CN103550262B - A kind of extracting method of Cordyceps essence substance - Google Patents
A kind of extracting method of Cordyceps essence substance Download PDFInfo
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Abstract
The present invention discloses a kind of extracting method of Cordyceps essence substance, comprises the steps: pretreatment and the purified water of (1) Cordyceps; (2) Cordyceps pretreatment obtained and pure water extract; (3) be separated carrying out precision after the coarse filtration of cooled Cordyceps soup; (4) be 0.25-0.45um micro-pore-film filtration with aperture again by secondary filter liquid; (5) polishing purification liquid reverse osmosis membrane is concentrated at normal temperatures; (6) the Cordyceps soup concentrated through reverse osmosis membrane is carried out concentrating under reduced pressure again; (7) elite extract is finally obtained.Compared with prior art, the extracting method of Cordyceps essence substance provided by the invention, extract the elite of Cordyceps, greatly promote nutrition absorption rate, there is high efficiency, environmental protection, safety and guarantee the advantages such as effective ingredient activity, both maintained taste and the nutrient of Cordyceps, be easy to carry again, famous and precious Cordyceps efficacy effect can have been brought into play completely.
Description
Technical field
The present invention relates to field of health care products, exactly refer to a kind of extracting method of Cordyceps essence substance.
Background technology
Cordyceps is the traditional famous and precious medicated nourishing product of China, the flat sweet in the mouth of its property, has tonifying the lung kidney, cough-relieving is coughed, benefit is deficient, supports the function of vital essence.Nutrition contained by Cordyceps: aminoacid, sterol, mannitol, alkaloid, vitamin B1, B2, polysaccharide and mineral etc.According to clinical research, Cordyceps has ten large functions and has foster lung yin, and kidney-replenishing, relieving cough and resolving phlegm, anticancer anti-old effect are the product of flat nourishing YIN sun, allly avoid that (men and women, old and young can eat without institute, be the widest tonic of applicable crowd, and do not need to avoid certain food, have tonification greatly to health, mend marrow lung benefiting kidney, and the property of medicine is gentle, not attending a meeting like people, that people is produced is scorching, have Radix Ginseng benefit and without the evil of Radix Ginseng).Also can be used for pulmonary tuberculosis hemoptysis, the diseases such as impotence and seminal emission, as DONGBAO GANTAI, hundred Siberian cocklebur capsules, JINSHUIBAO.
Root it is documented that Cordyceps has following effect: 1. antibacterial, and 2. immunomodulating is 3. anticancer, 4. antiinflammatory, 5. nourishing kidney, 6. improves adrenal cortex alcohol content, 7. arrhythmia, 8. resisting fatigue, 9. eliminating phlegm and relieving asthma, 10. tranquilizing soporific.
" Bencao Congxin ": " protect lung kidney tonifying, hemostasis and phlegm, chronic cough.”
" property of medicine is examined ": " secret lean gas, specially mends the gate of vitality.”
" the little knowledge in Citrus chachiensis Hort. garden ": " eat it with steeping in wine number piece, control pain between waist knee joint, have the merit of kidney tonifying.”
" detailed outline is picked up any lost article from the road ": " Pan You new kumoharu diaphragm disease, scholar's kumoharu distention of the abdomen caused by various parasites of holding concurrently in week.”
" modern Practical Chinese medicinal ": " be applicable to the chronic cough asthma that pulmonary tuberculosis, old man are weak, haematemesis, night sweat, spontaneous perspiration; Weak for anemia again, impotence and seminal emission, old man's fear of cold, the cards such as the many lacrimations of tears.”
" Yunnan Chinese herbal medicine ": " tonifying the lung, invigorating kidney-YANG.Control expectorant to breath with cough.”
At present, most Cordyceps eating method is for cooking on the market, steeps in wine or fricassee, but above directly eating method can only absorb 20 to four ten of hundred parts of Cordyceps nutrition, central hundred parts 60 to eight ten will therefore to waste.Owing to digging in the middle of a Cordyceps, the minimum turf that will destroy about 30 square centimeters, excavate in process trampleed on, car grind area then larger.Except vegetation deterioration, thousands of people excavates the cavity stayed, and greatly accelerates the speed of soil erosion in rainy season.Because certain injury ought be made to the Nature at mining process, waste very much so continue to use current eating method to eat Cordyceps.
Summary of the invention
For above-mentioned defect, the technical problem that the present invention solves is the extracting method providing a kind of Cordyceps essence substance, extract the elite of Cordyceps, greatly promote nutrition absorption rate, there is high efficiency, environmental protection, safety and guarantee the advantages such as effective ingredient activity, both maintained taste and the nutrient of Cordyceps, be easy to carry again, famous and precious Cordyceps efficacy effect can have been brought into play completely.
