water for injection, filter, embedding is sterilized 45 minutes promptly for 100 ℃.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02134005 CN1413730A (en) | 2002-11-01 | 2002-11-01 | Shugan injection and its preparation technology |
| CN 200310103393 CN1186091C (en) | 2002-11-01 | 2003-10-31 | Chinese medicine injection and its production process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02134005 CN1413730A (en) | 2002-11-01 | 2002-11-01 | Shugan injection and its preparation technology |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1413730A true CN1413730A (en) | 2003-04-30 |
Family
ID=4747509
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 02134005 Pending CN1413730A (en) | 2002-11-01 | 2002-11-01 | Shugan injection and its preparation technology |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1413730A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105412294A (en) * | 2015-12-21 | 2016-03-23 | 贵州瑞和制药有限公司龙里药厂 | Production method of Shuganning Preparation |
| CN105412295A (en) * | 2015-12-21 | 2016-03-23 | 贵州瑞和制药有限公司龙里药厂 | Production process of Shuganning Preparation |
| CN105434342A (en) * | 2015-12-21 | 2016-03-30 | 贵州瑞和制药有限公司龙里药厂 | Preparation method for Shuganning injection preparation |
-
2002
- 2002-11-01 CN CN 02134005 patent/CN1413730A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105412294A (en) * | 2015-12-21 | 2016-03-23 | 贵州瑞和制药有限公司龙里药厂 | Production method of Shuganning Preparation |
| CN105412295A (en) * | 2015-12-21 | 2016-03-23 | 贵州瑞和制药有限公司龙里药厂 | Production process of Shuganning Preparation |
| CN105434342A (en) * | 2015-12-21 | 2016-03-30 | 贵州瑞和制药有限公司龙里药厂 | Preparation method for Shuganning injection preparation |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |