CN1634627A - Carbon dioxide supercritical extraction method for placenta extract - Google Patents
Carbon dioxide supercritical extraction method for placenta extract Download PDFInfo
- Publication number
- CN1634627A CN1634627A CNA2004100969740A CN200410096974A CN1634627A CN 1634627 A CN1634627 A CN 1634627A CN A2004100969740 A CNA2004100969740 A CN A2004100969740A CN 200410096974 A CN200410096974 A CN 200410096974A CN 1634627 A CN1634627 A CN 1634627A
- Authority
- CN
- China
- Prior art keywords
- placenta
- carbon dioxide
- extract
- temperature
- under
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
This invention discloses a placenta carbon dioxide super threshold extraction method, which comprises the following steps: freezing and drying the placenta under temperature of -5DEG C ~-6DEG C for five to six hours and grinding it into powder; putting the powder into the extraction kettle and drawing carbon dioxide of 30~40Mpa under temperature of 30~40DEG C for extraction; processing two degree decompression isolation to get the placenta under 8~12Mpa and temperature of 30~35DEG C of first decompression isolation and under 6Mpa and temperature of 15~25DEG C of second degree decompression isolation.
Description
Technical field
The present invention relates to extract from the human placenta method of Placenta extract, is a kind of method that adopts the carbon dioxide supercritical fluid extraction technology to extract Placenta extract.
Background technology
Placenta Hominis Chinese medicine is called Placenta Hominis, has the adjusting function of human body, can build up resistance the effect of strongly invigorating primordial QI essence and blood.Placenta extract is the medicinal component that extracts from Placenta Hominis, contains multiple hormone and enzyme.At present, the decocting and concentrating method is adopted in the extraction of Placenta extract more, the Placenta extract amount that this method not only can extract is few, and energy consumption is big, cost is high, and some active gene regulatory factors in the Placenta Hominis and part metabolic regulation enzyme can reduce the value of Placenta extract because of the high temperature action inactivation.
Summary of the invention
At existing Placenta extract extracting method above shortcomings, the object of the present invention is to provide a kind of new Placenta extract extracting method, by the Placenta extract in the carbon dioxide supercritical fluid extraction extraction Placenta Hominis, not only cost is low, and can keep the activity of bioactive ingredients in the Placenta extract.
Carbon dioxide supercritical extraction method for placenta extract of the present invention in turn includes the following steps:
(1) with Placenta Hominis process lyophilization 5～6h under-5 ℃～-6 ℃ conditions, pulverize;
(2) the Placenta Hominis powder is packed in the extraction kettle, feed the carbon dioxide of 30～40Mpa, under 30～40 ℃ of conditions, extract;
(3) carry out second depressurized and separate, obtain Placenta extract, one-level decompression separation condition is operating pressure 8～12Mpa, and temperature is 30～35 ℃; The second depressurized separation condition be operating pressure below 6 Mpa, temperature is 15～25 ℃.
The present invention adopts lyophilization to combine with carbon dioxide supercritical fluid extraction and extract Placenta extract from Placenta Hominis, operative temperature is the highest to be no more than 40 ℃, so the active component in the Placenta extract that can guarantee to extract can inactivation, and because of adopting carbon dioxide supercritical fluid extraction technology, the Placenta extract that has in the Placenta Hominis extracts advantage more completely.
The specific embodiment
Below in conjunction with specific embodiment Placenta extract carbon dioxide supercritical fluid extraction method of the present invention is described further.
The Placenta Hominis that will obtain under aseptic condition carries out lyophilization under aseptic condition, through vacuum lyophilization 5～6h, be ground into 100 order fine powders under-5 ℃～-6 ℃ conditions; The Placenta Hominis fine powder is added in the extraction kettle, and feeding pressure is the carbon dioxide of 30～40Mpa, extracts 8～12h under 30～40 ℃ of conditions; Through the one-level decompression separation, operating pressure is 8～12Mpa, and operative temperature is 30～35 ℃; Separate through second depressurized, condition is below the operating pressure 6Mpa again, and operative temperature is 15～25 ℃.Product after the collection decompression separation promptly gets Placenta extract.