In order to solve above technical problem, the extracting method of Cordyceps essence substance provided by the invention, comprises the steps:
(1) pretreatment of Cordyceps, removes the impurity staff on Cordyceps surface, and pulverize Cordyceps at the temperature pulverizer lower than 60 DEG C, fineness requirement is at 8 orders or following, and particle diameter is the smaller the better; Extraction is processed with former water, uses the pure water removing ion;
(2) Cordyceps pretreatment obtained and pure water are in the Cordyceps of 1:8-1:15 weight portion and water ratio, water temperature extracts at 20 DEG C-50 DEG C, and extraction is carried out 2-4 time, each 10-60 minute, the Cordyceps soup filtered out after extraction is several times merged, cools at ambient temperature;
(3) being separated carrying out precision after the coarse filtration of cooled Cordyceps soup, by aperture at the accurate membrane filtration of 3-10um, obtaining the secondary filter liquid of Cordyceps soup;
(4) be 0.25-0.45um micro-pore-film filtration with aperture again by secondary filter liquid, obtain the polishing purification liquid of Cordyceps soup;
(5) polishing purification liquid reverse osmosis membrane is concentrated at normal temperatures, obtain the concentrated Cordyceps soup that solid content is 8-15%;
(6) the Cordyceps soup will concentrated through reverse osmosis membrane, then carry out concentrating under reduced pressure, adopt the low temperature of 40 DEG C-50 DEG C, Cordyceps soup being concentrated to solid content is 50-70%;
(7) concentrated solution is carried out microwave vacuum low-temperature drying, vacuum lyophilization or spray-dired mode, finally obtain elite extract.
Preferably, in step (1), with pulverizer, Cordyceps is pulverized at the temperature of 20-50 DEG C.
Preferably, described elite extract makes electuary, tablet or capsule.
Preferably, the residue obtained after microwave vacuum low-temperature drying, vacuum lyophilization or spraying dry is made highland barley biscuit.
Compared with prior art, the extracting method of Cordyceps essence substance provided by the invention, the elite using low-temperature extraction isolation technics to extract Cordyceps can bring up to hundred parts 70%, low-temperature extraction isolation technics is by the low-temperature extraction technology in conjunction with shearing and vibration force effect, combined type microwave-assisted extraction technique and supercritical carbon dioxide extraction isolation technics three technology are integrated and are formed, this technology can carry out combination adjustment according to the characteristic of raw material and product demand, there is high efficiency, environmental protection, safety with guarantee the advantages such as effective ingredient is active, the scope of application is quite extensive, operative temperature is lower than 60 DEG C, the activity of effective ingredient in natural goods can be guaranteed, do not use the solvent of harmful human body, carry out extract and separate in an economical manner, can fully retain its effective ingredient and fragrance, equipment is easy to amplify, emphasizing the modern life that is healthy and health preserving, coordinate low-temperature extraction isolation technics the efficacy exertion of Cordyceps to maximum, greatly promote nutrition absorption rate, there is high efficiency, environmental protection, safety with guarantee the advantages such as effective ingredient is active, both taste and the nutrient of Cordyceps had been maintained, be easy to carry again, famous and precious Cordyceps efficacy effect can be brought into play completely.
Accompanying drawing explanation
Fig. 1 is the flow chart of the extracting method of Cordyceps essence substance in the present invention.
Detailed description of the invention
In order to those skilled in the art can understand technical scheme provided by the present invention better, set forth below in conjunction with specific embodiment.
Refer to Fig. 1, this figure is the structural representation of the extracting method of Cordyceps essence substance in the present invention.
Embodiment 1
The extracting method of the Cordyceps essence substance that the embodiment of the present invention provides, comprises the steps:
(1) pretreatment of Cordyceps, removes the impurity staff on Cordyceps surface, and pulverize Cordyceps at the temperature pulverizer of 50 DEG C, fineness requirement is at 8 orders; Extraction is processed with former water, uses the pure water removing ion;
(2) Cordyceps pretreatment obtained and pure water are in the Cordyceps of 1:8 weight portion and water ratio, and water temperature extracts at 20 DEG C, and extraction carries out 3 times, each 30 minutes, and the Cordyceps soup filtered out after extracting 4 times merges, and cools at ambient temperature;
(3) being separated carrying out precision after the coarse filtration of cooled Cordyceps soup, by aperture at the accurate membrane filtration of 8um, obtaining the secondary filter liquid of Cordyceps soup;
(4) be 0.25um micro-pore-film filtration with aperture again by secondary filter liquid, obtain the polishing purification liquid of Cordyceps soup;
(5) polishing purification liquid reverse osmosis membrane is concentrated at normal temperatures, obtain the concentrated Cordyceps soup that solid content is 10%;
(6) the Cordyceps soup will concentrated through reverse osmosis membrane, then carry out concentrating under reduced pressure, adopt the low temperature of 50 DEG C, Cordyceps soup being concentrated to solid content is 70%;
(7) concentrated solution is carried out microwave vacuum low-temperature drying, vacuum lyophilization or spray-dired mode, finally obtain elite extract, elite extract makes electuary; The residue obtained after microwave vacuum low-temperature drying, vacuum lyophilization or spraying dry is made highland barley biscuit.
For 10 grams of Cordyceps, have 72% with the elite that low-temperature extraction isolation technics is extracted wherein, only remaining 28% residue.
Embodiment 2
The extracting method of the Cordyceps essence substance that the embodiment of the present invention provides, comprises the steps:
(1) pretreatment of Cordyceps, removes the impurity staff on Cordyceps surface, and pulverize Cordyceps at the temperature pulverizer of 30 DEG C, fineness requirement is at 20 orders; Extraction is processed with former water, uses the pure water removing ion;
(2) Cordyceps pretreatment obtained and pure water are in the Cordyceps of 1:15 weight portion and water ratio, and water temperature extracts at 50 DEG C, and extraction carries out 4 times, each 60 minutes, and the Cordyceps soup filtered out after extracting 4 times merges, and cools at ambient temperature;
(3) being separated carrying out precision after the coarse filtration of cooled Cordyceps soup, by aperture at the accurate membrane filtration of 10um, obtaining the secondary filter liquid of Cordyceps soup;
(4) be 0.45um micro-pore-film filtration with aperture again by secondary filter liquid, obtain the polishing purification liquid of Cordyceps soup;
(5) polishing purification liquid reverse osmosis membrane is concentrated at normal temperatures, obtain the concentrated Cordyceps soup that solid content is 15%;
(6) the Cordyceps soup will concentrated through reverse osmosis membrane, then carry out concentrating under reduced pressure, adopt the low temperature of 50 DEG C, Cordyceps soup being concentrated to solid content is 50%;
(7) concentrated solution is carried out microwave vacuum low-temperature drying, vacuum lyophilization or spray-dired mode, finally obtain elite extract, elite extract makes capsule; The residue obtained after microwave vacuum low-temperature drying, vacuum lyophilization or spraying dry is made highland barley biscuit.
For 10 grams of Cordyceps, have 70% with the elite that low-temperature extraction isolation technics is extracted wherein, only remaining 30% residue.
Embodiment 3
The extracting method of the Cordyceps essence substance that the embodiment of the present invention provides, comprises the steps:
(1) pretreatment of Cordyceps, removes the impurity staff on Cordyceps surface, and pulverize Cordyceps at the temperature pulverizer of 20 DEG C, fineness requirement is at 100 orders; Extraction is processed with former water, uses the pure water removing ion;
(2) Cordyceps pretreatment obtained and pure water are in the Cordyceps of 1:12 weight portion and water ratio, and water temperature extracts at 40 DEG C, and extraction carries out 2 times, each 30 minutes, and the Cordyceps soup filtered out after extracting 2 times merges, and cools at ambient temperature;
(3) being separated carrying out precision after the coarse filtration of cooled Cordyceps soup, by aperture at the accurate membrane filtration of 5um, obtaining the secondary filter liquid of Cordyceps soup;
(4) be 0.35um micro-pore-film filtration with aperture again by secondary filter liquid, obtain the polishing purification liquid of Cordyceps soup;
(5) polishing purification liquid reverse osmosis membrane is concentrated at normal temperatures, obtain the concentrated Cordyceps soup that solid content is 10%;
(6) the Cordyceps soup will concentrated through reverse osmosis membrane, then carry out concentrating under reduced pressure, adopt the low temperature of 45 DEG C, Cordyceps soup being concentrated to solid content is 60%;
(7) concentrated solution is carried out microwave vacuum low-temperature drying, vacuum lyophilization or spray-dired mode, finally obtain elite extract, elite extract makes tablet; The residue obtained after microwave vacuum low-temperature drying, vacuum lyophilization or spraying dry is made highland barley biscuit.
For 10 grams of Cordyceps, have 75% with the elite that low-temperature extraction isolation technics is extracted wherein, only remaining 25% residue.
Compared with prior art, the extracting method of Cordyceps essence substance provided by the invention, the elite using low-temperature extraction isolation technics to extract Cordyceps can bring up to hundred parts 70%, low-temperature extraction isolation technics is by the low-temperature extraction technology in conjunction with shearing and vibration force effect, combined type microwave-assisted extraction technique and supercritical carbon dioxide extraction isolation technics three technology are integrated and are formed, this technology can carry out combination adjustment according to the characteristic of raw material and product demand, there is high efficiency, environmental protection, safety with guarantee the advantages such as effective ingredient is active, the scope of application is quite extensive, operative temperature is lower than 60 DEG C, the activity of effective ingredient in natural goods can be guaranteed, do not use the solvent of harmful human body, carry out extract and separate in an economical manner, can fully retain its effective ingredient and fragrance, equipment is easy to amplify, emphasizing the modern life that is healthy and health preserving, coordinate low-temperature extraction isolation technics the efficacy exertion of Cordyceps to maximum, greatly promote nutrition absorption rate, there is high efficiency, environmental protection, safety with guarantee the advantages such as effective ingredient is active, both taste and the nutrient of Cordyceps had been maintained, be easy to carry again, famous and precious Cordyceps efficacy effect can be brought into play completely.
