CN1394140A - 前列腺素组合物和治疗男性勃起机能障碍的方法 - Google Patents

前列腺素组合物和治疗男性勃起机能障碍的方法 Download PDF

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Publication number
CN1394140A
CN1394140A CN01803447A CN01803447A CN1394140A CN 1394140 A CN1394140 A CN 1394140A CN 01803447 A CN01803447 A CN 01803447A CN 01803447 A CN01803447 A CN 01803447A CN 1394140 A CN1394140 A CN 1394140A
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CN
China
Prior art keywords
compositions
group
prostaglandin
mixture
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN01803447A
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English (en)
Chinese (zh)
Inventor
詹姆斯·亚格
那迪·布亚迪金
瑟维特·布亚迪金
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Nexmed Holdings Inc
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Nexmed Holdings Inc
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23909154&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1394140(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nexmed Holdings Inc filed Critical Nexmed Holdings Inc
Publication of CN1394140A publication Critical patent/CN1394140A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
CN01803447A 2000-01-10 2001-01-10 前列腺素组合物和治疗男性勃起机能障碍的方法 Pending CN1394140A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/480,738 2000-01-10
US09/480,738 US6323241B1 (en) 2000-01-10 2000-01-10 Prostaglandin compositions and methods of treatment for male erectile dysfunction

Publications (1)

Publication Number Publication Date
CN1394140A true CN1394140A (zh) 2003-01-29

Family

ID=23909154

Family Applications (1)

Application Number Title Priority Date Filing Date
CN01803447A Pending CN1394140A (zh) 2000-01-10 2001-01-10 前列腺素组合物和治疗男性勃起机能障碍的方法

Country Status (20)

Country Link
US (1) US6323241B1 (https=)
EP (1) EP1255552B1 (https=)
JP (2) JP2003519657A (https=)
KR (1) KR100614361B1 (https=)
CN (1) CN1394140A (https=)
AT (1) ATE290383T1 (https=)
AU (1) AU760576C (https=)
BE (1) BE2014C001I2 (https=)
BR (1) BR0107478A (https=)
CA (1) CA2395217C (https=)
DE (1) DE60109274T2 (https=)
ES (1) ES2236245T3 (https=)
HK (1) HK1047700B (https=)
HU (1) HUP0204159A3 (https=)
IL (2) IL150306A0 (https=)
MX (1) MXPA02006758A (https=)
PT (1) PT1255552E (https=)
TR (1) TR200201769T2 (https=)
WO (1) WO2001051053A1 (https=)
ZA (1) ZA200205433B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1761461B (zh) * 2003-03-21 2010-05-05 奈克斯麦德控股有限公司 前列腺素组合物在制备治疗早泄的药物中的应用