Claims (1)
1, a kind of Placenta extract carbon dioxide supercritical fluid extraction method in turn includes the following steps:
(1) with Placenta Hominis process lyophilization 5～6h under-5 ℃～-6 ℃ conditions, pulverize;
(2) the Placenta Hominis powder is packed in the extraction kettle, feed the carbon dioxide of 30～40Mpa, under 30～40 ℃ of conditions, extract;
(3) carry out second depressurized and separate, obtain Placenta extract, one-level decompression separation condition is operating pressure 8～12Mpa, and temperature is 30～35 ℃; The second depressurized separation condition be operating pressure below 6Mpa, temperature is 15～25 ℃.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100969740A CN1289164C (en) | 2004-12-07 | 2004-12-07 | Carbon dioxide supercritical extraction method for placenta extract |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100969740A CN1289164C (en) | 2004-12-07 | 2004-12-07 | Carbon dioxide supercritical extraction method for placenta extract |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1634627A true CN1634627A (en) | 2005-07-06 |
| CN1289164C CN1289164C (en) | 2006-12-13 |
Family
ID=34847907
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2004100969740A Expired - Fee Related CN1289164C (en) | 2004-12-07 | 2004-12-07 | Carbon dioxide supercritical extraction method for placenta extract |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1289164C (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104940235A (en) * | 2014-03-31 | 2015-09-30 | 超康生物科技股份有限公司 | Method for separating estrogen from placenta |
| CN105362294A (en) * | 2014-08-25 | 2016-03-02 | 超康生物科技股份有限公司 | Method for separating functional components from placenta |
| CN105748524A (en) * | 2014-09-16 | 2016-07-13 | 超康生物科技股份有限公司 | Method for separating and purifying functional components in placenta by supercritical fluid technology |
| CN107334704A (en) * | 2016-04-29 | 2017-11-10 | 超微体生医科技股份有限公司 | Preparation method of placenta active ingredient capable of improving survival rate of stem cells |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101306019B (en) * | 2007-05-15 | 2012-05-16 | 陈包容 | Hyper-concentrated placenta nano viable cell freeze-drying capsules and its preparation method |
-
2004
- 2004-12-07 CN CNB2004100969740A patent/CN1289164C/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104940235A (en) * | 2014-03-31 | 2015-09-30 | 超康生物科技股份有限公司 | Method for separating estrogen from placenta |
| CN105362294A (en) * | 2014-08-25 | 2016-03-02 | 超康生物科技股份有限公司 | Method for separating functional components from placenta |
| CN105748524A (en) * | 2014-09-16 | 2016-07-13 | 超康生物科技股份有限公司 | Method for separating and purifying functional components in placenta by supercritical fluid technology |
| CN107334704A (en) * | 2016-04-29 | 2017-11-10 | 超微体生医科技股份有限公司 | Preparation method of placenta active ingredient capable of improving survival rate of stem cells |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1289164C (en) | 2006-12-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103750328B (en) | A kind of freeze drying compound berry Ultramicro-powder and production method thereof | |
| CN104435743A (en) | Method for preparing dendrobium officinale super micropowder | |
| CN105343128A (en) | Processing method of sheep placenta instant powder | |
| CN105476939A (en) | Transdermal-absorption and metabolism-promoting mask essence | |
| CN101139543A (en) | Method for extracting sheep placental extract grease by over-critical carbon dioxide | |
| CN108671148A (en) | A kind of dendrobium candidum leaf effervescent and preparation method thereof | |
| CN103550262B (en) | A kind of extracting method of Cordyceps essence substance | |
| CN103169095B (en) | Method for preparing barbary wolfberry fruit powder by adding chrysanthemum extract liquid | |
| CN1634627A (en) | Carbon dioxide supercritical extraction method for placenta extract | |
| CN102784174A (en) | Process for preparing Chinese caterpillar fungus micropowder and preparation thereof | |
| CN110151860A (en) | A kind of preparation method and its usage of black fruit fructus lycii extract | |
| CN102492541B (en) | Method for extracting rose hip oil by supercritical carbon dioxide | |
| CN102599436A (en) | Production method of high-activity nattokinase and natto powder | |
| CN105851324A (en) | Instant black tea powder and preparing method thereof | |
| CN105558257A (en) | Method for extracting tuna small molecule peptides from tuna bones and application of tuna small molecule peptides | |
| CN102940688A (en) | Extraction method for polysaccharides and total flavonoids in fig leaves | |
| CN106387891B (en) | Saussurea involucrata culture ginseng nutrition powder and preparation method thereof | |
| CN105506043A (en) | Sea eel small molecular peptide extracted from sea eel bones and extraction method thereof | |
| CN104824781A (en) | Healthcare food recipe for enhancing appetite and making method thereof | |
| CN106832040B (en) | A kind of extracting method of lentinan | |
| CN102309693A (en) | Preparation method of total flavones of bitter bamboo leaves | |
| CN104855864A (en) | Health food formula with function of increasing appetite and preparation method thereof | |
| CN105053373A (en) | Dendrobe health-care tea | |
| CN110652463A (en) | Novel medical skin care product intermediate compound anthocyanin | |
| CN103479679A (en) | Enalapril compound preparation and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |