CN1321114C - 一种奥利司他的制备方法 - Google Patents
一种奥利司他的制备方法 Download PDFInfo
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- CN1321114C CN1321114C CNB2005101104136A CN200510110413A CN1321114C CN 1321114 C CN1321114 C CN 1321114C CN B2005101104136 A CNB2005101104136 A CN B2005101104136A CN 200510110413 A CN200510110413 A CN 200510110413A CN 1321114 C CN1321114 C CN 1321114C
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Priority Applications (1)
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CNB2005101104136A CN1321114C (zh) | 2005-11-16 | 2005-11-16 | 一种奥利司他的制备方法 |
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CNB2005101104136A CN1321114C (zh) | 2005-11-16 | 2005-11-16 | 一种奥利司他的制备方法 |
Publications (2)
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CN1765892A CN1765892A (zh) | 2006-05-03 |
CN1321114C true CN1321114C (zh) | 2007-06-13 |
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CNB2005101104136A Expired - Fee Related CN1321114C (zh) | 2005-11-16 | 2005-11-16 | 一种奥利司他的制备方法 |
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Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
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CN101066924B (zh) * | 2007-06-08 | 2011-01-12 | 中国科学院上海有机化学研究所 | 2-己基-3-羟基-5-r1氧基十六羧酸r2酯,制备方法及用于制备减肥药物奥利司他的用途 |
CN101939308B (zh) * | 2008-05-26 | 2013-10-23 | 重庆植恩药业有限公司 | (3s,4s)-3-己基-4-((r)-2-羟基十三烷基)-环氧丁烷-2-酮的制备方法及其利用此方法制备的产品 |
CN102070567A (zh) * | 2011-01-21 | 2011-05-25 | 天津市海德安科医药科技发展有限公司 | 反相高效液相色谱制备高纯度奥利司他的方法 |
CN103012240B (zh) * | 2012-12-11 | 2015-05-27 | 保定市龙瑞药物技术有限责任公司 | 一种阿托伐他汀钙的制备方法 |
CN108484536B (zh) * | 2018-05-22 | 2021-02-02 | 东莞理工学院 | 一种减肥药奥利司他中间体的合成方法 |
CN114560887B (zh) * | 2022-02-15 | 2024-01-26 | 安徽美致诚药业有限公司 | 一种制备奥利司他的中间体的制备方法 |
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2005
- 2005-11-16 CN CNB2005101104136A patent/CN1321114C/zh not_active Expired - Fee Related
Non-Patent Citations (4)
Title |
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23.Syntheses of Tetrahydrolipstatin andAbsoluteConfiguration of Tetrahydrolipstatin and Lipstatin Pierre Barbier and Fernand Schneider,Helvetica Chimica Acta,Vol.70 No.1 1987 * |
23.Syntheses of Tetrahydrolipstatin andAbsoluteConfiguration of Tetrahydrolipstatin and Lipstatin Pierre Barbier and Fernand Schneider,Helvetica Chimica Acta,Vol.70 No.1 1987;A Stereoselective synthesis of (-)-tetrahydrolipstatin Arun K.Ghosh and Chunfeng Liu,Chem. Commun.(Cambridge),Vol.17 1999;Diastereoselective allylations and crotylationsunderphase-transferconditions using trifluoroborate salts: anapplication to thetotalsynthesis of (-)-tetrahydrolipstatin Avinash N.Thadani and Robert A. Batey,Tetrahedron Letters,Vol.44 No.44 2003 * |
A Stereoselective synthesis of (-)-tetrahydrolipstatin Arun K.Ghosh and Chunfeng Liu,Chem. Commun.(Cambridge),Vol.17 1999 * |
Diastereoselective allylations and crotylationsunderphase-transferconditions using trifluoroborate salts: anapplication to thetotalsynthesis of (-)-tetrahydrolipstatin Avinash N.Thadani and Robert A. Batey,Tetrahedron Letters,Vol.44 No.44 2003 * |
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CN1765892A (zh) | 2006-05-03 |
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