CN1289164C - Carbon dioxide supercritical extraction method for placenta extract - Google Patents
Carbon dioxide supercritical extraction method for placenta extract Download PDFInfo
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- CN1289164C CN1289164C CNB2004100969740A CN200410096974A CN1289164C CN 1289164 C CN1289164 C CN 1289164C CN B2004100969740 A CNB2004100969740 A CN B2004100969740A CN 200410096974 A CN200410096974 A CN 200410096974A CN 1289164 C CN1289164 C CN 1289164C
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- placenta
- carbon dioxide
- temperature
- extract
- supercritical extraction
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Abstract
The present invention discloses a carbon dioxide supercritical extraction method for placenta extracts. The method sequentially comprises the following steps that a placenta is frozen and dried for 5 to 6h at the temperature of-5 DEG C to-6 DEG C, and is pulverized into powder; the placenta powder is loaded in an extraction kettle, and carbon dioxide with the pressure of 30 to 40Mpa is led into the extraction kettle to extract at the temperature of 30 to 40DEGC; the secondary depressurization separation is carried out, placenta extract is prepared, and the primary depressurization separation condition has the pressure of 8 to 12Mpa and the temperature of 30 to 35 DEG C; the secondary depressurization separation condition has the pressure below 6Mpa and the temperature of 15 to 25 DEG C. The present invention has the advantage that the active ingredients extracted from the placenta extract can not be devitalized; the extraction of the placenta extract from the placenta is thorough.
Description
Technical field
The present invention relates to extract from the human placenta method of placental hormone, is a kind of method that adopts the carbon dioxide supercritical extraction technology to extract placental hormone.
Background technology
Placenta Chinese medicine is called dried human placenta, has the adjusting function of human body, can build up resistance the effect of the essence and blood that reinforces vital energy.Placental hormone is the medicinal component that extracts from placenta, contains multiple hormone and biology enzyme.At present, the decocting and concentrating method is adopted in the extraction of placental hormone more, the placental hormone amount that this method not only can extract is few, and energy consumption is big, cost is high, and some active gene regulatory factors in the placenta and part metabolic regulation enzyme can reduce the value of placental hormone because of the high temperature action inactivation.
Summary of the invention
At existing placental hormone extracting method above shortcomings, the object of the present invention is to provide a kind of new placental hormone extracting method, by the placental hormone in the carbon dioxide supercritical extraction extraction placenta, not only cost is low, and can keep the activity of bioactive ingredients in the placental hormone.
Carbon dioxide supercritical extraction method for placenta extract of the present invention in turn includes the following steps:
(1) with placenta process freeze drying 5～6h under-5 ℃～-6 ℃ conditions, pulverize;
(2) the placenta powder is packed in the extraction kettle, feed the carbon dioxide of 30～40Mpa, under 30～40 ℃ of conditions, extract;
(3) carry out second depressurized and separate, obtain placental hormone, one-level decompression separation condition is operating pressure 8～12Mpa, and temperature is 30～35 ℃; The second depressurized separation condition be operating pressure below 6Mpa, temperature is 15～25 ℃.
The present invention adopts freeze drying to combine with carbon dioxide supercritical extraction and extract placental hormone from placenta, operating temperature is the highest to be no more than 40 ℃, so the active component in the placental hormone that can guarantee to extract can inactivation, and because of adopting carbon dioxide supercritical extraction technology, the placental hormone that has in the placenta extracts advantage more completely.
The specific embodiment
Below in conjunction with specific embodiment placental hormone carbon dioxide supercritical extraction method of the present invention is described further.
The placenta that will obtain under aseptic condition carries out freeze drying under aseptic condition, through vacuum freeze drying 5～6h, be ground into 100 order fine powders under-5 ℃～-6 ℃ conditions; The placenta fine powder is added in the extraction kettle, and feeding pressure is the carbon dioxide of 30～40Mpa, extracts 8～12h under 30～40 ℃ of conditions; Through the one-level decompression separation, operating pressure is 8～12Mpa, and operating temperature is 30～35 ℃; Separate through second depressurized, condition is below the operating pressure 6Mpa again, and operating temperature is 15～25 ℃.Product after the collection decompression separation promptly gets placental hormone.
Claims (1)
1, a kind of placental hormone carbon dioxide supercritical extraction method in turn includes the following steps:
(1) with placenta process freeze drying 5～6h under-5 ℃～-6 ℃ conditions, pulverize;
(2) the placenta powder is packed in the extraction kettle, feed the carbon dioxide of 30～40Mpa, under 30～40 ℃ of conditions, extract;
(3) carry out second depressurized and separate, obtain placental hormone, one-level decompression separation condition is operating pressure 8～12Mpa, and temperature is 30～35 ℃; The second depressurized separation condition be operating pressure below 6Mpa, temperature is 15～25 ℃.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100969740A CN1289164C (en) | 2004-12-07 | 2004-12-07 | Carbon dioxide supercritical extraction method for placenta extract |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100969740A CN1289164C (en) | 2004-12-07 | 2004-12-07 | Carbon dioxide supercritical extraction method for placenta extract |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1634627A CN1634627A (en) | 2005-07-06 |
| CN1289164C true CN1289164C (en) | 2006-12-13 |
Family
ID=34847907
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2004100969740A Expired - Fee Related CN1289164C (en) | 2004-12-07 | 2004-12-07 | Carbon dioxide supercritical extraction method for placenta extract |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1289164C (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101306019B (en) * | 2007-05-15 | 2012-05-16 | 陈包容 | Hyper-concentrated placenta nano viable cell freeze-drying capsules and its preparation method |
| TWI645038B (en) * | 2016-04-29 | 2018-12-21 | 國為生醫科技股份有限公司 | Preparation method of placental active ingredient capable of improving stem cell survival rate |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI625123B (en) * | 2014-03-31 | 2018-06-01 | Method for isolating estrogen in placenta | |
| TWI526215B (en) * | 2014-08-25 | 2016-03-21 | Methods for separating functional constituents from the placenta | |
| TWI526216B (en) * | 2014-09-16 | 2016-03-21 | The method of separating and purifying functional components in placenta by supercritical fluid technology |
-
2004
- 2004-12-07 CN CNB2004100969740A patent/CN1289164C/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101306019B (en) * | 2007-05-15 | 2012-05-16 | 陈包容 | Hyper-concentrated placenta nano viable cell freeze-drying capsules and its preparation method |
| TWI645038B (en) * | 2016-04-29 | 2018-12-21 | 國為生醫科技股份有限公司 | Preparation method of placental active ingredient capable of improving stem cell survival rate |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1634627A (en) | 2005-07-06 |
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