CN1304050C - 含有因子ⅶ多肽和因子ⅺ多肽的药用组合物 - Google Patents

含有因子ⅶ多肽和因子ⅺ多肽的药用组合物 Download PDF

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Publication number
CN1304050C
CN1304050C CNB028185390A CN02818539A CN1304050C CN 1304050 C CN1304050 C CN 1304050C CN B028185390 A CNB028185390 A CN B028185390A CN 02818539 A CN02818539 A CN 02818539A CN 1304050 C CN1304050 C CN 1304050C
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CN
China
Prior art keywords
factor
thromboplastin antecedent
plasma thromboplastin
polypeptide
factor vii
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CNB028185390A
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English (en)
Chinese (zh)
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CN1556710A (zh
Inventor
拉斯马斯·罗杰克杰尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk Health Care AG
Novo Nordisk AS
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Novo Nordisk AS
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Publication of CN1556710A publication Critical patent/CN1556710A/zh
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Publication of CN1304050C publication Critical patent/CN1304050C/zh
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4846Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CNB028185390A 2001-07-20 2002-07-19 含有因子ⅶ多肽和因子ⅺ多肽的药用组合物 Expired - Fee Related CN1304050C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200101127 2001-07-20
DKPA200101127 2001-07-20

Publications (2)

Publication Number Publication Date
CN1556710A CN1556710A (zh) 2004-12-22
CN1304050C true CN1304050C (zh) 2007-03-14

Family

ID=8160632

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB028185390A Expired - Fee Related CN1304050C (zh) 2001-07-20 2002-07-19 含有因子ⅶ多肽和因子ⅺ多肽的药用组合物

Country Status (16)

Country Link
EP (1) EP1411973A1 (xx)
JP (1) JP2004534855A (xx)
KR (1) KR20040015821A (xx)
CN (1) CN1304050C (xx)
AU (1) AU2002354846B2 (xx)
BR (1) BR0211256A (xx)
CA (1) CA2452677A1 (xx)
CZ (1) CZ200439A3 (xx)
HU (1) HUP0400976A3 (xx)
IL (1) IL159622A0 (xx)
MX (1) MXPA04000415A (xx)
NO (1) NO20040235L (xx)
PL (1) PL369077A1 (xx)
RU (1) RU2298416C2 (xx)
WO (1) WO2003007983A1 (xx)
ZA (1) ZA200400012B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5807500A (en) 1999-07-14 2001-02-05 Novo Nordisk A/S Use of fviia or a tissue factor antagonist for regulating gene expression and cell migration or chemotaxis
ES2381110T3 (es) 2003-09-09 2012-05-23 Novo Nordisk Health Care Ag Polipéptidos de factor VII de coagulación
BRPI0416461A (pt) * 2003-11-20 2007-03-06 Novo Nordisk Healthcare Ag método para o tratamento de episódios de sangramento, formulação farmacêutica, e, uso de um polipeptìdeo fxi
EP1713497B1 (en) * 2004-02-05 2016-04-13 Novo Nordisk Health Care AG Use of factor viia for treating late complications of trauma
WO2006128497A1 (en) * 2005-06-01 2006-12-07 Novo Nordisk A/S Pharmaceutical formulation of factor xi
ES2773766T3 (es) 2008-12-19 2020-07-14 Baxalta GmbH Inhibidores de TFPI y métodos de uso
AU2011227714B2 (en) 2010-03-19 2014-09-04 Takeda Pharmaceutical Company Limited TFPI inhibitors and methods of use
EP2624859B1 (en) 2010-10-06 2017-03-01 Medimmune Limited Factor ii alone or in combination with further factors for treatment of impaired haemostasis associated with dilutional coagulopathy
CA2867363C (en) 2012-03-21 2023-02-28 Baxter International Inc. Tfpi inhibitors and methods of use
KR20160111520A (ko) * 2014-01-31 2016-09-26 다나-파버 캔서 인스티튜트 인크. 디히드로프테리디논 유도체 및 그의 용도
EP3307728A4 (en) 2015-06-12 2019-07-17 Dana Farber Cancer Institute, Inc. ASSOCIATION THERAPY USING TRANSCRIPTION INHIBITORS AND KINASE INHIBITORS
MX2018006499A (es) 2015-11-25 2018-08-01 Dana Farber Cancer Inst Inc Inhibidores de bromodominio bivalentes y usos de los mismos.
US11958911B2 (en) 2017-02-10 2024-04-16 Shanghai Benemae Pharmaceutical Anti-coagulation factor XI antibody

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5252217A (en) * 1991-05-07 1993-10-12 Association Pour L'essor De La Transfusion Sanguine Dans La Region Du Nord Blood coagulation factor XI concentrate having high specific activity, suitable for therapeutic use, and process for preparing same
US5580560A (en) * 1989-11-13 1996-12-03 Novo Nordisk A/S Modified factor VII/VIIa

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59116213A (ja) * 1982-12-24 1984-07-05 Unitika Ltd エアゾ−ル組成物
ATE66374T1 (de) * 1985-11-26 1991-09-15 Novo Nordisk As Zubereitungen und verfahren zur behandlung von blutungsstoerungen.
JP4361728B2 (ja) * 2000-09-13 2009-11-11 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト ヒト凝固因子vii変異型

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5580560A (en) * 1989-11-13 1996-12-03 Novo Nordisk A/S Modified factor VII/VIIa
US5252217A (en) * 1991-05-07 1993-10-12 Association Pour L'essor De La Transfusion Sanguine Dans La Region Du Nord Blood coagulation factor XI concentrate having high specific activity, suitable for therapeutic use, and process for preparing same

Also Published As

Publication number Publication date
HUP0400976A2 (hu) 2004-08-30
CN1556710A (zh) 2004-12-22
AU2002354846B2 (en) 2007-08-02
IL159622A0 (en) 2004-06-01
HUP0400976A3 (en) 2006-01-30
BR0211256A (pt) 2004-07-27
ZA200400012B (en) 2004-08-17
NO20040235L (no) 2004-03-17
JP2004534855A (ja) 2004-11-18
MXPA04000415A (es) 2004-11-22
RU2004105031A (ru) 2005-04-20
CZ200439A3 (cs) 2005-03-16
RU2298416C2 (ru) 2007-05-10
PL369077A1 (en) 2005-04-18
CA2452677A1 (en) 2003-01-30
KR20040015821A (ko) 2004-02-19
EP1411973A1 (en) 2004-04-28
WO2003007983A1 (en) 2003-01-30

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