CN1408376A - Oral composition for increasing bone density, and its preparing method and use - Google Patents
Oral composition for increasing bone density, and its preparing method and use Download PDFInfo
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- CN1408376A CN1408376A CN 01126829 CN01126829A CN1408376A CN 1408376 A CN1408376 A CN 1408376A CN 01126829 CN01126829 CN 01126829 CN 01126829 A CN01126829 A CN 01126829A CN 1408376 A CN1408376 A CN 1408376A
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Abstract
The oral liquid for increasing bone density is prepared with animal connective tissue, ephedra and water in the ratio of 1 to 0.08-0.13 to 0.5-1.8 and through maintaining inside a reactor at 3.5-7 atm and 110-200 deg.c for 1-7 hr. The present invention also relates to the preparation process of the oral liquid and its use in increasing bone density.
Description
Technical field
The present invention relates to a kind of Orally administered composition of energy bone density improving, and preparation method thereof.
Background technology
Human skeleton is made up of mineral such as organic (collagen protein, keratin, fibrin) and calcium phosphorus, organic popular name osseocolla, belong to indigestion albumen, the baby is by enzyme glandular secretion liquid such as pancreas enzyme abundant in its gastric juice, pepsin, Chymotrypsin, digest and assimilate the organic matter in the breast milk, get so that growing.With advancing age, body aging and the change of digesting and assimilating food variety, the secretion of above-mentioned enzyme gland reduces day by day in adult's gastric juice, and especially the old man more than 60 years old is owing to reduce above-mentioned proteic absorption, and causes osteoporosis.
Red bone marrow has hemopoietic function, so being in the bone marrow of child's whole body of stage of development all is red bone marrow, with advancing age with the increase of extremity loading, red bone marrow in the long bone bone cavity just changes yellow bone marrow (belonging to lipoid material) gradually into, to strengthen the support force of body to the work load amount.Red bone marrow belongs to collagen protein, except that hemopoietic function, or the full material of the bonding material of grey matter calcium and honeycomb intracavity.In case the absorbtivity to collagen protein in the food reduces, and can't compensate the losing quantity of collagen protein in the sclerotin, osteoporosis will occur, is easy to fracture, and be difficult to healing.
The contained number of chemical compositions such as intermolecular peptide bond, hydrogen bond, disulfide bond that contain above-mentioned some protein in view of the fresh connective tissue of animals such as Os Bovis seu Bubali, Os Sus domestica, Bauhinia variegata Linn are difficult to drop into simultaneously with stove and decompose with several different chemical reagent targetedly.Otherwise, neutralization that certainly will factor kind chemical agent and lose the effect of breaking up chemical bonds.If with ready-made trypsin or pepsin its chemical bond that ruptures, the material that is decomposed per ton will cost 1.6 ten thousand dollars.The number of chemical key if gradation goes to rupture, its heat energy, electric power, artificial consume repeatedly also are huge the manyfolds that exceeds the finished product valency, and another difficulty is exactly can not ceaselessly separate down the decomposition of chemical bond.Otherwise the effective ingredient of its fracture material is with having nothing at all of being decomposed.Thereby the input of its decomposed substance can only be limited to and only can divide till its elementary key and the secondary key.
Therefore, the present technique field is sought after a kind of oral liquid of bone density improving, and its production cost is low, easy and simple to handle, with short production cycle, be easy to batch production produces preparation.
Herba Ephedrae is a kind of Chinese herbal medicine, and it can be used for treating the disease of aspects such as cough with asthma, and never report mentions that Herba Ephedrae can be used for decomposing animal connective tissue.
Summary of the invention
An object of the present invention is to provide a kind of oral liquid of energy bone density improving.
Another object of the present invention provides the method for the described oral liquid of preparation, and its characteristics are that cost is low, easy and simple to handle, with short production cycle, are easy to batch production production.
A further object of the present invention is the purposes of described oral liquid.
Above-mentioned purpose of the present invention realizes by following design: a kind of oral liquid, and it obtains by following method:
Weight ratio 10 with animal connective tissue and Herba Ephedrae: 0.8-10: 1.3 ratio drops into reactor, and be 1 with the weight ratio of animal connective tissue and water: 0.5-1: 1.8 ratio adds entry, below 3.5-7 atmospheric pressure, 110-200 ℃, keeps 1-7 hour.
A kind of method for preparing described oral liquid, comprise: with the weight ratio 10 of animal connective tissue and Herba Ephedrae: 0.8-10: 1.3 ratio drops into reactor, weight ratio with animal connective tissue and water is 1: 0.5-1: 1.8 ratio adds entry, below 3.5-7 atmospheric pressure, 110-200 ℃, kept 1-7 hour.
Described animal connective tissue is selected from fresh Os Bovis seu Bubali, Os Sus domestica and Bauhinia variegata Linn, preferably fresh Os Bovis seu Bubali.
Raw materials such as preferred animal connective tissue is clean, decontamination, chopping then.
The invention further relates to the application of described oral liquid in the health product of preparation bone density improving.
The specific embodiment
To do further detailed elaboration to the present invention by embodiment below.
Embodiment 1
Choosing the cattle rib cleans for 10 kilograms, decontamination, chopping, input is cleaned, the disinfectant reactor (close celebrating pressure and hold factory by Shanghai, 97-223, capacity 40cm * 70cm), add 1 kilogram Herba Ephedrae again adds 3 kilograms pure distilled water then, seal then, be heated to 5 atmospheric pressure, below 160-170 ℃, kept 6 hours.