To the above-mentioned explanation of the disclosed embodiments, professional and technical personnel in the field are realized or uses the present invention.To be apparent for those skilled in the art to the multiple amendment of these embodiments, General Principle as defined herein can without departing from the spirit or scope of the present invention, realize in other embodiments.Therefore, the present invention can not be restricted to these embodiments shown in this article, but will meet the widest scope consistent with principle disclosed herein and features of novelty.
Claims (4)
1. an extracting method for Cordyceps essence substance, is characterized in that, comprises the steps:
(1) pretreatment of Cordyceps, removes the impurity staff on Cordyceps surface, and pulverize Cordyceps at the temperature pulverizer lower than 60 DEG C, fineness requirement is at 8 orders or following; Extraction is processed with former water, uses the pure water removing ion;
(2) Cordyceps pretreatment obtained and pure water are in the Cordyceps of 1:8-1:15 weight portion and water ratio, water temperature extracts at 20 DEG C-50 DEG C, and extraction is carried out 2-4 time, each 10-60 minute, the Cordyceps soup filtered out after extraction is several times merged, cools at ambient temperature;
(3) being separated carrying out precision after the coarse filtration of cooled Cordyceps soup, by aperture at 3-10 μm of accurate membrane filtration, obtaining the secondary filter liquid of Cordyceps soup;
(4) be 0.25-0.45 μm of micro-pore-film filtration with aperture again by secondary filter liquid, obtain the polishing purification liquid of Cordyceps soup;
(5) polishing purification liquid reverse osmosis membrane is concentrated at normal temperatures, obtain the concentrated Cordyceps soup that solid content is 8-15%;
(6) the Cordyceps soup will concentrated through reverse osmosis membrane, then carry out concentrating under reduced pressure, adopt the low temperature of 40 DEG C-50 DEG C, Cordyceps soup being concentrated to solid content is 50-70%;
(7) concentrated solution is carried out microwave vacuum low-temperature drying, vacuum lyophilization or spray-dired mode, finally obtain elite extract.
2. the extracting method of Cordyceps essence substance according to claim 1, is characterized in that, in step (1), pulverizes at the temperature of 20-50 DEG C with pulverizer to Cordyceps.
3. the extracting method of Cordyceps essence substance according to claim 1, is characterized in that, described elite extract makes electuary, tablet or capsule.
4. the extracting method of Cordyceps essence substance according to claim 1, is characterized in that, the residue obtained after microwave vacuum low-temperature drying, vacuum lyophilization or spraying dry is made highland barley biscuit.
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| CN104072559B (en) * | 2014-05-08 | 2016-05-11 | 烟台市大成草生物科技有限公司 | A kind of method of extracting cordycepin from Cordyceps militaris |
| CN104382852A (en) * | 2014-11-15 | 2015-03-04 | 北京红百华科技有限公司 | Preparation method of cordyceps sinensis polysaccharide emulsion |
| CN104542860B (en) * | 2014-12-31 | 2018-04-03 | 广东东阳光药业有限公司 | A kind of anti-fatigue health-caring biscuit |
| CN104909972A (en) * | 2015-05-30 | 2015-09-16 | 吴爱群 | Method for extracting amino acids in worm grass |
| CN107929114A (en) * | 2017-12-21 | 2018-04-20 | 隐纱化妆品有限公司 | The extracting method of Cordyceps extract used for cosmetic |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1759710A (en) * | 2005-11-09 | 2006-04-19 | 云南省农业机械研究所 | 'Puer' caffeine and processing method |
| CN102060898A (en) * | 2011-01-10 | 2011-05-18 | 中山大学 | Extraction method of cordycepin |
| CN102746355A (en) * | 2012-06-19 | 2012-10-24 | 吉林省起泰科技有限公司 | Method for extracting and separating cordycepin |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1759710A (en) * | 2005-11-09 | 2006-04-19 | 云南省农业机械研究所 | 'Puer' caffeine and processing method |
| CN102060898A (en) * | 2011-01-10 | 2011-05-18 | 中山大学 | Extraction method of cordycepin |
| CN102746355A (en) * | 2012-06-19 | 2012-10-24 | 吉林省起泰科技有限公司 | Method for extracting and separating cordycepin |
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