CN1379670A - 傅立叶变换拉曼光谱术测量组合物中奥美拉唑异构体的比例 - Google Patents

傅立叶变换拉曼光谱术测量组合物中奥美拉唑异构体的比例 Download PDF

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Publication number
CN1379670A
CN1379670A CN00814398A CN00814398A CN1379670A CN 1379670 A CN1379670 A CN 1379670A CN 00814398 A CN00814398 A CN 00814398A CN 00814398 A CN00814398 A CN 00814398A CN 1379670 A CN1379670 A CN 1379670A
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CN
China
Prior art keywords
methoxyl group
omeprazole
isomer
ratio
pharmaceutical formulation
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Pending
Application number
CN00814398A
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English (en)
Chinese (zh)
Inventor
R·R·怀特勒
F·D·桑茨利奥
G·W·斯托维尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AAIPharma Inc
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Applied Analytical Industries Inc
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Application filed by Applied Analytical Industries Inc filed Critical Applied Analytical Industries Inc
Publication of CN1379670A publication Critical patent/CN1379670A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CN00814398A 1999-08-26 2000-08-23 傅立叶变换拉曼光谱术测量组合物中奥美拉唑异构体的比例 Pending CN1379670A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15087899P 1999-08-26 1999-08-26
US60/150,878 1999-08-26

Publications (1)

Publication Number Publication Date
CN1379670A true CN1379670A (zh) 2002-11-13

Family

ID=22536394

Family Applications (2)

Application Number Title Priority Date Filing Date
CN00814398A Pending CN1379670A (zh) 1999-08-26 2000-08-23 傅立叶变换拉曼光谱术测量组合物中奥美拉唑异构体的比例
CNA2006101016924A Pending CN1880312A (zh) 1999-08-26 2000-08-25 烷氧基取代苯并咪唑化合物和含它们的组合物及药物制剂

Family Applications After (1)

Application Number Title Priority Date Filing Date
CNA2006101016924A Pending CN1880312A (zh) 1999-08-26 2000-08-25 烷氧基取代苯并咪唑化合物和含它们的组合物及药物制剂

Country Status (10)

Country Link
US (1) US20060014799A1 (https=)
EP (1) EP1206263A1 (https=)
JP (1) JP2003507721A (https=)
KR (1) KR20020043565A (https=)
CN (2) CN1379670A (https=)
AU (1) AU6937700A (https=)
CA (1) CA2382838A1 (https=)
MX (1) MXPA02002068A (https=)
WO (1) WO2001013919A1 (https=)
ZA (2) ZA200201519B (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113092445A (zh) * 2021-04-14 2021-07-09 中朗正健(苏州)生物技术有限公司 一种对减肥类保健食品中违法添加奥美拉唑的检测方法

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
CA2443605A1 (en) * 2001-04-20 2002-10-31 Linda Whittall Process for purifying 6-methoxy omeprazole
US7855082B1 (en) 2001-10-31 2010-12-21 Astrazeneca Ab Raman spectroscopic method for determining the ratio of 5-methoxy and 6-methoxy isomers of omeprazole
DE10322439A1 (de) * 2003-05-19 2004-12-09 Bayer Ag Verfahren und Vorrichtung zur Bestimmung der Isomerenzusammensetzung bei Isocyanat-Herstellprozessen
FR2937418B1 (fr) * 2008-10-17 2010-12-31 France Etat Ponts Chaussees Procede de determination de la phase solide/liquide.
MX2013003038A (es) * 2010-09-17 2013-05-01 Abbvie Inc Espectroscopia raman para operaciones de bioprocesos.
CN103833731B (zh) * 2011-12-01 2016-03-23 四川大学 手性亚砜类化合物及其盐的制备新方法和晶型
CN103006610B (zh) * 2013-01-04 2014-10-22 青岛大学 一种埃索美拉唑钠肠溶片剂及其制备方法
CN103408532A (zh) * 2013-08-02 2013-11-27 常州大学 一种质子泵抑制剂的制备方法
US9599565B1 (en) * 2013-10-02 2017-03-21 Ondax, Inc. Identification and analysis of materials and molecular structures
US9587983B1 (en) 2015-09-21 2017-03-07 Ondax, Inc. Thermally compensated optical probe
EP3472582A4 (en) * 2016-06-16 2020-03-18 Valisure LLC SPECTROSCOPIC ANALYSIS METHODS AND SYSTEMS

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US5638172A (en) * 1994-05-27 1997-06-10 Eastman Chemical Company On-line quantitative analysis of chemical compositions by raman spectrometry
US6040906A (en) * 1996-07-11 2000-03-21 Harhay; Gregory P. Resonance raman spectroscopy for identifying and quantitating biomatter, organic, and inorganic analytes
US5850623A (en) * 1997-03-14 1998-12-15 Eastman Chemical Company Method for standardizing raman spectrometers to obtain stable and transferable calibrations

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113092445A (zh) * 2021-04-14 2021-07-09 中朗正健(苏州)生物技术有限公司 一种对减肥类保健食品中违法添加奥美拉唑的检测方法

Also Published As

Publication number Publication date
ZA200201521B (en) 2003-05-22
JP2003507721A (ja) 2003-02-25
EP1206263A1 (en) 2002-05-22
US20060014799A1 (en) 2006-01-19
WO2001013919A1 (en) 2001-03-01
MXPA02002068A (es) 2003-08-20
CA2382838A1 (en) 2001-03-01
KR20020043565A (ko) 2002-06-10
AU6937700A (en) 2001-03-19
CN1880312A (zh) 2006-12-20
ZA200201519B (en) 2003-05-22

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