After the screw of reactor turned on one by one, take out material in it, these materials are filtered again, the material after will filtering then is placed on 18 ℃ and assigned 2 hours, refilters except that degrease, obtains the thick thing of brownish red, promptly obtains concentrate of the present invention.
Test 1:
The product of embodiment 1 gained is tested through Shanghai Inst. of Biochemistry, Chinese Academy of Sciences, obtains following result:
Analyze pre-treatment: 6N HCI, 110 ℃, hydrolysis in 18 hours
Sample concentration: consumption during the 0.2ml/100ml sample analysis: 0.05 milliliter
Analysis result
(each amino acid content when following data are sample analysis in the consumption)
| Aminoacid | Mg/ml | Aminoacid | Mg/ml |
| Taurine | Different bright Ile | ????3.18 | |
| Radix Asparagi Asp | ????8.05 | Bright Leu | ????8.17 |
| The Thr of Soviet Union | ????2.86 | Cheese Tyr | ????2.44 |
| Silk Ser | ????3.49 | Phenylpropyl alcohol Phe | ????4.65 |
| Paddy Glu | ????20.82 | Bird ORN | ????1.22 |
| Dried meat Pro | ????13.65 | Rely Lys | ????5.41 |
| Sweet Gly | ????23.25 | Ammonia NH 3 | |
| Third Ala | ????13.13 | Group His | ????1.30 |
| Guang Cys | ????0.85 | Color Try | |
| Figured silk fabrics Val | ????5.33 | Smart Arg | ????10.69 |
| First sulfur Met | ????2.63 |
Test 2:
The concentrate of embodiment 1 preparation is pressed 1 with distilled water: the dilution proportion of 20-40,500 milliliters/bottle standby.
1) women, 53 years old, Fracture of femur in 1997, lying up and taking medicine reaches 2 months, the commentaries on classics of not getting better of fracturing.Oral afterwards oral liquid of the present invention, 10 milliliters/time, every day 2 times, take 2 months after, the fracture substantially the healing, crossed a wheat harvesting period again and recovered normal fully.
2) women, 65 years old, suffer from serious arthritis and osteoporosis all the year round, oral liquid of the present invention is taken 2 times with 10 milliliters of/time dosage every day in the back, and after 3 months, sensation spirit is fine, and pain alleviates to some extent, and the sleep at night is also better than in the past.
3) women, 71 years old, two gonalgia 8 years were surplus, pain during existing walk, winter pain more, be " two knee joint hyperosteogenys " through diagnosis, difficulty is felt in back walking, two knee joint swelling distortion, External knee protector, tendon reflex goes down, activity is stretched in the wrong, about revolve and be obstructed, the back is with 10 milliliters of/time dosage, take oral liquid of the present invention 2 times every day, take 10 days after, the patient feels two knee joint pain reliefs, 1 bottle take after, the patient feel on foot more preceding easily, it is normal that two knee jerks recover.This shows that Orally administered composition of the present invention changes effective in cure to old degeneration.
Claims (7)
1, a kind of oral liquid, it obtains by following method:
Weight ratio 10 with animal connective tissue and Herba Ephedrae: 0.8-10: 1.3 ratio drops into reactor, and be 1 with the weight ratio of animal connective tissue and water: 0.5-1: 1.8 ratio adds entry, below 3.5-7 atmospheric pressure, 110-200 ℃, keeps 1-7 hour.
2, oral liquid according to claim 1, wherein said animal connective tissue is selected from fresh Os Bovis seu Bubali, Os Sus domestica and Bauhinia variegata Linn.
3, oral liquid according to claim 2, wherein said animal connective tissue is fresh Os Bovis seu Bubali.
4, oral liquid according to claim 1, wherein the weight ratio of animal connective tissue and Herba Ephedrae is 10: 1.
5, a kind of preparation method of oral liquid according to claim 1, comprise: with the weight ratio 10 of animal connective tissue and Herba Ephedrae: 0.8-10: 1.3 ratio drops into reactor, weight ratio with animal connective tissue and water is 1: 0.5-1: 1.8 ratio adds entry, below 3.5-7 atmospheric pressure, 110-200 ℃, kept 1-7 hour.
6, preparation method according to claim 5, before with animal connective tissue and Herba Ephedrae input reactor, this method also comprises raw materials such as animal connective tissue is clean, decontamination, Qie Sui step then.
7, the purposes of oral liquid as claimed in claim 1 in the health product of preparation bone density improving.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01126829 CN1408376A (en) | 2001-09-21 | 2001-09-21 | Oral composition for increasing bone density, and its preparing method and use |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01126829 CN1408376A (en) | 2001-09-21 | 2001-09-21 | Oral composition for increasing bone density, and its preparing method and use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1408376A true CN1408376A (en) | 2003-04-09 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 01126829 Pending CN1408376A (en) | 2001-09-21 | 2001-09-21 | Oral composition for increasing bone density, and its preparing method and use |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100391474C (en) * | 2006-06-13 | 2008-06-04 | 卢建军 | Injection medicine for treating platelet abatement |
| CN103445154A (en) * | 2013-07-31 | 2013-12-18 | 宫中林 | Compound ox bone oral liquid for muscles and bones |
-
2001
- 2001-09-21 CN CN 01126829 patent/CN1408376A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100391474C (en) * | 2006-06-13 | 2008-06-04 | 卢建军 | Injection medicine for treating platelet abatement |
| CN103445154A (en) * | 2013-07-31 | 2013-12-18 | 宫中林 | Compound ox bone oral liquid for muscles and bones |
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