CN1274324C - Preparation method of Chinese medicinal eye drops for treating myopia - Google Patents

Abstract

The present invention provides a preparation method of traditional Chinese medicine eye drops for treating myopia for the technical field of traditional Chinese medicine. Chinese herbal medicine containing 200g of white chrysanthemum flower, 200g of honeysuckle flower, 200g of butterflybush flower, 200g of stir-fried inula japonica flower, 100g of safflower, 100g of Maojian tea, and the like is taken and then is place on a grating grid of a large marmite which is then tightly covered and sealed by the other marmite, and a thin layer of medicine frost exists in the upper marmite for use after being stored; 2g of musk are then taken and are extracted by distillation, about 0.028g of dark brown volatile oil is obtained, components are muskone, fatty resin, etc., and the volatile oil has special fragrance so as to need to be sealed and preserved for use; during preparation, 0.5g of medicine frost, 0.5g of anisodamine powder and 0.5g of borneol are put into 1000 ml of distilled water for dissolution, muskone liquid and a proper amount of boric acid are then added, the pH value of the eye drops is regulated to 6.75, the eye drops are filled in bottles after filtration by a negative ion exchanger and then is sealed for use after being sterilized at high pressure. Compared with the prior art, the traditional Chinese medicine eye drops have the advantages of simple medication, convenience, safety, good curative effect, low price and no side effect.

Description

A kind of preparation method for the treatment of near-sighted Chinese medicine collyrium

The present invention is dividing an application of " invention and created name: a kind of treatment myopia medicine pill and collyrium and preparation method thereof, application number: 02110496.4, applying date: on June 3rd, 2002 ".

Technical field:

The invention belongs to the Chinese medicine technical field, be specifically related to a kind of preparation method for the treatment of the Chinese medicine Chinese medicine collyrium of myopia.

Background technology:

Adolescent myopia is a kind of more common, it also is one of ophthalmic diseases of a kind of relatively refractory, be divided into pseudomyopia (physiological myopia), half true myopia (betweenness myopia), true myopia (organic myopia), their cardinal symptom is a visual deterioration, pseudomyopia and half true myopia are myope's main colonies, with the traditional Chinese medical science debate disease opinion control with the doctor trained in Western medicine etiology and pathology be theoretical foundation, differential diagnosis in tcm thinks that adolescent myopia is many because of due to " work with one's mind and ponder over; deficiency of yang of liver and kidney ", it is many because of eyelash shape muscular spasm that doctor trained in Western medicine is thought, improper with eye, do not form due to the good eye hygiene custom; In therapeutic process, the patient is generally reflected the Tropicamide myopia liquid medicine on the market, have certain effect to treating myopia, but some back ocular pain, puckery itch and pupil is very fast looses greatly is unfavorable for the raising of vision on the contrary.

Summary of the invention:

It is simple to the objective of the invention is to design a kind of medication, convenient and safe, curative effect is high, price is honest and clean, the preparation method of the Chinese medicine collyrium of the treatment myopia of having no side effect.

The present invention in order to achieve the above object, this Chinese medicine ingredients of the technical scheme of taking and content (hundred parts of ratios of weight) are: Flos Chrysanthemi, Flos Buddlejae, the content of processing Flos Inulae, Flos Lonicerae, Radix Polygoni Multiflori are 12%-15%, and the content of Fructus Lycii, Fructus Schisandrae Chinensis, Flos Carthami, careless Herba Dendrobii is 10%-12%.

Get Flos Chrysanthemi, Flos Buddlejae, process Flos Inulae, Flos Carthami, each 500g of Radix Polygoni Multiflori, Flos Carthami 300g, careless Herba Dendrobii 300g, Fructus Lycii 300g, Fructus Schisandrae Chinensis 300g, adopt steam distillation, all medicines are put into body, extract and contain volatile oil and alkaloidal crude drug, lead in water vapour and crude drug hot altogether, volatilization wet goods active drug composition and water vapour distill simultaneously, steam distillation and the pharmaceutical compositions that goes out can be exempted plant because of the heat-flash coking, make granule, or add Poria powder, Mel and make ball and loose, the infusion bottling is standby meticulously.

The preparation method of Chinese medicine collyrium is as follows: get Flos Chrysanthemi, Flos Lonicerae, Flos Buddlejae, process each 200g of Flos Inulae, Chinese herbal medicine such as Flos Carthami, each 100g of Maojian tea, clean airing, put into big marmite of reuse on the big marmite double-edged fine-toothed comb then, cover following big marmite completely sealing, roasted 6 hours with slow fire the back, after cooling marmite is opened, above the very thin medicine frost of one deck is arranged in the marmite, the collection back is standby.Get Moschus 2g again, refine with distillation, get the about 0.028g of burgundy volatile oil, composition is a muscone, and fatty resin etc. have special fragrance, and it is stand-by to seal preservation; During preparation, the distilled water of earlier medicine frost and Radix Anisodi Tangutici ground caustic, each 0.5g of Borneolum Syntheticum being permitted to put into 1000 milliliters dissolves, dissolve the back and add muscone liquid and an amount of boric acid, the ph value of regulating collyrium is 6.75, wherein muscone content is 0.12%-0.14%, medicine frost, Anisodamine, content of bornyl alcohol are 0.05%-0.1%, bottling after the anion exchanger filters, and the autoclaving rear enclosed is standby.