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GR1002847B (el) 1997-05-06 1998-01-27 Χρηση της μισοπροστολης ή/και της μισοπροστολης οξυ για την παρασκευη φαρμακευτικου προιοντος για τη θεραπευτικη αντιμετωπιση των δυσλειτουργιων της στυσεως
US6414028B1 (en) * 1997-11-05 2002-07-02 Nexmed Holdings, Inc. Topical compositions containing prostaglandin E1
US20050004226A1 (en) * 1998-12-10 2005-01-06 Nexmed (Holdings), Inc. Compositions and methods for amelioration of human female sexual dysfunction
US6825234B2 (en) 1998-12-10 2004-11-30 Nexmed (Holdings) , Inc. Compositions and methods for amelioration of human female sexual dysfunction
EA008720B1 (ru) * 1998-12-10 2007-06-29 Нексмед (Холдингс), Инк. Применение композиции на основе простагландина для лечения расстройства сексуального возбуждения у женщин
US6693135B2 (en) * 2000-01-10 2004-02-17 Nexmed (Holdings) Incorporated Prostaglandin compositions and methods of treatment for male erectile dysfunction
US7105571B2 (en) * 2000-01-10 2006-09-12 Nexmed Holdings, Inc. Prostaglandin compositions and methods of treatment for male erectile dysfunction
US20040110843A1 (en) * 2000-01-10 2004-06-10 Nexmed (Holdings), Inc. Methods of treatment of male erectile dysfunction
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
US20090035221A1 (en) * 2002-01-25 2009-02-05 Ramsey Sallis Methods and Compositions for Treatment of Erectile Dysfunction
US20090257956A1 (en) * 2002-01-25 2009-10-15 Ramsey Sallis Treatment Method for Treatment of Erectile Dysfunction and Premature Ejaculation
WO2003063776A2 (en) 2002-01-25 2003-08-07 Modular Properties Ltd Methods and compositions for treating male erectile dysfunction
MXPA04007828A (es) * 2002-02-15 2004-10-15 Nexmed Holdings Inc Composicion de prostaglandina para eltratamiento de la disfuncion erectil.
JP2006512291A (ja) * 2002-09-06 2006-04-13 ネックスメド ホールディングス インコーポレイテッド 男性勃起障害の治療方法
GB0222522D0 (en) 2002-09-27 2002-11-06 Controlled Therapeutics Sct Water-swellable polymers
US6841574B2 (en) * 2003-01-03 2005-01-11 Nexmed Holdings, Inc. Topical stabilized prostaglandin E compound dosage forms
EP1605913A2 (en) * 2003-03-21 2005-12-21 Nexmed (Holdings), Inc. Angiogenesis promotion by prostaglandin compositions and methods
EP1605948A1 (en) * 2003-03-21 2005-12-21 Nexmed Holdings, Inc. Prostaglandin compositions for the treatment of erectile dysfunction
EP1608378A1 (en) * 2003-04-02 2005-12-28 Nexmed (Holdings), Inc. Prostaglandin compositions and their use for the treatment of vasospasm
US20050159985A1 (en) * 2003-11-21 2005-07-21 Bertram Carl T. System and method of stratifying intervention groups and comparison groups based on disease severity index scores and ranges
GB0417401D0 (en) 2004-08-05 2004-09-08 Controlled Therapeutics Sct Stabilised prostaglandin composition
US7655659B2 (en) * 2004-08-19 2010-02-02 Applied Genetics Incorporated Dermatics Biomimetic of Evodia rutaecarpa fruit extract for amelioration of inflammation
GB0613333D0 (en) 2006-07-05 2006-08-16 Controlled Therapeutics Sct Hydrophilic polyurethane compositions
GB0613638D0 (en) 2006-07-08 2006-08-16 Controlled Therapeutics Sct Polyurethane elastomers
GB0620685D0 (en) 2006-10-18 2006-11-29 Controlled Therapeutics Sct Bioresorbable polymers
US9005183B2 (en) * 2007-05-16 2015-04-14 Health Knight, Llc System and method for treating erectile dysfunction
NZ609826A (en) * 2010-12-02 2016-03-31 Nexmed Holdings Inc Active enantiomer of dodecyl 2-(n,n-dimethylamino)-propionate
RU2633236C2 (ru) 2011-04-07 2017-10-11 Нексмед Холдингс, Инк. Способы и композиции для лечения болезни рейно
US10226418B2 (en) 2014-05-12 2019-03-12 Susie Q, Ltd. Arginine-containing topical composition
EP3247357A4 (en) 2015-01-20 2018-07-11 Xoc Pharmaceuticals, Inc Isoergoline compounds and uses thereof
MX2017009405A (es) 2015-01-20 2018-01-18 Xoc Pharmaceuticals Inc Compuestos de tipo ergolina y usos de estos.
EP3266458A1 (en) 2016-07-05 2018-01-10 Fagron B.V. Method and composition and kit for treating erectile dysfunction
WO2018223065A1 (en) 2017-06-01 2018-12-06 Xoc Pharmaceuticals, Inc. Ergoline derivatives for use in medicine
USD1122263S1 (en) * 2023-02-15 2026-04-14 Amadeus S.A.S. Display screen with animated graphical user interface

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1761461B (zh) * 2003-03-21 2010-05-05 奈克斯麦德控股有限公司 前列腺素组合物在制备治疗早泄的药物中的应用

Also Published As

Publication number Publication date
ES2236245T3 (es) 2005-07-16
ATE290383T1 (de) 2005-03-15
DE60109274D1 (de) 2005-04-14
BR0107478A (pt) 2002-09-03
BE2014C001I2 (https=) 2020-01-30
AU2934901A (en) 2001-07-24
AU760576C (en) 2004-04-08
DE60109274T2 (de) 2006-02-09
EP1255552B1 (en) 2005-03-09
IL150306A (en) 2007-06-03
KR100614361B1 (ko) 2006-08-18
JP2007302690A (ja) 2007-11-22
CA2395217C (en) 2004-10-26
JP2003519657A (ja) 2003-06-24
EP1255552A1 (en) 2002-11-13
TR200201769T2 (tr) 2002-11-21
HUP0204159A3 (en) 2005-03-29
WO2001051053A1 (en) 2001-07-19
HK1047700A1 (en) 2003-03-07
US6323241B1 (en) 2001-11-27
ZA200205433B (en) 2003-11-26
KR20020073498A (ko) 2002-09-26
CA2395217A1 (en) 2001-07-19
HUP0204159A2 (hu) 2003-04-28
HK1047700B (en) 2005-05-27
MXPA02006758A (es) 2008-09-12
AU760576B2 (en) 2003-05-15
IL150306A0 (en) 2002-12-01
PT1255552E (pt) 2005-06-30

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