Because the present invention has taked technique scheme, compared with prior art, has the advantage that medication is simple, convenient and safe, curative effect is high, price is honest and clean, have no side effect.

This strain of Moschus Cervidae (cervicac) animal Moschus moschiferous, dry secretions in the pod of buck, originate in Sichuan, Tibet, pod is ovate hemisphere, diameter 6-7cm, thick about 2-3cm, length has brown or brown white animal hair, and the mid portion of nearly capsule has an open pore, the flat horizontal surface of capsule has draped over one's shoulders the thin animal skin of one deck, and this is a good merchantable brand.Its composition will be got the capable steam of Moschus 2g, distillation again, get the about 0.028g of Moschus burgundy volatile oil, form through refining, have special fragrance, the name muscone, volatile, seasoning should seal, effectiveness is spasmolytic, and is analeptic and cardiac tonic, is the principal agent of removing eyelash shape muscular spasm.

The Compendium of Materia Medica record: Flos Carthami, the hot temperature of abnormal smells from the patient, nontoxic, go into the heart and nourish heart, call its bitter temperature, the yang aspect of yin, so go into the heart, assistant is returned tissue regeneration promoting blood, uses stagnant blood more, and is few with nourishing blood.

Crude drug analysis: Flos Carthami is a Compositae, the rectification of name red Cymbidium ensifolium (L.) Sw., and composition contains coloring matter, and Flos Carthami worker glycoside and Flos Carthami flavochrome is arranged.

Process Flos Inulae and have another name called Herba Inulae, temperature is slightly poisonous, row expectorant water, and the wind syndrome of ocular connectors due to invasion of pathogenic wind of decaptitating is because of slightly poisonous event is processed with Rhizoma Zingiberis Recens.

Flos Lonicerae is a Caprifoliaceae.The Sheng Nong's herbal classic is top grade, and Flos Lonicerae just by name is the key medicine of the clear swollen poison that looses from ancient times, clearing away heat to improve acuity of vision, and composition is a bios.

Book on Chinese herbal medicine is through record: Flos Buddlejae, the hot temperature of abnormal smells from the patient is nontoxicly gone into lung Liver Channel, profit cardiopulmonary, relieving restlessness expectorant, liver heat removing and eyesight improving.

Development is monarch with the Moschus, and Flos Carthami, Flos Chrysanthemi are minister, and Flos Lonicerae, Flos Buddlejae are assistant, and the moxibustion Flos Inulae is for making, so the careful and precise curative effect height of prescription.It is the desirable medicine of treatment adolescent myopia.

According to the many characteristics of teenager morbidity, the eight guiding principles for diagnosis of, pathology solid in conjunction with the disease of primary disease, pathogenesis and the traditional Chinese medical science are debated the disease opinion and are controlled and be rationale, selected for use spasmolytic active, the Moschus of liver heat removing and eyesight improving, Flos Chrysanthemi, Flos Buddlejae, Flos Carthami, process Flos Inulae again Chinese medicine and western medicine such as flower, Flos Lonicerae, Anisodamine be the main bonded composite treatment in Chinese and Western, reached and imitated high, inexpensive, safe ready, the purpose that has no side effect.According to " interior warp ": " treating the disease affected not; preventive treatment of disease " anti-overweight the thought controlled and " wind is that all kinds of diseases and ailments are long " " hinder in the wind person, on be subjected to it earlier " theory, as the Flos Chrysanthemi of selecting for use, Moschus, the energy liver heat removing and eyesight improving, remove eyelash shape muscular spasm, thereby reach the purpose of false and half true myopia of treatment teenager.Put down in writing as " ophthalmology complete works ": Flos Chrysanthemi, Xin Gan, be slightly cold, go into the effect of lung Liver Channel, liver heat removing and eyesight improving, wind-dispelling heat-dissipating, heat-clearing and toxic substances removing; " Yaoxing Fu " record: Flos Chrysanthemi makes eye bright and clear wind syndrome of head, modern pharmacological research, and Flos Chrysanthemi contains volatile oil, is Borneolum Syntheticum, Camphora, Flos Chrysanthemi cyclic ketones in the oil, also has chrysanthemum glycoside, adenine, choline, mcg vitamin A etc. in addition.

Claims (1)

1, a kind of preparation method for the treatment of near-sighted Chinese medicine collyrium, it is characterized in that getting Flos Chrysanthemi, Flos Lonicerae, Flos Buddlejae, process each 200g of Flos Inulae, Flos Carthami, each 100g Chinese herbal medicine of Maojian tea, clean airing, put into then on the big marmite double-edged fine-toothed comb, another big marmite of reuse covers underlaid described big marmite completely sealing, and roasted 6 hours with slow fire the back, after cooling marmite is opened, the very thin medicine frost of one deck is arranged in the top marmite, and the collection back is standby; Get Moschus 2g again, refine with distillation, get burgundy volatile oil 0.028g, composition is muscone, fatty resin, and it is stand-by to seal preservation; During preparation, the distilled water of earlier above-mentioned medicine frost and Radix Anisodi Tangutici ground caustic, each 0.5g of Borneolum Syntheticum being put into 1000 milliliters dissolves, dissolve the back and add described volatile oil and an amount of boric acid, the ph value of regulating collyrium is 6.75, wherein muscone content is 0.12%-0.14%, medicine frost, Anisodamine, content of bornyl alcohol are 0.05%-0.1%, bottling after the anion exchanger filters, and the autoclaving rear enclosed is standby.